This is the analysis script to prepare the data to run analyses for the project “Anxiety, depression and trauma symptom change during the COVID-19 pandemic: retrospective versus objective assessment” - Young et al (2020)
Script written by K L Purves, K N Thompson, C Huebel and M Davies. Email: kirstin.purves@kcl.ac.uk, katie.thompson@kcl.ac.uk, christopher.1.huebel@kcl.ac.uk, molly.davies@kcl.ac.uk
#Set up
Clear global environment
Retrieve the current date to use it for file endings to not overwrite files when one exports files
#Packages Install packages (if they are not available in your version of R)
#Load packages
Registered S3 method overwritten by 'pryr':
method from
print.bytes Rcpp
For best results, restart R session and update pander using devtools:: or remotes::install_github('rapporter/pander')
Attaching package: 'polycor'
The following object is masked from 'package:psych':
polyserial
corrplot 0.84 loaded
── Attaching packages ─────────────────────────────────────── tidyverse 1.3.0 ──
✓ ggplot2 3.3.2 ✓ purrr 0.3.4
✓ tibble 3.0.4 ✓ dplyr 1.0.2
✓ tidyr 1.1.2 ✓ stringr 1.4.0
✓ readr 1.3.1 ✓ forcats 0.5.0
── Conflicts ────────────────────────────────────────── tidyverse_conflicts() ──
x ggplot2::%+%() masks psych::%+%()
x ggplot2::alpha() masks psych::alpha()
x dplyr::filter() masks stats::filter()
x dplyr::lag() masks stats::lag()
x tibble::view() masks summarytools::view()
Attaching package: 'cowplot'
The following object is masked from 'package:ggpubr':
get_legend
The following object is masked from 'package:patchwork':
align_plots
R functions
FunctionLib/lm_forest.R FunctionLib/lm_formula.R
value ? ?
visible FALSE FALSE
FunctionLib/lm_output.R FunctionLib/raincloud.R
value ? ?
visible FALSE FALSE
Half-violin plot
Colour palettes
Define colours for plotting this are the standard coping colours
Choose in this chunk which palette to use 04.07.2020 - Default to 2 colour COPING palette
ggplot theme
Set up ggplot theme for the plots
Data import
Source data file paths
Read in data
[1] 34465 643
Important vectors with collections of columns
Vectors for sum_score
[1] "gad.sum_score_prepan" "pcl.sum_score_prepan"
[3] "phq.sum_score_prepan" "phq.sum_score_8items_prepan"
[5] "ocir.sum_score_prepan" "gad.sum_score_base"
[7] "gad.sum_score_retro" "pcl.sum_score_base"
[9] "pcl.sum_score_retro" "phq.sum_score_base"
[11] "phq.sum_score_8items_base" "phq.sum_score_retro"
[13] "phq.sum_score_8items_retro" "ocir.sum_score_base"
[15] "ocir.sum_score_retro"
[1] "phq.sum_score_prepan" "phq.sum_score_base" "phq.sum_score_retro"
[1] "gad.sum_score_prepan" "gad.sum_score_base" "gad.sum_score_retro"
[1] "ocir.sum_score_prepan" "ocir.sum_score_base" "ocir.sum_score_retro"
[1] "pcl.sum_score_prepan" "pcl.sum_score_base" "pcl.sum_score_retro"
Vectors for diff_score
[1] "phq.diff_score_retro_prepan" "phq.diff_score_base_prepan"
[3] "phq.diff_score_base_retro" "gad.diff_score_retro_prepan"
[5] "gad.diff_score_base_prepan" "gad.diff_score_base_retro"
[7] "pcl.diff_score_base_prepan" "ocir.diff_score_retro_prepan"
[9] "ocir.diff_score_base_prepan" "ocir.diff_score_base_retro"
[1] "phq.diff_score_retro_prepan" "phq.diff_score_base_prepan"
[3] "phq.diff_score_base_retro"
[1] "gad.diff_score_retro_prepan" "gad.diff_score_base_prepan"
[3] "gad.diff_score_base_retro"
[1] "ocir.diff_score_retro_prepan" "ocir.diff_score_base_prepan"
[3] "ocir.diff_score_base_retro"
Create subsets of data for analyses
Filter data frame to create 2 additional datasets. Additional exclusion criteria (beyond those listed above) are specified below:
- Retrospective - baseline change anlyses
- Exclude individuals missing retrospective and/or baseline data
- Prepandemic - baseline change analyses i. Exclude individuals missing pandemic and/or baseline data ii. Exclude individuals with prepandemic data collected after 1st March.
Retro-baseline analyses
Note: make sure we impute retrospective data for those who did not change their feelings
Important note::: PCL does not have retrospective data, so we allow Baseline only or All prepandemic, baseline and retrospective OR Baseline and prepandemic data. Important logic here is that we need EVRYONE with ANY baseline data, but dont care about any other time point for this retrospective dataset for PCL.
[1] 32737 643
Prepan-baseline analyses Exclude individuals with NA for MHD, age, gender; exclude if prepan data collected after 1 March
[1] 12157 643
Prepan-baseline analyses Exclude individuals with NA for MHD, age, gender; exclude if prepan data collected after 1 March (to ensure comparability with prepan analyses)
[1] 10489 643
age^2 sensitivity Exclude individuals with NA for continuous Age variable
[1] 25814 643
[1] 24096 643
[1] 12157 643
Sensitivity analysis for individuals who signed up to GLAD (prepan) either 3, 6 or 9 months before the pendemic began.
#ANALYSIS PLAN 1. Calculate mean change per disorder group i. Disorders (9) a. Rank the disorders by the size of the change ii. Sex iii. Age (13; RAMP; potentially collapse above 65 depending on group sizes) iv. Ethnicity groups (5; White European, Black (British), Asian, Arab, Mixed)
1. Questionnaire comparions: Calculate mean change per group
gad
Summary scores
Warning in min(., na.rm = T): no non-missing arguments to min; returning Inf
Warning in max(., na.rm = T): no non-missing arguments to max; returning -Inf
Table for knitting gad sum score summary table
| No change |
Base |
0 |
21 |
2.740042 |
1 |
4.481334 |
2.1348352 |
4.2519780 |
| No change |
Prepan |
0 |
21 |
7.993625 |
7 |
6.165962 |
0.5274724 |
-0.8425302 |
| No change |
Retro |
0 |
21 |
2.740042 |
1 |
4.481334 |
2.1348352 |
4.2519780 |
| Worsening |
Base |
0 |
21 |
8.766138 |
7 |
5.693132 |
0.5145419 |
-0.8093878 |
| Worsening |
Prepan |
0 |
21 |
9.160358 |
8 |
5.869416 |
0.3772128 |
-0.9054598 |
| Worsening |
Retro |
0 |
21 |
4.658218 |
4 |
4.263868 |
1.3773597 |
1.9563781 |
| Improvement |
Base |
0 |
21 |
4.767912 |
3 |
4.832619 |
1.3721605 |
1.5870653 |
| Improvement |
Prepan |
0 |
21 |
9.046937 |
8 |
5.804418 |
0.3595536 |
-0.8773999 |
| Improvement |
Retro |
0 |
21 |
8.337588 |
7 |
5.489836 |
0.5192540 |
-0.5883912 |
| NA |
Base |
0 |
21 |
5.722222 |
5 |
5.816102 |
1.0412406 |
0.2319193 |
| NA |
Prepan |
0 |
21 |
10.000000 |
13 |
8.563488 |
-0.0313927 |
-1.9895986 |
| NA |
Retro |
Inf |
-Inf |
NaN |
NA |
NA |
NA |
NA |
Differences scores
Warning in min(., na.rm = T): no non-missing arguments to min; returning Inf
Warning in min(., na.rm = T): no non-missing arguments to min; returning Inf
Warning in min(., na.rm = T): no non-missing arguments to min; returning Inf
Warning in min(., na.rm = T): no non-missing arguments to min; returning Inf
Warning in max(., na.rm = T): no non-missing arguments to max; returning -Inf
Warning in max(., na.rm = T): no non-missing arguments to max; returning -Inf
Warning in max(., na.rm = T): no non-missing arguments to max; returning -Inf
Warning in max(., na.rm = T): no non-missing arguments to max; returning -Inf
Table for knitting gad diff summary table
| No change |
Base - prepan |
-21 |
20 |
-2.0355457 |
-1 |
4.695963 |
-0.4873054 |
1.5249971 |
| No change |
Base - retro |
Inf |
-Inf |
NaN |
NA |
NA |
NA |
NA |
| No change |
Prepan - retro |
Inf |
-Inf |
NaN |
NA |
NA |
NA |
NA |
| Worsening |
Base - prepan |
-18 |
21 |
1.0244339 |
1 |
5.272565 |
-0.0232123 |
0.6264062 |
| Worsening |
Base - retro |
-21 |
21 |
4.1083717 |
3 |
4.319494 |
0.7492612 |
0.9033930 |
| Worsening |
Prepan - retro |
-21 |
18 |
-3.4649078 |
-3 |
5.071721 |
-0.3175882 |
0.4750981 |
| Improvement |
Base - prepan |
-21 |
12 |
-3.9601911 |
-3 |
5.470385 |
-0.2955275 |
0.1734936 |
| Improvement |
Base - retro |
-21 |
21 |
-3.5651408 |
-3 |
5.333376 |
0.4506964 |
2.0385927 |
| Improvement |
Prepan - retro |
-21 |
20 |
0.4334661 |
1 |
5.679098 |
-0.1488051 |
0.8650700 |
| NA |
Base - prepan |
-9 |
6 |
-1.5000000 |
-2 |
5.431390 |
0.0468089 |
-1.6798094 |
| NA |
Base - retro |
Inf |
-Inf |
NaN |
NA |
NA |
NA |
NA |
| NA |
Prepan - retro |
Inf |
-Inf |
NaN |
NA |
NA |
NA |
NA |
Plots diff
makes this into percentages
Warning: Removed 60925 rows containing non-finite values (stat_count).

Warning: Removed 35523 rows containing non-finite values (stat_bin).

Warning: Removed 35523 rows containing non-finite values (stat_bin).

Warning: Removed 25402 rows containing non-finite values (stat_bin).

Plots sum
Warning: Removed 21890 rows containing non-finite values (stat_bin).

Warning: Removed 21890 rows containing non-finite values (stat_bin).

Violin plots
Warning: `fun.y` is deprecated. Use `fun` instead.
Warning: `fun.ymin` is deprecated. Use `fun.min` instead.
Warning: `fun.ymax` is deprecated. Use `fun.max` instead.
Warning: Removed 21890 rows containing non-finite values (stat_ydensity).
Warning: Removed 21890 rows containing non-finite values (stat_summary).
Warning: Removed 21890 rows containing missing values (geom_point).

Warning: `fun.y` is deprecated. Use `fun` instead.
Warning: `fun.ymin` is deprecated. Use `fun.min` instead.
Warning: `fun.ymax` is deprecated. Use `fun.max` instead.
Warning: Removed 21890 rows containing non-finite values (stat_ydensity).
Warning: Removed 21890 rows containing non-finite values (stat_summary).
Warning: Removed 21890 rows containing missing values (geom_point).

Warning: `fun.y` is deprecated. Use `fun` instead.
Warning: `fun.ymin` is deprecated. Use `fun.min` instead.
Warning: `fun.ymax` is deprecated. Use `fun.max` instead.
Warning: Removed 21890 rows containing non-finite values (stat_ydensity).
Warning: Removed 21890 rows containing non-finite values (stat_summary).
Warning: Removed 21890 rows containing missing values (geom_point).

Warning: `fun.y` is deprecated. Use `fun` instead.
Warning: `fun.ymin` is deprecated. Use `fun.min` instead.
Warning: `fun.ymax` is deprecated. Use `fun.max` instead.
Warning: Removed 21890 rows containing non-finite values (stat_ydensity).
Warning: Removed 21890 rows containing non-finite values (stat_summary).
Warning: Removed 21890 rows containing missing values (geom_point).

phq
Summary scores
Warning in min(., na.rm = T): no non-missing arguments to min; returning Inf
Warning in max(., na.rm = T): no non-missing arguments to max; returning -Inf
Table for knitting phq sum score summary table
| No change |
Base |
0 |
27 |
3.911637 |
2 |
5.561495 |
1.9710470 |
3.5614983 |
| No change |
Prepan |
0 |
27 |
10.331368 |
9 |
7.165943 |
0.5042461 |
-0.7025645 |
| No change |
Retro |
0 |
27 |
3.911637 |
2 |
5.561495 |
1.9710470 |
3.5614983 |
| Worsening |
Base |
0 |
27 |
10.464944 |
9 |
6.597026 |
0.5728307 |
-0.5587612 |
| Worsening |
Prepan |
0 |
27 |
11.544677 |
11 |
6.734044 |
0.3283080 |
-0.7571665 |
| Worsening |
Retro |
0 |
27 |
5.764678 |
4 |
5.272585 |
1.4108842 |
1.9270712 |
| Improvement |
Base |
0 |
27 |
6.736196 |
5 |
5.756886 |
1.0578823 |
0.6962716 |
| Improvement |
Prepan |
0 |
27 |
11.416949 |
11 |
6.732361 |
0.3159912 |
-0.8068586 |
| Improvement |
Retro |
0 |
27 |
9.761905 |
9 |
6.750091 |
0.6105814 |
-0.4259463 |
| NA |
Base |
0 |
27 |
6.360760 |
4 |
7.081166 |
1.0612878 |
0.0689664 |
| NA |
Prepan |
0 |
25 |
10.675676 |
8 |
7.476088 |
0.5644682 |
-0.9990107 |
| NA |
Retro |
Inf |
-Inf |
NaN |
NA |
NA |
NA |
NA |
Differences score
Warning in min(., na.rm = T): no non-missing arguments to min; returning Inf
Warning in min(., na.rm = T): no non-missing arguments to min; returning Inf
Warning in min(., na.rm = T): no non-missing arguments to min; returning Inf
Warning in min(., na.rm = T): no non-missing arguments to min; returning Inf
Warning in max(., na.rm = T): no non-missing arguments to max; returning -Inf
Warning in max(., na.rm = T): no non-missing arguments to max; returning -Inf
Warning in max(., na.rm = T): no non-missing arguments to max; returning -Inf
Warning in max(., na.rm = T): no non-missing arguments to max; returning -Inf
Table for knitting phq diff summary table
| No change |
Base - prepan |
-25 |
23 |
-1.9953315 |
-1 |
5.121711 |
-0.3442067 |
1.7614748 |
| No change |
Base - retro |
Inf |
-Inf |
NaN |
NA |
NA |
NA |
NA |
| No change |
Prepan - retro |
Inf |
-Inf |
NaN |
NA |
NA |
NA |
NA |
| Worsening |
Base - prepan |
-23 |
24 |
0.8652563 |
1 |
5.564097 |
-0.0442397 |
0.8979642 |
| Worsening |
Base - retro |
-18 |
27 |
4.6967453 |
4 |
4.598109 |
0.8998863 |
1.2437470 |
| Worsening |
Prepan - retro |
-27 |
21 |
-4.1668767 |
-4 |
5.496903 |
-0.3745911 |
0.6142949 |
| Improvement |
Base - prepan |
-23 |
14 |
-4.0088195 |
-3 |
5.680142 |
-0.4391773 |
0.2052763 |
| Improvement |
Base - retro |
-24 |
23 |
-3.0184403 |
-3 |
5.566698 |
0.0409481 |
1.8189755 |
| Improvement |
Prepan - retro |
-27 |
22 |
-0.1250850 |
0 |
6.156186 |
-0.0477601 |
0.6905753 |
| NA |
Base - prepan |
-21 |
8 |
-0.5277778 |
0 |
5.794017 |
-1.1586641 |
2.3722947 |
| NA |
Base - retro |
Inf |
-Inf |
NaN |
NA |
NA |
NA |
NA |
| NA |
Prepan - retro |
Inf |
-Inf |
NaN |
NA |
NA |
NA |
NA |
Plots
makes this into percentages
Warning: Removed 59551 rows containing non-finite values (stat_count).

Warning: Removed 34491 rows containing non-finite values (stat_bin).

Warning: Removed 25060 rows containing non-finite values (stat_bin).

Warning: Removed 34491 rows containing non-finite values (stat_bin).

Plots sum
Warning: Removed 22031 rows containing non-finite values (stat_bin).

Warning: Removed 22031 rows containing non-finite values (stat_bin).

Violin plots
Warning: `fun.y` is deprecated. Use `fun` instead.
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Warning: `fun.ymax` is deprecated. Use `fun.max` instead.
Warning: Removed 22031 rows containing non-finite values (stat_ydensity).
Warning: Removed 22031 rows containing non-finite values (stat_summary).
Warning: Removed 22031 rows containing missing values (geom_point).

Warning: `fun.y` is deprecated. Use `fun` instead.
Warning: `fun.ymin` is deprecated. Use `fun.min` instead.
Warning: `fun.ymax` is deprecated. Use `fun.max` instead.
Warning: Removed 22031 rows containing non-finite values (stat_ydensity).
Warning: Removed 22031 rows containing non-finite values (stat_summary).
Warning: Removed 22031 rows containing missing values (geom_point).

Warning: `fun.y` is deprecated. Use `fun` instead.
Warning: `fun.ymin` is deprecated. Use `fun.min` instead.
Warning: `fun.ymax` is deprecated. Use `fun.max` instead.
Warning: Removed 22031 rows containing non-finite values (stat_ydensity).
Warning: Removed 22031 rows containing non-finite values (stat_summary).
Warning: Removed 22031 rows containing missing values (geom_point).

Warning: `fun.y` is deprecated. Use `fun` instead.
Warning: `fun.ymin` is deprecated. Use `fun.min` instead.
Warning: `fun.ymax` is deprecated. Use `fun.max` instead.
Warning: Removed 22031 rows containing non-finite values (stat_ydensity).
Warning: Removed 22031 rows containing non-finite values (stat_summary).
Warning: Removed 22031 rows containing missing values (geom_point).

ocir
Summary scores
Warning in min(., na.rm = T): no non-missing arguments to min; returning Inf
Warning in max(., na.rm = T): no non-missing arguments to max; returning -Inf
Table for knitting ocir sum score summary table
| Base |
0 |
72 |
18.16106 |
15 |
13.01856 |
1.111240 |
1.1222355 |
| Prepan |
1 |
71 |
27.05217 |
25 |
14.08570 |
0.636545 |
-0.0069965 |
| Retro |
0 |
71 |
16.76087 |
14 |
12.74079 |
1.120438 |
1.0346803 |
Differences scores
Table for knitting ocir diff summary table
| Base - prepan |
-40 |
34 |
-8.084711 |
-7 |
10.701437 |
-0.1437180 |
0.6496048 |
| Base - retro |
-44 |
72 |
1.466054 |
1 |
9.784785 |
0.2935243 |
2.3017255 |
| Prepan - retro |
-30 |
27 |
-3.596491 |
-3 |
9.288374 |
-0.0831304 |
0.3781195 |
Plots
makes this into percentages
Warning: Removed 96991 rows containing non-finite values (stat_count).

Warning: Removed 63438 rows containing non-finite values (stat_bin).

Warning: Removed 33553 rows containing non-finite values (stat_bin).

Warning: Removed 63438 rows containing non-finite values (stat_bin).

Plots sum
Warning: Removed 87674 rows containing non-finite values (stat_bin).

Warning: Removed 87674 rows containing non-finite values (stat_bin).

Violin plots
Warning: `fun.y` is deprecated. Use `fun` instead.
Warning: `fun.ymin` is deprecated. Use `fun.min` instead.
Warning: `fun.ymax` is deprecated. Use `fun.max` instead.
Warning: Removed 87674 rows containing non-finite values (stat_ydensity).
Warning: Removed 87674 rows containing non-finite values (stat_summary).
Warning: Removed 87674 rows containing missing values (geom_point).

Warning: `fun.y` is deprecated. Use `fun` instead.
Warning: `fun.ymin` is deprecated. Use `fun.min` instead.
Warning: `fun.ymax` is deprecated. Use `fun.max` instead.
Warning: Removed 87674 rows containing non-finite values (stat_ydensity).
Warning: Removed 87674 rows containing non-finite values (stat_summary).
Warning: Removed 87674 rows containing missing values (geom_point).

Warning: `fun.y` is deprecated. Use `fun` instead.
Warning: `fun.ymin` is deprecated. Use `fun.min` instead.
Warning: `fun.ymax` is deprecated. Use `fun.max` instead.
Warning: Removed 87674 rows containing non-finite values (stat_ydensity).
Warning: Removed 87674 rows containing non-finite values (stat_summary).
Warning: Removed 87674 rows containing missing values (geom_point).

Warning: `fun.y` is deprecated. Use `fun` instead.
Warning: `fun.ymin` is deprecated. Use `fun.min` instead.
Warning: `fun.ymax` is deprecated. Use `fun.max` instead.
Warning: Removed 87674 rows containing non-finite values (stat_ydensity).
Warning: Removed 87674 rows containing non-finite values (stat_summary).
Warning: Removed 87674 rows containing missing values (geom_point).

++CH: Rank the disorders by the size of the change
PCL: Calculate the total GLAD, COPING, RAMP baseline ## PCL
Table for knitting pcl sum score summary table
| Base - prepan |
-23 |
24 |
0.2218057 |
0 |
5.663535 |
-0.0680983 |
0.6666216 |
Table for knitting pcl diff summary table
| Base |
6 |
30 |
12.45841 |
11 |
6.036574 |
0.9034948 |
-0.0705604 |
| Prepan |
6 |
30 |
15.45255 |
15 |
6.109940 |
0.4074959 |
-0.7142112 |
For each item present percentages of how say that this is due to the pandemic
| pcl.cut_people_feeling_distant_retro_numeric |
0 |
6592 |
19.1 |
6592 (19.1%) |
| pcl.cut_people_feeling_distant_retro_numeric |
1 |
16928 |
49.1 |
16928 (49.1%) |
| pcl.cut_people_feeling_distant_retro_numeric |
Missing |
10945 |
31.8 |
10945 (31.8%) |
| pcl.difficulty_concentrating_retro_numeric |
0 |
10912 |
31.7 |
10912 (31.7%) |
| pcl.difficulty_concentrating_retro_numeric |
1 |
11352 |
32.9 |
11352 (32.9%) |
| pcl.difficulty_concentrating_retro_numeric |
Missing |
12201 |
35.4 |
12201 (35.4%) |
| pcl.feeling_irritable_or_having_angry_outbursts_retro_numeric |
0 |
9685 |
28.1 |
9685 (28.1%) |
| pcl.feeling_irritable_or_having_angry_outbursts_retro_numeric |
1 |
10903 |
31.6 |
10903 (31.6%) |
| pcl.feeling_irritable_or_having_angry_outbursts_retro_numeric |
Missing |
13877 |
40.3 |
13877 (40.3%) |
| pcl.stressful_experience_repeated_images_retro_numeric |
0 |
14517 |
42.1 |
14517 (42.1%) |
| pcl.stressful_experience_repeated_images_retro_numeric |
1 |
3204 |
9.3 |
3204 (9.3%) |
| pcl.stressful_experience_repeated_images_retro_numeric |
Missing |
16744 |
48.6 |
16744 (48.6%) |
| pcl.stressful_experience_upset_reminded_retro_numeric |
0 |
15284 |
44.3 |
15284 (44.3%) |
| pcl.stressful_experience_upset_reminded_retro_numeric |
1 |
4076 |
11.8 |
4076 (11.8%) |
| pcl.stressful_experience_upset_reminded_retro_numeric |
Missing |
15105 |
43.8 |
15105 (43.8%) |
| pcl.stressful_situation_avoiding_activities_retro_numeric |
0 |
10199 |
29.6 |
10199 (29.6%) |
| pcl.stressful_situation_avoiding_activities_retro_numeric |
1 |
2687 |
7.8 |
2687 (7.8%) |
| pcl.stressful_situation_avoiding_activities_retro_numeric |
Missing |
21579 |
62.6 |
21579 (62.6%) |
Plots sum
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Regression models (Regress covariates out of the change? Which?)
- Model 0: Disorders
- Model 1: Model 0 + Sex + Age + Ethnicity + Time registration and baseline
Re-calculate change
Re-rank the change again
PCL:
- Calculate the total GLAD, COPING, RAMP baseline
- For each item:
- present percentages of how say that this is due to the pandemic
- Calculate a variable PCL pandemic score
- If one item is highly endorsed due to pandemic -> exclude in sensitivity analysis
2. Regression
Regress covariates out of the change? Which?
Model naming conventions: 0 - unadjusted 1 - adjusted 2 - adjusted with age^2 a - hierarchical disorders b - overlapping disorder categories
++MD: We may want to exclude disorders from Model b that aren’t including in the hierarchy (e.g. ADHD, ASD)
Functions
GAD baseline, not controlling for prior symptoms
Model 0a: Disorder_hierarchical, Unadjusted
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
2.67 |
2.59 |
2.76 |
0.04 |
0.00e+00 |
| Depressive and anxiety disorder |
5.63 |
5.50 |
5.77 |
0.07 |
0.00e+00 |
| Only depressive disorder |
2.08 |
1.90 |
2.25 |
0.09 |
4.32e-117 |
| Only anxiety disorder |
4.03 |
3.81 |
4.26 |
0.11 |
1.97e-264 |
| Eating disorders |
1.46 |
1.22 |
1.69 |
0.12 |
1.10e-33 |
| OCDs |
1.94 |
1.71 |
2.17 |
0.12 |
8.53e-63 |
| Psychotic and bipolar disorder |
0.38 |
-0.26 |
1.02 |
0.33 |
0.24 |
| Only psychotic disorder |
0.35 |
-0.20 |
0.90 |
0.28 |
0.21 |
| Only bipolar disorder |
0.46 |
0.11 |
0.80 |
0.18 |
0.009 |
| PTSD |
1.56 |
1.35 |
1.77 |
0.11 |
2.35e-48 |
| ASD |
2.18 |
1.77 |
2.59 |
0.21 |
1.80e-25 |
| ADHD |
1.17 |
0.63 |
1.71 |
0.28 |
2.36e-05 |
| Personality disorder |
2.19 |
1.89 |
2.49 |
0.15 |
5.79e-46 |
| 32679 |
0.21 |
0.21 |
1485.53 |
0.00e+00 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
5.67 |
5.38 |
5.95 |
0.15 |
8.10e-322 |
| Anxiety disorders |
2.98 |
2.73 |
3.24 |
0.13 |
4.34e-113 |
| Eating disorders |
2.03 |
1.23 |
2.83 |
0.41 |
7.12e-07 |
| OCDs |
3.86 |
3.22 |
4.51 |
0.33 |
1.71e-31 |
| PTSD |
4.12 |
3.48 |
4.77 |
0.33 |
2.04e-36 |
| Depressive disorders |
4.43 |
4.30 |
4.57 |
0.07 |
0.00e+00 |
| Bipolar disorders |
5.91 |
5.60 |
6.22 |
0.16 |
1.45e-297 |
| Female |
1.01 |
0.87 |
1.15 |
0.07 |
5.89e-47 |
| Non-binary/Self-defined |
1.56 |
1.01 |
2.10 |
0.28 |
2.71e-08 |
| age_category_collapsed_reordered16-18 |
3.23 |
2.86 |
3.60 |
0.19 |
6.52e-66 |
| 19-25 years |
1.71 |
1.46 |
1.97 |
0.13 |
4.87e-40 |
| 36-45 years |
-0.83 |
-1.04 |
-0.62 |
0.11 |
1.54e-14 |
| 46-55 years |
-1.56 |
-1.75 |
-1.36 |
0.10 |
7.98e-55 |
| 56-65 years |
-2.58 |
-2.78 |
-2.39 |
0.10 |
9.71e-149 |
| 66-70 years |
-3.55 |
-3.80 |
-3.30 |
0.13 |
3.76e-172 |
| 71-75 years |
-3.77 |
-4.05 |
-3.48 |
0.15 |
6.98e-147 |
| 76+ years |
-3.74 |
-4.17 |
-3.31 |
0.22 |
3.16e-64 |
| Mixed or multiple ethnic origins |
0.01 |
-0.43 |
0.45 |
0.22 |
0.97 |
| Asian or Asian British |
-0.41 |
-0.95 |
0.13 |
0.28 |
0.13 |
| African or African British |
-0.26 |
-1.24 |
0.72 |
0.50 |
0.61 |
| Other ethnicity |
0.75 |
0.00 |
1.50 |
0.38 |
0.05 |
| Time difference: Lockdown to baseline |
-0.24 |
-0.27 |
-0.21 |
0.01 |
9.28e-58 |
| 32679 |
0.21 |
0.21 |
1485.53 |
0.00e+00 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
5.58 |
5.29 |
5.86 |
0.14 |
2.34e-318 |
| Depressive and anxiety disorder |
4.60 |
4.45 |
4.74 |
0.07 |
0.00e+00 |
| Only depressive disorder |
1.81 |
1.62 |
1.99 |
0.09 |
5.09e-83 |
| Only anxiety disorder |
3.04 |
2.81 |
3.28 |
0.12 |
2.89e-144 |
| Eating disorders |
0.90 |
0.67 |
1.13 |
0.12 |
3.74e-14 |
| OCDs |
1.45 |
1.23 |
1.67 |
0.11 |
5.39e-37 |
| Psychotic and bipolar disorder |
0.74 |
0.11 |
1.36 |
0.32 |
0.02 |
| Only psychotic disorder |
0.51 |
-0.03 |
1.05 |
0.27 |
0.06 |
| Only bipolar disorder |
0.65 |
0.31 |
0.98 |
0.17 |
1.82e-04 |
| PTSD |
1.58 |
1.38 |
1.79 |
0.11 |
1.17e-50 |
| ASD |
1.31 |
0.90 |
1.71 |
0.21 |
3.02e-10 |
| ADHD |
0.46 |
-0.08 |
0.99 |
0.27 |
0.09 |
| Personality disorder |
1.82 |
1.52 |
2.11 |
0.15 |
2.67e-33 |
| Female |
0.94 |
0.80 |
1.07 |
0.07 |
2.39e-42 |
| Non-binary/Self-defined |
0.68 |
0.14 |
1.22 |
0.28 |
0.01 |
| age_category_collapsed_reordered16-18 |
3.33 |
2.97 |
3.68 |
0.18 |
1.18e-75 |
| 19-25 years |
1.61 |
1.37 |
1.86 |
0.13 |
1.95e-37 |
| 36-45 years |
-0.64 |
-0.85 |
-0.44 |
0.11 |
1.14e-09 |
| 46-55 years |
-1.15 |
-1.34 |
-0.96 |
0.10 |
1.07e-31 |
| 56-65 years |
-2.02 |
-2.21 |
-1.83 |
0.10 |
4.70e-93 |
| 66-70 years |
-2.98 |
-3.23 |
-2.73 |
0.13 |
6.61e-121 |
| 71-75 years |
-3.21 |
-3.49 |
-2.93 |
0.14 |
4.74e-108 |
| 76+ years |
-3.09 |
-3.51 |
-2.66 |
0.22 |
1.77e-46 |
| Mixed or multiple ethnic origins |
0.09 |
-0.34 |
0.52 |
0.22 |
0.67 |
| Asian or Asian British |
0.15 |
-0.36 |
0.67 |
0.26 |
0.56 |
| African or African British |
-0.35 |
-1.28 |
0.59 |
0.48 |
0.47 |
| Other ethnicity |
0.78 |
0.02 |
1.53 |
0.38 |
0.04 |
| Key worker |
-0.35 |
-0.47 |
-0.22 |
0.06 |
3.75e-08 |
| Time difference: Lockdown to baseline |
-0.25 |
-0.27 |
-0.22 |
0.01 |
2.58e-65 |
| 32679 |
0.21 |
0.21 |
1485.53 |
0.00e+00 |
6 |
Model 2a: Disorder hierarchical, Adjusted with Age^2
| Intercept |
1.68 |
1.38 |
1.99 |
0.15 |
1.35e-27 |
| Anxiety disorders |
2.79 |
2.49 |
3.10 |
0.16 |
7.42e-72 |
| Eating disorders |
2.19 |
1.26 |
3.11 |
0.47 |
3.36e-06 |
| OCDs |
4.45 |
3.65 |
5.24 |
0.41 |
7.43e-28 |
| PTSD |
4.13 |
3.27 |
4.98 |
0.44 |
3.62e-21 |
| Depressive disorders |
4.67 |
4.51 |
4.82 |
0.08 |
0.00e+00 |
| Bipolar disorders |
6.05 |
5.72 |
6.38 |
0.17 |
2.09e-269 |
| Female |
0.72 |
0.57 |
0.87 |
0.08 |
8.83e-22 |
| Non-binary/Self-defined |
1.45 |
0.86 |
2.03 |
0.30 |
1.49e-06 |
| Age |
-252.22 |
-263.35 |
-241.08 |
5.68 |
0.00e+00 |
| Age^2 |
28.67 |
18.60 |
38.73 |
5.14 |
2.40e-08 |
| Mixed or multiple ethnic origins |
-0.02 |
-0.50 |
0.46 |
0.25 |
0.94 |
| Asian or Asian British |
-0.09 |
-0.74 |
0.55 |
0.33 |
0.78 |
| African or African British |
0.07 |
-0.98 |
1.12 |
0.54 |
0.90 |
| Other ethnicity |
1.23 |
0.37 |
2.10 |
0.44 |
0.005 |
| Time difference: Lockdown to baseline |
0.06 |
0.02 |
0.09 |
0.02 |
0.003 |
| 25356 |
0.26 |
0.26 |
1506.65 |
0.00e+00 |
6 |
Model 2b: Disorder hierarchical, Adjusted with Age^2
| Intercept |
1.88 |
1.58 |
2.17 |
0.15 |
3.06e-35 |
| Depressive and anxiety disorder |
4.90 |
4.74 |
5.06 |
0.08 |
0.00e+00 |
| Only depressive disorder |
1.98 |
1.77 |
2.18 |
0.10 |
1.43e-78 |
| Only anxiety disorder |
3.02 |
2.75 |
3.29 |
0.14 |
3.45e-104 |
| Eating disorders |
1.09 |
0.84 |
1.34 |
0.13 |
2.26e-17 |
| OCDs |
1.38 |
1.13 |
1.62 |
0.12 |
8.67e-29 |
| Psychotic and bipolar disorder |
0.44 |
-0.27 |
1.15 |
0.36 |
0.23 |
| Only psychotic disorder |
0.48 |
-0.10 |
1.06 |
0.30 |
0.10 |
| Only bipolar disorder |
0.64 |
0.29 |
0.99 |
0.18 |
3.50e-04 |
| PTSD |
1.69 |
1.47 |
1.92 |
0.11 |
3.99e-49 |
| ASD |
1.24 |
0.78 |
1.71 |
0.24 |
1.45e-07 |
| ADHD |
0.25 |
-0.37 |
0.87 |
0.32 |
0.43 |
| Personality disorder |
1.75 |
1.43 |
2.06 |
0.16 |
4.75e-27 |
| Female |
0.60 |
0.45 |
0.74 |
0.07 |
3.86e-16 |
| Non-binary/Self-defined |
0.54 |
-0.03 |
1.12 |
0.30 |
0.07 |
| Age |
-213.75 |
-225.08 |
-202.42 |
5.78 |
2.54e-290 |
| Age^2 |
19.85 |
9.76 |
29.94 |
5.15 |
1.15e-04 |
| Mixed or multiple ethnic origins |
0.00 |
-0.47 |
0.48 |
0.24 |
0.99 |
| Asian or Asian British |
0.34 |
-0.28 |
0.95 |
0.31 |
0.28 |
| African or African British |
-0.07 |
-1.08 |
0.93 |
0.51 |
0.89 |
| Other ethnicity |
1.08 |
0.21 |
1.95 |
0.44 |
0.01 |
| Key worker |
-0.35 |
-0.49 |
-0.22 |
0.07 |
2.62e-07 |
| Time difference: Lockdown to baseline |
0.05 |
0.02 |
0.09 |
0.02 |
0.004 |
| 25356 |
0.26 |
0.26 |
1506.65 |
0.00e+00 |
6 |
GAD prepan
Regression: Change scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
-1.16 |
-2.08 |
-0.23 |
0.47 |
0.01 |
| Anxiety disorders |
0.20 |
-0.83 |
1.22 |
0.52 |
0.71 |
| Eating disorders |
-0.55 |
-2.53 |
1.42 |
1.01 |
0.58 |
| OCDs |
0.08 |
-1.30 |
1.45 |
0.70 |
0.91 |
| PTSD |
-0.04 |
-1.62 |
1.54 |
0.80 |
0.96 |
| Depressive disorders |
0.90 |
-0.03 |
1.84 |
0.48 |
0.06 |
| Bipolar disorders |
0.82 |
-0.18 |
1.82 |
0.51 |
0.11 |
| 12006 |
0.00 |
0.00 |
3.23 |
0.004 |
6 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
-0.83 |
-1.51 |
-0.16 |
0.34 |
0.02 |
| Depressive and anxiety disorder |
0.45 |
-0.24 |
1.13 |
0.35 |
0.20 |
| Only depressive disorder |
0.98 |
0.24 |
1.72 |
0.38 |
0.009 |
| Only anxiety disorder |
-0.24 |
-1.01 |
0.53 |
0.40 |
0.54 |
| Eating disorders |
0.18 |
-0.15 |
0.51 |
0.17 |
0.29 |
| OCDs |
-0.26 |
-0.57 |
0.05 |
0.16 |
0.11 |
| Psychotic and bipolar disorder |
-0.51 |
-1.42 |
0.39 |
0.46 |
0.27 |
| Only psychotic disorder |
0.76 |
0.00 |
1.52 |
0.39 |
0.05 |
| Only bipolar disorder |
0.20 |
-0.26 |
0.65 |
0.23 |
0.40 |
| PTSD |
0.14 |
-0.16 |
0.43 |
0.15 |
0.36 |
| ASD |
0.16 |
-0.44 |
0.76 |
0.31 |
0.61 |
| ADHD |
-0.74 |
-1.56 |
0.09 |
0.42 |
0.08 |
| Personality disorder |
-0.16 |
-0.57 |
0.24 |
0.21 |
0.43 |
| 12006 |
0.00 |
0.00 |
3.23 |
0.004 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-1.41 |
-2.49 |
-0.34 |
0.55 |
0.01 |
| Anxiety disorders |
0.13 |
-0.90 |
1.15 |
0.52 |
0.80 |
| Eating disorders |
-0.70 |
-2.68 |
1.27 |
1.01 |
0.49 |
| OCDs |
-0.02 |
-1.40 |
1.35 |
0.70 |
0.97 |
| PTSD |
-0.19 |
-1.78 |
1.39 |
0.81 |
0.81 |
| Depressive disorders |
0.79 |
-0.14 |
1.73 |
0.48 |
0.10 |
| Bipolar disorders |
0.77 |
-0.23 |
1.77 |
0.51 |
0.13 |
| Female |
0.45 |
0.19 |
0.72 |
0.13 |
6.41e-04 |
| Non-binary/Self-defined |
0.48 |
-0.28 |
1.24 |
0.39 |
0.21 |
| age_category_collapsed_reordered16-18 |
-0.59 |
-1.24 |
0.06 |
0.33 |
0.08 |
| 19-25 years |
0.05 |
-0.30 |
0.40 |
0.18 |
0.77 |
| 36-45 years |
0.19 |
-0.11 |
0.50 |
0.15 |
0.21 |
| 46-55 years |
-0.01 |
-0.30 |
0.29 |
0.15 |
0.95 |
| 56-65 years |
0.14 |
-0.19 |
0.47 |
0.17 |
0.41 |
| 66-70 years |
-0.25 |
-0.83 |
0.32 |
0.29 |
0.39 |
| 71-75 years |
-0.32 |
-1.07 |
0.44 |
0.39 |
0.41 |
| 76+ years |
0.36 |
-1.04 |
1.77 |
0.72 |
0.61 |
| Mixed or multiple ethnic origins |
0.25 |
-0.43 |
0.93 |
0.35 |
0.48 |
| Asian or Asian British |
-0.35 |
-1.47 |
0.77 |
0.57 |
0.54 |
| African or African British |
-1.32 |
-3.12 |
0.47 |
0.92 |
0.15 |
| Other ethnicity |
0.07 |
-0.96 |
1.09 |
0.52 |
0.90 |
| Time difference: Lockdown to baseline |
-0.01 |
-0.07 |
0.05 |
0.03 |
0.82 |
| 12006 |
0.00 |
0.00 |
3.23 |
0.004 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 1b + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-1.18 |
-2.07 |
-0.29 |
0.46 |
0.010 |
| Depressive and anxiety disorder |
0.38 |
-0.31 |
1.07 |
0.35 |
0.28 |
| Only depressive disorder |
0.92 |
0.17 |
1.67 |
0.38 |
0.02 |
| Only anxiety disorder |
-0.29 |
-1.07 |
0.49 |
0.40 |
0.46 |
| Eating disorders |
0.14 |
-0.20 |
0.47 |
0.17 |
0.42 |
| OCDs |
-0.26 |
-0.58 |
0.05 |
0.16 |
0.10 |
| Psychotic and bipolar disorder |
-0.39 |
-1.30 |
0.52 |
0.47 |
0.40 |
| Only psychotic disorder |
0.79 |
0.02 |
1.55 |
0.39 |
0.04 |
| Only bipolar disorder |
0.29 |
-0.17 |
0.75 |
0.23 |
0.21 |
| PTSD |
0.11 |
-0.18 |
0.41 |
0.15 |
0.46 |
| ASD |
0.25 |
-0.36 |
0.87 |
0.31 |
0.41 |
| ADHD |
-0.72 |
-1.55 |
0.10 |
0.42 |
0.09 |
| Personality disorder |
-0.19 |
-0.60 |
0.22 |
0.21 |
0.36 |
| Female |
0.46 |
0.18 |
0.74 |
0.14 |
0.001 |
| Non-binary/Self-defined |
0.46 |
-0.33 |
1.25 |
0.40 |
0.26 |
| age_category_collapsed_reordered16-18 |
-0.49 |
-1.16 |
0.17 |
0.34 |
0.14 |
| 19-25 years |
0.04 |
-0.32 |
0.41 |
0.18 |
0.81 |
| 36-45 years |
0.12 |
-0.20 |
0.43 |
0.16 |
0.47 |
| 46-55 years |
-0.09 |
-0.40 |
0.22 |
0.16 |
0.55 |
| 56-65 years |
0.09 |
-0.26 |
0.44 |
0.18 |
0.63 |
| 66-70 years |
-0.33 |
-0.95 |
0.28 |
0.31 |
0.29 |
| 71-75 years |
-0.30 |
-1.11 |
0.51 |
0.41 |
0.46 |
| 76+ years |
0.38 |
-1.19 |
1.94 |
0.80 |
0.64 |
| Mixed or multiple ethnic origins |
0.32 |
-0.40 |
1.04 |
0.37 |
0.39 |
| Asian or Asian British |
-0.18 |
-1.35 |
0.98 |
0.60 |
0.76 |
| African or African British |
-1.66 |
-3.52 |
0.20 |
0.95 |
0.08 |
| Other ethnicity |
0.06 |
-1.03 |
1.14 |
0.55 |
0.92 |
| Key worker |
0.17 |
-0.05 |
0.39 |
0.11 |
0.12 |
| Time difference: Lockdown to baseline |
-0.01 |
-0.07 |
0.06 |
0.03 |
0.86 |
| 12006 |
0.00 |
0.00 |
3.23 |
0.004 |
6 |
Model 2a: Disorder hierarchical, Adjusted with Age^2
Model 0a + Gender_collapsed + age^2+ Ethnicity_collapsed + Time registration and baseline
| Intercept |
-1.38 |
-2.44 |
-0.32 |
0.54 |
0.01 |
| Anxiety disorders |
0.14 |
-0.89 |
1.16 |
0.52 |
0.80 |
| Eating disorders |
-0.69 |
-2.67 |
1.28 |
1.01 |
0.49 |
| OCDs |
-0.01 |
-1.39 |
1.36 |
0.70 |
0.98 |
| PTSD |
-0.16 |
-1.74 |
1.43 |
0.81 |
0.85 |
| Depressive disorders |
0.81 |
-0.13 |
1.74 |
0.48 |
0.09 |
| Bipolar disorders |
0.78 |
-0.22 |
1.78 |
0.51 |
0.13 |
| Female |
0.46 |
0.19 |
0.72 |
0.13 |
6.30e-04 |
| Non-binary/Self-defined |
0.49 |
-0.28 |
1.25 |
0.39 |
0.21 |
| Age |
0.97 |
-10.17 |
12.12 |
5.69 |
0.86 |
| Age^2 |
-10.43 |
-21.32 |
0.47 |
5.56 |
0.06 |
| Mixed or multiple ethnic origins |
0.25 |
-0.43 |
0.93 |
0.35 |
0.47 |
| Asian or Asian British |
-0.35 |
-1.47 |
0.77 |
0.57 |
0.54 |
| African or African British |
-1.32 |
-3.12 |
0.47 |
0.92 |
0.15 |
| Other ethnicity |
0.06 |
-0.97 |
1.08 |
0.52 |
0.91 |
| Time difference: Lockdown to baseline |
-0.01 |
-0.07 |
0.05 |
0.03 |
0.78 |
| 12006 |
0.00 |
0.00 |
3.23 |
0.004 |
6 |
Model 2b: Overlapping disorders, Adjusted with Age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-1.20 |
-2.06 |
-0.33 |
0.44 |
0.007 |
| Depressive and anxiety disorder |
0.40 |
-0.28 |
1.09 |
0.35 |
0.25 |
| Only depressive disorder |
0.95 |
0.20 |
1.69 |
0.38 |
0.01 |
| Only anxiety disorder |
-0.27 |
-1.05 |
0.51 |
0.40 |
0.49 |
| Eating disorders |
0.13 |
-0.20 |
0.47 |
0.17 |
0.43 |
| OCDs |
-0.26 |
-0.58 |
0.05 |
0.16 |
0.10 |
| Psychotic and bipolar disorder |
-0.40 |
-1.32 |
0.51 |
0.47 |
0.39 |
| Only psychotic disorder |
0.79 |
0.03 |
1.55 |
0.39 |
0.04 |
| Only bipolar disorder |
0.28 |
-0.17 |
0.74 |
0.23 |
0.22 |
| PTSD |
0.10 |
-0.19 |
0.40 |
0.15 |
0.50 |
| ASD |
0.24 |
-0.37 |
0.85 |
0.31 |
0.44 |
| ADHD |
-0.72 |
-1.55 |
0.10 |
0.42 |
0.09 |
| Personality disorder |
-0.18 |
-0.59 |
0.23 |
0.21 |
0.38 |
| Female |
0.46 |
0.18 |
0.74 |
0.14 |
0.001 |
| Non-binary/Self-defined |
0.46 |
-0.33 |
1.25 |
0.40 |
0.25 |
| Age |
-2.35 |
-14.24 |
9.53 |
6.06 |
0.70 |
| Age^2 |
-8.66 |
-20.49 |
3.17 |
6.04 |
0.15 |
| Mixed or multiple ethnic origins |
0.32 |
-0.40 |
1.04 |
0.37 |
0.38 |
| Asian or Asian British |
-0.19 |
-1.36 |
0.98 |
0.60 |
0.75 |
| African or African British |
-1.66 |
-3.52 |
0.20 |
0.95 |
0.08 |
| Other ethnicity |
0.05 |
-1.03 |
1.13 |
0.55 |
0.93 |
| Key worker |
0.16 |
-0.06 |
0.38 |
0.11 |
0.15 |
| Time difference: Lockdown to baseline |
-0.01 |
-0.07 |
0.06 |
0.03 |
0.82 |
| 12006 |
0.00 |
0.00 |
3.23 |
0.004 |
6 |
Regression: Absolute scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
2.21 |
1.40 |
3.03 |
0.42 |
1.16e-07 |
| gad.sum_score_prepan |
0.55 |
0.54 |
0.57 |
0.01 |
0.00e+00 |
| Anxiety disorders |
0.59 |
-0.30 |
1.49 |
0.46 |
0.19 |
| Eating disorders |
0.60 |
-1.12 |
2.33 |
0.88 |
0.49 |
| OCDs |
1.49 |
0.29 |
2.69 |
0.61 |
0.02 |
| PTSD |
1.06 |
-0.32 |
2.43 |
0.70 |
0.13 |
| Depressive disorders |
1.43 |
0.61 |
2.24 |
0.42 |
6.08e-04 |
| Bipolar disorders |
1.73 |
0.86 |
2.61 |
0.45 |
1.03e-04 |
| 12006 |
0.32 |
0.32 |
823.32 |
0.00e+00 |
7 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
2.98 |
2.38 |
3.58 |
0.30 |
1.34e-22 |
| gad.sum_score_prepan |
0.52 |
0.50 |
0.53 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
0.83 |
0.23 |
1.42 |
0.30 |
0.006 |
| Only depressive disorder |
-0.24 |
-0.88 |
0.40 |
0.33 |
0.47 |
| Only anxiety disorder |
0.11 |
-0.56 |
0.78 |
0.34 |
0.76 |
| Eating disorders |
0.73 |
0.44 |
1.02 |
0.15 |
6.17e-07 |
| OCDs |
0.61 |
0.34 |
0.88 |
0.14 |
1.08e-05 |
| Psychotic and bipolar disorder |
-0.53 |
-1.31 |
0.26 |
0.40 |
0.19 |
| Only psychotic disorder |
0.39 |
-0.27 |
1.05 |
0.34 |
0.24 |
| Only bipolar disorder |
0.17 |
-0.23 |
0.56 |
0.20 |
0.41 |
| PTSD |
0.75 |
0.50 |
1.01 |
0.13 |
5.96e-09 |
| ASD |
0.90 |
0.38 |
1.42 |
0.27 |
7.08e-04 |
| ADHD |
-0.13 |
-0.84 |
0.59 |
0.36 |
0.73 |
| Personality disorder |
0.92 |
0.56 |
1.27 |
0.18 |
3.95e-07 |
| 12028 |
0.00 |
0.00 |
8.99 |
7.92e-10 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.30 |
1.35 |
3.25 |
0.48 |
1.99e-06 |
| gad.sum_score_prepan |
0.52 |
0.51 |
0.54 |
0.01 |
0.00e+00 |
| Anxiety disorders |
0.56 |
-0.33 |
1.46 |
0.46 |
0.21 |
| Eating disorders |
0.48 |
-1.23 |
2.19 |
0.87 |
0.58 |
| OCDs |
1.26 |
0.07 |
2.46 |
0.61 |
0.04 |
| PTSD |
1.32 |
-0.06 |
2.69 |
0.70 |
0.06 |
| Depressive disorders |
1.53 |
0.72 |
2.35 |
0.42 |
2.34e-04 |
| Bipolar disorders |
1.97 |
1.10 |
2.85 |
0.45 |
1.01e-05 |
| Female |
0.55 |
0.32 |
0.77 |
0.12 |
2.33e-06 |
| Non-binary/Self-defined |
0.86 |
0.20 |
1.51 |
0.34 |
0.01 |
| age_category_collapsed_reordered16-18 |
0.92 |
0.35 |
1.49 |
0.29 |
0.002 |
| 19-25 years |
0.72 |
0.42 |
1.03 |
0.15 |
3.08e-06 |
| 36-45 years |
-0.15 |
-0.42 |
0.11 |
0.13 |
0.25 |
| 46-55 years |
-0.51 |
-0.77 |
-0.26 |
0.13 |
8.84e-05 |
| 56-65 years |
-1.03 |
-1.32 |
-0.74 |
0.15 |
3.46e-12 |
| 66-70 years |
-2.00 |
-2.51 |
-1.49 |
0.26 |
1.22e-14 |
| 71-75 years |
-2.33 |
-2.99 |
-1.67 |
0.34 |
5.72e-12 |
| 76+ years |
-2.01 |
-3.23 |
-0.79 |
0.62 |
0.001 |
| Mixed or multiple ethnic origins |
0.03 |
-0.57 |
0.62 |
0.30 |
0.93 |
| Asian or Asian British |
-0.27 |
-1.24 |
0.71 |
0.50 |
0.59 |
| African or African British |
-0.43 |
-1.98 |
1.12 |
0.79 |
0.59 |
| Other ethnicity |
0.40 |
-0.49 |
1.29 |
0.45 |
0.38 |
| Key worker |
-0.34 |
-0.52 |
-0.16 |
0.09 |
1.96e-04 |
| Time difference: Lockdown to baseline |
0.01 |
-0.04 |
0.06 |
0.03 |
0.70 |
| 12028 |
0.00 |
0.00 |
8.99 |
7.92e-10 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
3.07 |
2.30 |
3.85 |
0.40 |
1.02e-14 |
| gad.sum_score_prepan |
0.49 |
0.48 |
0.51 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
0.92 |
0.33 |
1.51 |
0.30 |
0.002 |
| Only depressive disorder |
0.01 |
-0.63 |
0.65 |
0.33 |
0.97 |
| Only anxiety disorder |
0.07 |
-0.60 |
0.74 |
0.34 |
0.84 |
| Eating disorders |
0.61 |
0.32 |
0.89 |
0.15 |
3.68e-05 |
| OCDs |
0.53 |
0.26 |
0.80 |
0.14 |
1.23e-04 |
| Psychotic and bipolar disorder |
-0.26 |
-1.04 |
0.52 |
0.40 |
0.52 |
| Only psychotic disorder |
0.45 |
-0.20 |
1.10 |
0.33 |
0.18 |
| Only bipolar disorder |
0.32 |
-0.07 |
0.71 |
0.20 |
0.11 |
| PTSD |
0.82 |
0.56 |
1.07 |
0.13 |
2.73e-10 |
| ASD |
0.71 |
0.18 |
1.23 |
0.27 |
0.009 |
| ADHD |
-0.22 |
-0.93 |
0.49 |
0.36 |
0.55 |
| Personality disorder |
0.79 |
0.44 |
1.15 |
0.18 |
1.09e-05 |
| Female |
0.40 |
0.16 |
0.64 |
0.12 |
9.70e-04 |
| Non-binary/Self-defined |
0.41 |
-0.27 |
1.09 |
0.35 |
0.23 |
| age_category_collapsed_reordered16-18 |
1.04 |
0.47 |
1.60 |
0.29 |
3.68e-04 |
| 19-25 years |
0.75 |
0.44 |
1.06 |
0.16 |
2.44e-06 |
| 36-45 years |
-0.15 |
-0.42 |
0.12 |
0.14 |
0.29 |
| 46-55 years |
-0.43 |
-0.70 |
-0.17 |
0.14 |
0.001 |
| 56-65 years |
-0.87 |
-1.17 |
-0.56 |
0.15 |
1.82e-08 |
| 66-70 years |
-1.85 |
-2.37 |
-1.32 |
0.27 |
7.69e-12 |
| 71-75 years |
-2.04 |
-2.73 |
-1.34 |
0.36 |
1.01e-08 |
| 76+ years |
-1.53 |
-2.87 |
-0.18 |
0.69 |
0.03 |
| Mixed or multiple ethnic origins |
0.06 |
-0.56 |
0.68 |
0.32 |
0.86 |
| Asian or Asian British |
-0.03 |
-1.03 |
0.97 |
0.51 |
0.95 |
| African or African British |
-0.68 |
-2.27 |
0.92 |
0.81 |
0.41 |
| Other ethnicity |
0.46 |
-0.47 |
1.39 |
0.47 |
0.33 |
| Key worker |
-0.22 |
-0.41 |
-0.04 |
0.09 |
0.02 |
| Time difference: Lockdown to baseline |
0.00 |
-0.05 |
0.06 |
0.03 |
0.89 |
| 12028 |
0.00 |
0.00 |
8.99 |
7.92e-10 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.04 |
1.11 |
2.97 |
0.47 |
1.80e-05 |
| gad.sum_score_prepan |
0.52 |
0.51 |
0.54 |
0.01 |
0.00e+00 |
| Anxiety disorders |
0.54 |
-0.35 |
1.44 |
0.46 |
0.23 |
| Eating disorders |
0.47 |
-1.24 |
2.18 |
0.87 |
0.59 |
| OCDs |
1.27 |
0.08 |
2.47 |
0.61 |
0.04 |
| PTSD |
1.29 |
-0.09 |
2.66 |
0.70 |
0.07 |
| Depressive disorders |
1.50 |
0.69 |
2.32 |
0.42 |
3.06e-04 |
| Bipolar disorders |
1.94 |
1.06 |
2.81 |
0.45 |
1.42e-05 |
| Female |
0.53 |
0.30 |
0.76 |
0.12 |
4.52e-06 |
| Non-binary/Self-defined |
0.85 |
0.19 |
1.50 |
0.34 |
0.01 |
| Age |
-74.57 |
-84.53 |
-64.61 |
5.08 |
2.57e-48 |
| Age^2 |
-10.41 |
-20.12 |
-0.71 |
4.95 |
0.04 |
| Mixed or multiple ethnic origins |
0.00 |
-0.59 |
0.60 |
0.30 |
0.99 |
| Asian or Asian British |
-0.26 |
-1.23 |
0.72 |
0.50 |
0.60 |
| African or African British |
-0.43 |
-1.98 |
1.12 |
0.79 |
0.59 |
| Other ethnicity |
0.41 |
-0.48 |
1.30 |
0.45 |
0.37 |
| Key worker |
-0.35 |
-0.53 |
-0.17 |
0.09 |
1.08e-04 |
| Time difference: Lockdown to baseline |
0.01 |
-0.04 |
0.06 |
0.03 |
0.67 |
| 12028 |
0.00 |
0.00 |
8.99 |
7.92e-10 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.87 |
2.12 |
3.62 |
0.38 |
6.88e-14 |
| gad.sum_score_prepan |
0.49 |
0.48 |
0.51 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
0.88 |
0.29 |
1.47 |
0.30 |
0.004 |
| Only depressive disorder |
-0.01 |
-0.65 |
0.63 |
0.33 |
0.99 |
| Only anxiety disorder |
0.04 |
-0.63 |
0.71 |
0.34 |
0.91 |
| Eating disorders |
0.61 |
0.32 |
0.90 |
0.15 |
3.18e-05 |
| OCDs |
0.52 |
0.25 |
0.79 |
0.14 |
1.45e-04 |
| Psychotic and bipolar disorder |
-0.24 |
-1.03 |
0.54 |
0.40 |
0.54 |
| Only psychotic disorder |
0.47 |
-0.18 |
1.12 |
0.33 |
0.16 |
| Only bipolar disorder |
0.32 |
-0.07 |
0.71 |
0.20 |
0.11 |
| PTSD |
0.83 |
0.57 |
1.08 |
0.13 |
1.83e-10 |
| ASD |
0.73 |
0.20 |
1.25 |
0.27 |
0.007 |
| ADHD |
-0.25 |
-0.96 |
0.46 |
0.36 |
0.49 |
| Personality disorder |
0.75 |
0.40 |
1.10 |
0.18 |
3.18e-05 |
| Female |
0.39 |
0.15 |
0.63 |
0.12 |
0.001 |
| Non-binary/Self-defined |
0.40 |
-0.28 |
1.08 |
0.35 |
0.25 |
| Age |
-68.91 |
-79.32 |
-58.50 |
5.31 |
3.00e-38 |
| Age^2 |
-6.01 |
-16.16 |
4.15 |
5.18 |
0.25 |
| Mixed or multiple ethnic origins |
0.04 |
-0.58 |
0.66 |
0.32 |
0.90 |
| Asian or Asian British |
-0.03 |
-1.03 |
0.97 |
0.51 |
0.95 |
| African or African British |
-0.68 |
-2.28 |
0.92 |
0.81 |
0.40 |
| Other ethnicity |
0.46 |
-0.47 |
1.38 |
0.47 |
0.34 |
| Key worker |
-0.23 |
-0.42 |
-0.05 |
0.09 |
0.01 |
| Time difference: Lockdown to baseline |
0.01 |
-0.05 |
0.06 |
0.03 |
0.86 |
| 12028 |
0.00 |
0.00 |
8.99 |
7.92e-10 |
6 |
GAD prepan: sensitivity
Regression: Absolute scores
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline #### Subset of participants 3 months prior to pandemic
| Intercept |
2.34 |
-0.05 |
4.72 |
1.21 |
0.05 |
| gad.sum_score_prepan |
0.54 |
0.49 |
0.60 |
0.03 |
1.22e-63 |
| Depressive and anxiety disorder |
0.73 |
-0.92 |
2.38 |
0.84 |
0.39 |
| Only depressive disorder |
-0.27 |
-2.04 |
1.51 |
0.90 |
0.77 |
| Only anxiety disorder |
0.11 |
-1.87 |
2.08 |
1.01 |
0.92 |
| Eating disorders |
0.88 |
-0.16 |
1.92 |
0.53 |
0.10 |
| OCDs |
0.03 |
-1.02 |
1.08 |
0.54 |
0.96 |
| Psychotic and bipolar disorder |
-0.81 |
-3.33 |
1.71 |
1.28 |
0.53 |
| Only psychotic disorder |
0.37 |
-2.23 |
2.96 |
1.32 |
0.78 |
| Only bipolar disorder |
-0.53 |
-2.17 |
1.11 |
0.84 |
0.53 |
| PTSD |
2.02 |
1.06 |
2.98 |
0.49 |
3.84e-05 |
| ASD |
1.10 |
-0.73 |
2.92 |
0.93 |
0.24 |
| ADHD |
-0.19 |
-2.74 |
2.36 |
1.30 |
0.88 |
| Personality disorder |
-0.51 |
-1.83 |
0.80 |
0.67 |
0.44 |
| Female |
0.64 |
-0.22 |
1.49 |
0.44 |
0.14 |
| Non-binary/Self-defined |
-0.79 |
-3.92 |
2.33 |
1.59 |
0.62 |
| age_category_collapsed_reordered16-18 |
1.36 |
-0.51 |
3.22 |
0.95 |
0.15 |
| 19-25 years |
0.83 |
-0.44 |
2.10 |
0.64 |
0.20 |
| 36-45 years |
-0.05 |
-1.11 |
1.01 |
0.54 |
0.93 |
| 46-55 years |
-0.36 |
-1.42 |
0.70 |
0.54 |
0.50 |
| 56-65 years |
-0.27 |
-1.38 |
0.84 |
0.56 |
0.63 |
| 66-70 years |
-1.36 |
-3.33 |
0.61 |
1.00 |
0.17 |
| 71-75 years |
-0.92 |
-3.73 |
1.88 |
1.43 |
0.52 |
| 76+ years |
0.39 |
-3.07 |
3.86 |
1.76 |
0.82 |
| Mixed or multiple ethnic origins |
-0.49 |
-2.75 |
1.78 |
1.15 |
0.67 |
| Asian or Asian British |
-0.18 |
-3.79 |
3.43 |
1.84 |
0.92 |
| African or African British |
-3.14 |
-7.41 |
1.13 |
2.18 |
0.15 |
| Other ethnicity |
0.61 |
-3.62 |
4.84 |
2.16 |
0.78 |
| Key worker |
0.25 |
-0.48 |
0.97 |
0.37 |
0.50 |
| Time difference: Lockdown to baseline |
-0.01 |
-0.18 |
0.16 |
0.09 |
0.89 |
| 831 |
0.01 |
0.00 |
1.47 |
0.18 |
6 |
Subset of participants 6 months prior to pandemic
| Intercept |
2.12 |
0.46 |
3.79 |
0.85 |
0.01 |
| gad.sum_score_prepan |
0.54 |
0.50 |
0.58 |
0.02 |
1.01e-128 |
| Depressive and anxiety disorder |
0.82 |
-0.26 |
1.90 |
0.55 |
0.14 |
| Only depressive disorder |
-0.20 |
-1.39 |
0.98 |
0.60 |
0.74 |
| Only anxiety disorder |
0.31 |
-0.99 |
1.62 |
0.66 |
0.64 |
| Eating disorders |
0.55 |
-0.20 |
1.30 |
0.38 |
0.15 |
| OCDs |
0.58 |
-0.12 |
1.28 |
0.36 |
0.11 |
| Psychotic and bipolar disorder |
-0.47 |
-2.50 |
1.56 |
1.03 |
0.65 |
| Only psychotic disorder |
0.47 |
-1.08 |
2.02 |
0.79 |
0.55 |
| Only bipolar disorder |
-0.10 |
-1.15 |
0.96 |
0.54 |
0.85 |
| PTSD |
1.73 |
1.07 |
2.40 |
0.34 |
4.05e-07 |
| ASD |
0.33 |
-1.04 |
1.69 |
0.70 |
0.64 |
| ADHD |
-0.61 |
-2.22 |
1.00 |
0.82 |
0.46 |
| Personality disorder |
0.51 |
-0.40 |
1.43 |
0.47 |
0.27 |
| Female |
0.58 |
-0.02 |
1.18 |
0.31 |
0.06 |
| Non-binary/Self-defined |
0.94 |
-0.98 |
2.86 |
0.98 |
0.34 |
| age_category_collapsed_reordered16-18 |
1.26 |
0.11 |
2.41 |
0.59 |
0.03 |
| 19-25 years |
0.90 |
0.02 |
1.78 |
0.45 |
0.04 |
| 36-45 years |
-0.28 |
-1.03 |
0.47 |
0.38 |
0.47 |
| 46-55 years |
-0.59 |
-1.33 |
0.15 |
0.38 |
0.12 |
| 56-65 years |
-0.46 |
-1.26 |
0.33 |
0.40 |
0.25 |
| 66-70 years |
-1.02 |
-2.36 |
0.31 |
0.68 |
0.13 |
| 71-75 years |
-1.42 |
-3.01 |
0.17 |
0.81 |
0.08 |
| 76+ years |
0.41 |
-2.05 |
2.87 |
1.25 |
0.74 |
| Mixed or multiple ethnic origins |
0.71 |
-0.84 |
2.27 |
0.79 |
0.37 |
| Asian or Asian British |
-0.71 |
-2.78 |
1.36 |
1.06 |
0.50 |
| African or African British |
-3.09 |
-6.58 |
0.40 |
1.78 |
0.08 |
| Other ethnicity |
-0.37 |
-2.84 |
2.10 |
1.26 |
0.77 |
| Key worker |
0.06 |
-0.43 |
0.56 |
0.25 |
0.80 |
| Time difference: Lockdown to baseline |
0.00 |
-0.14 |
0.13 |
0.07 |
0.95 |
| 1637 |
0.00 |
0.00 |
1.21 |
0.30 |
6 |
Subset of participants 9 months prior to pandemic
| Intercept |
2.70 |
1.39 |
4.00 |
0.67 |
5.16e-05 |
| gad.sum_score_prepan |
0.53 |
0.50 |
0.57 |
0.02 |
6.85e-209 |
| Depressive and anxiety disorder |
1.03 |
0.17 |
1.88 |
0.44 |
0.02 |
| Only depressive disorder |
0.22 |
-0.71 |
1.14 |
0.47 |
0.65 |
| Only anxiety disorder |
0.49 |
-0.54 |
1.53 |
0.53 |
0.35 |
| Eating disorders |
0.92 |
0.34 |
1.50 |
0.29 |
0.002 |
| OCDs |
0.57 |
0.03 |
1.11 |
0.28 |
0.04 |
| Psychotic and bipolar disorder |
-0.66 |
-2.16 |
0.85 |
0.77 |
0.39 |
| Only psychotic disorder |
0.74 |
-0.47 |
1.94 |
0.62 |
0.23 |
| Only bipolar disorder |
0.22 |
-0.59 |
1.02 |
0.41 |
0.60 |
| PTSD |
1.36 |
0.85 |
1.87 |
0.26 |
1.50e-07 |
| ASD |
0.07 |
-1.00 |
1.13 |
0.54 |
0.90 |
| ADHD |
-0.63 |
-1.94 |
0.68 |
0.67 |
0.35 |
| Personality disorder |
0.77 |
0.07 |
1.48 |
0.36 |
0.03 |
| Female |
0.42 |
-0.04 |
0.87 |
0.23 |
0.07 |
| Non-binary/Self-defined |
1.00 |
-0.42 |
2.41 |
0.72 |
0.17 |
| age_category_collapsed_reordered16-18 |
1.12 |
0.13 |
2.12 |
0.51 |
0.03 |
| 19-25 years |
0.48 |
-0.21 |
1.17 |
0.35 |
0.17 |
| 36-45 years |
-0.24 |
-0.81 |
0.34 |
0.29 |
0.42 |
| 46-55 years |
-0.53 |
-1.08 |
0.02 |
0.28 |
0.06 |
| 56-65 years |
-0.80 |
-1.39 |
-0.20 |
0.30 |
0.009 |
| 66-70 years |
-1.23 |
-2.21 |
-0.25 |
0.50 |
0.01 |
| 71-75 years |
-1.05 |
-2.23 |
0.14 |
0.60 |
0.08 |
| 76+ years |
-0.61 |
-2.65 |
1.43 |
1.04 |
0.56 |
| Mixed or multiple ethnic origins |
0.84 |
-0.47 |
2.15 |
0.67 |
0.21 |
| Asian or Asian British |
-0.16 |
-1.77 |
1.46 |
0.83 |
0.85 |
| African or African British |
-0.23 |
-2.97 |
2.51 |
1.40 |
0.87 |
| Other ethnicity |
0.04 |
-1.60 |
1.68 |
0.84 |
0.96 |
| Key worker |
-0.05 |
-0.43 |
0.32 |
0.19 |
0.78 |
| Time difference: Lockdown to baseline |
-0.06 |
-0.16 |
0.05 |
0.05 |
0.28 |
| 2715 |
0.01 |
0.00 |
2.97 |
0.007 |
6 |
GAD retro
Regression: Change scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
2.58 |
2.44 |
2.72 |
0.07 |
1.55e-271 |
| Anxiety disorders |
0.84 |
0.54 |
1.15 |
0.16 |
6.90e-08 |
| Eating disorders |
0.40 |
-0.52 |
1.31 |
0.47 |
0.40 |
| OCDs |
1.16 |
0.40 |
1.92 |
0.39 |
0.003 |
| PTSD |
1.37 |
0.63 |
2.10 |
0.38 |
2.69e-04 |
| Depressive disorders |
0.87 |
0.70 |
1.04 |
0.09 |
2.08e-24 |
| Bipolar disorders |
0.83 |
0.46 |
1.19 |
0.19 |
9.14e-06 |
| 19545 |
0.01 |
0.01 |
18.93 |
4.26e-22 |
6 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
2.58 |
2.45 |
2.71 |
0.07 |
2.17e-303 |
| Depressive and anxiety disorder |
0.85 |
0.68 |
1.03 |
0.09 |
4.94e-21 |
| Only depressive disorder |
0.25 |
0.01 |
0.48 |
0.12 |
0.04 |
| Only anxiety disorder |
0.86 |
0.58 |
1.15 |
0.14 |
2.26e-09 |
| Eating disorders |
0.49 |
0.22 |
0.76 |
0.14 |
4.28e-04 |
| OCDs |
0.05 |
-0.21 |
0.31 |
0.13 |
0.72 |
| Psychotic and bipolar disorder |
-0.20 |
-0.96 |
0.56 |
0.39 |
0.61 |
| Only psychotic disorder |
-0.28 |
-0.94 |
0.38 |
0.34 |
0.41 |
| Only bipolar disorder |
-0.21 |
-0.62 |
0.19 |
0.21 |
0.30 |
| PTSD |
0.41 |
0.17 |
0.66 |
0.12 |
8.72e-04 |
| ASD |
0.36 |
-0.12 |
0.83 |
0.24 |
0.14 |
| ADHD |
0.01 |
-0.63 |
0.64 |
0.32 |
0.99 |
| Personality disorder |
0.29 |
-0.06 |
0.64 |
0.18 |
0.11 |
| 19545 |
0.01 |
0.01 |
18.93 |
4.26e-22 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
4.19 |
3.83 |
4.55 |
0.18 |
1.28e-112 |
| Anxiety disorders |
0.55 |
0.23 |
0.87 |
0.16 |
7.12e-04 |
| Eating disorders |
0.00 |
-0.93 |
0.94 |
0.47 |
0.99 |
| OCDs |
0.57 |
-0.21 |
1.35 |
0.40 |
0.15 |
| PTSD |
1.11 |
0.35 |
1.86 |
0.39 |
0.004 |
| Depressive disorders |
0.62 |
0.43 |
0.80 |
0.09 |
5.33e-11 |
| Bipolar disorders |
0.61 |
0.24 |
0.99 |
0.19 |
0.001 |
| Female |
0.76 |
0.56 |
0.95 |
0.10 |
1.32e-14 |
| Non-binary/Self-defined |
-0.15 |
-0.80 |
0.49 |
0.33 |
0.64 |
| age_category_collapsed_reordered16-18 |
-0.43 |
-0.84 |
-0.01 |
0.21 |
0.04 |
| 19-25 years |
0.73 |
0.44 |
1.02 |
0.15 |
6.32e-07 |
| 36-45 years |
-0.50 |
-0.75 |
-0.25 |
0.13 |
8.62e-05 |
| 46-55 years |
-0.68 |
-0.91 |
-0.45 |
0.12 |
1.23e-08 |
| 56-65 years |
-0.88 |
-1.11 |
-0.64 |
0.12 |
4.16e-13 |
| 66-70 years |
-1.15 |
-1.50 |
-0.81 |
0.18 |
5.82e-11 |
| 71-75 years |
-1.60 |
-2.02 |
-1.18 |
0.22 |
1.39e-13 |
| 76+ years |
-1.89 |
-2.63 |
-1.16 |
0.38 |
4.66e-07 |
| Mixed or multiple ethnic origins |
-0.63 |
-1.16 |
-0.11 |
0.27 |
0.02 |
| Asian or Asian British |
-0.43 |
-1.13 |
0.27 |
0.36 |
0.23 |
| African or African British |
-0.83 |
-2.09 |
0.44 |
0.65 |
0.20 |
| Other ethnicity |
-0.08 |
-0.97 |
0.80 |
0.45 |
0.85 |
| Time difference: Lockdown to baseline |
-0.23 |
-0.26 |
-0.19 |
0.02 |
1.09e-35 |
| 19545 |
0.01 |
0.01 |
18.93 |
4.26e-22 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
3.94 |
3.57 |
4.31 |
0.19 |
2.33e-95 |
| Depressive and anxiety disorder |
0.65 |
0.45 |
0.84 |
0.10 |
5.79e-11 |
| Only depressive disorder |
0.25 |
0.00 |
0.51 |
0.13 |
0.05 |
| Only anxiety disorder |
0.63 |
0.33 |
0.93 |
0.15 |
3.24e-05 |
| Eating disorders |
0.28 |
0.01 |
0.56 |
0.14 |
0.04 |
| OCDs |
-0.09 |
-0.36 |
0.17 |
0.14 |
0.49 |
| Psychotic and bipolar disorder |
0.10 |
-0.67 |
0.86 |
0.39 |
0.80 |
| Only psychotic disorder |
-0.05 |
-0.71 |
0.62 |
0.34 |
0.89 |
| Only bipolar disorder |
-0.11 |
-0.52 |
0.30 |
0.21 |
0.60 |
| PTSD |
0.43 |
0.18 |
0.68 |
0.13 |
6.91e-04 |
| ASD |
0.36 |
-0.13 |
0.85 |
0.25 |
0.15 |
| ADHD |
-0.06 |
-0.70 |
0.58 |
0.33 |
0.85 |
| Personality disorder |
0.18 |
-0.18 |
0.53 |
0.18 |
0.33 |
| Female |
0.73 |
0.53 |
0.93 |
0.10 |
3.89e-13 |
| Non-binary/Self-defined |
-0.32 |
-0.98 |
0.34 |
0.34 |
0.35 |
| age_category_collapsed_reordered16-18 |
-0.20 |
-0.62 |
0.22 |
0.21 |
0.35 |
| 19-25 years |
0.74 |
0.45 |
1.03 |
0.15 |
7.34e-07 |
| 36-45 years |
-0.50 |
-0.75 |
-0.24 |
0.13 |
1.23e-04 |
| 46-55 years |
-0.67 |
-0.91 |
-0.43 |
0.12 |
4.76e-08 |
| 56-65 years |
-0.72 |
-0.97 |
-0.47 |
0.13 |
1.06e-08 |
| 66-70 years |
-0.87 |
-1.23 |
-0.51 |
0.18 |
2.39e-06 |
| 71-75 years |
-1.28 |
-1.72 |
-0.84 |
0.22 |
1.08e-08 |
| 76+ years |
-1.58 |
-2.33 |
-0.84 |
0.38 |
3.15e-05 |
| Mixed or multiple ethnic origins |
-0.57 |
-1.10 |
-0.04 |
0.27 |
0.04 |
| Asian or Asian British |
-0.22 |
-0.91 |
0.46 |
0.35 |
0.53 |
| African or African British |
-1.10 |
-2.36 |
0.17 |
0.65 |
0.09 |
| Other ethnicity |
0.08 |
-0.82 |
0.98 |
0.46 |
0.86 |
| Key worker |
0.31 |
0.15 |
0.47 |
0.08 |
1.21e-04 |
| Time difference: Lockdown to baseline |
-0.22 |
-0.26 |
-0.19 |
0.02 |
6.21e-34 |
| 19545 |
0.01 |
0.01 |
18.93 |
4.26e-22 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
1.97 |
1.54 |
2.39 |
0.22 |
1.63e-19 |
| Anxiety disorders |
0.53 |
0.12 |
0.94 |
0.21 |
0.01 |
| Eating disorders |
0.37 |
-0.79 |
1.53 |
0.59 |
0.53 |
| OCDs |
0.39 |
-0.63 |
1.40 |
0.52 |
0.45 |
| PTSD |
1.32 |
0.23 |
2.42 |
0.56 |
0.02 |
| Depressive disorders |
0.92 |
0.69 |
1.15 |
0.12 |
4.50e-15 |
| Bipolar disorders |
0.99 |
0.56 |
1.42 |
0.22 |
7.14e-06 |
| Female |
0.61 |
0.39 |
0.83 |
0.11 |
4.12e-08 |
| Non-binary/Self-defined |
-0.49 |
-1.21 |
0.22 |
0.37 |
0.18 |
| Age |
-96.47 |
-111.58 |
-81.36 |
7.71 |
1.00e-35 |
| Age^2 |
8.51 |
-5.53 |
22.55 |
7.16 |
0.23 |
| Mixed or multiple ethnic origins |
-0.69 |
-1.31 |
-0.08 |
0.31 |
0.03 |
| Asian or Asian British |
-0.20 |
-1.10 |
0.71 |
0.46 |
0.67 |
| African or African British |
-0.76 |
-2.25 |
0.72 |
0.76 |
0.32 |
| Other ethnicity |
0.07 |
-1.01 |
1.14 |
0.55 |
0.90 |
| Time difference: Lockdown to baseline |
-0.06 |
-0.11 |
-0.02 |
0.02 |
0.010 |
| 14004 |
0.01 |
0.01 |
29.70 |
1.42e-35 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
1.87 |
1.44 |
2.31 |
0.22 |
2.58e-17 |
| Depressive and anxiety disorder |
0.94 |
0.71 |
1.18 |
0.12 |
6.86e-15 |
| Only depressive disorder |
0.48 |
0.17 |
0.79 |
0.16 |
0.002 |
| Only anxiety disorder |
0.60 |
0.22 |
0.98 |
0.19 |
0.002 |
| Eating disorders |
0.26 |
-0.05 |
0.58 |
0.16 |
0.10 |
| OCDs |
-0.27 |
-0.57 |
0.03 |
0.15 |
0.08 |
| Psychotic and bipolar disorder |
0.33 |
-0.57 |
1.24 |
0.46 |
0.47 |
| Only psychotic disorder |
-0.06 |
-0.81 |
0.68 |
0.38 |
0.87 |
| Only bipolar disorder |
-0.11 |
-0.56 |
0.33 |
0.23 |
0.62 |
| PTSD |
0.58 |
0.30 |
0.86 |
0.14 |
5.59e-05 |
| ASD |
0.15 |
-0.44 |
0.73 |
0.30 |
0.62 |
| ADHD |
0.09 |
-0.70 |
0.88 |
0.40 |
0.82 |
| Personality disorder |
0.31 |
-0.09 |
0.71 |
0.20 |
0.13 |
| Female |
0.57 |
0.35 |
0.79 |
0.11 |
5.57e-07 |
| Non-binary/Self-defined |
-0.73 |
-1.47 |
0.01 |
0.38 |
0.05 |
| Age |
-82.49 |
-98.45 |
-66.52 |
8.14 |
5.15e-24 |
| Age^2 |
18.68 |
4.05 |
33.31 |
7.46 |
0.01 |
| Mixed or multiple ethnic origins |
-0.62 |
-1.24 |
0.01 |
0.32 |
0.05 |
| Asian or Asian British |
-0.10 |
-0.99 |
0.79 |
0.45 |
0.82 |
| African or African British |
-1.01 |
-2.51 |
0.49 |
0.77 |
0.19 |
| Other ethnicity |
0.11 |
-0.98 |
1.19 |
0.55 |
0.85 |
| Key worker |
0.33 |
0.15 |
0.51 |
0.09 |
4.48e-04 |
| Time difference: Lockdown to baseline |
-0.07 |
-0.12 |
-0.02 |
0.03 |
0.009 |
| 14004 |
0.01 |
0.01 |
29.70 |
1.42e-35 |
6 |
Regression: Absolute scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
1.38 |
1.31 |
1.46 |
0.04 |
1.10e-275 |
| gad.sum_score_retro |
0.77 |
0.76 |
0.78 |
0.01 |
0.00e+00 |
| Anxiety disorders |
2.13 |
1.93 |
2.34 |
0.11 |
9.92e-91 |
| Eating disorders |
1.88 |
1.22 |
2.54 |
0.34 |
2.07e-08 |
| OCDs |
2.84 |
2.31 |
3.38 |
0.27 |
2.25e-25 |
| PTSD |
2.67 |
2.15 |
3.18 |
0.26 |
3.62e-24 |
| Depressive disorders |
2.65 |
2.54 |
2.76 |
0.06 |
0.00e+00 |
| Bipolar disorders |
3.13 |
2.86 |
3.40 |
0.14 |
1.12e-115 |
| 30902 |
0.53 |
0.53 |
4928.90 |
0.00e+00 |
7 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
1.54 |
1.46 |
1.61 |
0.04 |
0.00e+00 |
| gad.sum_score_retro |
0.72 |
0.71 |
0.73 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
2.92 |
2.79 |
3.04 |
0.06 |
0.00e+00 |
| Only depressive disorder |
1.17 |
1.02 |
1.32 |
0.08 |
1.47e-54 |
| Only anxiety disorder |
2.24 |
2.05 |
2.43 |
0.10 |
5.26e-117 |
| Eating disorders |
0.79 |
0.59 |
0.98 |
0.10 |
8.05e-15 |
| OCDs |
0.59 |
0.40 |
0.79 |
0.10 |
1.16e-09 |
| Psychotic and bipolar disorder |
0.07 |
-0.47 |
0.61 |
0.28 |
0.80 |
| Only psychotic disorder |
-0.02 |
-0.49 |
0.45 |
0.24 |
0.93 |
| Only bipolar disorder |
0.14 |
-0.15 |
0.44 |
0.15 |
0.34 |
| PTSD |
0.72 |
0.54 |
0.89 |
0.09 |
1.42e-15 |
| ASD |
0.89 |
0.55 |
1.24 |
0.18 |
4.01e-07 |
| ADHD |
0.36 |
-0.10 |
0.81 |
0.23 |
0.12 |
| Personality disorder |
0.68 |
0.43 |
0.93 |
0.13 |
1.36e-07 |
| 30973 |
0.25 |
0.25 |
1678.24 |
0.00e+00 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
3.72 |
3.47 |
3.97 |
0.13 |
1.43e-189 |
| gad.sum_score_retro |
0.70 |
0.69 |
0.71 |
0.01 |
0.00e+00 |
| Anxiety disorders |
1.63 |
1.41 |
1.85 |
0.11 |
1.51e-48 |
| Eating disorders |
1.15 |
0.48 |
1.82 |
0.34 |
8.10e-04 |
| OCDs |
1.79 |
1.25 |
2.34 |
0.28 |
1.41e-10 |
| PTSD |
2.28 |
1.75 |
2.82 |
0.27 |
7.21e-17 |
| Depressive disorders |
2.20 |
2.08 |
2.32 |
0.06 |
4.68e-271 |
| Bipolar disorders |
2.78 |
2.50 |
3.05 |
0.14 |
2.82e-87 |
| Female |
0.82 |
0.70 |
0.94 |
0.06 |
1.54e-43 |
| Non-binary/Self-defined |
0.42 |
-0.04 |
0.88 |
0.24 |
0.07 |
| age_category_collapsed_reordered16-18 |
0.72 |
0.41 |
1.03 |
0.16 |
4.70e-06 |
| 19-25 years |
0.93 |
0.72 |
1.15 |
0.11 |
4.29e-18 |
| 36-45 years |
-0.56 |
-0.74 |
-0.39 |
0.09 |
5.14e-10 |
| 46-55 years |
-0.95 |
-1.12 |
-0.79 |
0.08 |
9.45e-30 |
| 56-65 years |
-1.45 |
-1.62 |
-1.29 |
0.08 |
2.87e-66 |
| 66-70 years |
-2.03 |
-2.24 |
-1.82 |
0.11 |
6.47e-77 |
| 71-75 years |
-2.24 |
-2.48 |
-2.00 |
0.12 |
3.94e-72 |
| 76+ years |
-2.32 |
-2.68 |
-1.95 |
0.19 |
4.16e-35 |
| Mixed or multiple ethnic origins |
-0.33 |
-0.70 |
0.04 |
0.19 |
0.08 |
| Asian or Asian British |
-0.46 |
-0.90 |
-0.01 |
0.23 |
0.05 |
| African or African British |
-0.49 |
-1.31 |
0.33 |
0.42 |
0.24 |
| Other ethnicity |
0.18 |
-0.46 |
0.82 |
0.33 |
0.58 |
| Key worker |
-0.01 |
-0.12 |
0.09 |
0.05 |
0.83 |
| Time difference: Lockdown to baseline |
-0.21 |
-0.23 |
-0.19 |
0.01 |
3.50e-64 |
| 30973 |
0.25 |
0.25 |
1678.24 |
0.00e+00 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
3.66 |
3.41 |
3.90 |
0.12 |
6.75e-186 |
| gad.sum_score_retro |
0.66 |
0.65 |
0.67 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
2.49 |
2.36 |
2.63 |
0.07 |
9.91e-287 |
| Only depressive disorder |
1.04 |
0.88 |
1.19 |
0.08 |
7.88e-38 |
| Only anxiety disorder |
1.79 |
1.58 |
1.99 |
0.10 |
2.06e-67 |
| Eating disorders |
0.49 |
0.29 |
0.69 |
0.10 |
1.73e-06 |
| OCDs |
0.43 |
0.23 |
0.62 |
0.10 |
1.48e-05 |
| Psychotic and bipolar disorder |
0.35 |
-0.19 |
0.90 |
0.28 |
0.21 |
| Only psychotic disorder |
0.21 |
-0.26 |
0.68 |
0.24 |
0.39 |
| Only bipolar disorder |
0.32 |
0.02 |
0.62 |
0.15 |
0.03 |
| PTSD |
0.78 |
0.60 |
0.96 |
0.09 |
1.65e-17 |
| ASD |
0.64 |
0.29 |
0.99 |
0.18 |
3.79e-04 |
| ADHD |
0.11 |
-0.35 |
0.57 |
0.24 |
0.64 |
| Personality disorder |
0.61 |
0.36 |
0.87 |
0.13 |
2.64e-06 |
| Female |
0.80 |
0.68 |
0.91 |
0.06 |
1.33e-41 |
| Non-binary/Self-defined |
0.09 |
-0.37 |
0.55 |
0.24 |
0.71 |
| age_category_collapsed_reordered16-18 |
1.04 |
0.74 |
1.34 |
0.15 |
1.31e-11 |
| 19-25 years |
0.94 |
0.73 |
1.15 |
0.11 |
3.31e-18 |
| 36-45 years |
-0.50 |
-0.68 |
-0.33 |
0.09 |
3.25e-08 |
| 46-55 years |
-0.82 |
-0.99 |
-0.65 |
0.08 |
4.11e-22 |
| 56-65 years |
-1.20 |
-1.37 |
-1.04 |
0.08 |
3.04e-45 |
| 66-70 years |
-1.73 |
-1.95 |
-1.52 |
0.11 |
2.01e-56 |
| 71-75 years |
-1.93 |
-2.18 |
-1.69 |
0.12 |
2.64e-54 |
| 76+ years |
-1.99 |
-2.35 |
-1.63 |
0.18 |
3.21e-27 |
| Mixed or multiple ethnic origins |
-0.24 |
-0.61 |
0.12 |
0.19 |
0.19 |
| Asian or Asian British |
-0.13 |
-0.57 |
0.30 |
0.22 |
0.55 |
| African or African British |
-0.61 |
-1.42 |
0.19 |
0.41 |
0.13 |
| Other ethnicity |
0.39 |
-0.26 |
1.04 |
0.33 |
0.24 |
| Key worker |
0.05 |
-0.05 |
0.16 |
0.05 |
0.32 |
| Time difference: Lockdown to baseline |
-0.22 |
-0.24 |
-0.19 |
0.01 |
7.46e-68 |
| 30973 |
0.25 |
0.25 |
1678.24 |
0.00e+00 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
1.25 |
0.99 |
1.50 |
0.13 |
9.13e-22 |
| gad.sum_score_retro |
0.69 |
0.68 |
0.70 |
0.01 |
0.00e+00 |
| Anxiety disorders |
1.51 |
1.25 |
1.76 |
0.13 |
6.87e-31 |
| Eating disorders |
1.32 |
0.55 |
2.08 |
0.39 |
7.56e-04 |
| OCDs |
1.97 |
1.30 |
2.64 |
0.34 |
9.72e-09 |
| PTSD |
2.37 |
1.66 |
3.08 |
0.36 |
5.47e-11 |
| Depressive disorders |
2.45 |
2.31 |
2.58 |
0.07 |
5.43e-264 |
| Bipolar disorders |
3.06 |
2.77 |
3.35 |
0.15 |
1.54e-92 |
| Female |
0.60 |
0.48 |
0.72 |
0.06 |
8.58e-22 |
| Non-binary/Self-defined |
0.21 |
-0.28 |
0.70 |
0.25 |
0.41 |
| Age |
-134.10 |
-143.52 |
-124.67 |
4.81 |
4.59e-168 |
| Age^2 |
12.68 |
4.33 |
21.03 |
4.26 |
0.003 |
| Mixed or multiple ethnic origins |
-0.42 |
-0.82 |
-0.02 |
0.20 |
0.04 |
| Asian or Asian British |
-0.17 |
-0.70 |
0.35 |
0.27 |
0.52 |
| African or African British |
-0.33 |
-1.19 |
0.54 |
0.44 |
0.46 |
| Other ethnicity |
0.38 |
-0.36 |
1.12 |
0.38 |
0.32 |
| Key worker |
-0.03 |
-0.14 |
0.09 |
0.06 |
0.64 |
| Time difference: Lockdown to baseline |
-0.03 |
-0.06 |
0.01 |
0.02 |
0.11 |
| 23658 |
0.30 |
0.30 |
1725.06 |
0.00e+00 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
1.25 |
1.00 |
1.50 |
0.13 |
2.19e-22 |
| gad.sum_score_retro |
0.65 |
0.63 |
0.66 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
2.79 |
2.65 |
2.94 |
0.08 |
3.50e-290 |
| Only depressive disorder |
1.19 |
1.01 |
1.36 |
0.09 |
7.37e-40 |
| Only anxiety disorder |
1.76 |
1.52 |
1.99 |
0.12 |
1.02e-48 |
| Eating disorders |
0.56 |
0.35 |
0.78 |
0.11 |
3.55e-07 |
| OCDs |
0.33 |
0.13 |
0.54 |
0.11 |
0.002 |
| Psychotic and bipolar disorder |
0.45 |
-0.17 |
1.07 |
0.32 |
0.16 |
| Only psychotic disorder |
0.26 |
-0.24 |
0.77 |
0.26 |
0.31 |
| Only bipolar disorder |
0.32 |
0.01 |
0.63 |
0.16 |
0.04 |
| PTSD |
0.91 |
0.71 |
1.10 |
0.10 |
4.79e-20 |
| ASD |
0.52 |
0.11 |
0.92 |
0.20 |
0.01 |
| ADHD |
0.18 |
-0.36 |
0.71 |
0.27 |
0.52 |
| Personality disorder |
0.67 |
0.40 |
0.94 |
0.14 |
1.45e-06 |
| Female |
0.54 |
0.42 |
0.66 |
0.06 |
1.88e-18 |
| Non-binary/Self-defined |
-0.18 |
-0.67 |
0.31 |
0.25 |
0.48 |
| Age |
-116.86 |
-126.36 |
-107.36 |
4.85 |
1.09e-126 |
| Age^2 |
14.87 |
6.62 |
23.12 |
4.21 |
4.13e-04 |
| Mixed or multiple ethnic origins |
-0.34 |
-0.74 |
0.05 |
0.20 |
0.09 |
| Asian or Asian British |
0.04 |
-0.47 |
0.55 |
0.26 |
0.88 |
| African or African British |
-0.43 |
-1.27 |
0.42 |
0.43 |
0.32 |
| Other ethnicity |
0.45 |
-0.30 |
1.20 |
0.38 |
0.24 |
| Key worker |
0.06 |
-0.05 |
0.18 |
0.06 |
0.27 |
| Time difference: Lockdown to baseline |
-0.02 |
-0.05 |
0.01 |
0.02 |
0.17 |
| 23658 |
0.30 |
0.30 |
1725.06 |
0.00e+00 |
6 |
GAD retro: sensitivity
Regression: Change scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
2.16 |
1.01 |
3.31 |
0.59 |
2.36e-04 |
| Anxiety disorders |
1.11 |
-0.15 |
2.37 |
0.64 |
0.08 |
| Eating disorders |
1.88 |
-0.47 |
4.22 |
1.19 |
0.12 |
| OCDs |
1.28 |
-0.42 |
2.97 |
0.86 |
0.14 |
| PTSD |
2.04 |
0.19 |
3.90 |
0.95 |
0.03 |
| Depressive disorders |
1.15 |
-0.01 |
2.31 |
0.59 |
0.05 |
| Bipolar disorders |
1.01 |
-0.22 |
2.24 |
0.63 |
0.11 |
| 8623 |
0.00 |
0.00 |
1.03 |
0.40 |
6 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
2.55 |
1.72 |
3.38 |
0.42 |
1.97e-09 |
| Depressive and anxiety disorder |
0.73 |
-0.11 |
1.57 |
0.43 |
0.09 |
| Only depressive disorder |
0.15 |
-0.76 |
1.07 |
0.47 |
0.74 |
| Only anxiety disorder |
0.84 |
-0.11 |
1.78 |
0.48 |
0.08 |
| Eating disorders |
0.55 |
0.16 |
0.93 |
0.20 |
0.006 |
| OCDs |
-0.21 |
-0.57 |
0.15 |
0.18 |
0.25 |
| Psychotic and bipolar disorder |
-0.30 |
-1.39 |
0.79 |
0.56 |
0.59 |
| Only psychotic disorder |
-0.16 |
-1.07 |
0.74 |
0.46 |
0.73 |
| Only bipolar disorder |
-0.29 |
-0.83 |
0.24 |
0.27 |
0.28 |
| PTSD |
0.39 |
0.06 |
0.73 |
0.17 |
0.02 |
| ASD |
0.22 |
-0.49 |
0.92 |
0.36 |
0.55 |
| ADHD |
0.12 |
-0.86 |
1.09 |
0.50 |
0.81 |
| Personality disorder |
0.42 |
-0.06 |
0.90 |
0.24 |
0.09 |
| 8623 |
0.00 |
0.00 |
1.03 |
0.40 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.49 |
1.17 |
3.81 |
0.67 |
2.08e-04 |
| Anxiety disorders |
1.00 |
-0.25 |
2.24 |
0.64 |
0.12 |
| Eating disorders |
1.59 |
-0.73 |
3.92 |
1.19 |
0.18 |
| OCDs |
0.99 |
-0.68 |
2.67 |
0.86 |
0.25 |
| PTSD |
2.15 |
0.31 |
3.99 |
0.94 |
0.02 |
| Depressive disorders |
1.20 |
0.05 |
2.35 |
0.59 |
0.04 |
| Bipolar disorders |
1.17 |
-0.06 |
2.39 |
0.63 |
0.06 |
| Female |
0.62 |
0.30 |
0.94 |
0.16 |
1.54e-04 |
| Non-binary/Self-defined |
-0.54 |
-1.42 |
0.34 |
0.45 |
0.23 |
| age_category_collapsed_reordered16-18 |
-0.25 |
-1.00 |
0.50 |
0.38 |
0.52 |
| 19-25 years |
0.75 |
0.36 |
1.15 |
0.20 |
1.85e-04 |
| 36-45 years |
-0.45 |
-0.80 |
-0.10 |
0.18 |
0.01 |
| 46-55 years |
-0.66 |
-1.00 |
-0.31 |
0.18 |
1.86e-04 |
| 56-65 years |
-1.21 |
-1.60 |
-0.81 |
0.20 |
1.85e-09 |
| 66-70 years |
-1.48 |
-2.22 |
-0.74 |
0.38 |
8.68e-05 |
| 71-75 years |
-2.21 |
-3.18 |
-1.23 |
0.50 |
9.89e-06 |
| 76+ years |
-2.77 |
-4.81 |
-0.73 |
1.04 |
0.008 |
| Mixed or multiple ethnic origins |
-0.83 |
-1.63 |
-0.03 |
0.41 |
0.04 |
| Asian or Asian British |
0.14 |
-1.17 |
1.46 |
0.67 |
0.83 |
| African or African British |
-1.43 |
-3.46 |
0.60 |
1.03 |
0.17 |
| Other ethnicity |
-0.05 |
-1.27 |
1.18 |
0.63 |
0.94 |
| Time difference: Lockdown to baseline |
-0.06 |
-0.14 |
0.01 |
0.04 |
0.08 |
| 8623 |
0.00 |
0.00 |
1.03 |
0.40 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.81 |
1.73 |
3.89 |
0.55 |
3.43e-07 |
| Depressive and anxiety disorder |
0.70 |
-0.14 |
1.55 |
0.43 |
0.10 |
| Only depressive disorder |
0.37 |
-0.55 |
1.28 |
0.47 |
0.43 |
| Only anxiety disorder |
0.67 |
-0.28 |
1.61 |
0.48 |
0.17 |
| Eating disorders |
0.37 |
-0.02 |
0.76 |
0.20 |
0.06 |
| OCDs |
-0.27 |
-0.63 |
0.09 |
0.18 |
0.15 |
| Psychotic and bipolar disorder |
0.05 |
-1.04 |
1.13 |
0.55 |
0.93 |
| Only psychotic disorder |
0.11 |
-0.80 |
1.02 |
0.46 |
0.81 |
| Only bipolar disorder |
-0.16 |
-0.70 |
0.37 |
0.27 |
0.55 |
| PTSD |
0.46 |
0.12 |
0.80 |
0.17 |
0.008 |
| ASD |
0.25 |
-0.46 |
0.96 |
0.36 |
0.49 |
| ADHD |
0.21 |
-0.76 |
1.18 |
0.50 |
0.67 |
| Personality disorder |
0.29 |
-0.19 |
0.77 |
0.24 |
0.24 |
| Female |
0.59 |
0.25 |
0.93 |
0.17 |
6.96e-04 |
| Non-binary/Self-defined |
-0.76 |
-1.68 |
0.15 |
0.47 |
0.10 |
| age_category_collapsed_reordered16-18 |
-0.09 |
-0.86 |
0.67 |
0.39 |
0.81 |
| 19-25 years |
0.74 |
0.33 |
1.15 |
0.21 |
3.67e-04 |
| 36-45 years |
-0.44 |
-0.81 |
-0.08 |
0.19 |
0.02 |
| 46-55 years |
-0.65 |
-1.01 |
-0.29 |
0.18 |
4.19e-04 |
| 56-65 years |
-1.05 |
-1.47 |
-0.64 |
0.21 |
6.61e-07 |
| 66-70 years |
-1.23 |
-2.01 |
-0.45 |
0.40 |
0.002 |
| 71-75 years |
-1.70 |
-2.74 |
-0.66 |
0.53 |
0.001 |
| 76+ years |
-2.61 |
-4.83 |
-0.39 |
1.13 |
0.02 |
| Mixed or multiple ethnic origins |
-0.74 |
-1.57 |
0.09 |
0.42 |
0.08 |
| Asian or Asian British |
0.14 |
-1.20 |
1.49 |
0.69 |
0.83 |
| African or African British |
-1.78 |
-3.86 |
0.30 |
1.06 |
0.09 |
| Other ethnicity |
0.01 |
-1.24 |
1.26 |
0.64 |
0.99 |
| Key worker |
0.36 |
0.11 |
0.61 |
0.13 |
0.005 |
| Time difference: Lockdown to baseline |
-0.07 |
-0.15 |
0.00 |
0.04 |
0.06 |
| 8623 |
0.00 |
0.00 |
1.03 |
0.40 |
6 |
Regression: Absolute scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
3.61 |
2.73 |
4.50 |
0.45 |
1.14e-15 |
| gad.sum_score_retro |
0.61 |
0.60 |
0.63 |
0.01 |
0.00e+00 |
| Anxiety disorders |
1.36 |
0.39 |
2.33 |
0.50 |
0.006 |
| Eating disorders |
2.45 |
0.57 |
4.33 |
0.96 |
0.01 |
| OCDs |
1.99 |
0.69 |
3.29 |
0.66 |
0.003 |
| PTSD |
2.44 |
0.96 |
3.92 |
0.75 |
0.001 |
| Depressive disorders |
1.61 |
0.73 |
2.50 |
0.45 |
3.45e-04 |
| Bipolar disorders |
1.94 |
0.99 |
2.89 |
0.48 |
6.17e-05 |
| 10363 |
0.29 |
0.29 |
611.78 |
0.00e+00 |
7 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
4.35 |
3.72 |
4.99 |
0.32 |
3.91e-41 |
| gad.sum_score_retro |
0.57 |
0.55 |
0.59 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
1.07 |
0.44 |
1.70 |
0.32 |
8.85e-04 |
| Only depressive disorder |
-0.43 |
-1.12 |
0.26 |
0.35 |
0.22 |
| Only anxiety disorder |
0.93 |
0.21 |
1.65 |
0.37 |
0.01 |
| Eating disorders |
0.81 |
0.51 |
1.11 |
0.15 |
1.71e-07 |
| OCDs |
0.47 |
0.18 |
0.75 |
0.15 |
0.001 |
| Psychotic and bipolar disorder |
-0.24 |
-1.09 |
0.61 |
0.43 |
0.57 |
| Only psychotic disorder |
0.06 |
-0.65 |
0.76 |
0.36 |
0.87 |
| Only bipolar disorder |
0.03 |
-0.39 |
0.45 |
0.21 |
0.89 |
| PTSD |
0.71 |
0.45 |
0.98 |
0.14 |
1.61e-07 |
| ASD |
0.73 |
0.17 |
1.28 |
0.28 |
0.01 |
| ADHD |
0.27 |
-0.49 |
1.03 |
0.39 |
0.49 |
| Personality disorder |
0.95 |
0.58 |
1.32 |
0.19 |
5.63e-07 |
| 10376 |
0.01 |
0.01 |
10.21 |
2.72e-11 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
3.78 |
2.76 |
4.80 |
0.52 |
4.64e-13 |
| gad.sum_score_retro |
0.60 |
0.58 |
0.62 |
0.01 |
0.00e+00 |
| Anxiety disorders |
1.31 |
0.34 |
2.28 |
0.49 |
0.008 |
| Eating disorders |
2.31 |
0.45 |
4.18 |
0.95 |
0.01 |
| OCDs |
1.77 |
0.48 |
3.06 |
0.66 |
0.007 |
| PTSD |
2.72 |
1.25 |
4.19 |
0.75 |
2.85e-04 |
| Depressive disorders |
1.77 |
0.88 |
2.65 |
0.45 |
8.75e-05 |
| Bipolar disorders |
2.23 |
1.29 |
3.18 |
0.48 |
3.85e-06 |
| Female |
0.56 |
0.31 |
0.81 |
0.13 |
1.05e-05 |
| Non-binary/Self-defined |
0.28 |
-0.41 |
0.98 |
0.35 |
0.43 |
| age_category_collapsed_reordered16-18 |
0.68 |
0.10 |
1.27 |
0.30 |
0.02 |
| 19-25 years |
0.86 |
0.54 |
1.17 |
0.16 |
9.16e-08 |
| 36-45 years |
-0.40 |
-0.68 |
-0.12 |
0.14 |
0.005 |
| 46-55 years |
-0.62 |
-0.90 |
-0.35 |
0.14 |
7.70e-06 |
| 56-65 years |
-1.29 |
-1.60 |
-0.97 |
0.16 |
1.16e-15 |
| 66-70 years |
-1.98 |
-2.56 |
-1.39 |
0.30 |
3.43e-11 |
| 71-75 years |
-2.56 |
-3.34 |
-1.79 |
0.40 |
1.10e-10 |
| 76+ years |
-2.51 |
-4.12 |
-0.90 |
0.82 |
0.002 |
| Mixed or multiple ethnic origins |
-0.53 |
-1.15 |
0.10 |
0.32 |
0.10 |
| Asian or Asian British |
0.06 |
-0.97 |
1.09 |
0.53 |
0.91 |
| African or African British |
-0.32 |
-1.99 |
1.35 |
0.85 |
0.71 |
| Other ethnicity |
0.08 |
-0.88 |
1.03 |
0.49 |
0.87 |
| Key worker |
-0.14 |
-0.33 |
0.06 |
0.10 |
0.16 |
| Time difference: Lockdown to baseline |
-0.03 |
-0.09 |
0.02 |
0.03 |
0.26 |
| 10376 |
0.01 |
0.01 |
10.21 |
2.72e-11 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
4.57 |
3.74 |
5.40 |
0.42 |
3.31e-27 |
| gad.sum_score_retro |
0.56 |
0.54 |
0.58 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
1.12 |
0.49 |
1.76 |
0.32 |
5.20e-04 |
| Only depressive disorder |
-0.14 |
-0.82 |
0.55 |
0.35 |
0.70 |
| Only anxiety disorder |
0.80 |
0.08 |
1.52 |
0.37 |
0.03 |
| Eating disorders |
0.65 |
0.35 |
0.95 |
0.15 |
2.74e-05 |
| OCDs |
0.39 |
0.11 |
0.67 |
0.14 |
0.007 |
| Psychotic and bipolar disorder |
0.02 |
-0.83 |
0.86 |
0.43 |
0.97 |
| Only psychotic disorder |
0.23 |
-0.47 |
0.93 |
0.36 |
0.52 |
| Only bipolar disorder |
0.18 |
-0.23 |
0.60 |
0.21 |
0.39 |
| PTSD |
0.80 |
0.53 |
1.07 |
0.14 |
4.01e-09 |
| ASD |
0.60 |
0.05 |
1.16 |
0.28 |
0.03 |
| ADHD |
0.24 |
-0.51 |
0.99 |
0.38 |
0.53 |
| Personality disorder |
0.82 |
0.45 |
1.19 |
0.19 |
1.53e-05 |
| Female |
0.43 |
0.16 |
0.69 |
0.13 |
0.001 |
| Non-binary/Self-defined |
-0.19 |
-0.90 |
0.52 |
0.36 |
0.60 |
| age_category_collapsed_reordered16-18 |
0.78 |
0.20 |
1.37 |
0.30 |
0.009 |
| 19-25 years |
0.84 |
0.52 |
1.16 |
0.16 |
2.98e-07 |
| 36-45 years |
-0.36 |
-0.64 |
-0.07 |
0.15 |
0.01 |
| 46-55 years |
-0.54 |
-0.82 |
-0.25 |
0.14 |
2.10e-04 |
| 56-65 years |
-1.06 |
-1.39 |
-0.74 |
0.17 |
1.74e-10 |
| 66-70 years |
-1.75 |
-2.35 |
-1.14 |
0.31 |
1.38e-08 |
| 71-75 years |
-2.00 |
-2.82 |
-1.18 |
0.42 |
1.95e-06 |
| 76+ years |
-2.09 |
-3.79 |
-0.38 |
0.87 |
0.02 |
| Mixed or multiple ethnic origins |
-0.49 |
-1.13 |
0.15 |
0.33 |
0.13 |
| Asian or Asian British |
0.19 |
-0.86 |
1.24 |
0.53 |
0.73 |
| African or African British |
-0.52 |
-2.25 |
1.20 |
0.88 |
0.55 |
| Other ethnicity |
0.20 |
-0.78 |
1.18 |
0.50 |
0.69 |
| Key worker |
-0.01 |
-0.21 |
0.19 |
0.10 |
0.93 |
| Time difference: Lockdown to baseline |
-0.04 |
-0.10 |
0.02 |
0.03 |
0.22 |
| 10376 |
0.01 |
0.01 |
10.21 |
2.72e-11 |
6 |
PHQ baseline, not controlling for prior symptoms
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
3.31 |
3.20 |
3.42 |
0.05 |
0.00e+00 |
| Anxiety disorders |
3.59 |
3.31 |
3.88 |
0.15 |
1.16e-131 |
| Eating disorders |
3.92 |
3.00 |
4.84 |
0.47 |
6.66e-17 |
| OCDs |
5.90 |
5.15 |
6.64 |
0.38 |
5.02e-54 |
| PTSD |
5.21 |
4.48 |
5.94 |
0.37 |
1.54e-44 |
| Depressive disorders |
7.16 |
7.02 |
7.30 |
0.07 |
0.00e+00 |
| Bipolar disorders |
9.59 |
9.24 |
9.95 |
0.18 |
0.00e+00 |
| 32662 |
0.25 |
0.25 |
1854.75 |
0.00e+00 |
6 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
3.56 |
3.46 |
3.66 |
0.05 |
0.00e+00 |
| Depressive and anxiety disorder |
6.64 |
6.49 |
6.79 |
0.08 |
0.00e+00 |
| Only depressive disorder |
3.53 |
3.33 |
3.73 |
0.10 |
7.11e-257 |
| Only anxiety disorder |
3.22 |
2.97 |
3.48 |
0.13 |
5.24e-133 |
| Eating disorders |
2.18 |
1.92 |
2.45 |
0.14 |
4.24e-57 |
| OCDs |
2.04 |
1.78 |
2.30 |
0.13 |
4.62e-54 |
| Psychotic and bipolar disorder |
0.27 |
-0.46 |
1.00 |
0.37 |
0.47 |
| Only psychotic disorder |
0.80 |
0.17 |
1.42 |
0.32 |
0.01 |
| Only bipolar disorder |
1.31 |
0.91 |
1.70 |
0.20 |
6.16e-11 |
| PTSD |
2.05 |
1.81 |
2.29 |
0.12 |
1.16e-63 |
| ASD |
2.80 |
2.34 |
3.27 |
0.24 |
4.82e-32 |
| ADHD |
1.90 |
1.28 |
2.51 |
0.31 |
1.73e-09 |
| Personality disorder |
3.40 |
3.06 |
3.74 |
0.17 |
6.36e-84 |
| 32662 |
0.25 |
0.25 |
1854.75 |
0.00e+00 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
6.23 |
5.90 |
6.55 |
0.17 |
9.38e-304 |
| Anxiety disorders |
2.16 |
1.87 |
2.45 |
0.15 |
1.17e-47 |
| Eating disorders |
2.10 |
1.20 |
3.01 |
0.46 |
5.29e-06 |
| OCDs |
2.98 |
2.25 |
3.71 |
0.37 |
1.74e-15 |
| PTSD |
4.09 |
3.36 |
4.81 |
0.37 |
3.05e-28 |
| Depressive disorders |
5.87 |
5.72 |
6.03 |
0.08 |
0.00e+00 |
| Bipolar disorders |
8.20 |
7.85 |
8.55 |
0.18 |
0.00e+00 |
| Female |
0.93 |
0.78 |
1.09 |
0.08 |
6.72e-32 |
| Non-binary/Self-defined |
2.50 |
1.88 |
3.12 |
0.32 |
3.22e-15 |
| age_category_collapsed_reordered16-18 |
5.89 |
5.48 |
6.31 |
0.21 |
4.13e-167 |
| 19-25 years |
2.29 |
2.00 |
2.57 |
0.15 |
5.42e-55 |
| 36-45 years |
-0.81 |
-1.05 |
-0.57 |
0.12 |
3.85e-11 |
| 46-55 years |
-1.27 |
-1.49 |
-1.05 |
0.11 |
1.39e-29 |
| 56-65 years |
-2.42 |
-2.64 |
-2.20 |
0.11 |
5.41e-103 |
| 66-70 years |
-3.62 |
-3.90 |
-3.34 |
0.14 |
1.04e-140 |
| 71-75 years |
-3.76 |
-4.08 |
-3.44 |
0.16 |
5.56e-115 |
| 76+ years |
-3.71 |
-4.20 |
-3.22 |
0.25 |
1.01e-49 |
| Mixed or multiple ethnic origins |
0.37 |
-0.13 |
0.86 |
0.25 |
0.15 |
| Asian or Asian British |
-0.16 |
-0.77 |
0.45 |
0.31 |
0.60 |
| African or African British |
-0.30 |
-1.41 |
0.81 |
0.57 |
0.60 |
| Other ethnicity |
1.14 |
0.29 |
2.00 |
0.44 |
0.009 |
| Time difference: Lockdown to baseline |
-0.21 |
-0.24 |
-0.18 |
0.02 |
1.52e-36 |
| 32662 |
0.25 |
0.25 |
1854.75 |
0.00e+00 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
6.36 |
6.04 |
6.68 |
0.16 |
3.95e-323 |
| Depressive and anxiety disorder |
5.55 |
5.38 |
5.71 |
0.08 |
0.00e+00 |
| Only depressive disorder |
3.37 |
3.16 |
3.57 |
0.11 |
1.32e-219 |
| Only anxiety disorder |
2.04 |
1.77 |
2.30 |
0.13 |
4.96e-52 |
| Eating disorders |
1.56 |
1.29 |
1.82 |
0.13 |
4.38e-31 |
| OCDs |
1.44 |
1.19 |
1.69 |
0.13 |
6.82e-29 |
| Psychotic and bipolar disorder |
0.55 |
-0.16 |
1.26 |
0.36 |
0.13 |
| Only psychotic disorder |
0.87 |
0.26 |
1.48 |
0.31 |
0.005 |
| Only bipolar disorder |
1.48 |
1.10 |
1.86 |
0.20 |
3.91e-14 |
| PTSD |
2.07 |
1.84 |
2.31 |
0.12 |
2.84e-67 |
| ASD |
1.47 |
1.01 |
1.93 |
0.23 |
3.78e-10 |
| ADHD |
1.10 |
0.50 |
1.71 |
0.31 |
3.54e-04 |
| Personality disorder |
3.05 |
2.72 |
3.39 |
0.17 |
5.49e-71 |
| Female |
0.84 |
0.68 |
0.99 |
0.08 |
5.13e-27 |
| Non-binary/Self-defined |
1.38 |
0.76 |
1.99 |
0.31 |
1.03e-05 |
| age_category_collapsed_reordered16-18 |
5.94 |
5.54 |
6.34 |
0.20 |
4.13e-184 |
| 19-25 years |
2.16 |
1.88 |
2.44 |
0.14 |
1.63e-51 |
| 36-45 years |
-0.60 |
-0.83 |
-0.36 |
0.12 |
5.81e-07 |
| 46-55 years |
-0.84 |
-1.05 |
-0.62 |
0.11 |
5.61e-14 |
| 56-65 years |
-1.91 |
-2.13 |
-1.69 |
0.11 |
1.08e-65 |
| 66-70 years |
-3.18 |
-3.46 |
-2.89 |
0.14 |
8.09e-108 |
| 71-75 years |
-3.36 |
-3.68 |
-3.04 |
0.16 |
6.23e-93 |
| 76+ years |
-3.22 |
-3.70 |
-2.74 |
0.24 |
1.05e-39 |
| Mixed or multiple ethnic origins |
0.37 |
-0.12 |
0.86 |
0.25 |
0.14 |
| Asian or Asian British |
0.29 |
-0.29 |
0.87 |
0.30 |
0.33 |
| African or African British |
-0.26 |
-1.32 |
0.79 |
0.54 |
0.62 |
| Other ethnicity |
1.03 |
0.18 |
1.88 |
0.44 |
0.02 |
| Key worker |
-0.68 |
-0.82 |
-0.54 |
0.07 |
4.66e-21 |
| Time difference: Lockdown to baseline |
-0.22 |
-0.25 |
-0.19 |
0.02 |
1.38e-41 |
| 32662 |
0.25 |
0.25 |
1854.75 |
0.00e+00 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.25 |
1.90 |
2.59 |
0.18 |
2.77e-37 |
| Anxiety disorders |
2.02 |
1.68 |
2.37 |
0.18 |
2.63e-30 |
| Eating disorders |
2.31 |
1.27 |
3.35 |
0.53 |
1.43e-05 |
| OCDs |
3.91 |
3.01 |
4.82 |
0.46 |
2.59e-17 |
| PTSD |
3.93 |
2.95 |
4.91 |
0.50 |
3.25e-15 |
| Depressive disorders |
6.07 |
5.90 |
6.25 |
0.09 |
0.00e+00 |
| Bipolar disorders |
8.33 |
7.95 |
8.71 |
0.19 |
0.00e+00 |
| Female |
0.57 |
0.40 |
0.74 |
0.09 |
2.32e-11 |
| Non-binary/Self-defined |
2.11 |
1.44 |
2.78 |
0.34 |
6.82e-10 |
| Age |
-285.84 |
-298.50 |
-273.17 |
6.46 |
0.00e+00 |
| Age^2 |
31.24 |
19.79 |
42.69 |
5.84 |
9.08e-08 |
| Mixed or multiple ethnic origins |
0.43 |
-0.11 |
0.98 |
0.28 |
0.12 |
| Asian or Asian British |
0.02 |
-0.72 |
0.75 |
0.38 |
0.96 |
| African or African British |
-0.18 |
-1.38 |
1.02 |
0.61 |
0.77 |
| Other ethnicity |
1.41 |
0.42 |
2.40 |
0.50 |
0.005 |
| Time difference: Lockdown to baseline |
0.10 |
0.06 |
0.15 |
0.02 |
1.93e-06 |
| 25344 |
0.31 |
0.31 |
1865.02 |
0.00e+00 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.66 |
2.32 |
3.00 |
0.17 |
1.80e-53 |
| Depressive and anxiety disorder |
5.83 |
5.65 |
6.02 |
0.09 |
0.00e+00 |
| Only depressive disorder |
3.60 |
3.37 |
3.84 |
0.12 |
8.27e-196 |
| Only anxiety disorder |
2.13 |
1.83 |
2.44 |
0.16 |
1.22e-41 |
| Eating disorders |
1.79 |
1.51 |
2.08 |
0.15 |
1.62e-34 |
| OCDs |
1.46 |
1.18 |
1.74 |
0.14 |
3.28e-25 |
| Psychotic and bipolar disorder |
0.34 |
-0.47 |
1.15 |
0.41 |
0.41 |
| Only psychotic disorder |
0.83 |
0.17 |
1.49 |
0.34 |
0.01 |
| Only bipolar disorder |
1.48 |
1.08 |
1.88 |
0.20 |
5.26e-13 |
| PTSD |
2.05 |
1.80 |
2.31 |
0.13 |
2.74e-55 |
| ASD |
1.57 |
1.04 |
2.10 |
0.27 |
6.15e-09 |
| ADHD |
0.77 |
0.06 |
1.47 |
0.36 |
0.03 |
| Personality disorder |
2.85 |
2.49 |
3.21 |
0.18 |
1.53e-53 |
| Female |
0.43 |
0.27 |
0.59 |
0.08 |
2.44e-07 |
| Non-binary/Self-defined |
1.09 |
0.43 |
1.74 |
0.34 |
0.001 |
| Age |
-255.64 |
-268.55 |
-242.74 |
6.58 |
4.56e-319 |
| Age^2 |
14.59 |
3.10 |
26.08 |
5.86 |
0.01 |
| Mixed or multiple ethnic origins |
0.34 |
-0.20 |
0.88 |
0.27 |
0.22 |
| Asian or Asian British |
0.38 |
-0.32 |
1.09 |
0.36 |
0.28 |
| African or African British |
-0.23 |
-1.38 |
0.91 |
0.58 |
0.69 |
| Other ethnicity |
1.18 |
0.19 |
2.17 |
0.50 |
0.02 |
| Key worker |
-0.71 |
-0.87 |
-0.56 |
0.08 |
4.35e-20 |
| Time difference: Lockdown to baseline |
0.10 |
0.05 |
0.14 |
0.02 |
4.77e-06 |
| 25344 |
0.31 |
0.31 |
1865.02 |
0.00e+00 |
6 |
PHQ prepan
Regression: Change scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
-1.65 |
-2.63 |
-0.66 |
0.50 |
0.001 |
| Anxiety disorders |
1.89 |
0.81 |
2.98 |
0.55 |
6.12e-04 |
| Eating disorders |
0.01 |
-2.06 |
2.07 |
1.05 |
1.00 |
| OCDs |
1.87 |
0.42 |
3.32 |
0.74 |
0.01 |
| PTSD |
1.16 |
-0.51 |
2.83 |
0.85 |
0.17 |
| Depressive disorders |
1.24 |
0.25 |
2.22 |
0.50 |
0.01 |
| Bipolar disorders |
0.78 |
-0.27 |
1.84 |
0.54 |
0.15 |
| 11993 |
0.00 |
0.00 |
3.70 |
0.001 |
6 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
-1.55 |
-2.26 |
-0.84 |
0.36 |
1.69e-05 |
| Depressive and anxiety disorder |
1.08 |
0.36 |
1.79 |
0.37 |
0.003 |
| Only depressive disorder |
0.94 |
0.16 |
1.71 |
0.39 |
0.02 |
| Only anxiety disorder |
1.75 |
0.94 |
2.56 |
0.41 |
2.28e-05 |
| Eating disorders |
0.37 |
0.02 |
0.72 |
0.18 |
0.04 |
| OCDs |
0.01 |
-0.32 |
0.33 |
0.17 |
0.96 |
| Psychotic and bipolar disorder |
-0.79 |
-1.75 |
0.17 |
0.49 |
0.11 |
| Only psychotic disorder |
0.13 |
-0.66 |
0.92 |
0.40 |
0.75 |
| Only bipolar disorder |
-0.32 |
-0.80 |
0.15 |
0.24 |
0.18 |
| PTSD |
-0.17 |
-0.48 |
0.13 |
0.16 |
0.26 |
| ASD |
0.35 |
-0.28 |
0.98 |
0.32 |
0.28 |
| ADHD |
0.07 |
-0.79 |
0.93 |
0.44 |
0.87 |
| Personality disorder |
-0.02 |
-0.44 |
0.41 |
0.22 |
0.93 |
| 11993 |
0.00 |
0.00 |
3.70 |
0.001 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-2.17 |
-3.31 |
-1.04 |
0.58 |
1.76e-04 |
| Anxiety disorders |
1.83 |
0.75 |
2.92 |
0.55 |
9.14e-04 |
| Eating disorders |
-0.13 |
-2.19 |
1.93 |
1.05 |
0.90 |
| OCDs |
1.72 |
0.27 |
3.17 |
0.74 |
0.02 |
| PTSD |
0.95 |
-0.73 |
2.63 |
0.86 |
0.27 |
| Depressive disorders |
1.20 |
0.21 |
2.19 |
0.51 |
0.02 |
| Bipolar disorders |
0.83 |
-0.23 |
1.89 |
0.54 |
0.12 |
| Female |
0.31 |
0.03 |
0.58 |
0.14 |
0.03 |
| Non-binary/Self-defined |
0.07 |
-0.73 |
0.88 |
0.41 |
0.86 |
| age_category_collapsed_reordered16-18 |
0.07 |
-0.62 |
0.75 |
0.35 |
0.85 |
| 19-25 years |
0.07 |
-0.30 |
0.44 |
0.19 |
0.70 |
| 36-45 years |
0.01 |
-0.31 |
0.33 |
0.16 |
0.95 |
| 46-55 years |
-0.30 |
-0.61 |
0.01 |
0.16 |
0.06 |
| 56-65 years |
-0.32 |
-0.66 |
0.03 |
0.18 |
0.07 |
| 66-70 years |
-0.23 |
-0.84 |
0.37 |
0.31 |
0.45 |
| 71-75 years |
-0.39 |
-1.19 |
0.41 |
0.41 |
0.34 |
| 76+ years |
-0.16 |
-1.67 |
1.34 |
0.77 |
0.83 |
| Mixed or multiple ethnic origins |
-0.03 |
-0.75 |
0.69 |
0.37 |
0.94 |
| Asian or Asian British |
-1.14 |
-2.32 |
0.04 |
0.60 |
0.06 |
| African or African British |
-0.77 |
-2.66 |
1.12 |
0.96 |
0.42 |
| Other ethnicity |
-0.28 |
-1.36 |
0.80 |
0.55 |
0.61 |
| Time difference: Lockdown to baseline |
0.06 |
0.00 |
0.13 |
0.03 |
0.06 |
| 11993 |
0.00 |
0.00 |
3.70 |
0.001 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-2.14 |
-3.08 |
-1.21 |
0.48 |
6.68e-06 |
| Depressive and anxiety disorder |
1.09 |
0.37 |
1.81 |
0.37 |
0.003 |
| Only depressive disorder |
0.99 |
0.21 |
1.77 |
0.40 |
0.01 |
| Only anxiety disorder |
1.72 |
0.91 |
2.54 |
0.42 |
3.52e-05 |
| Eating disorders |
0.32 |
-0.03 |
0.68 |
0.18 |
0.07 |
| OCDs |
-0.02 |
-0.34 |
0.31 |
0.17 |
0.92 |
| Psychotic and bipolar disorder |
-0.69 |
-1.65 |
0.28 |
0.49 |
0.16 |
| Only psychotic disorder |
0.15 |
-0.65 |
0.94 |
0.41 |
0.72 |
| Only bipolar disorder |
-0.22 |
-0.70 |
0.25 |
0.24 |
0.36 |
| PTSD |
-0.17 |
-0.48 |
0.14 |
0.16 |
0.27 |
| ASD |
0.35 |
-0.29 |
0.99 |
0.33 |
0.29 |
| ADHD |
0.05 |
-0.81 |
0.91 |
0.44 |
0.91 |
| Personality disorder |
-0.06 |
-0.48 |
0.37 |
0.22 |
0.80 |
| Female |
0.26 |
-0.04 |
0.55 |
0.15 |
0.09 |
| Non-binary/Self-defined |
-0.11 |
-0.94 |
0.72 |
0.42 |
0.79 |
| age_category_collapsed_reordered16-18 |
0.05 |
-0.64 |
0.74 |
0.35 |
0.90 |
| 19-25 years |
0.04 |
-0.34 |
0.42 |
0.19 |
0.83 |
| 36-45 years |
-0.02 |
-0.35 |
0.31 |
0.17 |
0.92 |
| 46-55 years |
-0.32 |
-0.64 |
0.00 |
0.16 |
0.05 |
| 56-65 years |
-0.33 |
-0.69 |
0.04 |
0.19 |
0.08 |
| 66-70 years |
-0.20 |
-0.84 |
0.43 |
0.32 |
0.53 |
| 71-75 years |
-0.53 |
-1.38 |
0.32 |
0.43 |
0.22 |
| 76+ years |
0.29 |
-1.36 |
1.94 |
0.84 |
0.73 |
| Mixed or multiple ethnic origins |
0.02 |
-0.73 |
0.77 |
0.38 |
0.96 |
| Asian or Asian British |
-1.19 |
-2.41 |
0.03 |
0.62 |
0.06 |
| African or African British |
-1.35 |
-3.29 |
0.59 |
0.99 |
0.17 |
| Other ethnicity |
-0.22 |
-1.35 |
0.92 |
0.58 |
0.71 |
| Key worker |
0.12 |
-0.10 |
0.35 |
0.12 |
0.29 |
| Time difference: Lockdown to baseline |
0.06 |
0.00 |
0.13 |
0.03 |
0.06 |
| 11993 |
0.00 |
0.00 |
3.70 |
0.001 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-2.30 |
-3.41 |
-1.18 |
0.57 |
5.43e-05 |
| Anxiety disorders |
1.84 |
0.76 |
2.92 |
0.55 |
8.70e-04 |
| Eating disorders |
-0.12 |
-2.18 |
1.94 |
1.05 |
0.91 |
| OCDs |
1.72 |
0.27 |
3.17 |
0.74 |
0.02 |
| PTSD |
0.98 |
-0.70 |
2.66 |
0.86 |
0.25 |
| Depressive disorders |
1.21 |
0.22 |
2.20 |
0.50 |
0.02 |
| Bipolar disorders |
0.85 |
-0.21 |
1.91 |
0.54 |
0.12 |
| Female |
0.30 |
0.03 |
0.58 |
0.14 |
0.03 |
| Non-binary/Self-defined |
0.06 |
-0.74 |
0.87 |
0.41 |
0.88 |
| Age |
-16.03 |
-27.79 |
-4.27 |
6.00 |
0.008 |
| Age^2 |
0.42 |
-11.08 |
11.92 |
5.87 |
0.94 |
| Mixed or multiple ethnic origins |
-0.03 |
-0.75 |
0.69 |
0.37 |
0.93 |
| Asian or Asian British |
-1.13 |
-2.31 |
0.05 |
0.60 |
0.06 |
| African or African British |
-0.78 |
-2.67 |
1.11 |
0.96 |
0.42 |
| Other ethnicity |
-0.28 |
-1.36 |
0.80 |
0.55 |
0.61 |
| Time difference: Lockdown to baseline |
0.06 |
0.00 |
0.13 |
0.03 |
0.06 |
| 11993 |
0.00 |
0.00 |
3.70 |
0.001 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-2.28 |
-3.18 |
-1.38 |
0.46 |
7.14e-07 |
| Depressive and anxiety disorder |
1.10 |
0.38 |
1.82 |
0.37 |
0.003 |
| Only depressive disorder |
1.00 |
0.22 |
1.78 |
0.40 |
0.01 |
| Only anxiety disorder |
1.73 |
0.91 |
2.55 |
0.42 |
3.20e-05 |
| Eating disorders |
0.32 |
-0.03 |
0.67 |
0.18 |
0.07 |
| OCDs |
-0.02 |
-0.34 |
0.31 |
0.17 |
0.91 |
| Psychotic and bipolar disorder |
-0.69 |
-1.65 |
0.27 |
0.49 |
0.16 |
| Only psychotic disorder |
0.16 |
-0.63 |
0.96 |
0.41 |
0.69 |
| Only bipolar disorder |
-0.22 |
-0.69 |
0.26 |
0.24 |
0.37 |
| PTSD |
-0.17 |
-0.48 |
0.13 |
0.16 |
0.26 |
| ASD |
0.34 |
-0.30 |
0.98 |
0.33 |
0.30 |
| ADHD |
0.06 |
-0.80 |
0.92 |
0.44 |
0.89 |
| Personality disorder |
-0.06 |
-0.49 |
0.37 |
0.22 |
0.79 |
| Female |
0.25 |
-0.04 |
0.54 |
0.15 |
0.09 |
| Non-binary/Self-defined |
-0.12 |
-0.95 |
0.71 |
0.42 |
0.77 |
| Age |
-15.89 |
-28.30 |
-3.48 |
6.33 |
0.01 |
| Age^2 |
0.65 |
-11.72 |
13.01 |
6.31 |
0.92 |
| Mixed or multiple ethnic origins |
0.02 |
-0.74 |
0.77 |
0.38 |
0.96 |
| Asian or Asian British |
-1.19 |
-2.41 |
0.03 |
0.62 |
0.06 |
| African or African British |
-1.37 |
-3.31 |
0.57 |
0.99 |
0.17 |
| Other ethnicity |
-0.21 |
-1.35 |
0.92 |
0.58 |
0.71 |
| Key worker |
0.12 |
-0.11 |
0.34 |
0.12 |
0.31 |
| Time difference: Lockdown to baseline |
0.06 |
0.00 |
0.13 |
0.03 |
0.06 |
| 11993 |
0.00 |
0.00 |
3.70 |
0.001 |
6 |
Regression: Absolute scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
2.19 |
1.30 |
3.07 |
0.45 |
1.23e-06 |
| phq.sum_score_prepan |
0.61 |
0.60 |
0.62 |
0.01 |
0.00e+00 |
| Anxiety disorders |
0.83 |
-0.13 |
1.80 |
0.49 |
0.09 |
| Eating disorders |
0.09 |
-1.75 |
1.92 |
0.94 |
0.93 |
| OCDs |
1.90 |
0.61 |
3.19 |
0.66 |
0.004 |
| PTSD |
1.04 |
-0.44 |
2.53 |
0.76 |
0.17 |
| Depressive disorders |
1.80 |
0.92 |
2.68 |
0.45 |
6.12e-05 |
| Bipolar disorders |
2.13 |
1.18 |
3.07 |
0.48 |
9.86e-06 |
| 11993 |
0.41 |
0.41 |
1167.23 |
0.00e+00 |
7 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
2.76 |
2.12 |
3.40 |
0.33 |
3.18e-17 |
| phq.sum_score_prepan |
0.59 |
0.57 |
0.60 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
1.18 |
0.55 |
1.81 |
0.32 |
2.47e-04 |
| Only depressive disorder |
0.52 |
-0.16 |
1.20 |
0.35 |
0.13 |
| Only anxiety disorder |
0.40 |
-0.32 |
1.11 |
0.37 |
0.28 |
| Eating disorders |
1.02 |
0.72 |
1.33 |
0.16 |
6.68e-11 |
| OCDs |
0.68 |
0.39 |
0.96 |
0.15 |
4.12e-06 |
| Psychotic and bipolar disorder |
-0.69 |
-1.53 |
0.16 |
0.43 |
0.11 |
| Only psychotic disorder |
0.19 |
-0.50 |
0.89 |
0.36 |
0.58 |
| Only bipolar disorder |
0.15 |
-0.27 |
0.56 |
0.21 |
0.49 |
| PTSD |
0.58 |
0.31 |
0.85 |
0.14 |
2.86e-05 |
| ASD |
1.04 |
0.48 |
1.59 |
0.28 |
2.62e-04 |
| ADHD |
0.46 |
-0.30 |
1.22 |
0.39 |
0.23 |
| Personality disorder |
1.28 |
0.90 |
1.66 |
0.19 |
3.03e-11 |
| 12024 |
0.02 |
0.02 |
41.62 |
1.65e-50 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.03 |
1.01 |
3.06 |
0.52 |
9.75e-05 |
| phq.sum_score_prepan |
0.58 |
0.57 |
0.59 |
0.01 |
0.00e+00 |
| Anxiety disorders |
0.75 |
-0.22 |
1.71 |
0.49 |
0.13 |
| Eating disorders |
0.00 |
-1.81 |
1.82 |
0.93 |
1.00 |
| OCDs |
1.58 |
0.30 |
2.86 |
0.65 |
0.02 |
| PTSD |
1.18 |
-0.30 |
2.66 |
0.76 |
0.12 |
| Depressive disorders |
2.00 |
1.12 |
2.88 |
0.45 |
8.24e-06 |
| Bipolar disorders |
2.48 |
1.54 |
3.42 |
0.48 |
2.52e-07 |
| Female |
0.34 |
0.10 |
0.58 |
0.12 |
0.006 |
| Non-binary/Self-defined |
0.80 |
0.09 |
1.50 |
0.36 |
0.03 |
| age_category_collapsed_reordered16-18 |
1.81 |
1.19 |
2.42 |
0.31 |
7.75e-09 |
| 19-25 years |
0.81 |
0.49 |
1.14 |
0.17 |
1.03e-06 |
| 36-45 years |
-0.20 |
-0.48 |
0.08 |
0.14 |
0.16 |
| 46-55 years |
-0.47 |
-0.75 |
-0.20 |
0.14 |
6.98e-04 |
| 56-65 years |
-1.06 |
-1.37 |
-0.76 |
0.16 |
1.50e-11 |
| 66-70 years |
-2.01 |
-2.55 |
-1.46 |
0.28 |
4.35e-13 |
| 71-75 years |
-2.46 |
-3.17 |
-1.75 |
0.36 |
1.42e-11 |
| 76+ years |
-2.29 |
-3.62 |
-0.97 |
0.68 |
7.11e-04 |
| Mixed or multiple ethnic origins |
0.10 |
-0.53 |
0.74 |
0.33 |
0.75 |
| Asian or Asian British |
-0.80 |
-1.84 |
0.25 |
0.53 |
0.13 |
| African or African British |
-0.25 |
-1.92 |
1.41 |
0.85 |
0.77 |
| Other ethnicity |
0.15 |
-0.80 |
1.10 |
0.49 |
0.76 |
| Key worker |
-0.58 |
-0.77 |
-0.39 |
0.10 |
3.31e-09 |
| Time difference: Lockdown to baseline |
0.08 |
0.02 |
0.13 |
0.03 |
0.009 |
| 12024 |
0.02 |
0.02 |
41.62 |
1.65e-50 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.70 |
1.87 |
3.53 |
0.42 |
2.11e-10 |
| phq.sum_score_prepan |
0.56 |
0.55 |
0.58 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
1.35 |
0.71 |
1.98 |
0.32 |
2.96e-05 |
| Only depressive disorder |
0.90 |
0.22 |
1.58 |
0.35 |
0.010 |
| Only anxiety disorder |
0.30 |
-0.41 |
1.02 |
0.36 |
0.41 |
| Eating disorders |
0.92 |
0.62 |
1.23 |
0.16 |
3.68e-09 |
| OCDs |
0.57 |
0.28 |
0.86 |
0.15 |
9.46e-05 |
| Psychotic and bipolar disorder |
-0.50 |
-1.34 |
0.34 |
0.43 |
0.25 |
| Only psychotic disorder |
0.24 |
-0.45 |
0.94 |
0.35 |
0.50 |
| Only bipolar disorder |
0.31 |
-0.10 |
0.73 |
0.21 |
0.14 |
| PTSD |
0.66 |
0.39 |
0.93 |
0.14 |
1.94e-06 |
| ASD |
0.68 |
0.13 |
1.24 |
0.29 |
0.02 |
| ADHD |
0.32 |
-0.43 |
1.08 |
0.39 |
0.40 |
| Personality disorder |
1.19 |
0.82 |
1.57 |
0.19 |
5.96e-10 |
| Female |
0.12 |
-0.14 |
0.37 |
0.13 |
0.37 |
| Non-binary/Self-defined |
0.28 |
-0.44 |
1.01 |
0.37 |
0.44 |
| age_category_collapsed_reordered16-18 |
1.89 |
1.28 |
2.49 |
0.31 |
1.10e-09 |
| 19-25 years |
0.83 |
0.50 |
1.16 |
0.17 |
8.76e-07 |
| 36-45 years |
-0.18 |
-0.47 |
0.11 |
0.15 |
0.23 |
| 46-55 years |
-0.35 |
-0.63 |
-0.07 |
0.14 |
0.02 |
| 56-65 years |
-0.90 |
-1.22 |
-0.58 |
0.16 |
4.07e-08 |
| 66-70 years |
-1.80 |
-2.36 |
-1.25 |
0.29 |
2.63e-10 |
| 71-75 years |
-2.30 |
-3.04 |
-1.55 |
0.38 |
1.62e-09 |
| 76+ years |
-1.68 |
-3.12 |
-0.23 |
0.74 |
0.02 |
| Mixed or multiple ethnic origins |
0.07 |
-0.59 |
0.73 |
0.34 |
0.83 |
| Asian or Asian British |
-0.67 |
-1.74 |
0.39 |
0.54 |
0.21 |
| African or African British |
-0.59 |
-2.28 |
1.11 |
0.87 |
0.50 |
| Other ethnicity |
0.21 |
-0.78 |
1.20 |
0.51 |
0.68 |
| Key worker |
-0.45 |
-0.65 |
-0.25 |
0.10 |
8.96e-06 |
| Time difference: Lockdown to baseline |
0.07 |
0.01 |
0.13 |
0.03 |
0.02 |
| 12024 |
0.02 |
0.02 |
41.62 |
1.65e-50 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
1.77 |
0.77 |
2.78 |
0.51 |
5.39e-04 |
| phq.sum_score_prepan |
0.58 |
0.57 |
0.60 |
0.01 |
0.00e+00 |
| Anxiety disorders |
0.73 |
-0.23 |
1.69 |
0.49 |
0.14 |
| Eating disorders |
-0.01 |
-1.83 |
1.81 |
0.93 |
0.99 |
| OCDs |
1.61 |
0.33 |
2.90 |
0.65 |
0.01 |
| PTSD |
1.11 |
-0.37 |
2.60 |
0.76 |
0.14 |
| Depressive disorders |
1.94 |
1.07 |
2.82 |
0.45 |
1.45e-05 |
| Bipolar disorders |
2.42 |
1.47 |
3.36 |
0.48 |
5.08e-07 |
| Female |
0.32 |
0.07 |
0.56 |
0.12 |
0.01 |
| Non-binary/Self-defined |
0.78 |
0.07 |
1.49 |
0.36 |
0.03 |
| Age |
-80.86 |
-91.48 |
-70.25 |
5.42 |
5.90e-50 |
| Age^2 |
-3.91 |
-14.34 |
6.52 |
5.32 |
0.46 |
| Mixed or multiple ethnic origins |
0.08 |
-0.56 |
0.72 |
0.33 |
0.81 |
| Asian or Asian British |
-0.77 |
-1.82 |
0.27 |
0.53 |
0.15 |
| African or African British |
-0.26 |
-1.93 |
1.40 |
0.85 |
0.76 |
| Other ethnicity |
0.16 |
-0.79 |
1.12 |
0.49 |
0.74 |
| Key worker |
-0.59 |
-0.78 |
-0.40 |
0.10 |
1.71e-09 |
| Time difference: Lockdown to baseline |
0.08 |
0.02 |
0.14 |
0.03 |
0.007 |
| 12024 |
0.02 |
0.02 |
41.62 |
1.65e-50 |
6 |
Model 2b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.52 |
1.72 |
3.33 |
0.41 |
7.99e-10 |
| phq.sum_score_prepan |
0.57 |
0.55 |
0.58 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
1.26 |
0.63 |
1.89 |
0.32 |
9.04e-05 |
| Only depressive disorder |
0.84 |
0.16 |
1.52 |
0.35 |
0.02 |
| Only anxiety disorder |
0.26 |
-0.46 |
0.97 |
0.36 |
0.48 |
| Eating disorders |
0.93 |
0.62 |
1.24 |
0.16 |
2.88e-09 |
| OCDs |
0.56 |
0.28 |
0.85 |
0.15 |
1.16e-04 |
| Psychotic and bipolar disorder |
-0.46 |
-1.31 |
0.38 |
0.43 |
0.28 |
| Only psychotic disorder |
0.27 |
-0.42 |
0.97 |
0.35 |
0.44 |
| Only bipolar disorder |
0.31 |
-0.11 |
0.73 |
0.21 |
0.14 |
| PTSD |
0.67 |
0.40 |
0.94 |
0.14 |
1.32e-06 |
| ASD |
0.74 |
0.18 |
1.30 |
0.29 |
0.009 |
| ADHD |
0.28 |
-0.47 |
1.04 |
0.39 |
0.47 |
| Personality disorder |
1.11 |
0.74 |
1.49 |
0.19 |
6.87e-09 |
| Female |
0.10 |
-0.16 |
0.35 |
0.13 |
0.46 |
| Non-binary/Self-defined |
0.26 |
-0.47 |
0.98 |
0.37 |
0.48 |
| Age |
-74.08 |
-85.11 |
-63.04 |
5.63 |
3.00e-39 |
| Age^2 |
-0.16 |
-10.98 |
10.66 |
5.52 |
0.98 |
| Mixed or multiple ethnic origins |
0.05 |
-0.61 |
0.71 |
0.34 |
0.87 |
| Asian or Asian British |
-0.66 |
-1.73 |
0.40 |
0.54 |
0.22 |
| African or African British |
-0.59 |
-2.29 |
1.10 |
0.87 |
0.49 |
| Other ethnicity |
0.20 |
-0.79 |
1.20 |
0.51 |
0.69 |
| Key worker |
-0.46 |
-0.65 |
-0.26 |
0.10 |
6.81e-06 |
| Time difference: Lockdown to baseline |
0.07 |
0.01 |
0.13 |
0.03 |
0.02 |
| 12024 |
0.02 |
0.02 |
41.62 |
1.65e-50 |
6 |
PHQ prepan: sensitivity
Regression: Absolute scores
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline #### Subset of participants 3 months prior to pandemic
| Intercept |
2.20 |
-0.23 |
4.63 |
1.24 |
0.08 |
| phq.sum_score_prepan |
0.64 |
0.59 |
0.69 |
0.03 |
1.62e-99 |
| Depressive and anxiety disorder |
0.09 |
-1.58 |
1.76 |
0.85 |
0.92 |
| Only depressive disorder |
-0.11 |
-1.91 |
1.69 |
0.92 |
0.91 |
| Only anxiety disorder |
-0.15 |
-2.15 |
1.85 |
1.02 |
0.88 |
| Eating disorders |
1.14 |
0.09 |
2.20 |
0.54 |
0.03 |
| OCDs |
0.04 |
-1.02 |
1.11 |
0.54 |
0.94 |
| Psychotic and bipolar disorder |
-0.82 |
-3.46 |
1.83 |
1.35 |
0.55 |
| Only psychotic disorder |
-0.84 |
-3.47 |
1.78 |
1.34 |
0.53 |
| Only bipolar disorder |
-0.13 |
-1.80 |
1.53 |
0.85 |
0.88 |
| PTSD |
1.41 |
0.43 |
2.39 |
0.50 |
0.005 |
| ASD |
2.51 |
0.66 |
4.37 |
0.94 |
0.008 |
| ADHD |
-1.75 |
-4.34 |
0.83 |
1.32 |
0.18 |
| Personality disorder |
0.46 |
-0.87 |
1.79 |
0.68 |
0.49 |
| Female |
0.41 |
-0.46 |
1.28 |
0.44 |
0.35 |
| Non-binary/Self-defined |
0.17 |
-3.00 |
3.33 |
1.61 |
0.92 |
| age_category_collapsed_reordered16-18 |
1.56 |
-0.35 |
3.47 |
0.97 |
0.11 |
| 19-25 years |
0.28 |
-1.00 |
1.56 |
0.65 |
0.67 |
| 36-45 years |
0.24 |
-0.83 |
1.31 |
0.55 |
0.66 |
| 46-55 years |
-0.75 |
-1.82 |
0.32 |
0.55 |
0.17 |
| 56-65 years |
-0.06 |
-1.19 |
1.06 |
0.57 |
0.91 |
| 66-70 years |
-0.89 |
-2.89 |
1.11 |
1.02 |
0.38 |
| 71-75 years |
-2.96 |
-5.81 |
-0.11 |
1.45 |
0.04 |
| 76+ years |
1.21 |
-2.30 |
4.72 |
1.79 |
0.50 |
| Mixed or multiple ethnic origins |
-1.60 |
-3.90 |
0.70 |
1.17 |
0.17 |
| Asian or Asian British |
-0.15 |
-3.81 |
3.51 |
1.86 |
0.94 |
| African or African British |
-2.48 |
-6.81 |
1.85 |
2.21 |
0.26 |
| Other ethnicity |
-2.58 |
-6.87 |
1.71 |
2.19 |
0.24 |
| Key worker |
-0.18 |
-0.91 |
0.56 |
0.37 |
0.64 |
| Time difference: Lockdown to baseline |
0.06 |
-0.12 |
0.23 |
0.09 |
0.52 |
| 830 |
0.02 |
0.01 |
2.93 |
0.008 |
6 |
Subset of participants 6 months prior to pandemic
| Intercept |
1.94 |
0.22 |
3.66 |
0.88 |
0.03 |
| phq.sum_score_prepan |
0.62 |
0.59 |
0.66 |
0.02 |
1.08e-190 |
| Depressive and anxiety disorder |
0.57 |
-0.55 |
1.68 |
0.57 |
0.32 |
| Only depressive disorder |
0.29 |
-0.93 |
1.52 |
0.62 |
0.64 |
| Only anxiety disorder |
-0.13 |
-1.47 |
1.21 |
0.69 |
0.85 |
| Eating disorders |
1.35 |
0.58 |
2.13 |
0.39 |
5.91e-04 |
| OCDs |
0.40 |
-0.33 |
1.12 |
0.37 |
0.28 |
| Psychotic and bipolar disorder |
-1.39 |
-3.53 |
0.75 |
1.09 |
0.20 |
| Only psychotic disorder |
-0.05 |
-1.65 |
1.55 |
0.81 |
0.95 |
| Only bipolar disorder |
-0.02 |
-1.11 |
1.07 |
0.55 |
0.97 |
| PTSD |
1.33 |
0.64 |
2.03 |
0.35 |
1.59e-04 |
| ASD |
1.25 |
-0.15 |
2.65 |
0.72 |
0.08 |
| ADHD |
-1.00 |
-2.66 |
0.65 |
0.84 |
0.24 |
| Personality disorder |
1.35 |
0.40 |
2.29 |
0.48 |
0.005 |
| Female |
0.30 |
-0.32 |
0.92 |
0.32 |
0.34 |
| Non-binary/Self-defined |
0.53 |
-1.45 |
2.50 |
1.01 |
0.60 |
| age_category_collapsed_reordered16-18 |
1.98 |
0.79 |
3.17 |
0.61 |
0.001 |
| 19-25 years |
0.29 |
-0.61 |
1.20 |
0.46 |
0.53 |
| 36-45 years |
-0.38 |
-1.15 |
0.39 |
0.39 |
0.33 |
| 46-55 years |
-0.82 |
-1.58 |
-0.05 |
0.39 |
0.04 |
| 56-65 years |
-0.47 |
-1.29 |
0.34 |
0.41 |
0.25 |
| 66-70 years |
-1.28 |
-2.66 |
0.09 |
0.70 |
0.07 |
| 71-75 years |
-2.98 |
-4.65 |
-1.31 |
0.85 |
4.65e-04 |
| 76+ years |
-0.07 |
-2.60 |
2.45 |
1.29 |
0.95 |
| Mixed or multiple ethnic origins |
-0.84 |
-2.44 |
0.76 |
0.82 |
0.30 |
| Asian or Asian British |
-1.05 |
-3.18 |
1.07 |
1.09 |
0.33 |
| African or African British |
-1.68 |
-5.27 |
1.91 |
1.83 |
0.36 |
| Other ethnicity |
-1.30 |
-3.92 |
1.33 |
1.34 |
0.33 |
| Key worker |
-0.23 |
-0.74 |
0.27 |
0.26 |
0.37 |
| Time difference: Lockdown to baseline |
0.09 |
-0.04 |
0.23 |
0.07 |
0.19 |
| 1636 |
0.02 |
0.02 |
5.43 |
1.42e-05 |
6 |
Subset of participants 9 months prior to pandemic
| Intercept |
3.03 |
1.63 |
4.44 |
0.72 |
2.41e-05 |
| phq.sum_score_prepan |
0.60 |
0.57 |
0.63 |
0.01 |
8.22e-281 |
| Depressive and anxiety disorder |
0.78 |
-0.14 |
1.69 |
0.47 |
0.10 |
| Only depressive disorder |
0.51 |
-0.48 |
1.50 |
0.51 |
0.31 |
| Only anxiety disorder |
-0.30 |
-1.41 |
0.81 |
0.57 |
0.60 |
| Eating disorders |
1.40 |
0.78 |
2.02 |
0.32 |
9.09e-06 |
| OCDs |
0.38 |
-0.21 |
0.96 |
0.30 |
0.20 |
| Psychotic and bipolar disorder |
-0.73 |
-2.35 |
0.88 |
0.82 |
0.37 |
| Only psychotic disorder |
0.55 |
-0.74 |
1.84 |
0.66 |
0.40 |
| Only bipolar disorder |
0.40 |
-0.46 |
1.27 |
0.44 |
0.36 |
| PTSD |
1.17 |
0.63 |
1.72 |
0.28 |
2.57e-05 |
| ASD |
0.79 |
-0.34 |
1.93 |
0.58 |
0.17 |
| ADHD |
-0.86 |
-2.27 |
0.54 |
0.72 |
0.23 |
| Personality disorder |
1.35 |
0.60 |
2.10 |
0.38 |
4.41e-04 |
| Female |
-0.08 |
-0.57 |
0.41 |
0.25 |
0.75 |
| Non-binary/Self-defined |
0.11 |
-1.40 |
1.63 |
0.77 |
0.88 |
| age_category_collapsed_reordered16-18 |
2.11 |
1.04 |
3.18 |
0.54 |
1.09e-04 |
| 19-25 years |
0.37 |
-0.37 |
1.11 |
0.38 |
0.33 |
| 36-45 years |
-0.19 |
-0.80 |
0.42 |
0.31 |
0.54 |
| 46-55 years |
-0.43 |
-1.02 |
0.16 |
0.30 |
0.15 |
| 56-65 years |
-0.68 |
-1.32 |
-0.05 |
0.33 |
0.04 |
| 66-70 years |
-1.05 |
-2.10 |
-0.01 |
0.53 |
0.05 |
| 71-75 years |
-2.31 |
-3.60 |
-1.02 |
0.66 |
4.58e-04 |
| 76+ years |
-0.53 |
-2.72 |
1.65 |
1.11 |
0.63 |
| Mixed or multiple ethnic origins |
0.01 |
-1.39 |
1.42 |
0.72 |
0.98 |
| Asian or Asian British |
-1.04 |
-2.77 |
0.70 |
0.88 |
0.24 |
| African or African British |
-0.03 |
-2.96 |
2.91 |
1.50 |
0.99 |
| Other ethnicity |
-1.26 |
-3.05 |
0.52 |
0.91 |
0.16 |
| Key worker |
-0.37 |
-0.78 |
0.03 |
0.21 |
0.07 |
| Time difference: Lockdown to baseline |
0.00 |
-0.11 |
0.11 |
0.06 |
0.95 |
| 2714 |
0.03 |
0.03 |
13.11 |
1.12e-14 |
6 |
PHQ retro
Regression: Change scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
3.04 |
2.90 |
3.18 |
0.07 |
0.00e+00 |
| Anxiety disorders |
0.64 |
0.32 |
0.96 |
0.16 |
8.21e-05 |
| Eating disorders |
0.55 |
-0.42 |
1.52 |
0.50 |
0.27 |
| OCDs |
1.05 |
0.28 |
1.82 |
0.39 |
0.008 |
| PTSD |
1.29 |
0.51 |
2.06 |
0.39 |
0.001 |
| Depressive disorders |
0.94 |
0.77 |
1.11 |
0.09 |
4.17e-27 |
| Bipolar disorders |
0.86 |
0.48 |
1.23 |
0.19 |
9.72e-06 |
| 20515 |
0.01 |
0.01 |
20.21 |
1.05e-23 |
6 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
3.08 |
2.95 |
3.22 |
0.07 |
0.00e+00 |
| Depressive and anxiety disorder |
0.74 |
0.56 |
0.92 |
0.09 |
1.08e-15 |
| Only depressive disorder |
0.41 |
0.17 |
0.65 |
0.12 |
8.67e-04 |
| Only anxiety disorder |
0.59 |
0.29 |
0.88 |
0.15 |
9.74e-05 |
| Eating disorders |
0.66 |
0.37 |
0.94 |
0.14 |
5.62e-06 |
| OCDs |
0.19 |
-0.08 |
0.47 |
0.14 |
0.16 |
| Psychotic and bipolar disorder |
-0.92 |
-1.71 |
-0.14 |
0.40 |
0.02 |
| Only psychotic disorder |
-0.55 |
-1.23 |
0.13 |
0.35 |
0.11 |
| Only bipolar disorder |
-0.09 |
-0.51 |
0.34 |
0.22 |
0.69 |
| PTSD |
0.56 |
0.30 |
0.81 |
0.13 |
1.57e-05 |
| ASD |
0.51 |
0.02 |
1.00 |
0.25 |
0.04 |
| ADHD |
0.08 |
-0.57 |
0.73 |
0.33 |
0.80 |
| Personality disorder |
0.29 |
-0.07 |
0.65 |
0.18 |
0.11 |
| 20515 |
0.01 |
0.01 |
20.21 |
1.05e-23 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
4.53 |
4.16 |
4.90 |
0.19 |
4.74e-127 |
| Anxiety disorders |
0.23 |
-0.10 |
0.57 |
0.17 |
0.17 |
| Eating disorders |
0.01 |
-0.99 |
1.01 |
0.51 |
0.98 |
| OCDs |
0.29 |
-0.50 |
1.07 |
0.40 |
0.48 |
| PTSD |
0.95 |
0.15 |
1.75 |
0.41 |
0.02 |
| Depressive disorders |
0.70 |
0.51 |
0.89 |
0.10 |
3.78e-13 |
| Bipolar disorders |
0.68 |
0.29 |
1.08 |
0.20 |
6.16e-04 |
| Female |
0.74 |
0.55 |
0.94 |
0.10 |
8.94e-14 |
| Non-binary/Self-defined |
0.14 |
-0.52 |
0.80 |
0.34 |
0.67 |
| age_category_collapsed_reordered16-18 |
1.35 |
0.93 |
1.77 |
0.22 |
4.11e-10 |
| 19-25 years |
0.77 |
0.48 |
1.07 |
0.15 |
2.48e-07 |
| 36-45 years |
-0.47 |
-0.72 |
-0.21 |
0.13 |
3.52e-04 |
| 46-55 years |
-0.48 |
-0.72 |
-0.23 |
0.12 |
1.14e-04 |
| 56-65 years |
-0.63 |
-0.87 |
-0.38 |
0.13 |
5.72e-07 |
| 66-70 years |
-1.04 |
-1.40 |
-0.69 |
0.18 |
8.63e-09 |
| 71-75 years |
-1.12 |
-1.56 |
-0.68 |
0.22 |
5.65e-07 |
| 76+ years |
-1.35 |
-2.10 |
-0.59 |
0.38 |
4.61e-04 |
| Mixed or multiple ethnic origins |
-0.22 |
-0.76 |
0.32 |
0.28 |
0.42 |
| Asian or Asian British |
-0.28 |
-0.98 |
0.42 |
0.36 |
0.43 |
| African or African British |
-0.60 |
-1.88 |
0.68 |
0.65 |
0.36 |
| Other ethnicity |
-0.43 |
-1.33 |
0.47 |
0.46 |
0.35 |
| Time difference: Lockdown to baseline |
-0.24 |
-0.27 |
-0.20 |
0.02 |
1.96e-37 |
| 20515 |
0.01 |
0.01 |
20.21 |
1.05e-23 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
4.36 |
3.98 |
4.73 |
0.19 |
3.49e-113 |
| Depressive and anxiety disorder |
0.58 |
0.38 |
0.78 |
0.10 |
1.04e-08 |
| Only depressive disorder |
0.45 |
0.20 |
0.71 |
0.13 |
5.60e-04 |
| Only anxiety disorder |
0.25 |
-0.06 |
0.57 |
0.16 |
0.11 |
| Eating disorders |
0.43 |
0.14 |
0.72 |
0.15 |
0.003 |
| OCDs |
0.04 |
-0.23 |
0.32 |
0.14 |
0.76 |
| Psychotic and bipolar disorder |
-0.68 |
-1.47 |
0.11 |
0.40 |
0.09 |
| Only psychotic disorder |
-0.42 |
-1.11 |
0.27 |
0.35 |
0.23 |
| Only bipolar disorder |
0.05 |
-0.38 |
0.48 |
0.22 |
0.83 |
| PTSD |
0.57 |
0.31 |
0.83 |
0.13 |
1.58e-05 |
| ASD |
0.19 |
-0.31 |
0.69 |
0.26 |
0.45 |
| ADHD |
0.00 |
-0.67 |
0.66 |
0.34 |
0.99 |
| Personality disorder |
0.25 |
-0.11 |
0.62 |
0.19 |
0.18 |
| Female |
0.68 |
0.48 |
0.88 |
0.10 |
1.92e-11 |
| Non-binary/Self-defined |
0.03 |
-0.64 |
0.71 |
0.34 |
0.92 |
| age_category_collapsed_reordered16-18 |
1.59 |
1.17 |
2.02 |
0.22 |
1.43e-13 |
| 19-25 years |
0.85 |
0.55 |
1.14 |
0.15 |
2.51e-08 |
| 36-45 years |
-0.42 |
-0.68 |
-0.16 |
0.13 |
0.002 |
| 46-55 years |
-0.41 |
-0.66 |
-0.17 |
0.13 |
0.001 |
| 56-65 years |
-0.50 |
-0.75 |
-0.24 |
0.13 |
1.22e-04 |
| 66-70 years |
-0.75 |
-1.12 |
-0.38 |
0.19 |
6.96e-05 |
| 71-75 years |
-0.88 |
-1.34 |
-0.43 |
0.23 |
1.41e-04 |
| 76+ years |
-1.14 |
-1.90 |
-0.38 |
0.39 |
0.003 |
| Mixed or multiple ethnic origins |
-0.11 |
-0.66 |
0.44 |
0.28 |
0.69 |
| Asian or Asian British |
0.00 |
-0.69 |
0.68 |
0.35 |
0.99 |
| African or African British |
-0.72 |
-1.99 |
0.54 |
0.64 |
0.26 |
| Other ethnicity |
-0.22 |
-1.14 |
0.69 |
0.47 |
0.63 |
| Key worker |
0.26 |
0.09 |
0.42 |
0.08 |
0.002 |
| Time difference: Lockdown to baseline |
-0.24 |
-0.27 |
-0.20 |
0.02 |
9.61e-37 |
| 20515 |
0.01 |
0.01 |
20.21 |
1.05e-23 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.54 |
2.12 |
2.96 |
0.21 |
1.17e-32 |
| Anxiety disorders |
0.27 |
-0.15 |
0.69 |
0.21 |
0.21 |
| Eating disorders |
0.16 |
-1.05 |
1.38 |
0.62 |
0.79 |
| OCDs |
0.16 |
-0.84 |
1.15 |
0.51 |
0.76 |
| PTSD |
1.00 |
-0.17 |
2.17 |
0.60 |
0.09 |
| Depressive disorders |
0.93 |
0.71 |
1.16 |
0.12 |
1.32e-15 |
| Bipolar disorders |
0.93 |
0.49 |
1.36 |
0.22 |
3.10e-05 |
| Female |
0.50 |
0.28 |
0.72 |
0.11 |
5.73e-06 |
| Non-binary/Self-defined |
-0.51 |
-1.23 |
0.21 |
0.37 |
0.17 |
| Age |
-94.43 |
-109.79 |
-79.08 |
7.83 |
2.67e-33 |
| Age^2 |
8.59 |
-5.67 |
22.85 |
7.27 |
0.24 |
| Mixed or multiple ethnic origins |
-0.34 |
-0.95 |
0.28 |
0.31 |
0.28 |
| Asian or Asian British |
-0.54 |
-1.41 |
0.33 |
0.44 |
0.22 |
| African or African British |
-0.27 |
-1.74 |
1.20 |
0.75 |
0.72 |
| Other ethnicity |
-0.22 |
-1.27 |
0.83 |
0.54 |
0.68 |
| Time difference: Lockdown to baseline |
-0.08 |
-0.13 |
-0.03 |
0.02 |
0.001 |
| 14828 |
0.01 |
0.01 |
31.26 |
1.47e-37 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.51 |
2.09 |
2.93 |
0.22 |
3.78e-31 |
| Depressive and anxiety disorder |
0.84 |
0.60 |
1.07 |
0.12 |
4.07e-12 |
| Only depressive disorder |
0.70 |
0.40 |
1.01 |
0.16 |
7.08e-06 |
| Only anxiety disorder |
0.28 |
-0.11 |
0.66 |
0.20 |
0.16 |
| Eating disorders |
0.36 |
0.04 |
0.68 |
0.16 |
0.03 |
| OCDs |
-0.10 |
-0.40 |
0.21 |
0.16 |
0.53 |
| Psychotic and bipolar disorder |
-0.54 |
-1.46 |
0.38 |
0.47 |
0.25 |
| Only psychotic disorder |
-0.26 |
-1.01 |
0.49 |
0.38 |
0.50 |
| Only bipolar disorder |
0.01 |
-0.45 |
0.47 |
0.23 |
0.96 |
| PTSD |
0.64 |
0.35 |
0.93 |
0.15 |
1.51e-05 |
| ASD |
-0.07 |
-0.65 |
0.52 |
0.30 |
0.83 |
| ADHD |
0.09 |
-0.70 |
0.88 |
0.40 |
0.82 |
| Personality disorder |
0.31 |
-0.09 |
0.72 |
0.21 |
0.13 |
| Female |
0.44 |
0.22 |
0.66 |
0.11 |
9.16e-05 |
| Non-binary/Self-defined |
-0.65 |
-1.39 |
0.08 |
0.38 |
0.08 |
| Age |
-86.23 |
-102.36 |
-70.11 |
8.23 |
1.32e-25 |
| Age^2 |
16.24 |
1.43 |
31.06 |
7.56 |
0.03 |
| Mixed or multiple ethnic origins |
-0.28 |
-0.91 |
0.34 |
0.32 |
0.37 |
| Asian or Asian British |
-0.41 |
-1.27 |
0.45 |
0.44 |
0.35 |
| African or African British |
-0.55 |
-2.01 |
0.92 |
0.75 |
0.47 |
| Other ethnicity |
-0.08 |
-1.15 |
1.00 |
0.55 |
0.89 |
| Key worker |
0.27 |
0.09 |
0.45 |
0.09 |
0.004 |
| Time difference: Lockdown to baseline |
-0.08 |
-0.13 |
-0.03 |
0.02 |
7.64e-04 |
| 14828 |
0.01 |
0.01 |
31.26 |
1.47e-37 |
6 |
Regression: Absolute scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
1.80 |
1.72 |
1.88 |
0.04 |
0.00e+00 |
| phq.sum_score_retro |
0.77 |
0.76 |
0.78 |
0.01 |
0.00e+00 |
| Anxiety disorders |
1.88 |
1.66 |
2.11 |
0.11 |
1.22e-61 |
| Eating disorders |
2.02 |
1.31 |
2.74 |
0.36 |
2.84e-08 |
| OCDs |
2.88 |
2.31 |
3.46 |
0.30 |
1.53e-22 |
| PTSD |
2.65 |
2.10 |
3.21 |
0.28 |
1.15e-20 |
| Depressive disorders |
3.15 |
3.03 |
3.27 |
0.06 |
0.00e+00 |
| Bipolar disorders |
3.78 |
3.49 |
4.07 |
0.15 |
8.33e-140 |
| 30794 |
0.59 |
0.59 |
6280.68 |
0.00e+00 |
7 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
1.98 |
1.90 |
2.06 |
0.04 |
0.00e+00 |
| phq.sum_score_retro |
0.74 |
0.73 |
0.75 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
3.16 |
3.03 |
3.29 |
0.07 |
0.00e+00 |
| Only depressive disorder |
1.71 |
1.55 |
1.87 |
0.08 |
1.30e-95 |
| Only anxiety disorder |
1.86 |
1.65 |
2.06 |
0.10 |
2.39e-70 |
| Eating disorders |
1.06 |
0.85 |
1.28 |
0.11 |
4.35e-22 |
| OCDs |
0.68 |
0.47 |
0.89 |
0.11 |
1.39e-10 |
| Psychotic and bipolar disorder |
-0.44 |
-1.04 |
0.15 |
0.30 |
0.14 |
| Only psychotic disorder |
-0.09 |
-0.60 |
0.42 |
0.26 |
0.73 |
| Only bipolar disorder |
0.41 |
0.09 |
0.73 |
0.16 |
0.01 |
| PTSD |
0.87 |
0.68 |
1.07 |
0.10 |
3.33e-19 |
| ASD |
1.20 |
0.82 |
1.57 |
0.19 |
3.39e-10 |
| ADHD |
0.61 |
0.11 |
1.10 |
0.25 |
0.02 |
| Personality disorder |
0.99 |
0.71 |
1.26 |
0.14 |
2.18e-12 |
| 30959 |
0.28 |
0.28 |
2029.98 |
0.00e+00 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
4.19 |
3.92 |
4.45 |
0.14 |
3.76e-206 |
| phq.sum_score_retro |
0.71 |
0.70 |
0.72 |
0.01 |
0.00e+00 |
| Anxiety disorders |
1.19 |
0.96 |
1.42 |
0.12 |
2.19e-23 |
| Eating disorders |
1.09 |
0.36 |
1.81 |
0.37 |
0.003 |
| OCDs |
1.47 |
0.88 |
2.06 |
0.30 |
9.93e-07 |
| PTSD |
2.16 |
1.58 |
2.73 |
0.29 |
2.71e-13 |
| Depressive disorders |
2.72 |
2.59 |
2.85 |
0.07 |
0.00e+00 |
| Bipolar disorders |
3.49 |
3.19 |
3.79 |
0.15 |
3.14e-115 |
| Female |
0.80 |
0.67 |
0.92 |
0.06 |
1.35e-35 |
| Non-binary/Self-defined |
0.86 |
0.36 |
1.36 |
0.25 |
6.80e-04 |
| age_category_collapsed_reordered16-18 |
2.61 |
2.28 |
2.94 |
0.17 |
4.62e-53 |
| 19-25 years |
1.20 |
0.98 |
1.43 |
0.12 |
4.25e-25 |
| 36-45 years |
-0.62 |
-0.81 |
-0.43 |
0.10 |
2.37e-10 |
| 46-55 years |
-0.85 |
-1.03 |
-0.67 |
0.09 |
5.88e-21 |
| 56-65 years |
-1.43 |
-1.61 |
-1.25 |
0.09 |
5.93e-56 |
| 66-70 years |
-2.14 |
-2.37 |
-1.91 |
0.12 |
1.58e-73 |
| 71-75 years |
-2.28 |
-2.55 |
-2.02 |
0.13 |
2.12e-64 |
| 76+ years |
-2.33 |
-2.73 |
-1.94 |
0.20 |
1.31e-30 |
| Mixed or multiple ethnic origins |
-0.01 |
-0.40 |
0.39 |
0.20 |
0.97 |
| Asian or Asian British |
-0.28 |
-0.76 |
0.21 |
0.25 |
0.26 |
| African or African British |
-0.39 |
-1.27 |
0.50 |
0.45 |
0.39 |
| Other ethnicity |
0.19 |
-0.50 |
0.88 |
0.35 |
0.59 |
| Key worker |
-0.13 |
-0.25 |
-0.02 |
0.06 |
0.02 |
| Time difference: Lockdown to baseline |
-0.21 |
-0.24 |
-0.19 |
0.01 |
3.54e-56 |
| 30959 |
0.28 |
0.28 |
2029.98 |
0.00e+00 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
4.15 |
3.88 |
4.41 |
0.13 |
2.40e-205 |
| phq.sum_score_retro |
0.68 |
0.67 |
0.69 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
2.74 |
2.60 |
2.89 |
0.07 |
1.04e-296 |
| Only depressive disorder |
1.71 |
1.54 |
1.88 |
0.09 |
1.70e-84 |
| Only anxiety disorder |
1.21 |
0.99 |
1.42 |
0.11 |
4.98e-28 |
| Eating disorders |
0.75 |
0.54 |
0.97 |
0.11 |
1.06e-11 |
| OCDs |
0.44 |
0.23 |
0.65 |
0.11 |
3.16e-05 |
| Psychotic and bipolar disorder |
-0.15 |
-0.74 |
0.44 |
0.30 |
0.61 |
| Only psychotic disorder |
0.12 |
-0.39 |
0.63 |
0.26 |
0.64 |
| Only bipolar disorder |
0.65 |
0.33 |
0.97 |
0.16 |
7.93e-05 |
| PTSD |
0.97 |
0.78 |
1.17 |
0.10 |
7.29e-23 |
| ASD |
0.62 |
0.24 |
1.00 |
0.19 |
0.001 |
| ADHD |
0.28 |
-0.22 |
0.78 |
0.25 |
0.27 |
| Personality disorder |
1.03 |
0.75 |
1.30 |
0.14 |
3.60e-13 |
| Female |
0.75 |
0.62 |
0.87 |
0.06 |
1.30e-31 |
| Non-binary/Self-defined |
0.49 |
-0.01 |
0.98 |
0.25 |
0.06 |
| age_category_collapsed_reordered16-18 |
2.99 |
2.67 |
3.32 |
0.17 |
2.89e-72 |
| 19-25 years |
1.25 |
1.02 |
1.47 |
0.12 |
7.36e-27 |
| 36-45 years |
-0.53 |
-0.72 |
-0.34 |
0.10 |
7.52e-08 |
| 46-55 years |
-0.69 |
-0.87 |
-0.52 |
0.09 |
2.93e-14 |
| 56-65 years |
-1.19 |
-1.37 |
-1.01 |
0.09 |
1.11e-38 |
| 66-70 years |
-1.82 |
-2.05 |
-1.59 |
0.12 |
1.17e-53 |
| 71-75 years |
-1.99 |
-2.25 |
-1.72 |
0.13 |
2.64e-49 |
| 76+ years |
-2.03 |
-2.42 |
-1.64 |
0.20 |
2.82e-24 |
| Mixed or multiple ethnic origins |
0.05 |
-0.35 |
0.45 |
0.20 |
0.80 |
| Asian or Asian British |
0.03 |
-0.44 |
0.50 |
0.24 |
0.90 |
| African or African British |
-0.42 |
-1.28 |
0.45 |
0.44 |
0.35 |
| Other ethnicity |
0.36 |
-0.34 |
1.06 |
0.36 |
0.31 |
| Key worker |
-0.05 |
-0.16 |
0.07 |
0.06 |
0.44 |
| Time difference: Lockdown to baseline |
-0.22 |
-0.24 |
-0.19 |
0.01 |
1.48e-59 |
| 30959 |
0.28 |
0.28 |
2029.98 |
0.00e+00 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
1.65 |
1.38 |
1.93 |
0.14 |
6.97e-33 |
| phq.sum_score_retro |
0.72 |
0.70 |
0.73 |
0.01 |
0.00e+00 |
| Anxiety disorders |
1.09 |
0.82 |
1.36 |
0.14 |
2.68e-15 |
| Eating disorders |
1.14 |
0.32 |
1.96 |
0.42 |
0.006 |
| OCDs |
1.69 |
0.98 |
2.41 |
0.36 |
3.40e-06 |
| PTSD |
1.90 |
1.15 |
2.65 |
0.38 |
7.24e-07 |
| Depressive disorders |
2.82 |
2.67 |
2.97 |
0.07 |
9.31e-302 |
| Bipolar disorders |
3.58 |
3.27 |
3.90 |
0.16 |
2.80e-109 |
| Female |
0.50 |
0.37 |
0.63 |
0.07 |
3.21e-14 |
| Non-binary/Self-defined |
0.31 |
-0.21 |
0.83 |
0.26 |
0.25 |
| Age |
-155.11 |
-165.11 |
-145.10 |
5.10 |
1.61e-198 |
| Age^2 |
13.96 |
5.07 |
22.84 |
4.53 |
0.002 |
| Mixed or multiple ethnic origins |
-0.08 |
-0.51 |
0.34 |
0.22 |
0.71 |
| Asian or Asian British |
-0.24 |
-0.80 |
0.32 |
0.29 |
0.41 |
| African or African British |
-0.23 |
-1.14 |
0.69 |
0.47 |
0.63 |
| Other ethnicity |
0.36 |
-0.43 |
1.14 |
0.40 |
0.37 |
| Key worker |
-0.14 |
-0.26 |
-0.02 |
0.06 |
0.03 |
| Time difference: Lockdown to baseline |
-0.01 |
-0.05 |
0.02 |
0.02 |
0.41 |
| 23649 |
0.34 |
0.34 |
2058.71 |
0.00e+00 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
1.71 |
1.44 |
1.98 |
0.14 |
1.32e-35 |
| phq.sum_score_retro |
0.69 |
0.68 |
0.70 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
2.90 |
2.74 |
3.06 |
0.08 |
1.35e-276 |
| Only depressive disorder |
1.83 |
1.64 |
2.02 |
0.10 |
6.00e-80 |
| Only anxiety disorder |
1.22 |
0.98 |
1.47 |
0.13 |
3.79e-22 |
| Eating disorders |
0.78 |
0.55 |
1.01 |
0.12 |
2.25e-11 |
| OCDs |
0.37 |
0.14 |
0.59 |
0.11 |
0.001 |
| Psychotic and bipolar disorder |
-0.12 |
-0.78 |
0.55 |
0.34 |
0.73 |
| Only psychotic disorder |
0.24 |
-0.30 |
0.78 |
0.27 |
0.39 |
| Only bipolar disorder |
0.61 |
0.28 |
0.94 |
0.17 |
2.75e-04 |
| PTSD |
0.96 |
0.76 |
1.17 |
0.10 |
5.13e-20 |
| ASD |
0.49 |
0.06 |
0.91 |
0.22 |
0.03 |
| ADHD |
0.31 |
-0.26 |
0.88 |
0.29 |
0.28 |
| Personality disorder |
0.96 |
0.68 |
1.25 |
0.15 |
6.37e-11 |
| Female |
0.43 |
0.30 |
0.56 |
0.07 |
6.92e-11 |
| Non-binary/Self-defined |
-0.04 |
-0.56 |
0.48 |
0.26 |
0.89 |
| Age |
-140.98 |
-151.08 |
-130.87 |
5.16 |
1.02e-161 |
| Age^2 |
15.80 |
7.01 |
24.59 |
4.48 |
4.26e-04 |
| Mixed or multiple ethnic origins |
-0.08 |
-0.50 |
0.35 |
0.22 |
0.73 |
| Asian or Asian British |
-0.04 |
-0.59 |
0.50 |
0.28 |
0.88 |
| African or African British |
-0.34 |
-1.25 |
0.56 |
0.46 |
0.45 |
| Other ethnicity |
0.42 |
-0.38 |
1.21 |
0.41 |
0.30 |
| Key worker |
-0.05 |
-0.17 |
0.07 |
0.06 |
0.45 |
| Time difference: Lockdown to baseline |
-0.01 |
-0.05 |
0.02 |
0.02 |
0.41 |
| 23649 |
0.34 |
0.34 |
2058.71 |
0.00e+00 |
6 |
PHQ retro: Sensitivity
Regression: Change scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
2.75 |
1.62 |
3.89 |
0.58 |
2.08e-06 |
| Anxiety disorders |
0.64 |
-0.62 |
1.90 |
0.64 |
0.32 |
| Eating disorders |
0.84 |
-1.60 |
3.28 |
1.24 |
0.50 |
| OCDs |
0.72 |
-0.94 |
2.39 |
0.85 |
0.40 |
| PTSD |
1.21 |
-0.70 |
3.12 |
0.98 |
0.21 |
| Depressive disorders |
0.98 |
-0.17 |
2.12 |
0.58 |
0.09 |
| Bipolar disorders |
0.74 |
-0.48 |
1.97 |
0.62 |
0.23 |
| 8919 |
0.00 |
0.00 |
0.85 |
0.53 |
6 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
2.95 |
2.13 |
3.77 |
0.42 |
1.94e-12 |
| Depressive and anxiety disorder |
0.68 |
-0.16 |
1.51 |
0.42 |
0.11 |
| Only depressive disorder |
0.48 |
-0.42 |
1.38 |
0.46 |
0.30 |
| Only anxiety disorder |
0.50 |
-0.44 |
1.44 |
0.48 |
0.30 |
| Eating disorders |
0.55 |
0.16 |
0.95 |
0.20 |
0.006 |
| OCDs |
-0.12 |
-0.49 |
0.24 |
0.19 |
0.51 |
| Psychotic and bipolar disorder |
-0.74 |
-1.85 |
0.38 |
0.57 |
0.19 |
| Only psychotic disorder |
-0.46 |
-1.38 |
0.47 |
0.47 |
0.33 |
| Only bipolar disorder |
-0.27 |
-0.81 |
0.27 |
0.28 |
0.33 |
| PTSD |
0.43 |
0.09 |
0.78 |
0.18 |
0.01 |
| ASD |
0.01 |
-0.70 |
0.71 |
0.36 |
0.99 |
| ADHD |
0.27 |
-0.72 |
1.26 |
0.50 |
0.59 |
| Personality disorder |
0.38 |
-0.10 |
0.86 |
0.25 |
0.12 |
| 8919 |
0.00 |
0.00 |
0.85 |
0.53 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.97 |
1.66 |
4.27 |
0.67 |
8.24e-06 |
| Anxiety disorders |
0.52 |
-0.73 |
1.77 |
0.64 |
0.42 |
| Eating disorders |
0.56 |
-1.87 |
2.98 |
1.24 |
0.65 |
| OCDs |
0.39 |
-1.27 |
2.05 |
0.85 |
0.64 |
| PTSD |
1.22 |
-0.70 |
3.13 |
0.98 |
0.21 |
| Depressive disorders |
1.02 |
-0.12 |
2.16 |
0.58 |
0.08 |
| Bipolar disorders |
0.94 |
-0.28 |
2.17 |
0.62 |
0.13 |
| Female |
0.54 |
0.22 |
0.87 |
0.17 |
0.001 |
| Non-binary/Self-defined |
-0.40 |
-1.29 |
0.50 |
0.46 |
0.39 |
| age_category_collapsed_reordered16-18 |
0.67 |
-0.06 |
1.40 |
0.37 |
0.07 |
| 19-25 years |
0.60 |
0.21 |
1.00 |
0.20 |
0.003 |
| 36-45 years |
-0.42 |
-0.78 |
-0.06 |
0.18 |
0.02 |
| 46-55 years |
-0.47 |
-0.82 |
-0.12 |
0.18 |
0.009 |
| 56-65 years |
-1.12 |
-1.53 |
-0.72 |
0.21 |
5.27e-08 |
| 66-70 years |
-1.29 |
-2.05 |
-0.53 |
0.39 |
9.31e-04 |
| 71-75 years |
-2.13 |
-3.18 |
-1.08 |
0.54 |
7.08e-05 |
| 76+ years |
-1.91 |
-4.03 |
0.21 |
1.08 |
0.08 |
| Mixed or multiple ethnic origins |
-0.60 |
-1.39 |
0.20 |
0.41 |
0.14 |
| Asian or Asian British |
-0.85 |
-2.14 |
0.43 |
0.66 |
0.19 |
| African or African British |
-0.44 |
-2.55 |
1.67 |
1.08 |
0.68 |
| Other ethnicity |
-0.40 |
-1.61 |
0.82 |
0.62 |
0.52 |
| Time difference: Lockdown to baseline |
-0.05 |
-0.12 |
0.02 |
0.04 |
0.17 |
| 8919 |
0.00 |
0.00 |
0.85 |
0.53 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
3.08 |
2.01 |
4.15 |
0.55 |
1.94e-08 |
| Depressive and anxiety disorder |
0.76 |
-0.07 |
1.60 |
0.43 |
0.07 |
| Only depressive disorder |
0.80 |
-0.11 |
1.70 |
0.46 |
0.09 |
| Only anxiety disorder |
0.42 |
-0.52 |
1.37 |
0.48 |
0.38 |
| Eating disorders |
0.40 |
0.01 |
0.80 |
0.20 |
0.05 |
| OCDs |
-0.17 |
-0.54 |
0.19 |
0.19 |
0.36 |
| Psychotic and bipolar disorder |
-0.48 |
-1.59 |
0.63 |
0.57 |
0.40 |
| Only psychotic disorder |
-0.23 |
-1.15 |
0.70 |
0.47 |
0.63 |
| Only bipolar disorder |
-0.10 |
-0.65 |
0.44 |
0.28 |
0.71 |
| PTSD |
0.48 |
0.13 |
0.83 |
0.18 |
0.007 |
| ASD |
-0.08 |
-0.80 |
0.63 |
0.36 |
0.82 |
| ADHD |
0.28 |
-0.70 |
1.27 |
0.50 |
0.57 |
| Personality disorder |
0.32 |
-0.17 |
0.80 |
0.25 |
0.20 |
| Female |
0.49 |
0.15 |
0.84 |
0.18 |
0.005 |
| Non-binary/Self-defined |
-0.55 |
-1.47 |
0.37 |
0.47 |
0.24 |
| age_category_collapsed_reordered16-18 |
0.80 |
0.06 |
1.54 |
0.38 |
0.03 |
| 19-25 years |
0.64 |
0.23 |
1.05 |
0.21 |
0.002 |
| 36-45 years |
-0.37 |
-0.74 |
0.00 |
0.19 |
0.05 |
| 46-55 years |
-0.41 |
-0.78 |
-0.04 |
0.19 |
0.03 |
| 56-65 years |
-1.09 |
-1.51 |
-0.66 |
0.22 |
6.08e-07 |
| 66-70 years |
-1.02 |
-1.82 |
-0.22 |
0.41 |
0.01 |
| 71-75 years |
-1.72 |
-2.85 |
-0.59 |
0.58 |
0.003 |
| 76+ years |
-1.75 |
-3.99 |
0.50 |
1.15 |
0.13 |
| Mixed or multiple ethnic origins |
-0.58 |
-1.41 |
0.25 |
0.42 |
0.17 |
| Asian or Asian British |
-0.75 |
-2.07 |
0.56 |
0.67 |
0.26 |
| African or African British |
-0.89 |
-3.08 |
1.30 |
1.12 |
0.43 |
| Other ethnicity |
-0.20 |
-1.46 |
1.05 |
0.64 |
0.75 |
| Key worker |
0.24 |
-0.01 |
0.50 |
0.13 |
0.06 |
| Time difference: Lockdown to baseline |
-0.06 |
-0.14 |
0.01 |
0.04 |
0.10 |
| 8919 |
0.00 |
0.00 |
0.85 |
0.53 |
6 |
Regression: Absolute scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
4.51 |
3.57 |
5.44 |
0.48 |
3.31e-21 |
| phq.sum_score_retro |
0.66 |
0.65 |
0.68 |
0.01 |
0.00e+00 |
| Anxiety disorders |
0.17 |
-0.86 |
1.19 |
0.52 |
0.75 |
| Eating disorders |
0.88 |
-1.10 |
2.86 |
1.01 |
0.38 |
| OCDs |
1.13 |
-0.24 |
2.50 |
0.70 |
0.10 |
| PTSD |
1.04 |
-0.51 |
2.60 |
0.79 |
0.19 |
| Depressive disorders |
1.53 |
0.60 |
2.47 |
0.48 |
0.001 |
| Bipolar disorders |
2.00 |
1.00 |
3.00 |
0.51 |
9.19e-05 |
| 10344 |
0.40 |
0.40 |
995.05 |
0.00e+00 |
7 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
5.05 |
4.38 |
5.72 |
0.34 |
6.74e-49 |
| phq.sum_score_retro |
0.64 |
0.62 |
0.65 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
0.93 |
0.26 |
1.60 |
0.34 |
0.007 |
| Only depressive disorder |
0.37 |
-0.35 |
1.10 |
0.37 |
0.31 |
| Only anxiety disorder |
-0.17 |
-0.93 |
0.59 |
0.39 |
0.66 |
| Eating disorders |
0.97 |
0.65 |
1.29 |
0.16 |
2.92e-09 |
| OCDs |
0.46 |
0.16 |
0.76 |
0.15 |
0.002 |
| Psychotic and bipolar disorder |
-0.62 |
-1.52 |
0.28 |
0.46 |
0.18 |
| Only psychotic disorder |
-0.06 |
-0.80 |
0.69 |
0.38 |
0.88 |
| Only bipolar disorder |
0.26 |
-0.18 |
0.70 |
0.23 |
0.25 |
| PTSD |
0.72 |
0.44 |
1.00 |
0.14 |
4.41e-07 |
| ASD |
0.71 |
0.13 |
1.29 |
0.30 |
0.02 |
| ADHD |
0.48 |
-0.31 |
1.28 |
0.41 |
0.23 |
| Personality disorder |
1.24 |
0.85 |
1.63 |
0.20 |
5.05e-10 |
| 10375 |
0.02 |
0.02 |
38.52 |
1.50e-46 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
4.46 |
3.38 |
5.53 |
0.55 |
5.91e-16 |
| phq.sum_score_retro |
0.64 |
0.63 |
0.66 |
0.01 |
0.00e+00 |
| Anxiety disorders |
0.17 |
-0.85 |
1.19 |
0.52 |
0.74 |
| Eating disorders |
0.86 |
-1.10 |
2.81 |
1.00 |
0.39 |
| OCDs |
0.90 |
-0.46 |
2.25 |
0.69 |
0.20 |
| PTSD |
1.36 |
-0.19 |
2.90 |
0.79 |
0.09 |
| Depressive disorders |
1.83 |
0.90 |
2.76 |
0.48 |
1.20e-04 |
| Bipolar disorders |
2.47 |
1.47 |
3.47 |
0.51 |
1.34e-06 |
| Female |
0.37 |
0.10 |
0.63 |
0.13 |
0.006 |
| Non-binary/Self-defined |
0.38 |
-0.35 |
1.11 |
0.37 |
0.31 |
| age_category_collapsed_reordered16-18 |
1.87 |
1.26 |
2.49 |
0.31 |
2.66e-09 |
| 19-25 years |
0.99 |
0.66 |
1.32 |
0.17 |
4.21e-09 |
| 36-45 years |
-0.44 |
-0.73 |
-0.15 |
0.15 |
0.003 |
| 46-55 years |
-0.47 |
-0.75 |
-0.18 |
0.15 |
0.001 |
| 56-65 years |
-1.23 |
-1.56 |
-0.90 |
0.17 |
3.59e-13 |
| 66-70 years |
-2.05 |
-2.67 |
-1.44 |
0.31 |
6.56e-11 |
| 71-75 years |
-2.89 |
-3.72 |
-2.06 |
0.42 |
8.05e-12 |
| 76+ years |
-2.40 |
-4.09 |
-0.71 |
0.86 |
0.005 |
| Mixed or multiple ethnic origins |
-0.18 |
-0.84 |
0.47 |
0.34 |
0.58 |
| Asian or Asian British |
-0.38 |
-1.47 |
0.70 |
0.55 |
0.49 |
| African or African British |
0.01 |
-1.74 |
1.77 |
0.90 |
0.99 |
| Other ethnicity |
-0.07 |
-1.07 |
0.93 |
0.51 |
0.89 |
| Key worker |
-0.34 |
-0.54 |
-0.14 |
0.10 |
9.84e-04 |
| Time difference: Lockdown to baseline |
0.01 |
-0.05 |
0.07 |
0.03 |
0.80 |
| 10375 |
0.02 |
0.02 |
38.52 |
1.50e-46 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
5.17 |
4.30 |
6.04 |
0.44 |
4.18e-31 |
| phq.sum_score_retro |
0.62 |
0.60 |
0.64 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
1.13 |
0.46 |
1.80 |
0.34 |
9.16e-04 |
| Only depressive disorder |
0.84 |
0.12 |
1.56 |
0.37 |
0.02 |
| Only anxiety disorder |
-0.23 |
-0.99 |
0.52 |
0.39 |
0.55 |
| Eating disorders |
0.83 |
0.51 |
1.15 |
0.16 |
3.03e-07 |
| OCDs |
0.37 |
0.07 |
0.66 |
0.15 |
0.02 |
| Psychotic and bipolar disorder |
-0.40 |
-1.29 |
0.49 |
0.46 |
0.38 |
| Only psychotic disorder |
0.10 |
-0.64 |
0.84 |
0.38 |
0.79 |
| Only bipolar disorder |
0.44 |
0.00 |
0.88 |
0.22 |
0.05 |
| PTSD |
0.82 |
0.54 |
1.10 |
0.14 |
1.17e-08 |
| ASD |
0.38 |
-0.21 |
0.96 |
0.30 |
0.21 |
| ADHD |
0.40 |
-0.40 |
1.19 |
0.40 |
0.33 |
| Personality disorder |
1.17 |
0.78 |
1.56 |
0.20 |
3.90e-09 |
| Female |
0.17 |
-0.11 |
0.45 |
0.14 |
0.23 |
| Non-binary/Self-defined |
-0.04 |
-0.78 |
0.71 |
0.38 |
0.92 |
| age_category_collapsed_reordered16-18 |
2.00 |
1.39 |
2.62 |
0.31 |
1.51e-10 |
| 19-25 years |
1.00 |
0.67 |
1.34 |
0.17 |
5.10e-09 |
| 36-45 years |
-0.38 |
-0.68 |
-0.08 |
0.15 |
0.01 |
| 46-55 years |
-0.36 |
-0.65 |
-0.06 |
0.15 |
0.02 |
| 56-65 years |
-1.11 |
-1.45 |
-0.77 |
0.17 |
2.29e-10 |
| 66-70 years |
-1.80 |
-2.44 |
-1.17 |
0.32 |
2.73e-08 |
| 71-75 years |
-2.47 |
-3.34 |
-1.59 |
0.45 |
3.27e-08 |
| 76+ years |
-2.02 |
-3.81 |
-0.23 |
0.91 |
0.03 |
| Mixed or multiple ethnic origins |
-0.29 |
-0.97 |
0.38 |
0.34 |
0.40 |
| Asian or Asian British |
-0.24 |
-1.34 |
0.86 |
0.56 |
0.67 |
| African or African British |
-0.23 |
-2.04 |
1.58 |
0.92 |
0.80 |
| Other ethnicity |
0.01 |
-1.02 |
1.03 |
0.52 |
0.99 |
| Key worker |
-0.23 |
-0.44 |
-0.02 |
0.11 |
0.03 |
| Time difference: Lockdown to baseline |
0.00 |
-0.07 |
0.06 |
0.03 |
0.89 |
| 10375 |
0.02 |
0.02 |
38.52 |
1.50e-46 |
6 |
OCI-R baseline, not controlling for prior symptoms
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
12.34 |
11.53 |
13.16 |
0.42 |
9.64e-180 |
| Anxiety disorders |
2.31 |
0.88 |
3.74 |
0.73 |
0.002 |
| Eating disorders |
4.27 |
0.08 |
8.46 |
2.14 |
0.05 |
| OCDs |
10.28 |
7.63 |
12.93 |
1.35 |
3.09e-14 |
| PTSD |
8.12 |
5.24 |
11.00 |
1.47 |
3.29e-08 |
| Depressive disorders |
5.75 |
4.84 |
6.66 |
0.47 |
1.47e-34 |
| Bipolar disorders |
12.55 |
10.96 |
14.15 |
0.81 |
7.29e-53 |
| 5506 |
0.05 |
0.05 |
52.82 |
1.41e-63 |
6 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
13.33 |
12.63 |
14.03 |
0.36 |
1.93e-271 |
| Depressive and anxiety disorder |
2.50 |
1.63 |
3.36 |
0.44 |
1.64e-08 |
| Only depressive disorder |
-0.78 |
-1.98 |
0.41 |
0.61 |
0.20 |
| Only anxiety disorder |
0.78 |
-0.45 |
2.01 |
0.63 |
0.21 |
| Eating disorders |
0.62 |
-0.45 |
1.68 |
0.54 |
0.26 |
| OCDs |
7.47 |
6.53 |
8.41 |
0.48 |
1.21e-53 |
| Psychotic and bipolar disorder |
7.02 |
4.50 |
9.54 |
1.29 |
5.11e-08 |
| Only psychotic disorder |
4.35 |
2.05 |
6.65 |
1.17 |
2.09e-04 |
| Only bipolar disorder |
3.31 |
1.66 |
4.97 |
0.84 |
8.90e-05 |
| PTSD |
1.96 |
1.03 |
2.89 |
0.47 |
3.42e-05 |
| ASD |
9.07 |
7.38 |
10.75 |
0.86 |
7.54e-26 |
| ADHD |
2.71 |
0.39 |
5.03 |
1.18 |
0.02 |
| Personality disorder |
3.43 |
2.16 |
4.71 |
0.65 |
1.23e-07 |
| 5506 |
0.05 |
0.05 |
52.82 |
1.41e-63 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
15.38 |
13.71 |
17.04 |
0.85 |
3.30e-71 |
| Anxiety disorders |
1.84 |
0.41 |
3.28 |
0.73 |
0.01 |
| Eating disorders |
3.36 |
-0.83 |
7.55 |
2.14 |
0.12 |
| OCDs |
8.52 |
5.89 |
11.16 |
1.34 |
2.50e-10 |
| PTSD |
7.96 |
5.09 |
10.83 |
1.46 |
5.63e-08 |
| Depressive disorders |
6.01 |
5.07 |
6.96 |
0.48 |
2.87e-35 |
| Bipolar disorders |
12.47 |
10.87 |
14.08 |
0.82 |
1.51e-51 |
| Female |
-0.73 |
-1.67 |
0.21 |
0.48 |
0.13 |
| Non-binary/Self-defined |
1.61 |
-0.94 |
4.16 |
1.30 |
0.22 |
| age_category_collapsed_reordered16-18 |
7.91 |
6.31 |
9.50 |
0.81 |
3.32e-22 |
| 19-25 years |
1.66 |
0.38 |
2.95 |
0.65 |
0.01 |
| 36-45 years |
-0.49 |
-1.68 |
0.69 |
0.61 |
0.42 |
| 46-55 years |
-0.49 |
-1.58 |
0.59 |
0.55 |
0.37 |
| 56-65 years |
-1.81 |
-2.89 |
-0.72 |
0.55 |
0.001 |
| 66-70 years |
-2.72 |
-4.31 |
-1.13 |
0.81 |
7.77e-04 |
| 71-75 years |
-3.08 |
-5.02 |
-1.14 |
0.99 |
0.002 |
| 76+ years |
-4.78 |
-8.31 |
-1.25 |
1.80 |
0.008 |
| Mixed or multiple ethnic origins |
0.83 |
-1.43 |
3.09 |
1.15 |
0.47 |
| Asian or Asian British |
3.54 |
0.50 |
6.58 |
1.55 |
0.02 |
| African or African British |
2.32 |
-3.95 |
8.60 |
3.20 |
0.47 |
| Other ethnicity |
3.13 |
-0.02 |
6.28 |
1.61 |
0.05 |
| Time difference: Lockdown to baseline |
-0.41 |
-0.57 |
-0.25 |
0.08 |
4.16e-07 |
| 5506 |
0.05 |
0.05 |
52.82 |
1.41e-63 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
15.69 |
14.10 |
17.29 |
0.81 |
4.80e-80 |
| Depressive and anxiety disorder |
3.35 |
2.45 |
4.24 |
0.46 |
3.23e-13 |
| Only depressive disorder |
0.33 |
-0.87 |
1.54 |
0.62 |
0.59 |
| Only anxiety disorder |
0.91 |
-0.32 |
2.15 |
0.63 |
0.15 |
| Eating disorders |
0.25 |
-0.81 |
1.31 |
0.54 |
0.64 |
| OCDs |
7.02 |
6.09 |
7.96 |
0.48 |
2.90e-48 |
| Psychotic and bipolar disorder |
6.99 |
4.50 |
9.48 |
1.27 |
3.90e-08 |
| Only psychotic disorder |
3.92 |
1.66 |
6.18 |
1.15 |
6.92e-04 |
| Only bipolar disorder |
3.26 |
1.62 |
4.91 |
0.84 |
1.03e-04 |
| PTSD |
2.28 |
1.36 |
3.21 |
0.47 |
1.41e-06 |
| ASD |
7.51 |
5.82 |
9.21 |
0.86 |
4.75e-18 |
| ADHD |
1.65 |
-0.64 |
3.95 |
1.17 |
0.16 |
| Personality disorder |
3.37 |
2.10 |
4.63 |
0.64 |
1.79e-07 |
| Female |
-0.85 |
-1.76 |
0.06 |
0.47 |
0.07 |
| Non-binary/Self-defined |
-1.10 |
-3.60 |
1.41 |
1.28 |
0.39 |
| age_category_collapsed_reordered16-18 |
8.09 |
6.56 |
9.61 |
0.78 |
5.13e-25 |
| 19-25 years |
1.69 |
0.46 |
2.92 |
0.63 |
0.007 |
| 36-45 years |
-0.02 |
-1.18 |
1.13 |
0.59 |
0.97 |
| 46-55 years |
0.15 |
-0.91 |
1.22 |
0.54 |
0.78 |
| 56-65 years |
-0.65 |
-1.72 |
0.42 |
0.54 |
0.23 |
| 66-70 years |
-0.82 |
-2.40 |
0.77 |
0.81 |
0.31 |
| 71-75 years |
-1.92 |
-3.83 |
-0.01 |
0.97 |
0.05 |
| 76+ years |
-3.54 |
-7.04 |
-0.05 |
1.78 |
0.05 |
| Mixed or multiple ethnic origins |
0.65 |
-1.56 |
2.86 |
1.13 |
0.56 |
| Asian or Asian British |
5.19 |
2.33 |
8.06 |
1.46 |
3.88e-04 |
| African or African British |
1.28 |
-4.65 |
7.22 |
3.03 |
0.67 |
| Other ethnicity |
2.43 |
-0.68 |
5.54 |
1.59 |
0.12 |
| Key worker |
-1.06 |
-1.76 |
-0.35 |
0.36 |
0.003 |
| Time difference: Lockdown to baseline |
-0.39 |
-0.54 |
-0.24 |
0.08 |
5.53e-07 |
| 5506 |
0.05 |
0.05 |
52.82 |
1.41e-63 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
6.16 |
3.43 |
8.88 |
1.39 |
9.68e-06 |
| Anxiety disorders |
0.18 |
-2.63 |
2.99 |
1.43 |
0.90 |
| Eating disorders |
8.05 |
2.14 |
13.96 |
3.01 |
0.008 |
| OCDs |
11.14 |
6.59 |
15.69 |
2.32 |
1.68e-06 |
| PTSD |
9.60 |
3.66 |
15.54 |
3.03 |
0.002 |
| Depressive disorders |
7.16 |
5.35 |
8.98 |
0.93 |
1.58e-14 |
| Bipolar disorders |
12.37 |
9.88 |
14.85 |
1.27 |
4.57e-22 |
| Female |
-0.33 |
-1.66 |
1.00 |
0.68 |
0.63 |
| Non-binary/Self-defined |
2.76 |
-0.74 |
6.26 |
1.78 |
0.12 |
| Age |
-223.09 |
-319.84 |
-126.35 |
49.33 |
6.43e-06 |
| Age^2 |
-37.53 |
-127.18 |
52.12 |
45.72 |
0.41 |
| Mixed or multiple ethnic origins |
1.70 |
-1.44 |
4.84 |
1.60 |
0.29 |
| Asian or Asian British |
8.95 |
2.90 |
14.99 |
3.08 |
0.004 |
| African or African British |
5.00 |
-4.52 |
14.51 |
4.85 |
0.30 |
| Other ethnicity |
4.69 |
0.18 |
9.20 |
2.30 |
0.04 |
| Time difference: Lockdown to baseline |
0.31 |
0.05 |
0.58 |
0.13 |
0.02 |
| 2442 |
0.07 |
0.06 |
29.25 |
5.42e-34 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
8.02 |
5.45 |
10.60 |
1.31 |
1.18e-09 |
| Depressive and anxiety disorder |
4.48 |
2.85 |
6.11 |
0.83 |
8.44e-08 |
| Only depressive disorder |
2.32 |
0.14 |
4.49 |
1.11 |
0.04 |
| Only anxiety disorder |
0.91 |
-1.42 |
3.24 |
1.19 |
0.45 |
| Eating disorders |
1.43 |
-0.01 |
2.86 |
0.73 |
0.05 |
| OCDs |
6.91 |
5.65 |
8.18 |
0.65 |
3.75e-26 |
| Psychotic and bipolar disorder |
6.18 |
2.53 |
9.84 |
1.86 |
9.26e-04 |
| Only psychotic disorder |
3.00 |
0.05 |
5.95 |
1.50 |
0.05 |
| Only bipolar disorder |
3.50 |
1.40 |
5.60 |
1.07 |
0.001 |
| PTSD |
2.22 |
0.96 |
3.48 |
0.64 |
5.45e-04 |
| ASD |
6.09 |
3.39 |
8.79 |
1.38 |
9.99e-06 |
| ADHD |
0.08 |
-3.75 |
3.91 |
1.95 |
0.97 |
| Personality disorder |
2.78 |
1.12 |
4.43 |
0.85 |
0.001 |
| Female |
-0.74 |
-2.05 |
0.56 |
0.66 |
0.26 |
| Non-binary/Self-defined |
1.37 |
-2.09 |
4.82 |
1.76 |
0.44 |
| Age |
-169.39 |
-266.76 |
-72.01 |
49.66 |
6.58e-04 |
| Age^2 |
-38.86 |
-128.13 |
50.41 |
45.52 |
0.39 |
| Mixed or multiple ethnic origins |
1.12 |
-1.96 |
4.19 |
1.57 |
0.48 |
| Asian or Asian British |
8.94 |
2.96 |
14.92 |
3.05 |
0.003 |
| African or African British |
-0.06 |
-9.99 |
9.88 |
5.06 |
0.99 |
| Other ethnicity |
2.81 |
-1.66 |
7.28 |
2.28 |
0.22 |
| Key worker |
-1.40 |
-2.40 |
-0.40 |
0.51 |
0.006 |
| Time difference: Lockdown to baseline |
0.26 |
0.01 |
0.52 |
0.13 |
0.04 |
| 2442 |
0.07 |
0.06 |
29.25 |
5.42e-34 |
6 |
OCIR prepan
Regression: Change scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
2.00 |
-10.13 |
14.13 |
6.17 |
0.75 |
| Anxiety disorders |
-10.07 |
-23.35 |
3.22 |
6.76 |
0.14 |
| Eating disorders |
-8.00 |
-27.17 |
11.17 |
9.76 |
0.41 |
| OCDs |
-12.64 |
-26.32 |
1.04 |
6.96 |
0.07 |
| PTSD |
-24.50 |
-43.67 |
-5.33 |
9.76 |
0.01 |
| Depressive disorders |
-10.13 |
-22.30 |
2.05 |
6.19 |
0.10 |
| Bipolar disorders |
-9.66 |
-22.17 |
2.85 |
6.36 |
0.13 |
| 461 |
0.02 |
0.00 |
1.18 |
0.31 |
6 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
-1.97 |
-9.82 |
5.88 |
3.99 |
0.62 |
| Depressive and anxiety disorder |
-4.69 |
-12.65 |
3.26 |
4.05 |
0.25 |
| Only depressive disorder |
-4.49 |
-13.22 |
4.24 |
4.44 |
0.31 |
| Only anxiety disorder |
-8.20 |
-16.94 |
0.54 |
4.45 |
0.07 |
| Eating disorders |
-0.11 |
-2.79 |
2.58 |
1.37 |
0.94 |
| OCDs |
-1.25 |
-3.47 |
0.98 |
1.13 |
0.27 |
| Psychotic and bipolar disorder |
12.95 |
5.33 |
20.57 |
3.88 |
9.07e-04 |
| Only psychotic disorder |
-0.95 |
-6.48 |
4.59 |
2.82 |
0.74 |
| Only bipolar disorder |
-1.15 |
-4.80 |
2.50 |
1.86 |
0.54 |
| PTSD |
-3.79 |
-6.25 |
-1.33 |
1.25 |
0.003 |
| ASD |
-0.45 |
-4.77 |
3.88 |
2.20 |
0.84 |
| ADHD |
6.08 |
-0.41 |
12.57 |
3.30 |
0.07 |
| Personality disorder |
-1.65 |
-4.91 |
1.61 |
1.66 |
0.32 |
| 461 |
0.02 |
0.00 |
1.18 |
0.31 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
1.73 |
-12.15 |
15.61 |
7.06 |
0.81 |
| Anxiety disorders |
-9.13 |
-22.53 |
4.28 |
6.82 |
0.18 |
| Eating disorders |
-6.64 |
-25.80 |
12.52 |
9.75 |
0.50 |
| OCDs |
-11.81 |
-25.60 |
1.98 |
7.02 |
0.09 |
| PTSD |
-22.97 |
-42.22 |
-3.71 |
9.80 |
0.02 |
| Depressive disorders |
-10.12 |
-22.45 |
2.20 |
6.27 |
0.11 |
| Bipolar disorders |
-10.10 |
-22.75 |
2.54 |
6.43 |
0.12 |
| Female |
-2.04 |
-4.91 |
0.82 |
1.46 |
0.16 |
| Non-binary/Self-defined |
-2.54 |
-8.26 |
3.19 |
2.91 |
0.38 |
| age_category_collapsed_reordered16-18 |
-7.40 |
-14.32 |
-0.48 |
3.52 |
0.04 |
| 19-25 years |
-3.91 |
-6.81 |
-1.01 |
1.48 |
0.008 |
| 36-45 years |
-0.20 |
-3.22 |
2.82 |
1.54 |
0.90 |
| 46-55 years |
-0.20 |
-3.10 |
2.70 |
1.47 |
0.89 |
| 56-65 years |
-1.80 |
-5.35 |
1.75 |
1.81 |
0.32 |
| 66-70 years |
-0.80 |
-7.09 |
5.49 |
3.20 |
0.80 |
| 71-75 years |
0.67 |
-11.43 |
12.78 |
6.16 |
0.91 |
| Mixed or multiple ethnic origins |
1.93 |
-4.21 |
8.07 |
3.12 |
0.54 |
| Asian or Asian British |
-25.05 |
-39.75 |
-10.34 |
7.48 |
8.84e-04 |
| Other ethnicity |
1.40 |
-6.63 |
9.43 |
4.09 |
0.73 |
| Time difference: Lockdown to baseline |
0.48 |
-0.27 |
1.22 |
0.38 |
0.21 |
| 461 |
0.02 |
0.00 |
1.18 |
0.31 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-3.71 |
-14.48 |
7.07 |
5.48 |
0.50 |
| Depressive and anxiety disorder |
-4.21 |
-13.00 |
4.57 |
4.47 |
0.35 |
| Only depressive disorder |
-4.39 |
-13.86 |
5.09 |
4.82 |
0.36 |
| Only anxiety disorder |
-6.76 |
-16.26 |
2.74 |
4.83 |
0.16 |
| Eating disorders |
0.17 |
-2.56 |
2.90 |
1.39 |
0.90 |
| OCDs |
-1.18 |
-3.43 |
1.07 |
1.14 |
0.30 |
| Psychotic and bipolar disorder |
11.07 |
3.34 |
18.80 |
3.93 |
0.005 |
| Only psychotic disorder |
-1.49 |
-7.14 |
4.17 |
2.88 |
0.61 |
| Only bipolar disorder |
-1.14 |
-4.87 |
2.58 |
1.89 |
0.55 |
| PTSD |
-3.44 |
-5.98 |
-0.91 |
1.29 |
0.008 |
| ASD |
-0.41 |
-4.79 |
3.96 |
2.22 |
0.85 |
| ADHD |
5.05 |
-1.48 |
11.59 |
3.32 |
0.13 |
| Personality disorder |
-1.01 |
-4.29 |
2.28 |
1.67 |
0.55 |
| Female |
-1.99 |
-5.10 |
1.12 |
1.58 |
0.21 |
| Non-binary/Self-defined |
-1.89 |
-7.96 |
4.18 |
3.09 |
0.54 |
| age_category_collapsed_reordered16-18 |
-6.38 |
-13.25 |
0.49 |
3.49 |
0.07 |
| 19-25 years |
-3.47 |
-6.45 |
-0.50 |
1.51 |
0.02 |
| 36-45 years |
-0.49 |
-3.58 |
2.60 |
1.57 |
0.75 |
| 46-55 years |
-0.07 |
-3.09 |
2.96 |
1.54 |
0.97 |
| 56-65 years |
-2.03 |
-5.77 |
1.72 |
1.91 |
0.29 |
| 66-70 years |
-0.94 |
-7.31 |
5.43 |
3.24 |
0.77 |
| 71-75 years |
2.45 |
-8.30 |
13.20 |
5.47 |
0.65 |
| Mixed or multiple ethnic origins |
2.72 |
-3.98 |
9.43 |
3.41 |
0.42 |
| Asian or Asian British |
-22.95 |
-37.79 |
-8.11 |
7.55 |
0.003 |
| Other ethnicity |
1.09 |
-6.91 |
9.09 |
4.07 |
0.79 |
| Key worker |
1.19 |
-1.02 |
3.40 |
1.12 |
0.29 |
| Time difference: Lockdown to baseline |
0.52 |
-0.24 |
1.27 |
0.38 |
0.18 |
| 461 |
0.02 |
0.00 |
1.18 |
0.31 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
0.84 |
-12.78 |
14.45 |
6.93 |
0.90 |
| Anxiety disorders |
-10.00 |
-23.22 |
3.22 |
6.73 |
0.14 |
| Eating disorders |
-6.07 |
-25.01 |
12.87 |
9.64 |
0.53 |
| OCDs |
-11.91 |
-25.40 |
1.58 |
6.86 |
0.08 |
| PTSD |
-24.07 |
-43.05 |
-5.09 |
9.66 |
0.01 |
| Depressive disorders |
-10.26 |
-22.36 |
1.84 |
6.16 |
0.10 |
| Bipolar disorders |
-10.55 |
-22.99 |
1.89 |
6.33 |
0.10 |
| Female |
-1.93 |
-4.78 |
0.92 |
1.45 |
0.18 |
| Non-binary/Self-defined |
-2.35 |
-8.04 |
3.34 |
2.90 |
0.42 |
| Age |
44.09 |
-77.37 |
165.55 |
61.80 |
0.48 |
| Age^2 |
-166.87 |
-292.03 |
-41.71 |
63.68 |
0.009 |
| Mixed or multiple ethnic origins |
1.67 |
-4.43 |
7.78 |
3.11 |
0.59 |
| Asian or Asian British |
-25.30 |
-39.96 |
-10.64 |
7.46 |
7.58e-04 |
| Other ethnicity |
1.91 |
-6.05 |
9.88 |
4.05 |
0.64 |
| Time difference: Lockdown to baseline |
0.46 |
-0.27 |
1.20 |
0.37 |
0.22 |
| 461 |
0.02 |
0.00 |
1.18 |
0.31 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-3.72 |
-14.08 |
6.64 |
5.27 |
0.48 |
| Depressive and anxiety disorder |
-4.92 |
-13.51 |
3.68 |
4.37 |
0.26 |
| Only depressive disorder |
-5.54 |
-14.81 |
3.74 |
4.72 |
0.24 |
| Only anxiety disorder |
-7.95 |
-17.28 |
1.38 |
4.74 |
0.09 |
| Eating disorders |
0.13 |
-2.59 |
2.85 |
1.38 |
0.92 |
| OCDs |
-1.26 |
-3.50 |
0.97 |
1.13 |
0.27 |
| Psychotic and bipolar disorder |
10.67 |
2.96 |
18.37 |
3.92 |
0.007 |
| Only psychotic disorder |
-1.46 |
-7.04 |
4.12 |
2.84 |
0.61 |
| Only bipolar disorder |
-1.38 |
-5.08 |
2.31 |
1.88 |
0.46 |
| PTSD |
-3.64 |
-6.16 |
-1.12 |
1.28 |
0.005 |
| ASD |
-0.23 |
-4.58 |
4.13 |
2.22 |
0.92 |
| ADHD |
5.38 |
-1.11 |
11.86 |
3.30 |
0.10 |
| Personality disorder |
-1.16 |
-4.42 |
2.11 |
1.66 |
0.49 |
| Female |
-2.04 |
-5.14 |
1.05 |
1.57 |
0.19 |
| Non-binary/Self-defined |
-1.90 |
-7.92 |
4.12 |
3.06 |
0.54 |
| Age |
43.48 |
-82.96 |
169.93 |
64.32 |
0.50 |
| Age^2 |
-132.59 |
-260.35 |
-4.83 |
64.99 |
0.04 |
| Mixed or multiple ethnic origins |
2.71 |
-3.96 |
9.39 |
3.40 |
0.42 |
| Asian or Asian British |
-23.00 |
-37.79 |
-8.22 |
7.52 |
0.002 |
| Other ethnicity |
1.39 |
-6.54 |
9.32 |
4.04 |
0.73 |
| Key worker |
1.23 |
-0.98 |
3.43 |
1.12 |
0.27 |
| Time difference: Lockdown to baseline |
0.50 |
-0.24 |
1.25 |
0.38 |
0.19 |
| 461 |
0.02 |
0.00 |
1.18 |
0.31 |
6 |
Regression: Absolute scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
9.46 |
-1.49 |
20.41 |
5.57 |
0.09 |
| ocir.sum_score_prepan |
0.66 |
0.59 |
0.72 |
0.03 |
3.75e-65 |
| Anxiety disorders |
-11.47 |
-23.37 |
0.44 |
6.06 |
0.06 |
| Eating disorders |
-9.26 |
-26.44 |
7.92 |
8.74 |
0.29 |
| OCDs |
-9.17 |
-21.44 |
3.10 |
6.24 |
0.14 |
| PTSD |
-20.94 |
-38.13 |
-3.75 |
8.75 |
0.02 |
| Depressive disorders |
-8.48 |
-19.39 |
2.43 |
5.55 |
0.13 |
| Bipolar disorders |
-6.31 |
-17.53 |
4.92 |
5.71 |
0.27 |
| 461 |
0.49 |
0.48 |
62.80 |
7.79e-63 |
7 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
5.70 |
-1.50 |
12.89 |
3.66 |
0.12 |
| ocir.sum_score_prepan |
0.64 |
0.57 |
0.71 |
0.04 |
1.22e-53 |
| Depressive and anxiety disorder |
-4.17 |
-11.31 |
2.97 |
3.63 |
0.25 |
| Only depressive disorder |
-5.37 |
-13.21 |
2.46 |
3.99 |
0.18 |
| Only anxiety disorder |
-8.62 |
-16.46 |
-0.78 |
3.99 |
0.03 |
| Eating disorders |
0.48 |
-1.94 |
2.89 |
1.23 |
0.70 |
| OCDs |
2.28 |
0.17 |
4.39 |
1.07 |
0.03 |
| Psychotic and bipolar disorder |
11.83 |
4.99 |
18.67 |
3.48 |
7.37e-04 |
| Only psychotic disorder |
0.58 |
-4.40 |
5.55 |
2.53 |
0.82 |
| Only bipolar disorder |
0.87 |
-2.43 |
4.17 |
1.68 |
0.61 |
| PTSD |
-2.65 |
-4.87 |
-0.43 |
1.13 |
0.02 |
| ASD |
0.22 |
-3.66 |
4.10 |
1.97 |
0.91 |
| ADHD |
4.02 |
-1.82 |
9.85 |
2.97 |
0.18 |
| Personality disorder |
-0.69 |
-3.62 |
2.25 |
1.49 |
0.65 |
| 1873 |
0.03 |
0.03 |
9.40 |
3.43e-10 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
13.35 |
-2.05 |
28.75 |
7.83 |
0.09 |
| ocir.sum_score_prepan |
0.67 |
0.61 |
0.74 |
0.03 |
3.92e-63 |
| Anxiety disorders |
-15.91 |
-30.60 |
-1.22 |
7.47 |
0.03 |
| Eating disorders |
-13.43 |
-32.72 |
5.85 |
9.81 |
0.17 |
| OCDs |
-14.01 |
-28.97 |
0.95 |
7.61 |
0.07 |
| PTSD |
-25.33 |
-44.69 |
-5.98 |
9.85 |
0.01 |
| Depressive disorders |
-13.55 |
-27.42 |
0.32 |
7.06 |
0.06 |
| Bipolar disorders |
-11.59 |
-25.69 |
2.52 |
7.18 |
0.11 |
| Female |
-1.34 |
-3.96 |
1.27 |
1.33 |
0.31 |
| Non-binary/Self-defined |
-1.34 |
-6.56 |
3.88 |
2.66 |
0.61 |
| age_category_collapsed_reordered16-18 |
-6.36 |
-12.72 |
0.00 |
3.24 |
0.05 |
| 19-25 years |
-1.93 |
-4.61 |
0.75 |
1.36 |
0.16 |
| 36-45 years |
0.05 |
-2.70 |
2.80 |
1.40 |
0.97 |
| 46-55 years |
0.33 |
-2.32 |
2.98 |
1.35 |
0.81 |
| 56-65 years |
-1.28 |
-4.54 |
1.97 |
1.66 |
0.44 |
| 66-70 years |
-1.43 |
-7.21 |
4.36 |
2.94 |
0.63 |
| 71-75 years |
-3.50 |
-14.59 |
7.59 |
5.64 |
0.54 |
| Mixed or multiple ethnic origins |
0.20 |
-5.40 |
5.79 |
2.85 |
0.94 |
| Asian or Asian British |
-16.52 |
-30.07 |
-2.98 |
6.89 |
0.02 |
| Other ethnicity |
4.05 |
-3.28 |
11.39 |
3.73 |
0.28 |
| Key worker |
0.24 |
-1.69 |
2.17 |
0.98 |
0.80 |
| Time difference: Lockdown to baseline |
0.35 |
-0.33 |
1.03 |
0.35 |
0.31 |
| 1873 |
0.03 |
0.03 |
9.40 |
3.43e-10 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
4.89 |
-5.04 |
14.82 |
5.05 |
0.33 |
| ocir.sum_score_prepan |
0.65 |
0.57 |
0.72 |
0.04 |
6.31e-51 |
| Depressive and anxiety disorder |
-5.03 |
-12.99 |
2.93 |
4.05 |
0.22 |
| Only depressive disorder |
-6.08 |
-14.67 |
2.51 |
4.37 |
0.17 |
| Only anxiety disorder |
-8.82 |
-17.44 |
-0.20 |
4.38 |
0.04 |
| Eating disorders |
0.93 |
-1.55 |
3.41 |
1.26 |
0.46 |
| OCDs |
2.33 |
0.17 |
4.50 |
1.10 |
0.03 |
| Psychotic and bipolar disorder |
10.56 |
3.55 |
17.56 |
3.56 |
0.003 |
| Only psychotic disorder |
0.15 |
-4.98 |
5.29 |
2.61 |
0.95 |
| Only bipolar disorder |
0.65 |
-2.75 |
4.04 |
1.73 |
0.71 |
| PTSD |
-2.35 |
-4.66 |
-0.04 |
1.17 |
0.05 |
| ASD |
-0.13 |
-4.09 |
3.84 |
2.02 |
0.95 |
| ADHD |
3.38 |
-2.55 |
9.31 |
3.02 |
0.26 |
| Personality disorder |
-0.16 |
-3.14 |
2.81 |
1.52 |
0.91 |
| Female |
-1.95 |
-4.77 |
0.86 |
1.43 |
0.17 |
| Non-binary/Self-defined |
-1.31 |
-6.81 |
4.19 |
2.80 |
0.64 |
| age_category_collapsed_reordered16-18 |
-5.33 |
-11.56 |
0.90 |
3.17 |
0.09 |
| 19-25 years |
-1.37 |
-4.11 |
1.36 |
1.39 |
0.32 |
| 36-45 years |
-0.10 |
-2.90 |
2.70 |
1.42 |
0.94 |
| 46-55 years |
1.36 |
-1.40 |
4.12 |
1.40 |
0.33 |
| 56-65 years |
-1.93 |
-5.32 |
1.47 |
1.73 |
0.27 |
| 66-70 years |
-1.19 |
-6.96 |
4.58 |
2.94 |
0.69 |
| 71-75 years |
-0.08 |
-9.84 |
9.68 |
4.96 |
0.99 |
| Mixed or multiple ethnic origins |
0.09 |
-6.01 |
6.19 |
3.10 |
0.98 |
| Asian or Asian British |
-12.68 |
-26.30 |
0.94 |
6.93 |
0.07 |
| Other ethnicity |
3.67 |
-3.60 |
10.94 |
3.70 |
0.32 |
| Key worker |
0.09 |
-1.92 |
2.11 |
1.02 |
0.93 |
| Time difference: Lockdown to baseline |
0.47 |
-0.22 |
1.15 |
0.35 |
0.18 |
| 1873 |
0.03 |
0.03 |
9.40 |
3.43e-10 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
11.54 |
-3.40 |
26.48 |
7.60 |
0.13 |
| ocir.sum_score_prepan |
0.67 |
0.61 |
0.74 |
0.03 |
1.32e-64 |
| Anxiety disorders |
-15.13 |
-29.48 |
-0.77 |
7.30 |
0.04 |
| Eating disorders |
-11.52 |
-30.43 |
7.38 |
9.62 |
0.23 |
| OCDs |
-12.50 |
-27.01 |
2.01 |
7.38 |
0.09 |
| PTSD |
-24.50 |
-43.44 |
-5.56 |
9.64 |
0.01 |
| Depressive disorders |
-12.25 |
-25.74 |
1.23 |
6.86 |
0.07 |
| Bipolar disorders |
-10.43 |
-24.17 |
3.32 |
6.99 |
0.14 |
| Female |
-1.26 |
-3.86 |
1.34 |
1.32 |
0.34 |
| Non-binary/Self-defined |
-1.17 |
-6.34 |
4.01 |
2.63 |
0.66 |
| Age |
4.97 |
-107.16 |
117.10 |
57.05 |
0.93 |
| Age^2 |
-138.61 |
-253.83 |
-23.39 |
58.63 |
0.02 |
| Mixed or multiple ethnic origins |
0.14 |
-5.40 |
5.69 |
2.82 |
0.96 |
| Asian or Asian British |
-16.84 |
-30.31 |
-3.37 |
6.85 |
0.01 |
| Other ethnicity |
4.19 |
-3.06 |
11.44 |
3.69 |
0.26 |
| Key worker |
0.15 |
-1.77 |
2.08 |
0.98 |
0.88 |
| Time difference: Lockdown to baseline |
0.34 |
-0.33 |
1.01 |
0.34 |
0.32 |
| 1873 |
0.03 |
0.03 |
9.40 |
3.43e-10 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
4.99 |
-4.56 |
14.54 |
4.86 |
0.30 |
| ocir.sum_score_prepan |
0.65 |
0.58 |
0.72 |
0.04 |
5.45e-53 |
| Depressive and anxiety disorder |
-5.00 |
-12.78 |
2.78 |
3.96 |
0.21 |
| Only depressive disorder |
-6.50 |
-14.90 |
1.90 |
4.27 |
0.13 |
| Only anxiety disorder |
-9.10 |
-17.55 |
-0.65 |
4.30 |
0.03 |
| Eating disorders |
0.80 |
-1.67 |
3.26 |
1.25 |
0.53 |
| OCDs |
2.13 |
-0.01 |
4.27 |
1.09 |
0.05 |
| Psychotic and bipolar disorder |
10.35 |
3.37 |
17.33 |
3.55 |
0.004 |
| Only psychotic disorder |
-0.07 |
-5.14 |
4.99 |
2.58 |
0.98 |
| Only bipolar disorder |
0.64 |
-2.73 |
4.02 |
1.72 |
0.71 |
| PTSD |
-2.55 |
-4.84 |
-0.25 |
1.17 |
0.03 |
| ASD |
0.15 |
-3.79 |
4.10 |
2.01 |
0.94 |
| ADHD |
3.39 |
-2.50 |
9.27 |
2.99 |
0.26 |
| Personality disorder |
-0.37 |
-3.33 |
2.60 |
1.51 |
0.81 |
| Female |
-1.94 |
-4.74 |
0.86 |
1.42 |
0.17 |
| Non-binary/Self-defined |
-1.21 |
-6.66 |
4.24 |
2.77 |
0.66 |
| Age |
12.53 |
-102.14 |
127.20 |
58.33 |
0.83 |
| Age^2 |
-116.94 |
-232.66 |
-1.21 |
58.87 |
0.05 |
| Mixed or multiple ethnic origins |
0.29 |
-5.77 |
6.35 |
3.09 |
0.93 |
| Asian or Asian British |
-13.24 |
-26.78 |
0.30 |
6.89 |
0.06 |
| Other ethnicity |
3.58 |
-3.62 |
10.78 |
3.66 |
0.33 |
| Key worker |
0.06 |
-1.95 |
2.07 |
1.02 |
0.95 |
| Time difference: Lockdown to baseline |
0.42 |
-0.26 |
1.10 |
0.34 |
0.22 |
| 1873 |
0.03 |
0.03 |
9.40 |
3.43e-10 |
6 |
OCIR retro
Regression: Change scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
3.87 |
3.16 |
4.58 |
0.36 |
3.40e-26 |
| Anxiety disorders |
-0.58 |
-1.82 |
0.67 |
0.64 |
0.36 |
| Eating disorders |
-3.63 |
-7.20 |
-0.06 |
1.82 |
0.05 |
| OCDs |
-1.87 |
-4.16 |
0.42 |
1.17 |
0.11 |
| PTSD |
1.25 |
-1.19 |
3.70 |
1.25 |
0.31 |
| Depressive disorders |
-3.76 |
-4.55 |
-2.97 |
0.40 |
1.37e-20 |
| Bipolar disorders |
-3.66 |
-4.97 |
-2.35 |
0.67 |
4.34e-08 |
| 4580 |
0.03 |
0.02 |
20.52 |
7.79e-24 |
6 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
3.83 |
3.19 |
4.47 |
0.33 |
4.95e-31 |
| Depressive and anxiety disorder |
-4.38 |
-5.16 |
-3.60 |
0.40 |
6.75e-28 |
| Only depressive disorder |
-2.10 |
-3.19 |
-1.02 |
0.55 |
1.50e-04 |
| Only anxiety disorder |
-1.43 |
-2.54 |
-0.31 |
0.57 |
0.01 |
| Eating disorders |
-0.26 |
-1.19 |
0.67 |
0.48 |
0.59 |
| OCDs |
0.32 |
-0.49 |
1.13 |
0.41 |
0.43 |
| Psychotic and bipolar disorder |
2.21 |
0.02 |
4.40 |
1.12 |
0.05 |
| Only psychotic disorder |
0.57 |
-1.39 |
2.53 |
1.00 |
0.57 |
| Only bipolar disorder |
-0.56 |
-1.93 |
0.82 |
0.70 |
0.43 |
| PTSD |
0.21 |
-0.58 |
1.00 |
0.40 |
0.60 |
| ASD |
1.83 |
0.35 |
3.32 |
0.76 |
0.02 |
| ADHD |
2.29 |
0.19 |
4.39 |
1.07 |
0.03 |
| Personality disorder |
-0.61 |
-1.70 |
0.47 |
0.55 |
0.27 |
| 4580 |
0.03 |
0.02 |
20.52 |
7.79e-24 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
11.16 |
9.83 |
12.49 |
0.68 |
6.08e-59 |
| Anxiety disorders |
-0.15 |
-1.34 |
1.03 |
0.60 |
0.80 |
| Eating disorders |
-2.14 |
-5.45 |
1.17 |
1.69 |
0.21 |
| OCDs |
-0.31 |
-2.46 |
1.84 |
1.10 |
0.78 |
| PTSD |
1.06 |
-1.24 |
3.36 |
1.17 |
0.37 |
| Depressive disorders |
-2.01 |
-2.78 |
-1.24 |
0.39 |
3.43e-07 |
| Bipolar disorders |
-1.75 |
-2.99 |
-0.50 |
0.63 |
0.006 |
| Female |
0.45 |
-0.29 |
1.19 |
0.38 |
0.24 |
| Non-binary/Self-defined |
0.14 |
-1.87 |
2.15 |
1.02 |
0.89 |
| age_category_collapsed_reordered16-18 |
4.16 |
2.78 |
5.54 |
0.70 |
3.81e-09 |
| 19-25 years |
-0.46 |
-1.47 |
0.54 |
0.51 |
0.36 |
| 36-45 years |
0.29 |
-0.63 |
1.20 |
0.46 |
0.54 |
| 46-55 years |
0.31 |
-0.53 |
1.15 |
0.43 |
0.47 |
| 56-65 years |
2.12 |
1.27 |
2.96 |
0.43 |
9.76e-07 |
| 66-70 years |
2.04 |
0.77 |
3.32 |
0.65 |
0.002 |
| 71-75 years |
2.83 |
1.26 |
4.40 |
0.80 |
4.03e-04 |
| 76+ years |
0.53 |
-2.66 |
3.73 |
1.63 |
0.74 |
| Mixed or multiple ethnic origins |
1.18 |
-0.57 |
2.92 |
0.89 |
0.19 |
| Asian or Asian British |
2.45 |
-0.20 |
5.10 |
1.35 |
0.07 |
| African or African British |
0.16 |
-4.88 |
5.20 |
2.57 |
0.95 |
| Other ethnicity |
-0.25 |
-2.64 |
2.13 |
1.22 |
0.84 |
| Time difference: Lockdown to baseline |
-1.66 |
-1.78 |
-1.54 |
0.06 |
5.47e-142 |
| 4580 |
0.03 |
0.02 |
20.52 |
7.79e-24 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
11.20 |
9.85 |
12.54 |
0.69 |
5.09e-58 |
| Depressive and anxiety disorder |
-2.52 |
-3.29 |
-1.76 |
0.39 |
1.03e-10 |
| Only depressive disorder |
-1.45 |
-2.49 |
-0.41 |
0.53 |
0.006 |
| Only anxiety disorder |
-0.73 |
-1.79 |
0.33 |
0.54 |
0.18 |
| Eating disorders |
-0.09 |
-0.96 |
0.78 |
0.44 |
0.83 |
| OCDs |
0.39 |
-0.37 |
1.15 |
0.39 |
0.31 |
| Psychotic and bipolar disorder |
2.26 |
0.22 |
4.29 |
1.04 |
0.03 |
| Only psychotic disorder |
0.29 |
-1.53 |
2.11 |
0.93 |
0.75 |
| Only bipolar disorder |
-0.32 |
-1.62 |
0.97 |
0.66 |
0.62 |
| PTSD |
0.16 |
-0.59 |
0.91 |
0.38 |
0.68 |
| ASD |
0.99 |
-0.43 |
2.40 |
0.72 |
0.17 |
| ADHD |
1.72 |
-0.23 |
3.66 |
0.99 |
0.08 |
| Personality disorder |
-0.24 |
-1.25 |
0.77 |
0.52 |
0.64 |
| Female |
0.30 |
-0.46 |
1.06 |
0.39 |
0.43 |
| Non-binary/Self-defined |
-0.66 |
-2.72 |
1.40 |
1.05 |
0.53 |
| age_category_collapsed_reordered16-18 |
4.02 |
2.65 |
5.40 |
0.70 |
1.03e-08 |
| 19-25 years |
-0.47 |
-1.49 |
0.55 |
0.52 |
0.36 |
| 36-45 years |
0.24 |
-0.69 |
1.17 |
0.48 |
0.61 |
| 46-55 years |
0.28 |
-0.59 |
1.14 |
0.44 |
0.53 |
| 56-65 years |
1.85 |
0.97 |
2.73 |
0.45 |
3.94e-05 |
| 66-70 years |
2.18 |
0.85 |
3.52 |
0.68 |
0.001 |
| 71-75 years |
2.14 |
0.52 |
3.76 |
0.83 |
0.010 |
| 76+ years |
0.02 |
-3.33 |
3.37 |
1.71 |
0.99 |
| Mixed or multiple ethnic origins |
1.39 |
-0.41 |
3.19 |
0.92 |
0.13 |
| Asian or Asian British |
2.32 |
-0.29 |
4.92 |
1.33 |
0.08 |
| African or African British |
-0.61 |
-5.84 |
4.61 |
2.66 |
0.82 |
| Other ethnicity |
-0.16 |
-2.65 |
2.32 |
1.27 |
0.90 |
| Key worker |
-0.09 |
-0.67 |
0.48 |
0.29 |
0.75 |
| Time difference: Lockdown to baseline |
-1.61 |
-1.73 |
-1.48 |
0.06 |
1.65e-131 |
| 4580 |
0.03 |
0.02 |
20.52 |
7.79e-24 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-3.81 |
-5.41 |
-2.22 |
0.81 |
3.00e-06 |
| Anxiety disorders |
-0.48 |
-2.13 |
1.16 |
0.84 |
0.56 |
| Eating disorders |
1.22 |
-2.21 |
4.65 |
1.75 |
0.49 |
| OCDs |
-1.12 |
-3.76 |
1.52 |
1.35 |
0.40 |
| PTSD |
-2.84 |
-6.28 |
0.60 |
1.76 |
0.11 |
| Depressive disorders |
-0.89 |
-1.95 |
0.16 |
0.54 |
0.10 |
| Bipolar disorders |
-1.24 |
-2.69 |
0.20 |
0.74 |
0.09 |
| Female |
-0.39 |
-1.17 |
0.39 |
0.40 |
0.32 |
| Non-binary/Self-defined |
-0.35 |
-2.39 |
1.68 |
1.04 |
0.73 |
| Age |
93.66 |
38.04 |
149.28 |
28.36 |
9.74e-04 |
| Age^2 |
-24.39 |
-75.68 |
26.90 |
26.15 |
0.35 |
| Mixed or multiple ethnic origins |
2.58 |
0.75 |
4.42 |
0.94 |
0.006 |
| Asian or Asian British |
0.03 |
-3.47 |
3.54 |
1.79 |
0.98 |
| African or African British |
1.60 |
-3.92 |
7.12 |
2.81 |
0.57 |
| Other ethnicity |
1.06 |
-1.56 |
3.68 |
1.33 |
0.43 |
| Time difference: Lockdown to baseline |
-0.01 |
-0.17 |
0.14 |
0.08 |
0.87 |
| 2385 |
0.00 |
0.00 |
1.87 |
0.08 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-3.52 |
-5.11 |
-1.93 |
0.81 |
1.42e-05 |
| Depressive and anxiety disorder |
-0.70 |
-1.70 |
0.31 |
0.51 |
0.17 |
| Only depressive disorder |
-1.16 |
-2.50 |
0.18 |
0.68 |
0.09 |
| Only anxiety disorder |
-1.07 |
-2.50 |
0.35 |
0.73 |
0.14 |
| Eating disorders |
0.46 |
-0.42 |
1.34 |
0.45 |
0.31 |
| OCDs |
-0.24 |
-1.01 |
0.54 |
0.39 |
0.55 |
| Psychotic and bipolar disorder |
0.50 |
-1.75 |
2.75 |
1.15 |
0.66 |
| Only psychotic disorder |
0.13 |
-1.69 |
1.94 |
0.92 |
0.89 |
| Only bipolar disorder |
-0.24 |
-1.51 |
1.04 |
0.65 |
0.72 |
| PTSD |
-0.56 |
-1.33 |
0.21 |
0.39 |
0.16 |
| ASD |
0.01 |
-1.65 |
1.67 |
0.85 |
0.99 |
| ADHD |
2.03 |
-0.36 |
4.42 |
1.22 |
0.10 |
| Personality disorder |
-0.87 |
-1.89 |
0.14 |
0.52 |
0.09 |
| Female |
-0.57 |
-1.37 |
0.23 |
0.41 |
0.16 |
| Non-binary/Self-defined |
-0.93 |
-3.04 |
1.17 |
1.07 |
0.39 |
| Age |
83.90 |
25.33 |
142.47 |
29.87 |
0.005 |
| Age^2 |
-29.91 |
-83.48 |
23.66 |
27.32 |
0.27 |
| Mixed or multiple ethnic origins |
2.75 |
0.87 |
4.64 |
0.96 |
0.004 |
| Asian or Asian British |
-1.48 |
-5.12 |
2.16 |
1.86 |
0.42 |
| African or African British |
-0.61 |
-6.65 |
5.43 |
3.08 |
0.84 |
| Other ethnicity |
1.43 |
-1.29 |
4.15 |
1.39 |
0.30 |
| Key worker |
0.10 |
-0.51 |
0.72 |
0.31 |
0.74 |
| Time difference: Lockdown to baseline |
-0.03 |
-0.19 |
0.12 |
0.08 |
0.68 |
| 2385 |
0.00 |
0.00 |
1.87 |
0.08 |
6 |
Regression: Absolute scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
6.42 |
5.72 |
7.12 |
0.36 |
5.01e-70 |
| ocir.sum_score_retro |
0.73 |
0.71 |
0.75 |
0.01 |
0.00e+00 |
| Anxiety disorders |
0.19 |
-0.99 |
1.36 |
0.60 |
0.75 |
| Eating disorders |
-1.55 |
-4.91 |
1.81 |
1.71 |
0.37 |
| OCDs |
1.43 |
-0.74 |
3.60 |
1.11 |
0.20 |
| PTSD |
3.21 |
0.91 |
5.51 |
1.17 |
0.006 |
| Depressive disorders |
-1.36 |
-2.12 |
-0.59 |
0.39 |
5.20e-04 |
| Bipolar disorders |
0.37 |
-0.90 |
1.65 |
0.65 |
0.57 |
| 4580 |
0.52 |
0.51 |
693.97 |
0.00e+00 |
7 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
6.91 |
6.27 |
7.56 |
0.33 |
2.08e-93 |
| ocir.sum_score_retro |
0.70 |
0.68 |
0.73 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
-2.54 |
-3.28 |
-1.80 |
0.38 |
2.15e-11 |
| Only depressive disorder |
-1.69 |
-2.71 |
-0.68 |
0.52 |
0.001 |
| Only anxiety disorder |
-0.70 |
-1.74 |
0.35 |
0.53 |
0.19 |
| Eating disorders |
-0.08 |
-0.95 |
0.79 |
0.44 |
0.85 |
| OCDs |
2.48 |
1.71 |
3.25 |
0.39 |
3.42e-10 |
| Psychotic and bipolar disorder |
3.46 |
1.41 |
5.50 |
1.04 |
9.23e-04 |
| Only psychotic disorder |
1.71 |
-0.12 |
3.54 |
0.93 |
0.07 |
| Only bipolar disorder |
0.58 |
-0.71 |
1.87 |
0.66 |
0.38 |
| PTSD |
0.77 |
0.03 |
1.51 |
0.38 |
0.04 |
| ASD |
3.76 |
2.36 |
5.15 |
0.71 |
1.32e-07 |
| ADHD |
2.12 |
0.17 |
4.08 |
1.00 |
0.03 |
| Personality disorder |
0.66 |
-0.35 |
1.68 |
0.52 |
0.20 |
| 5455 |
0.06 |
0.05 |
53.30 |
3.86e-64 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
12.70 |
11.41 |
14.00 |
0.66 |
6.39e-79 |
| ocir.sum_score_retro |
0.77 |
0.75 |
0.79 |
0.01 |
0.00e+00 |
| Anxiety disorders |
0.27 |
-0.86 |
1.39 |
0.57 |
0.64 |
| Eating disorders |
-0.82 |
-3.97 |
2.33 |
1.61 |
0.61 |
| OCDs |
1.68 |
-0.39 |
3.74 |
1.05 |
0.11 |
| PTSD |
2.70 |
0.49 |
4.91 |
1.13 |
0.02 |
| Depressive disorders |
-0.37 |
-1.12 |
0.38 |
0.38 |
0.33 |
| Bipolar disorders |
1.20 |
-0.02 |
2.42 |
0.62 |
0.05 |
| Female |
0.39 |
-0.31 |
1.10 |
0.36 |
0.28 |
| Non-binary/Self-defined |
0.75 |
-1.16 |
2.66 |
0.97 |
0.44 |
| age_category_collapsed_reordered16-18 |
4.76 |
3.43 |
6.09 |
0.68 |
2.37e-12 |
| 19-25 years |
-0.13 |
-1.09 |
0.83 |
0.49 |
0.78 |
| 36-45 years |
0.00 |
-0.87 |
0.86 |
0.44 |
0.99 |
| 46-55 years |
0.10 |
-0.70 |
0.90 |
0.41 |
0.80 |
| 56-65 years |
1.28 |
0.46 |
2.09 |
0.41 |
0.002 |
| 66-70 years |
0.99 |
-0.25 |
2.22 |
0.63 |
0.12 |
| 71-75 years |
1.06 |
-0.46 |
2.58 |
0.77 |
0.17 |
| 76+ years |
-0.63 |
-3.72 |
2.46 |
1.58 |
0.69 |
| Mixed or multiple ethnic origins |
1.12 |
-0.56 |
2.79 |
0.85 |
0.19 |
| Asian or Asian British |
3.14 |
0.62 |
5.66 |
1.29 |
0.01 |
| African or African British |
0.32 |
-4.47 |
5.11 |
2.45 |
0.90 |
| Other ethnicity |
0.58 |
-1.70 |
2.87 |
1.17 |
0.62 |
| Key worker |
-0.45 |
-0.99 |
0.08 |
0.27 |
0.10 |
| Time difference: Lockdown to baseline |
-1.42 |
-1.54 |
-1.30 |
0.06 |
7.09e-113 |
| 5455 |
0.06 |
0.05 |
53.30 |
3.86e-64 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
12.79 |
11.51 |
14.07 |
0.65 |
1.21e-81 |
| ocir.sum_score_retro |
0.75 |
0.72 |
0.77 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
-1.21 |
-1.94 |
-0.47 |
0.37 |
0.001 |
| Only depressive disorder |
-1.01 |
-1.99 |
-0.03 |
0.50 |
0.04 |
| Only anxiety disorder |
-0.29 |
-1.30 |
0.71 |
0.51 |
0.57 |
| Eating disorders |
-0.04 |
-0.86 |
0.79 |
0.42 |
0.93 |
| OCDs |
2.12 |
1.39 |
2.85 |
0.37 |
1.40e-08 |
| Psychotic and bipolar disorder |
3.32 |
1.38 |
5.25 |
0.98 |
7.68e-04 |
| Only psychotic disorder |
1.21 |
-0.51 |
2.93 |
0.88 |
0.17 |
| Only bipolar disorder |
0.56 |
-0.67 |
1.78 |
0.63 |
0.37 |
| PTSD |
0.70 |
-0.01 |
1.41 |
0.36 |
0.05 |
| ASD |
2.50 |
1.15 |
3.84 |
0.69 |
2.72e-04 |
| ADHD |
1.53 |
-0.31 |
3.38 |
0.94 |
0.10 |
| Personality disorder |
0.74 |
-0.22 |
1.70 |
0.49 |
0.13 |
| Female |
0.17 |
-0.55 |
0.88 |
0.37 |
0.65 |
| Non-binary/Self-defined |
-0.53 |
-2.48 |
1.43 |
1.00 |
0.60 |
| age_category_collapsed_reordered16-18 |
5.03 |
3.72 |
6.33 |
0.67 |
4.96e-14 |
| 19-25 years |
0.04 |
-0.92 |
1.01 |
0.49 |
0.93 |
| 36-45 years |
0.11 |
-0.77 |
1.00 |
0.45 |
0.80 |
| 46-55 years |
0.25 |
-0.57 |
1.08 |
0.42 |
0.54 |
| 56-65 years |
1.31 |
0.47 |
2.14 |
0.43 |
0.002 |
| 66-70 years |
1.55 |
0.29 |
2.81 |
0.64 |
0.02 |
| 71-75 years |
1.18 |
-0.36 |
2.72 |
0.79 |
0.13 |
| 76+ years |
-0.82 |
-3.99 |
2.35 |
1.62 |
0.61 |
| Mixed or multiple ethnic origins |
1.16 |
-0.55 |
2.86 |
0.87 |
0.18 |
| Asian or Asian British |
3.38 |
0.91 |
5.84 |
1.26 |
0.007 |
| African or African British |
-0.84 |
-5.78 |
4.11 |
2.52 |
0.74 |
| Other ethnicity |
0.58 |
-1.77 |
2.93 |
1.20 |
0.63 |
| Key worker |
-0.42 |
-0.96 |
0.13 |
0.28 |
0.13 |
| Time difference: Lockdown to baseline |
-1.35 |
-1.47 |
-1.23 |
0.06 |
1.83e-101 |
| 5455 |
0.06 |
0.05 |
53.30 |
3.86e-64 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-1.67 |
-3.21 |
-0.13 |
0.78 |
0.03 |
| ocir.sum_score_retro |
0.81 |
0.79 |
0.83 |
0.01 |
0.00e+00 |
| Anxiety disorders |
-0.37 |
-1.92 |
1.17 |
0.79 |
0.64 |
| Eating disorders |
2.52 |
-0.70 |
5.73 |
1.64 |
0.12 |
| OCDs |
1.19 |
-1.30 |
3.68 |
1.27 |
0.35 |
| PTSD |
-0.45 |
-3.69 |
2.79 |
1.65 |
0.79 |
| Depressive disorders |
0.62 |
-0.39 |
1.63 |
0.52 |
0.23 |
| Bipolar disorders |
1.45 |
0.06 |
2.85 |
0.71 |
0.04 |
| Female |
-0.33 |
-1.06 |
0.40 |
0.37 |
0.37 |
| Non-binary/Self-defined |
0.23 |
-1.68 |
2.13 |
0.97 |
0.81 |
| Age |
27.04 |
-26.43 |
80.51 |
27.27 |
0.32 |
| Age^2 |
-32.77 |
-81.83 |
16.29 |
25.02 |
0.19 |
| Mixed or multiple ethnic origins |
2.46 |
0.71 |
4.21 |
0.89 |
0.006 |
| Asian or Asian British |
1.73 |
-1.56 |
5.02 |
1.68 |
0.30 |
| African or African British |
2.16 |
-3.01 |
7.33 |
2.64 |
0.41 |
| Other ethnicity |
1.63 |
-0.87 |
4.13 |
1.27 |
0.20 |
| Key worker |
-0.36 |
-0.92 |
0.20 |
0.29 |
0.21 |
| Time difference: Lockdown to baseline |
0.04 |
-0.11 |
0.18 |
0.07 |
0.61 |
| 2391 |
0.07 |
0.07 |
29.22 |
6.27e-34 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-1.09 |
-2.60 |
0.41 |
0.77 |
0.15 |
| ocir.sum_score_retro |
0.79 |
0.77 |
0.82 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
0.40 |
-0.54 |
1.35 |
0.48 |
0.40 |
| Only depressive disorder |
-0.40 |
-1.66 |
0.85 |
0.64 |
0.53 |
| Only anxiety disorder |
-0.64 |
-1.97 |
0.70 |
0.68 |
0.35 |
| Eating disorders |
0.64 |
-0.19 |
1.46 |
0.42 |
0.13 |
| OCDs |
1.24 |
0.50 |
1.98 |
0.38 |
0.001 |
| Psychotic and bipolar disorder |
1.76 |
-0.35 |
3.87 |
1.08 |
0.10 |
| Only psychotic disorder |
0.75 |
-0.94 |
2.44 |
0.86 |
0.39 |
| Only bipolar disorder |
0.51 |
-0.68 |
1.71 |
0.61 |
0.40 |
| PTSD |
-0.01 |
-0.73 |
0.72 |
0.37 |
0.98 |
| ASD |
1.31 |
-0.24 |
2.87 |
0.79 |
0.10 |
| ADHD |
1.72 |
-0.51 |
3.96 |
1.14 |
0.13 |
| Personality disorder |
-0.10 |
-1.06 |
0.85 |
0.49 |
0.83 |
| Female |
-0.59 |
-1.34 |
0.16 |
0.38 |
0.12 |
| Non-binary/Self-defined |
-0.48 |
-2.45 |
1.49 |
1.00 |
0.63 |
| Age |
32.90 |
-22.13 |
87.93 |
28.06 |
0.24 |
| Age^2 |
-32.01 |
-82.08 |
18.07 |
25.53 |
0.21 |
| Mixed or multiple ethnic origins |
2.44 |
0.68 |
4.21 |
0.90 |
0.007 |
| Asian or Asian British |
0.65 |
-2.76 |
4.06 |
1.74 |
0.71 |
| African or African British |
-0.51 |
-6.16 |
5.13 |
2.88 |
0.86 |
| Other ethnicity |
1.70 |
-0.84 |
4.24 |
1.30 |
0.19 |
| Key worker |
-0.22 |
-0.80 |
0.35 |
0.29 |
0.44 |
| Time difference: Lockdown to baseline |
0.02 |
-0.12 |
0.17 |
0.07 |
0.76 |
| 2391 |
0.07 |
0.07 |
29.22 |
6.27e-34 |
6 |
OCIR retro
Regression: Change scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
-2.83 |
-6.89 |
1.22 |
2.07 |
0.17 |
| Anxiety disorders |
-2.22 |
-6.59 |
2.15 |
2.23 |
0.32 |
| Eating disorders |
-2.17 |
-8.85 |
4.52 |
3.41 |
0.53 |
| OCDs |
-3.45 |
-8.38 |
1.49 |
2.52 |
0.17 |
| PTSD |
-5.17 |
-11.03 |
0.70 |
2.99 |
0.08 |
| Depressive disorders |
-2.57 |
-6.64 |
1.51 |
2.08 |
0.22 |
| Bipolar disorders |
-2.82 |
-7.04 |
1.39 |
2.15 |
0.19 |
| 1833 |
0.00 |
0.00 |
0.62 |
0.71 |
6 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
-3.69 |
-6.52 |
-0.87 |
1.44 |
0.01 |
| Depressive and anxiety disorder |
-1.42 |
-4.27 |
1.44 |
1.46 |
0.33 |
| Only depressive disorder |
-1.99 |
-5.10 |
1.12 |
1.59 |
0.21 |
| Only anxiety disorder |
-2.05 |
-5.16 |
1.07 |
1.59 |
0.20 |
| Eating disorders |
0.14 |
-0.85 |
1.12 |
0.50 |
0.79 |
| OCDs |
-0.26 |
-1.11 |
0.58 |
0.43 |
0.54 |
| Psychotic and bipolar disorder |
0.76 |
-1.82 |
3.33 |
1.31 |
0.56 |
| Only psychotic disorder |
-0.04 |
-2.04 |
1.96 |
1.02 |
0.97 |
| Only bipolar disorder |
-0.26 |
-1.65 |
1.13 |
0.71 |
0.71 |
| PTSD |
-0.48 |
-1.31 |
0.36 |
0.43 |
0.26 |
| ASD |
-0.16 |
-1.97 |
1.65 |
0.92 |
0.86 |
| ADHD |
1.24 |
-1.46 |
3.93 |
1.37 |
0.37 |
| Personality disorder |
-0.75 |
-1.86 |
0.36 |
0.57 |
0.18 |
| 1833 |
0.00 |
0.00 |
0.62 |
0.71 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-3.49 |
-7.92 |
0.93 |
2.26 |
0.12 |
| Anxiety disorders |
-2.31 |
-6.67 |
2.05 |
2.22 |
0.30 |
| Eating disorders |
-2.07 |
-8.75 |
4.62 |
3.41 |
0.54 |
| OCDs |
-3.38 |
-8.31 |
1.54 |
2.51 |
0.18 |
| PTSD |
-5.32 |
-11.19 |
0.56 |
3.00 |
0.08 |
| Depressive disorders |
-2.85 |
-6.93 |
1.23 |
2.08 |
0.17 |
| Bipolar disorders |
-3.28 |
-7.50 |
0.95 |
2.15 |
0.13 |
| Female |
-0.46 |
-1.41 |
0.50 |
0.49 |
0.35 |
| Non-binary/Self-defined |
-0.20 |
-2.48 |
2.07 |
1.16 |
0.86 |
| age_category_collapsed_reordered16-18 |
0.31 |
-2.13 |
2.74 |
1.24 |
0.81 |
| 19-25 years |
-0.47 |
-1.60 |
0.67 |
0.58 |
0.42 |
| 36-45 years |
1.19 |
0.19 |
2.19 |
0.51 |
0.02 |
| 46-55 years |
0.98 |
0.00 |
1.96 |
0.50 |
0.05 |
| 56-65 years |
1.23 |
0.12 |
2.35 |
0.57 |
0.03 |
| 66-70 years |
2.37 |
0.14 |
4.61 |
1.14 |
0.04 |
| 71-75 years |
3.06 |
-0.17 |
6.28 |
1.64 |
0.06 |
| 76+ years |
2.11 |
-4.93 |
9.14 |
3.59 |
0.56 |
| Mixed or multiple ethnic origins |
2.32 |
0.22 |
4.42 |
1.07 |
0.03 |
| Asian or Asian British |
0.14 |
-4.10 |
4.38 |
2.16 |
0.95 |
| African or African British |
2.38 |
-3.90 |
8.66 |
3.20 |
0.46 |
| Other ethnicity |
1.30 |
-1.47 |
4.08 |
1.42 |
0.36 |
| Time difference: Lockdown to baseline |
0.08 |
-0.12 |
0.28 |
0.10 |
0.44 |
| 1833 |
0.00 |
0.00 |
0.62 |
0.71 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-4.07 |
-7.52 |
-0.62 |
1.76 |
0.02 |
| Depressive and anxiety disorder |
-1.65 |
-4.57 |
1.28 |
1.49 |
0.27 |
| Only depressive disorder |
-2.52 |
-5.69 |
0.66 |
1.62 |
0.12 |
| Only anxiety disorder |
-2.13 |
-5.29 |
1.03 |
1.61 |
0.19 |
| Eating disorders |
0.38 |
-0.61 |
1.37 |
0.51 |
0.45 |
| OCDs |
-0.15 |
-1.00 |
0.70 |
0.43 |
0.72 |
| Psychotic and bipolar disorder |
0.36 |
-2.21 |
2.94 |
1.31 |
0.78 |
| Only psychotic disorder |
-0.37 |
-2.38 |
1.63 |
1.02 |
0.71 |
| Only bipolar disorder |
-0.32 |
-1.72 |
1.08 |
0.72 |
0.66 |
| PTSD |
-0.46 |
-1.30 |
0.39 |
0.43 |
0.29 |
| ASD |
-0.06 |
-1.88 |
1.76 |
0.93 |
0.95 |
| ADHD |
1.36 |
-1.36 |
4.07 |
1.38 |
0.33 |
| Personality disorder |
-0.74 |
-1.85 |
0.37 |
0.57 |
0.19 |
| Female |
-0.76 |
-1.76 |
0.24 |
0.51 |
0.14 |
| Non-binary/Self-defined |
-0.82 |
-3.21 |
1.57 |
1.22 |
0.50 |
| age_category_collapsed_reordered16-18 |
0.51 |
-1.94 |
2.95 |
1.25 |
0.69 |
| 19-25 years |
-0.49 |
-1.65 |
0.68 |
0.59 |
0.41 |
| 36-45 years |
1.25 |
0.22 |
2.29 |
0.53 |
0.02 |
| 46-55 years |
0.96 |
-0.06 |
1.97 |
0.52 |
0.06 |
| 56-65 years |
1.09 |
-0.07 |
2.25 |
0.59 |
0.07 |
| 66-70 years |
2.26 |
-0.03 |
4.56 |
1.17 |
0.05 |
| 71-75 years |
2.89 |
-0.36 |
6.15 |
1.66 |
0.08 |
| 76+ years |
0.91 |
-7.26 |
9.09 |
4.17 |
0.83 |
| Mixed or multiple ethnic origins |
2.45 |
0.27 |
4.63 |
1.11 |
0.03 |
| Asian or Asian British |
-1.13 |
-5.85 |
3.58 |
2.40 |
0.64 |
| African or African British |
-0.51 |
-7.55 |
6.53 |
3.59 |
0.89 |
| Other ethnicity |
1.67 |
-1.24 |
4.57 |
1.48 |
0.26 |
| Key worker |
0.11 |
-0.60 |
0.83 |
0.37 |
0.75 |
| Time difference: Lockdown to baseline |
0.07 |
-0.14 |
0.27 |
0.11 |
0.54 |
| 1833 |
0.00 |
0.00 |
0.62 |
0.71 |
6 |
Regression: Absolute scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
1.58 |
-2.26 |
5.41 |
1.95 |
0.42 |
| ocir.sum_score_retro |
0.80 |
0.78 |
0.83 |
0.01 |
0.00e+00 |
| Anxiety disorders |
-3.74 |
-7.83 |
0.35 |
2.08 |
0.07 |
| Eating disorders |
-2.66 |
-8.91 |
3.60 |
3.19 |
0.41 |
| OCDs |
-2.11 |
-6.73 |
2.51 |
2.36 |
0.37 |
| PTSD |
-4.34 |
-9.82 |
1.15 |
2.80 |
0.12 |
| Depressive disorders |
-2.66 |
-6.47 |
1.15 |
1.94 |
0.17 |
| Bipolar disorders |
-1.92 |
-5.87 |
2.02 |
2.01 |
0.34 |
| 1833 |
0.71 |
0.71 |
644.81 |
0.00e+00 |
7 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
1.14 |
-1.55 |
3.83 |
1.37 |
0.41 |
| ocir.sum_score_retro |
0.78 |
0.76 |
0.81 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
-2.11 |
-4.77 |
0.55 |
1.35 |
0.12 |
| Only depressive disorder |
-3.03 |
-5.93 |
-0.14 |
1.48 |
0.04 |
| Only anxiety disorder |
-3.28 |
-6.18 |
-0.39 |
1.48 |
0.03 |
| Eating disorders |
0.29 |
-0.63 |
1.21 |
0.47 |
0.53 |
| OCDs |
1.45 |
0.63 |
2.26 |
0.41 |
5.00e-04 |
| Psychotic and bipolar disorder |
1.84 |
-0.56 |
4.24 |
1.22 |
0.13 |
| Only psychotic disorder |
0.37 |
-1.49 |
2.23 |
0.95 |
0.70 |
| Only bipolar disorder |
0.39 |
-0.91 |
1.68 |
0.66 |
0.56 |
| PTSD |
0.06 |
-0.72 |
0.84 |
0.40 |
0.87 |
| ASD |
1.15 |
-0.54 |
2.84 |
0.86 |
0.18 |
| ADHD |
1.06 |
-1.45 |
3.57 |
1.28 |
0.41 |
| Personality disorder |
0.25 |
-0.78 |
1.29 |
0.53 |
0.63 |
| 1837 |
0.03 |
0.03 |
8.98 |
1.08e-09 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
1.42 |
-2.94 |
5.77 |
2.22 |
0.52 |
| ocir.sum_score_retro |
0.80 |
0.78 |
0.83 |
0.01 |
0.00e+00 |
| Anxiety disorders |
-4.65 |
-8.89 |
-0.41 |
2.16 |
0.03 |
| Eating disorders |
-3.27 |
-9.62 |
3.09 |
3.24 |
0.31 |
| OCDs |
-2.94 |
-7.68 |
1.81 |
2.42 |
0.22 |
| PTSD |
-5.14 |
-10.76 |
0.47 |
2.86 |
0.07 |
| Depressive disorders |
-3.68 |
-7.67 |
0.31 |
2.03 |
0.07 |
| Bipolar disorders |
-2.92 |
-7.05 |
1.20 |
2.10 |
0.16 |
| Female |
-0.34 |
-1.23 |
0.55 |
0.46 |
0.46 |
| Non-binary/Self-defined |
0.23 |
-1.90 |
2.36 |
1.09 |
0.84 |
| age_category_collapsed_reordered16-18 |
0.87 |
-1.40 |
3.15 |
1.16 |
0.45 |
| 19-25 years |
-0.27 |
-1.33 |
0.80 |
0.54 |
0.62 |
| 36-45 years |
0.78 |
-0.16 |
1.72 |
0.48 |
0.10 |
| 46-55 years |
0.86 |
-0.06 |
1.77 |
0.47 |
0.07 |
| 56-65 years |
0.73 |
-0.32 |
1.78 |
0.53 |
0.17 |
| 66-70 years |
1.36 |
-0.75 |
3.47 |
1.07 |
0.21 |
| 71-75 years |
0.92 |
-2.11 |
3.95 |
1.54 |
0.55 |
| 76+ years |
1.61 |
-4.97 |
8.18 |
3.35 |
0.63 |
| Mixed or multiple ethnic origins |
1.96 |
-0.05 |
3.97 |
1.02 |
0.06 |
| Asian or Asian British |
2.24 |
-1.73 |
6.21 |
2.03 |
0.27 |
| African or African British |
3.24 |
-2.63 |
9.11 |
2.99 |
0.28 |
| Other ethnicity |
1.90 |
-0.75 |
4.54 |
1.35 |
0.16 |
| Key worker |
-0.41 |
-1.05 |
0.24 |
0.33 |
0.22 |
| Time difference: Lockdown to baseline |
0.15 |
-0.04 |
0.34 |
0.10 |
0.13 |
| 1837 |
0.03 |
0.03 |
8.98 |
1.08e-09 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
0.33 |
-2.93 |
3.58 |
1.66 |
0.84 |
| ocir.sum_score_retro |
0.78 |
0.76 |
0.81 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
-2.31 |
-5.03 |
0.41 |
1.39 |
0.10 |
| Only depressive disorder |
-3.37 |
-6.33 |
-0.42 |
1.51 |
0.03 |
| Only anxiety disorder |
-3.39 |
-6.33 |
-0.44 |
1.50 |
0.02 |
| Eating disorders |
0.47 |
-0.45 |
1.40 |
0.47 |
0.31 |
| OCDs |
1.51 |
0.70 |
2.33 |
0.42 |
2.85e-04 |
| Psychotic and bipolar disorder |
1.51 |
-0.90 |
3.91 |
1.22 |
0.22 |
| Only psychotic disorder |
0.06 |
-1.81 |
1.93 |
0.95 |
0.95 |
| Only bipolar disorder |
0.37 |
-0.94 |
1.68 |
0.67 |
0.58 |
| PTSD |
0.05 |
-0.74 |
0.84 |
0.40 |
0.91 |
| ASD |
1.08 |
-0.63 |
2.78 |
0.87 |
0.22 |
| ADHD |
1.06 |
-1.47 |
3.58 |
1.29 |
0.41 |
| Personality disorder |
0.20 |
-0.84 |
1.24 |
0.53 |
0.70 |
| Female |
-0.72 |
-1.65 |
0.22 |
0.48 |
0.13 |
| Non-binary/Self-defined |
-0.42 |
-2.64 |
1.81 |
1.13 |
0.71 |
| age_category_collapsed_reordered16-18 |
1.13 |
-1.15 |
3.42 |
1.16 |
0.33 |
| 19-25 years |
-0.16 |
-1.24 |
0.93 |
0.55 |
0.77 |
| 36-45 years |
0.91 |
-0.06 |
1.87 |
0.49 |
0.07 |
| 46-55 years |
1.03 |
0.09 |
1.98 |
0.48 |
0.03 |
| 56-65 years |
0.74 |
-0.34 |
1.82 |
0.55 |
0.18 |
| 66-70 years |
1.58 |
-0.55 |
3.72 |
1.09 |
0.15 |
| 71-75 years |
1.46 |
-1.57 |
4.50 |
1.55 |
0.34 |
| 76+ years |
0.83 |
-6.78 |
8.44 |
3.88 |
0.83 |
| Mixed or multiple ethnic origins |
1.94 |
-0.09 |
3.97 |
1.03 |
0.06 |
| Asian or Asian British |
1.47 |
-2.93 |
5.87 |
2.24 |
0.51 |
| African or African British |
0.05 |
-6.50 |
6.60 |
3.34 |
0.99 |
| Other ethnicity |
1.93 |
-0.77 |
4.63 |
1.38 |
0.16 |
| Key worker |
-0.24 |
-0.91 |
0.43 |
0.34 |
0.48 |
| Time difference: Lockdown to baseline |
0.15 |
-0.05 |
0.34 |
0.10 |
0.14 |
| 1837 |
0.03 |
0.03 |
8.98 |
1.08e-09 |
6 |
PCL baseline, not controlling for prior symptoms
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
8.44 |
8.35 |
8.54 |
0.05 |
0.00e+00 |
| Anxiety disorders |
3.49 |
3.24 |
3.74 |
0.13 |
9.52e-163 |
| Eating disorders |
3.57 |
2.77 |
4.37 |
0.41 |
2.26e-18 |
| OCDs |
5.56 |
4.91 |
6.20 |
0.33 |
3.78e-63 |
| PTSD |
6.26 |
5.62 |
6.89 |
0.32 |
7.90e-83 |
| Depressive disorders |
6.41 |
6.29 |
6.53 |
0.06 |
0.00e+00 |
| Bipolar disorders |
8.85 |
8.54 |
9.16 |
0.16 |
0.00e+00 |
| 32567 |
0.27 |
0.27 |
1987.28 |
0.00e+00 |
6 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
8.65 |
8.57 |
8.74 |
0.04 |
0.00e+00 |
| Depressive and anxiety disorder |
6.11 |
5.98 |
6.24 |
0.07 |
0.00e+00 |
| Only depressive disorder |
2.78 |
2.61 |
2.95 |
0.09 |
1.85e-216 |
| Only anxiety disorder |
3.28 |
3.06 |
3.50 |
0.11 |
6.19e-185 |
| Eating disorders |
1.34 |
1.11 |
1.57 |
0.12 |
5.16e-30 |
| OCDs |
1.74 |
1.52 |
1.97 |
0.11 |
1.82e-53 |
| Psychotic and bipolar disorder |
1.21 |
0.59 |
1.84 |
0.32 |
1.50e-04 |
| Only psychotic disorder |
0.72 |
0.19 |
1.26 |
0.27 |
0.008 |
| Only bipolar disorder |
1.16 |
0.82 |
1.50 |
0.17 |
1.61e-11 |
| PTSD |
2.86 |
2.65 |
3.06 |
0.10 |
7.16e-163 |
| ASD |
1.99 |
1.59 |
2.39 |
0.20 |
2.03e-22 |
| ADHD |
1.21 |
0.67 |
1.74 |
0.27 |
9.18e-06 |
| Personality disorder |
2.82 |
2.52 |
3.11 |
0.15 |
4.00e-78 |
| 32567 |
0.27 |
0.27 |
1987.28 |
0.00e+00 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
9.89 |
9.61 |
10.18 |
0.15 |
0.00e+00 |
| Anxiety disorders |
2.43 |
2.17 |
2.69 |
0.13 |
1.77e-75 |
| Eating disorders |
2.12 |
1.33 |
2.92 |
0.41 |
1.87e-07 |
| OCDs |
3.29 |
2.64 |
3.94 |
0.33 |
2.58e-23 |
| PTSD |
5.39 |
4.75 |
6.03 |
0.33 |
1.62e-60 |
| Depressive disorders |
5.34 |
5.20 |
5.47 |
0.07 |
0.00e+00 |
| Bipolar disorders |
7.67 |
7.36 |
7.98 |
0.16 |
0.00e+00 |
| Female |
0.77 |
0.63 |
0.91 |
0.07 |
1.06e-27 |
| Non-binary/Self-defined |
2.17 |
1.62 |
2.72 |
0.28 |
8.12e-15 |
| age_category_collapsed_reordered16-18 |
3.72 |
3.36 |
4.09 |
0.19 |
8.37e-87 |
| 19-25 years |
1.86 |
1.61 |
2.12 |
0.13 |
5.42e-47 |
| 36-45 years |
-0.73 |
-0.94 |
-0.52 |
0.11 |
1.10e-11 |
| 46-55 years |
-1.26 |
-1.45 |
-1.06 |
0.10 |
1.82e-36 |
| 56-65 years |
-2.17 |
-2.36 |
-1.97 |
0.10 |
1.37e-105 |
| 66-70 years |
-2.89 |
-3.14 |
-2.64 |
0.13 |
4.60e-115 |
| 71-75 years |
-3.05 |
-3.33 |
-2.76 |
0.15 |
9.12e-97 |
| 76+ years |
-2.92 |
-3.35 |
-2.49 |
0.22 |
6.93e-40 |
| Mixed or multiple ethnic origins |
0.56 |
0.12 |
1.00 |
0.22 |
0.01 |
| Asian or Asian British |
0.20 |
-0.34 |
0.74 |
0.28 |
0.46 |
| African or African British |
0.68 |
-0.30 |
1.66 |
0.50 |
0.17 |
| Other ethnicity |
1.02 |
0.27 |
1.78 |
0.38 |
0.008 |
| Time difference: Lockdown to baseline |
-0.01 |
-0.04 |
0.02 |
0.01 |
0.42 |
| 32567 |
0.27 |
0.27 |
1987.28 |
0.00e+00 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
9.96 |
9.68 |
10.24 |
0.14 |
0.00e+00 |
| Depressive and anxiety disorder |
5.22 |
5.08 |
5.36 |
0.07 |
0.00e+00 |
| Only depressive disorder |
2.64 |
2.46 |
2.82 |
0.09 |
5.39e-177 |
| Only anxiety disorder |
2.43 |
2.20 |
2.66 |
0.12 |
6.09e-95 |
| Eating disorders |
0.86 |
0.63 |
1.09 |
0.12 |
1.83e-13 |
| OCDs |
1.30 |
1.08 |
1.52 |
0.11 |
7.18e-31 |
| Psychotic and bipolar disorder |
1.44 |
0.82 |
2.06 |
0.32 |
4.85e-06 |
| Only psychotic disorder |
0.77 |
0.24 |
1.30 |
0.27 |
0.005 |
| Only bipolar disorder |
1.25 |
0.92 |
1.59 |
0.17 |
2.80e-13 |
| PTSD |
2.86 |
2.66 |
3.07 |
0.10 |
7.38e-163 |
| ASD |
1.07 |
0.67 |
1.47 |
0.21 |
1.95e-07 |
| ADHD |
0.60 |
0.07 |
1.13 |
0.27 |
0.03 |
| Personality disorder |
2.53 |
2.24 |
2.83 |
0.15 |
5.50e-64 |
| Female |
0.69 |
0.55 |
0.82 |
0.07 |
6.12e-24 |
| Non-binary/Self-defined |
1.20 |
0.66 |
1.73 |
0.27 |
1.12e-05 |
| age_category_collapsed_reordered16-18 |
3.78 |
3.43 |
4.13 |
0.18 |
6.03e-99 |
| 19-25 years |
1.74 |
1.49 |
1.98 |
0.12 |
5.45e-44 |
| 36-45 years |
-0.58 |
-0.79 |
-0.38 |
0.10 |
2.61e-08 |
| 46-55 years |
-0.86 |
-1.05 |
-0.67 |
0.10 |
1.09e-18 |
| 56-65 years |
-1.62 |
-1.81 |
-1.43 |
0.10 |
6.72e-62 |
| 66-70 years |
-2.37 |
-2.62 |
-2.12 |
0.13 |
4.25e-79 |
| 71-75 years |
-2.56 |
-2.84 |
-2.28 |
0.14 |
3.64e-71 |
| 76+ years |
-2.40 |
-2.82 |
-1.98 |
0.21 |
2.56e-29 |
| Mixed or multiple ethnic origins |
0.52 |
0.09 |
0.95 |
0.22 |
0.02 |
| Asian or Asian British |
0.77 |
0.26 |
1.28 |
0.26 |
0.003 |
| African or African British |
0.63 |
-0.29 |
1.56 |
0.47 |
0.18 |
| Other ethnicity |
0.84 |
0.10 |
1.59 |
0.38 |
0.03 |
| Key worker |
-0.55 |
-0.67 |
-0.42 |
0.06 |
4.00e-18 |
| Time difference: Lockdown to baseline |
-0.03 |
-0.05 |
0.00 |
0.01 |
0.07 |
| 32567 |
0.27 |
0.27 |
1987.28 |
0.00e+00 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
7.31 |
6.99 |
7.63 |
0.16 |
0.00e+00 |
| Anxiety disorders |
2.44 |
2.11 |
2.76 |
0.16 |
1.64e-49 |
| Eating disorders |
2.32 |
1.35 |
3.28 |
0.49 |
2.68e-06 |
| OCDs |
3.91 |
3.07 |
4.75 |
0.43 |
8.31e-20 |
| PTSD |
5.53 |
4.62 |
6.43 |
0.46 |
7.52e-33 |
| Depressive disorders |
5.73 |
5.56 |
5.89 |
0.08 |
0.00e+00 |
| Bipolar disorders |
7.95 |
7.60 |
8.31 |
0.18 |
0.00e+00 |
| Female |
0.54 |
0.38 |
0.69 |
0.08 |
1.40e-11 |
| Non-binary/Self-defined |
2.05 |
1.43 |
2.67 |
0.32 |
9.48e-11 |
| Age |
-233.98 |
-245.75 |
-222.21 |
6.00 |
1.94e-321 |
| Age^2 |
36.66 |
26.02 |
47.29 |
5.43 |
1.47e-11 |
| Mixed or multiple ethnic origins |
0.59 |
0.08 |
1.10 |
0.26 |
0.02 |
| Asian or Asian British |
0.61 |
-0.08 |
1.29 |
0.35 |
0.08 |
| African or African British |
0.86 |
-0.25 |
1.97 |
0.57 |
0.13 |
| Other ethnicity |
1.41 |
0.49 |
2.33 |
0.47 |
0.003 |
| Time difference: Lockdown to baseline |
0.13 |
0.09 |
0.17 |
0.02 |
3.13e-11 |
| 25270 |
0.31 |
0.31 |
1882.63 |
0.00e+00 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
7.59 |
7.28 |
7.90 |
0.16 |
0.00e+00 |
| Depressive and anxiety disorder |
5.70 |
5.53 |
5.87 |
0.09 |
0.00e+00 |
| Only depressive disorder |
2.94 |
2.72 |
3.15 |
0.11 |
4.51e-155 |
| Only anxiety disorder |
2.67 |
2.38 |
2.95 |
0.14 |
5.36e-75 |
| Eating disorders |
1.09 |
0.82 |
1.35 |
0.13 |
6.40e-16 |
| OCDs |
1.31 |
1.06 |
1.56 |
0.13 |
4.24e-24 |
| Psychotic and bipolar disorder |
1.06 |
0.32 |
1.81 |
0.38 |
0.005 |
| Only psychotic disorder |
0.44 |
-0.17 |
1.04 |
0.31 |
0.16 |
| Only bipolar disorder |
1.23 |
0.86 |
1.60 |
0.19 |
6.56e-11 |
| PTSD |
2.88 |
2.65 |
3.12 |
0.12 |
1.83e-125 |
| ASD |
1.36 |
0.88 |
1.85 |
0.25 |
3.67e-08 |
| ADHD |
0.64 |
-0.02 |
1.29 |
0.33 |
0.06 |
| Personality disorder |
2.48 |
2.14 |
2.81 |
0.17 |
5.13e-48 |
| Female |
0.41 |
0.26 |
0.56 |
0.08 |
7.45e-08 |
| Non-binary/Self-defined |
0.96 |
0.36 |
1.56 |
0.31 |
0.002 |
| Age |
-196.14 |
-208.00 |
-184.28 |
6.05 |
3.27e-225 |
| Age^2 |
24.22 |
13.67 |
34.77 |
5.38 |
6.83e-06 |
| Mixed or multiple ethnic origins |
0.46 |
-0.04 |
0.95 |
0.25 |
0.07 |
| Asian or Asian British |
1.05 |
0.40 |
1.69 |
0.33 |
0.001 |
| African or African British |
0.77 |
-0.28 |
1.82 |
0.54 |
0.15 |
| Other ethnicity |
1.08 |
0.17 |
1.99 |
0.46 |
0.02 |
| Key worker |
-0.58 |
-0.72 |
-0.44 |
0.07 |
3.46e-16 |
| Time difference: Lockdown to baseline |
0.13 |
0.09 |
0.17 |
0.02 |
1.19e-11 |
| 25270 |
0.31 |
0.31 |
1882.63 |
0.00e+00 |
6 |
PCL prepan
Regression: Change scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
0.28 |
-0.70 |
1.25 |
0.50 |
0.58 |
| Anxiety disorders |
-0.06 |
-1.14 |
1.02 |
0.55 |
0.92 |
| Eating disorders |
-0.66 |
-2.70 |
1.37 |
1.04 |
0.52 |
| OCDs |
-0.05 |
-1.48 |
1.39 |
0.73 |
0.95 |
| PTSD |
-1.68 |
-3.33 |
-0.02 |
0.84 |
0.05 |
| Depressive disorders |
-0.03 |
-1.01 |
0.96 |
0.50 |
0.96 |
| Bipolar disorders |
-0.24 |
-1.29 |
0.82 |
0.54 |
0.66 |
| 11874 |
0.00 |
0.00 |
1.20 |
0.30 |
6 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
0.39 |
-0.31 |
1.09 |
0.36 |
0.27 |
| Depressive and anxiety disorder |
0.02 |
-0.68 |
0.73 |
0.36 |
0.95 |
| Only depressive disorder |
-0.16 |
-0.92 |
0.61 |
0.39 |
0.69 |
| Only anxiety disorder |
-0.21 |
-1.01 |
0.59 |
0.41 |
0.61 |
| Eating disorders |
0.13 |
-0.21 |
0.48 |
0.18 |
0.45 |
| OCDs |
-0.08 |
-0.40 |
0.24 |
0.16 |
0.64 |
| Psychotic and bipolar disorder |
-0.69 |
-1.63 |
0.24 |
0.48 |
0.15 |
| Only psychotic disorder |
-0.03 |
-0.82 |
0.75 |
0.40 |
0.93 |
| Only bipolar disorder |
0.06 |
-0.41 |
0.53 |
0.24 |
0.79 |
| PTSD |
-0.89 |
-1.20 |
-0.59 |
0.15 |
7.68e-09 |
| ASD |
-0.12 |
-0.74 |
0.51 |
0.32 |
0.72 |
| ADHD |
-0.23 |
-1.09 |
0.63 |
0.44 |
0.60 |
| Personality disorder |
-0.29 |
-0.71 |
0.13 |
0.22 |
0.18 |
| 11874 |
0.00 |
0.00 |
1.20 |
0.30 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-0.42 |
-1.55 |
0.71 |
0.58 |
0.47 |
| Anxiety disorders |
-0.08 |
-1.16 |
1.00 |
0.55 |
0.89 |
| Eating disorders |
-0.77 |
-2.81 |
1.26 |
1.04 |
0.46 |
| OCDs |
-0.22 |
-1.65 |
1.21 |
0.73 |
0.76 |
| PTSD |
-1.69 |
-3.34 |
-0.03 |
0.85 |
0.05 |
| Depressive disorders |
0.03 |
-0.96 |
1.01 |
0.50 |
0.96 |
| Bipolar disorders |
-0.07 |
-1.12 |
0.98 |
0.54 |
0.90 |
| Female |
0.57 |
0.29 |
0.84 |
0.14 |
4.56e-05 |
| Non-binary/Self-defined |
0.06 |
-0.73 |
0.85 |
0.40 |
0.89 |
| age_category_collapsed_reordered16-18 |
-0.09 |
-0.77 |
0.60 |
0.35 |
0.81 |
| 19-25 years |
0.40 |
0.03 |
0.76 |
0.19 |
0.03 |
| 36-45 years |
-0.41 |
-0.72 |
-0.09 |
0.16 |
0.01 |
| 46-55 years |
-0.60 |
-0.91 |
-0.30 |
0.16 |
1.19e-04 |
| 56-65 years |
-0.30 |
-0.64 |
0.05 |
0.18 |
0.09 |
| 66-70 years |
-0.43 |
-1.02 |
0.17 |
0.31 |
0.16 |
| 71-75 years |
-0.40 |
-1.20 |
0.39 |
0.40 |
0.32 |
| 76+ years |
0.15 |
-1.32 |
1.62 |
0.75 |
0.84 |
| Mixed or multiple ethnic origins |
0.40 |
-0.31 |
1.11 |
0.36 |
0.27 |
| Asian or Asian British |
-0.18 |
-1.36 |
1.01 |
0.61 |
0.77 |
| African or African British |
-0.94 |
-2.80 |
0.92 |
0.95 |
0.32 |
| Other ethnicity |
-0.45 |
-1.52 |
0.61 |
0.54 |
0.40 |
| Time difference: Lockdown to baseline |
0.06 |
-0.01 |
0.12 |
0.03 |
0.07 |
| 11874 |
0.00 |
0.00 |
1.20 |
0.30 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-0.36 |
-1.28 |
0.56 |
0.47 |
0.44 |
| Depressive and anxiety disorder |
0.08 |
-0.64 |
0.79 |
0.36 |
0.83 |
| Only depressive disorder |
-0.03 |
-0.80 |
0.74 |
0.39 |
0.94 |
| Only anxiety disorder |
-0.23 |
-1.04 |
0.57 |
0.41 |
0.57 |
| Eating disorders |
0.00 |
-0.34 |
0.35 |
0.18 |
0.99 |
| OCDs |
-0.11 |
-0.44 |
0.21 |
0.16 |
0.49 |
| Psychotic and bipolar disorder |
-0.58 |
-1.52 |
0.35 |
0.48 |
0.22 |
| Only psychotic disorder |
0.07 |
-0.72 |
0.86 |
0.40 |
0.86 |
| Only bipolar disorder |
0.20 |
-0.27 |
0.67 |
0.24 |
0.41 |
| PTSD |
-0.87 |
-1.18 |
-0.57 |
0.16 |
1.90e-08 |
| ASD |
-0.12 |
-0.75 |
0.52 |
0.32 |
0.72 |
| ADHD |
-0.22 |
-1.08 |
0.64 |
0.44 |
0.62 |
| Personality disorder |
-0.44 |
-0.86 |
-0.01 |
0.22 |
0.04 |
| Female |
0.69 |
0.40 |
0.98 |
0.15 |
3.50e-06 |
| Non-binary/Self-defined |
0.17 |
-0.65 |
0.99 |
0.42 |
0.68 |
| age_category_collapsed_reordered16-18 |
-0.17 |
-0.85 |
0.51 |
0.35 |
0.62 |
| 19-25 years |
0.30 |
-0.07 |
0.67 |
0.19 |
0.12 |
| 36-45 years |
-0.45 |
-0.78 |
-0.13 |
0.17 |
0.007 |
| 46-55 years |
-0.55 |
-0.87 |
-0.23 |
0.16 |
8.29e-04 |
| 56-65 years |
-0.33 |
-0.69 |
0.04 |
0.18 |
0.08 |
| 66-70 years |
-0.63 |
-1.26 |
0.01 |
0.32 |
0.05 |
| 71-75 years |
-0.65 |
-1.49 |
0.19 |
0.43 |
0.13 |
| 76+ years |
0.11 |
-1.51 |
1.74 |
0.83 |
0.89 |
| Mixed or multiple ethnic origins |
0.45 |
-0.29 |
1.19 |
0.38 |
0.24 |
| Asian or Asian British |
0.22 |
-1.00 |
1.45 |
0.63 |
0.72 |
| African or African British |
-1.19 |
-3.10 |
0.72 |
0.97 |
0.22 |
| Other ethnicity |
0.11 |
-1.01 |
1.22 |
0.57 |
0.85 |
| Key worker |
-0.21 |
-0.44 |
0.01 |
0.11 |
0.06 |
| Time difference: Lockdown to baseline |
0.07 |
0.00 |
0.13 |
0.03 |
0.04 |
| 11874 |
0.00 |
0.00 |
1.20 |
0.30 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-0.66 |
-1.77 |
0.44 |
0.57 |
0.24 |
| Anxiety disorders |
-0.07 |
-1.15 |
1.01 |
0.55 |
0.90 |
| Eating disorders |
-0.83 |
-2.86 |
1.20 |
1.04 |
0.42 |
| OCDs |
-0.24 |
-1.67 |
1.19 |
0.73 |
0.74 |
| PTSD |
-1.68 |
-3.34 |
-0.02 |
0.85 |
0.05 |
| Depressive disorders |
0.04 |
-0.94 |
1.03 |
0.50 |
0.93 |
| Bipolar disorders |
-0.06 |
-1.11 |
0.99 |
0.54 |
0.91 |
| Female |
0.57 |
0.30 |
0.85 |
0.14 |
3.74e-05 |
| Non-binary/Self-defined |
0.07 |
-0.72 |
0.86 |
0.40 |
0.87 |
| Age |
-25.83 |
-37.44 |
-14.22 |
5.92 |
1.31e-05 |
| Age^2 |
17.47 |
6.11 |
28.84 |
5.80 |
0.003 |
| Mixed or multiple ethnic origins |
0.39 |
-0.31 |
1.10 |
0.36 |
0.28 |
| Asian or Asian British |
-0.19 |
-1.38 |
0.99 |
0.61 |
0.75 |
| African or African British |
-0.95 |
-2.81 |
0.91 |
0.95 |
0.32 |
| Other ethnicity |
-0.46 |
-1.53 |
0.61 |
0.54 |
0.40 |
| Time difference: Lockdown to baseline |
0.06 |
-0.01 |
0.12 |
0.03 |
0.08 |
| 11874 |
0.00 |
0.00 |
1.20 |
0.30 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-0.66 |
-1.55 |
0.23 |
0.45 |
0.15 |
| Depressive and anxiety disorder |
0.11 |
-0.60 |
0.82 |
0.36 |
0.76 |
| Only depressive disorder |
0.00 |
-0.77 |
0.77 |
0.39 |
1.00 |
| Only anxiety disorder |
-0.21 |
-1.01 |
0.60 |
0.41 |
0.61 |
| Eating disorders |
0.00 |
-0.35 |
0.34 |
0.18 |
0.99 |
| OCDs |
-0.12 |
-0.44 |
0.21 |
0.16 |
0.48 |
| Psychotic and bipolar disorder |
-0.57 |
-1.51 |
0.37 |
0.48 |
0.23 |
| Only psychotic disorder |
0.05 |
-0.73 |
0.84 |
0.40 |
0.90 |
| Only bipolar disorder |
0.19 |
-0.28 |
0.67 |
0.24 |
0.42 |
| PTSD |
-0.88 |
-1.19 |
-0.58 |
0.16 |
1.42e-08 |
| ASD |
-0.15 |
-0.78 |
0.48 |
0.32 |
0.64 |
| ADHD |
-0.23 |
-1.09 |
0.63 |
0.44 |
0.60 |
| Personality disorder |
-0.42 |
-0.85 |
0.00 |
0.22 |
0.05 |
| Female |
0.69 |
0.40 |
0.98 |
0.15 |
2.71e-06 |
| Non-binary/Self-defined |
0.19 |
-0.63 |
1.01 |
0.42 |
0.65 |
| Age |
-25.48 |
-37.77 |
-13.20 |
6.27 |
4.80e-05 |
| Age^2 |
11.30 |
-0.94 |
23.54 |
6.25 |
0.07 |
| Mixed or multiple ethnic origins |
0.45 |
-0.30 |
1.19 |
0.38 |
0.24 |
| Asian or Asian British |
0.21 |
-1.02 |
1.43 |
0.63 |
0.74 |
| African or African British |
-1.20 |
-3.11 |
0.71 |
0.97 |
0.22 |
| Other ethnicity |
0.10 |
-1.02 |
1.21 |
0.57 |
0.87 |
| Key worker |
-0.21 |
-0.43 |
0.01 |
0.11 |
0.07 |
| Time difference: Lockdown to baseline |
0.07 |
0.00 |
0.13 |
0.03 |
0.04 |
| 11874 |
0.00 |
0.00 |
1.20 |
0.30 |
6 |
Regression: Absolute scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
6.09 |
5.20 |
6.98 |
0.45 |
1.24e-40 |
| pcl.sum_score_prepan |
0.57 |
0.55 |
0.58 |
0.01 |
0.00e+00 |
| Anxiety disorders |
-0.32 |
-1.28 |
0.64 |
0.49 |
0.51 |
| Eating disorders |
-0.18 |
-1.99 |
1.63 |
0.92 |
0.85 |
| OCDs |
0.51 |
-0.76 |
1.79 |
0.65 |
0.43 |
| PTSD |
0.03 |
-1.43 |
1.50 |
0.75 |
0.97 |
| Depressive disorders |
0.87 |
-0.01 |
1.74 |
0.45 |
0.05 |
| Bipolar disorders |
1.40 |
0.47 |
2.34 |
0.48 |
0.003 |
| 11874 |
0.33 |
0.32 |
817.59 |
0.00e+00 |
7 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
6.83 |
6.17 |
7.48 |
0.33 |
7.35e-91 |
| pcl.sum_score_prepan |
0.53 |
0.52 |
0.55 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
0.51 |
-0.12 |
1.13 |
0.32 |
0.11 |
| Only depressive disorder |
-0.51 |
-1.19 |
0.16 |
0.34 |
0.14 |
| Only anxiety disorder |
-0.63 |
-1.34 |
0.08 |
0.36 |
0.08 |
| Eating disorders |
0.59 |
0.29 |
0.89 |
0.16 |
1.40e-04 |
| OCDs |
0.61 |
0.33 |
0.90 |
0.15 |
2.59e-05 |
| Psychotic and bipolar disorder |
-0.40 |
-1.23 |
0.42 |
0.42 |
0.34 |
| Only psychotic disorder |
-0.05 |
-0.74 |
0.65 |
0.35 |
0.89 |
| Only bipolar disorder |
0.35 |
-0.07 |
0.76 |
0.21 |
0.10 |
| PTSD |
0.73 |
0.46 |
1.01 |
0.14 |
1.43e-07 |
| ASD |
0.65 |
0.10 |
1.20 |
0.28 |
0.02 |
| ADHD |
0.24 |
-0.51 |
1.00 |
0.39 |
0.53 |
| Personality disorder |
1.08 |
0.71 |
1.46 |
0.19 |
1.71e-08 |
| 11940 |
0.01 |
0.01 |
30.02 |
6.05e-36 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
5.79 |
4.77 |
6.81 |
0.52 |
1.43e-28 |
| pcl.sum_score_prepan |
0.54 |
0.52 |
0.55 |
0.01 |
0.00e+00 |
| Anxiety disorders |
-0.35 |
-1.30 |
0.60 |
0.48 |
0.47 |
| Eating disorders |
-0.23 |
-2.01 |
1.56 |
0.91 |
0.80 |
| OCDs |
0.22 |
-1.04 |
1.48 |
0.64 |
0.73 |
| PTSD |
0.40 |
-1.06 |
1.86 |
0.74 |
0.59 |
| Depressive disorders |
1.08 |
0.21 |
1.94 |
0.44 |
0.02 |
| Bipolar disorders |
1.75 |
0.82 |
2.68 |
0.47 |
2.27e-04 |
| Female |
0.57 |
0.33 |
0.81 |
0.12 |
2.94e-06 |
| Non-binary/Self-defined |
0.84 |
0.15 |
1.54 |
0.35 |
0.02 |
| age_category_collapsed_reordered16-18 |
1.07 |
0.47 |
1.68 |
0.31 |
4.75e-04 |
| 19-25 years |
0.89 |
0.57 |
1.21 |
0.16 |
5.85e-08 |
| 36-45 years |
-0.47 |
-0.74 |
-0.19 |
0.14 |
9.59e-04 |
| 46-55 years |
-0.70 |
-0.97 |
-0.43 |
0.14 |
3.17e-07 |
| 56-65 years |
-0.97 |
-1.28 |
-0.67 |
0.16 |
3.99e-10 |
| 66-70 years |
-1.99 |
-2.53 |
-1.46 |
0.27 |
2.90e-13 |
| 71-75 years |
-2.37 |
-3.07 |
-1.67 |
0.36 |
4.06e-11 |
| 76+ years |
-2.21 |
-3.50 |
-0.92 |
0.66 |
7.85e-04 |
| Mixed or multiple ethnic origins |
0.33 |
-0.29 |
0.96 |
0.32 |
0.30 |
| Asian or Asian British |
0.15 |
-0.90 |
1.19 |
0.53 |
0.79 |
| African or African British |
0.06 |
-1.57 |
1.69 |
0.83 |
0.94 |
| Other ethnicity |
0.16 |
-0.78 |
1.10 |
0.48 |
0.73 |
| Key worker |
-0.66 |
-0.85 |
-0.47 |
0.10 |
7.14e-12 |
| Time difference: Lockdown to baseline |
0.09 |
0.04 |
0.15 |
0.03 |
9.23e-04 |
| 11940 |
0.01 |
0.01 |
30.02 |
6.05e-36 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
6.46 |
5.62 |
7.30 |
0.43 |
5.67e-51 |
| pcl.sum_score_prepan |
0.51 |
0.50 |
0.53 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
0.70 |
0.07 |
1.32 |
0.32 |
0.03 |
| Only depressive disorder |
-0.13 |
-0.80 |
0.55 |
0.34 |
0.71 |
| Only anxiety disorder |
-0.64 |
-1.35 |
0.06 |
0.36 |
0.07 |
| Eating disorders |
0.43 |
0.12 |
0.73 |
0.15 |
0.006 |
| OCDs |
0.52 |
0.23 |
0.80 |
0.14 |
3.53e-04 |
| Psychotic and bipolar disorder |
-0.19 |
-1.01 |
0.63 |
0.42 |
0.65 |
| Only psychotic disorder |
0.04 |
-0.65 |
0.72 |
0.35 |
0.92 |
| Only bipolar disorder |
0.51 |
0.10 |
0.93 |
0.21 |
0.01 |
| PTSD |
0.85 |
0.57 |
1.12 |
0.14 |
1.20e-09 |
| ASD |
0.37 |
-0.19 |
0.92 |
0.28 |
0.19 |
| ADHD |
0.16 |
-0.59 |
0.91 |
0.38 |
0.68 |
| Personality disorder |
0.92 |
0.55 |
1.30 |
0.19 |
1.43e-06 |
| Female |
0.47 |
0.21 |
0.72 |
0.13 |
3.21e-04 |
| Non-binary/Self-defined |
0.47 |
-0.25 |
1.18 |
0.36 |
0.20 |
| age_category_collapsed_reordered16-18 |
1.18 |
0.58 |
1.78 |
0.31 |
1.12e-04 |
| 19-25 years |
0.87 |
0.54 |
1.19 |
0.17 |
2.18e-07 |
| 36-45 years |
-0.48 |
-0.77 |
-0.19 |
0.15 |
0.001 |
| 46-55 years |
-0.57 |
-0.85 |
-0.29 |
0.14 |
6.43e-05 |
| 56-65 years |
-0.78 |
-1.10 |
-0.46 |
0.16 |
1.33e-06 |
| 66-70 years |
-1.84 |
-2.39 |
-1.28 |
0.28 |
8.75e-11 |
| 71-75 years |
-2.22 |
-2.95 |
-1.48 |
0.38 |
3.86e-09 |
| 76+ years |
-1.76 |
-3.19 |
-0.34 |
0.73 |
0.02 |
| Mixed or multiple ethnic origins |
0.24 |
-0.41 |
0.89 |
0.33 |
0.47 |
| Asian or Asian British |
0.52 |
-0.55 |
1.60 |
0.55 |
0.34 |
| African or African British |
-0.02 |
-1.69 |
1.65 |
0.85 |
0.98 |
| Other ethnicity |
0.35 |
-0.63 |
1.32 |
0.50 |
0.49 |
| Key worker |
-0.59 |
-0.79 |
-0.40 |
0.10 |
2.64e-09 |
| Time difference: Lockdown to baseline |
0.09 |
0.04 |
0.15 |
0.03 |
0.001 |
| 11940 |
0.01 |
0.01 |
30.02 |
6.05e-36 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
5.43 |
4.43 |
6.43 |
0.51 |
2.81e-26 |
| pcl.sum_score_prepan |
0.54 |
0.53 |
0.56 |
0.01 |
0.00e+00 |
| Anxiety disorders |
-0.37 |
-1.32 |
0.58 |
0.48 |
0.45 |
| Eating disorders |
-0.30 |
-2.09 |
1.48 |
0.91 |
0.74 |
| OCDs |
0.22 |
-1.04 |
1.48 |
0.64 |
0.73 |
| PTSD |
0.31 |
-1.14 |
1.77 |
0.74 |
0.67 |
| Depressive disorders |
1.04 |
0.17 |
1.91 |
0.44 |
0.02 |
| Bipolar disorders |
1.70 |
0.77 |
2.63 |
0.47 |
3.51e-04 |
| Female |
0.56 |
0.32 |
0.80 |
0.12 |
4.16e-06 |
| Non-binary/Self-defined |
0.85 |
0.16 |
1.54 |
0.35 |
0.02 |
| Age |
-79.27 |
-89.66 |
-68.88 |
5.30 |
3.91e-50 |
| Age^2 |
2.83 |
-7.45 |
13.10 |
5.24 |
0.59 |
| Mixed or multiple ethnic origins |
0.31 |
-0.31 |
0.94 |
0.32 |
0.33 |
| Asian or Asian British |
0.15 |
-0.90 |
1.19 |
0.53 |
0.78 |
| African or African British |
0.05 |
-1.58 |
1.68 |
0.83 |
0.95 |
| Other ethnicity |
0.17 |
-0.77 |
1.11 |
0.48 |
0.72 |
| Key worker |
-0.67 |
-0.86 |
-0.48 |
0.10 |
3.99e-12 |
| Time difference: Lockdown to baseline |
0.10 |
0.04 |
0.15 |
0.03 |
8.12e-04 |
| 11940 |
0.01 |
0.01 |
30.02 |
6.05e-36 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
6.14 |
5.33 |
6.96 |
0.41 |
2.72e-49 |
| pcl.sum_score_prepan |
0.51 |
0.50 |
0.53 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
0.66 |
0.03 |
1.28 |
0.32 |
0.04 |
| Only depressive disorder |
-0.14 |
-0.82 |
0.53 |
0.34 |
0.68 |
| Only anxiety disorder |
-0.67 |
-1.37 |
0.04 |
0.36 |
0.06 |
| Eating disorders |
0.43 |
0.13 |
0.74 |
0.15 |
0.005 |
| OCDs |
0.51 |
0.23 |
0.79 |
0.14 |
4.12e-04 |
| Psychotic and bipolar disorder |
-0.17 |
-0.99 |
0.66 |
0.42 |
0.69 |
| Only psychotic disorder |
0.04 |
-0.65 |
0.72 |
0.35 |
0.92 |
| Only bipolar disorder |
0.50 |
0.09 |
0.91 |
0.21 |
0.02 |
| PTSD |
0.85 |
0.57 |
1.12 |
0.14 |
1.17e-09 |
| ASD |
0.39 |
-0.16 |
0.94 |
0.28 |
0.17 |
| ADHD |
0.10 |
-0.65 |
0.86 |
0.38 |
0.79 |
| Personality disorder |
0.88 |
0.51 |
1.26 |
0.19 |
4.03e-06 |
| Female |
0.46 |
0.21 |
0.71 |
0.13 |
3.88e-04 |
| Non-binary/Self-defined |
0.47 |
-0.24 |
1.19 |
0.36 |
0.19 |
| Age |
-71.24 |
-82.10 |
-60.38 |
5.54 |
1.45e-37 |
| Age^2 |
6.03 |
-4.69 |
16.75 |
5.47 |
0.27 |
| Mixed or multiple ethnic origins |
0.23 |
-0.42 |
0.88 |
0.33 |
0.50 |
| Asian or Asian British |
0.52 |
-0.56 |
1.59 |
0.55 |
0.35 |
| African or African British |
-0.03 |
-1.70 |
1.64 |
0.85 |
0.97 |
| Other ethnicity |
0.33 |
-0.65 |
1.31 |
0.50 |
0.51 |
| Key worker |
-0.60 |
-0.79 |
-0.40 |
0.10 |
2.46e-09 |
| Time difference: Lockdown to baseline |
0.10 |
0.04 |
0.15 |
0.03 |
0.001 |
| 11940 |
0.01 |
0.01 |
30.02 |
6.05e-36 |
6 |
SENSITIVITY based on highest level of education
GAD prepan
Regression: Absolute scores
GAD baseline
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
6.51 |
6.17 |
6.85 |
0.17 |
4.16e-303 |
| Depressive and anxiety disorder |
4.54 |
4.39 |
4.68 |
0.07 |
0.00e+00 |
| Only depressive disorder |
1.83 |
1.65 |
2.02 |
0.10 |
5.27e-82 |
| Only anxiety disorder |
3.05 |
2.82 |
3.29 |
0.12 |
2.00e-141 |
| Eating disorders |
0.92 |
0.69 |
1.16 |
0.12 |
1.63e-14 |
| OCDs |
1.43 |
1.20 |
1.65 |
0.12 |
9.22e-35 |
| Psychotic and bipolar disorder |
0.65 |
0.01 |
1.29 |
0.33 |
0.05 |
| Only psychotic disorder |
0.46 |
-0.09 |
1.01 |
0.28 |
0.10 |
| Only bipolar disorder |
0.62 |
0.27 |
0.96 |
0.18 |
4.47e-04 |
| PTSD |
1.53 |
1.31 |
1.74 |
0.11 |
1.13e-45 |
| ASD |
1.37 |
0.96 |
1.78 |
0.21 |
7.67e-11 |
| ADHD |
0.44 |
-0.10 |
0.98 |
0.28 |
0.11 |
| Personality disorder |
1.69 |
1.39 |
1.99 |
0.15 |
5.48e-28 |
| Female |
0.96 |
0.82 |
1.10 |
0.07 |
3.16e-42 |
| Non-binary/Self-defined |
0.70 |
0.16 |
1.24 |
0.28 |
0.01 |
| age_category_collapsed_reordered16-18 |
2.72 |
2.35 |
3.09 |
0.19 |
6.72e-46 |
| age_category_collapsed_reordered19-25 |
1.55 |
1.30 |
1.80 |
0.13 |
3.62e-34 |
| age_category_collapsed_reordered36-45 |
-0.71 |
-0.92 |
-0.50 |
0.11 |
2.26e-11 |
| age_category_collapsed_reordered46-55 |
-1.32 |
-1.52 |
-1.13 |
0.10 |
6.80e-40 |
| age_category_collapsed_reordered56-65 |
-2.22 |
-2.42 |
-2.03 |
0.10 |
1.74e-107 |
| age_category_collapsed_reordered66-70 |
-3.14 |
-3.40 |
-2.89 |
0.13 |
9.40e-127 |
| age_category_collapsed_reordered71-75 |
-3.35 |
-3.65 |
-3.06 |
0.15 |
1.82e-107 |
| age_category_collapsed_reordered76+ |
-3.25 |
-3.70 |
-2.80 |
0.23 |
1.10e-44 |
| Mixed or multiple ethnic origins |
0.11 |
-0.33 |
0.54 |
0.22 |
0.62 |
| Asian or Asian British |
0.15 |
-0.37 |
0.67 |
0.26 |
0.57 |
| African or African British |
-0.45 |
-1.40 |
0.50 |
0.49 |
0.35 |
| Other ethnicity |
0.93 |
0.16 |
1.71 |
0.39 |
0.02 |
| Key worker |
-0.30 |
-0.43 |
-0.18 |
0.06 |
2.81e-06 |
| Time difference: Lockdown to baseline |
-0.26 |
-0.28 |
-0.23 |
0.01 |
1.10e-67 |
| Highest education NVQ |
-0.45 |
-0.73 |
-0.16 |
0.15 |
0.002 |
| Highest education A-Levels |
-0.56 |
-0.77 |
-0.35 |
0.11 |
1.56e-07 |
| Highest education University |
-1.00 |
-1.19 |
-0.81 |
0.10 |
1.10e-25 |
| 32679 |
0.21 |
0.21 |
1485.53 |
0.00e+00 |
6 |
GAD retro
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
4.05 |
3.76 |
4.35 |
0.15 |
3.89e-157 |
| gad.sum_score_retro |
0.65 |
0.64 |
0.66 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
2.49 |
2.35 |
2.63 |
0.07 |
2.68e-273 |
| Only depressive disorder |
1.07 |
0.91 |
1.23 |
0.08 |
4.92e-38 |
| Only anxiety disorder |
1.82 |
1.61 |
2.02 |
0.10 |
3.27e-67 |
| Eating disorders |
0.49 |
0.29 |
0.70 |
0.10 |
2.73e-06 |
| OCDs |
0.45 |
0.26 |
0.65 |
0.10 |
7.35e-06 |
| Psychotic and bipolar disorder |
0.29 |
-0.27 |
0.86 |
0.29 |
0.30 |
| Only psychotic disorder |
0.18 |
-0.31 |
0.67 |
0.25 |
0.47 |
| Only bipolar disorder |
0.32 |
0.01 |
0.62 |
0.16 |
0.04 |
| PTSD |
0.75 |
0.57 |
0.93 |
0.09 |
1.41e-15 |
| ASD |
0.67 |
0.31 |
1.03 |
0.18 |
2.49e-04 |
| ADHD |
0.12 |
-0.35 |
0.59 |
0.24 |
0.62 |
| Personality disorder |
0.57 |
0.30 |
0.83 |
0.13 |
2.36e-05 |
| Female |
0.81 |
0.69 |
0.93 |
0.06 |
5.29e-40 |
| Non-binary/Self-defined |
0.10 |
-0.37 |
0.57 |
0.24 |
0.67 |
| age_category_collapsed_reordered16-18 |
0.83 |
0.51 |
1.15 |
0.16 |
4.29e-07 |
| age_category_collapsed_reordered19-25 |
0.92 |
0.71 |
1.14 |
0.11 |
2.94e-17 |
| age_category_collapsed_reordered36-45 |
-0.53 |
-0.71 |
-0.35 |
0.09 |
9.20e-09 |
| age_category_collapsed_reordered46-55 |
-0.89 |
-1.06 |
-0.72 |
0.09 |
1.53e-24 |
| age_category_collapsed_reordered56-65 |
-1.29 |
-1.46 |
-1.12 |
0.09 |
5.12e-49 |
| age_category_collapsed_reordered66-70 |
-1.81 |
-2.04 |
-1.59 |
0.11 |
1.96e-57 |
| age_category_collapsed_reordered71-75 |
-2.00 |
-2.26 |
-1.74 |
0.13 |
2.04e-52 |
| age_category_collapsed_reordered76+ |
-2.07 |
-2.46 |
-1.68 |
0.20 |
2.21e-25 |
| Mixed or multiple ethnic origins |
-0.24 |
-0.61 |
0.14 |
0.19 |
0.21 |
| Asian or Asian British |
-0.14 |
-0.58 |
0.31 |
0.23 |
0.55 |
| African or African British |
-0.68 |
-1.50 |
0.13 |
0.42 |
0.10 |
| Other ethnicity |
0.55 |
-0.12 |
1.23 |
0.34 |
0.11 |
| Key worker |
0.05 |
-0.06 |
0.16 |
0.06 |
0.38 |
| Time difference: Lockdown to baseline |
-0.22 |
-0.24 |
-0.19 |
0.01 |
3.06e-65 |
| Highest education NVQ |
-0.26 |
-0.51 |
-0.01 |
0.13 |
0.04 |
| Highest education A-Levels |
-0.28 |
-0.46 |
-0.10 |
0.09 |
0.002 |
| Highest education University |
-0.39 |
-0.55 |
-0.23 |
0.08 |
2.15e-06 |
| 30973 |
0.25 |
0.25 |
1678.24 |
0.00e+00 |
6 |
GAD prepan
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
3.10 |
2.17 |
4.03 |
0.47 |
6.34e-11 |
| pcl.sum_score_prepan |
0.36 |
0.35 |
0.38 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
0.93 |
0.29 |
1.57 |
0.33 |
0.004 |
| Only depressive disorder |
-0.82 |
-1.52 |
-0.13 |
0.35 |
0.02 |
| Only anxiety disorder |
0.76 |
0.03 |
1.48 |
0.37 |
0.04 |
| Eating disorders |
0.79 |
0.48 |
1.11 |
0.16 |
6.88e-07 |
| OCDs |
0.84 |
0.55 |
1.14 |
0.15 |
1.68e-08 |
| Psychotic and bipolar disorder |
-0.32 |
-1.17 |
0.53 |
0.43 |
0.46 |
| Only psychotic disorder |
0.09 |
-0.62 |
0.80 |
0.36 |
0.81 |
| Only bipolar disorder |
0.18 |
-0.25 |
0.60 |
0.22 |
0.42 |
| PTSD |
0.13 |
-0.15 |
0.41 |
0.14 |
0.36 |
| ASD |
0.79 |
0.22 |
1.36 |
0.29 |
0.007 |
| ADHD |
-0.04 |
-0.81 |
0.73 |
0.39 |
0.92 |
| Personality disorder |
0.58 |
0.19 |
0.96 |
0.20 |
0.004 |
| Female |
0.54 |
0.28 |
0.80 |
0.13 |
5.05e-05 |
| Non-binary/Self-defined |
0.19 |
-0.54 |
0.92 |
0.37 |
0.61 |
| age_category_collapsed_reordered16-18 |
1.04 |
0.41 |
1.68 |
0.32 |
0.001 |
| age_category_collapsed_reordered19-25 |
1.00 |
0.67 |
1.34 |
0.17 |
5.06e-09 |
| age_category_collapsed_reordered36-45 |
-0.49 |
-0.79 |
-0.20 |
0.15 |
9.84e-04 |
| age_category_collapsed_reordered46-55 |
-0.91 |
-1.20 |
-0.62 |
0.15 |
6.51e-10 |
| age_category_collapsed_reordered56-65 |
-1.67 |
-2.00 |
-1.34 |
0.17 |
3.81e-23 |
| age_category_collapsed_reordered66-70 |
-2.38 |
-2.96 |
-1.79 |
0.30 |
1.64e-15 |
| age_category_collapsed_reordered71-75 |
-2.62 |
-3.41 |
-1.83 |
0.40 |
8.53e-11 |
| age_category_collapsed_reordered76+ |
-2.32 |
-3.81 |
-0.83 |
0.76 |
0.002 |
| Mixed or multiple ethnic origins |
0.01 |
-0.65 |
0.67 |
0.34 |
0.98 |
| Asian or Asian British |
-0.07 |
-1.17 |
1.03 |
0.56 |
0.90 |
| African or African British |
-0.90 |
-2.68 |
0.87 |
0.91 |
0.32 |
| Other ethnicity |
0.85 |
-0.17 |
1.87 |
0.52 |
0.10 |
| Key worker |
-0.25 |
-0.45 |
-0.05 |
0.10 |
0.02 |
| Time difference: Lockdown to baseline |
0.00 |
-0.06 |
0.06 |
0.03 |
0.95 |
| Highest education NVQ |
-0.18 |
-0.66 |
0.30 |
0.24 |
0.47 |
| Highest education A-Levels |
-0.90 |
-1.28 |
-0.51 |
0.20 |
5.25e-06 |
| Highest education University |
-1.15 |
-1.51 |
-0.79 |
0.18 |
3.38e-10 |
| 12028 |
0.00 |
0.00 |
8.99 |
7.92e-10 |
6 |
PHQ baseline
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
7.69 |
7.31 |
8.07 |
0.19 |
0.00e+00 |
| Depressive and anxiety disorder |
5.50 |
5.33 |
5.66 |
0.08 |
0.00e+00 |
| Only depressive disorder |
3.43 |
3.22 |
3.64 |
0.11 |
7.32e-220 |
| Only anxiety disorder |
2.03 |
1.77 |
2.30 |
0.14 |
5.41e-51 |
| Eating disorders |
1.59 |
1.33 |
1.86 |
0.14 |
6.57e-32 |
| OCDs |
1.35 |
1.10 |
1.61 |
0.13 |
3.69e-25 |
| Psychotic and bipolar disorder |
0.45 |
-0.27 |
1.18 |
0.37 |
0.22 |
| Only psychotic disorder |
0.88 |
0.26 |
1.49 |
0.32 |
0.006 |
| Only bipolar disorder |
1.44 |
1.05 |
1.83 |
0.20 |
3.51e-13 |
| PTSD |
2.05 |
1.82 |
2.29 |
0.12 |
2.33e-64 |
| ASD |
1.54 |
1.08 |
2.01 |
0.24 |
7.69e-11 |
| ADHD |
1.01 |
0.40 |
1.62 |
0.31 |
0.001 |
| Personality disorder |
2.86 |
2.52 |
3.20 |
0.17 |
1.67e-60 |
| Female |
0.85 |
0.69 |
1.00 |
0.08 |
1.16e-26 |
| Non-binary/Self-defined |
1.38 |
0.76 |
1.99 |
0.31 |
1.12e-05 |
| age_category_collapsed_reordered16-18 |
5.01 |
4.59 |
5.43 |
0.21 |
3.79e-119 |
| age_category_collapsed_reordered19-25 |
2.04 |
1.76 |
2.32 |
0.14 |
7.27e-46 |
| age_category_collapsed_reordered36-45 |
-0.68 |
-0.91 |
-0.44 |
0.12 |
1.72e-08 |
| age_category_collapsed_reordered46-55 |
-1.09 |
-1.31 |
-0.87 |
0.11 |
3.32e-22 |
| age_category_collapsed_reordered56-65 |
-2.19 |
-2.41 |
-1.97 |
0.11 |
1.15e-82 |
| age_category_collapsed_reordered66-70 |
-3.41 |
-3.70 |
-3.13 |
0.15 |
3.51e-118 |
| age_category_collapsed_reordered71-75 |
-3.54 |
-3.87 |
-3.20 |
0.17 |
1.40e-94 |
| age_category_collapsed_reordered76+ |
-3.42 |
-3.93 |
-2.91 |
0.26 |
4.03e-39 |
| Mixed or multiple ethnic origins |
0.38 |
-0.11 |
0.87 |
0.25 |
0.13 |
| Asian or Asian British |
0.33 |
-0.25 |
0.92 |
0.30 |
0.27 |
| African or African British |
-0.31 |
-1.39 |
0.76 |
0.55 |
0.57 |
| Other ethnicity |
0.99 |
0.12 |
1.86 |
0.45 |
0.03 |
| Key worker |
-0.60 |
-0.74 |
-0.46 |
0.07 |
1.07e-16 |
| Time difference: Lockdown to baseline |
-0.24 |
-0.27 |
-0.21 |
0.02 |
1.33e-46 |
| Highest education NVQ |
-0.70 |
-1.03 |
-0.38 |
0.16 |
1.71e-05 |
| Highest education A-Levels |
-0.62 |
-0.86 |
-0.39 |
0.12 |
2.12e-07 |
| Highest education University |
-1.44 |
-1.65 |
-1.23 |
0.11 |
4.70e-41 |
| 32662 |
0.25 |
0.25 |
1854.75 |
0.00e+00 |
6 |
PHQ retro
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
4.72 |
4.40 |
5.04 |
0.16 |
9.69e-183 |
| phq.sum_score_retro |
0.67 |
0.66 |
0.68 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
2.77 |
2.62 |
2.92 |
0.08 |
7.05e-290 |
| Only depressive disorder |
1.77 |
1.60 |
1.95 |
0.09 |
4.60e-86 |
| Only anxiety disorder |
1.23 |
1.01 |
1.45 |
0.11 |
3.91e-28 |
| Eating disorders |
0.77 |
0.54 |
0.99 |
0.11 |
1.28e-11 |
| OCDs |
0.43 |
0.22 |
0.65 |
0.11 |
7.11e-05 |
| Psychotic and bipolar disorder |
-0.15 |
-0.76 |
0.45 |
0.31 |
0.62 |
| Only psychotic disorder |
0.12 |
-0.40 |
0.65 |
0.27 |
0.65 |
| Only bipolar disorder |
0.66 |
0.33 |
0.99 |
0.17 |
8.34e-05 |
| PTSD |
1.00 |
0.80 |
1.20 |
0.10 |
5.44e-23 |
| ASD |
0.69 |
0.31 |
1.08 |
0.20 |
4.55e-04 |
| ADHD |
0.25 |
-0.26 |
0.76 |
0.26 |
0.33 |
| Personality disorder |
0.95 |
0.67 |
1.24 |
0.14 |
4.46e-11 |
| Female |
0.74 |
0.61 |
0.86 |
0.07 |
3.04e-29 |
| Non-binary/Self-defined |
0.48 |
-0.02 |
0.98 |
0.26 |
0.06 |
| age_category_collapsed_reordered16-18 |
2.68 |
2.34 |
3.03 |
0.18 |
6.00e-52 |
| age_category_collapsed_reordered19-25 |
1.22 |
0.99 |
1.45 |
0.12 |
2.12e-25 |
| age_category_collapsed_reordered36-45 |
-0.56 |
-0.76 |
-0.37 |
0.10 |
1.82e-08 |
| age_category_collapsed_reordered46-55 |
-0.79 |
-0.97 |
-0.61 |
0.09 |
2.25e-17 |
| age_category_collapsed_reordered56-65 |
-1.33 |
-1.51 |
-1.14 |
0.09 |
5.52e-45 |
| age_category_collapsed_reordered66-70 |
-1.92 |
-2.16 |
-1.68 |
0.12 |
8.36e-56 |
| age_category_collapsed_reordered71-75 |
-2.07 |
-2.34 |
-1.79 |
0.14 |
3.34e-48 |
| age_category_collapsed_reordered76+ |
-2.10 |
-2.52 |
-1.68 |
0.22 |
1.64e-22 |
| Mixed or multiple ethnic origins |
0.05 |
-0.35 |
0.46 |
0.20 |
0.79 |
| Asian or Asian British |
-0.02 |
-0.49 |
0.46 |
0.24 |
0.95 |
| African or African British |
-0.46 |
-1.34 |
0.41 |
0.45 |
0.30 |
| Other ethnicity |
0.36 |
-0.36 |
1.09 |
0.37 |
0.33 |
| Key worker |
-0.05 |
-0.17 |
0.07 |
0.06 |
0.40 |
| Time difference: Lockdown to baseline |
-0.22 |
-0.25 |
-0.19 |
0.01 |
2.64e-58 |
| Highest education NVQ |
-0.42 |
-0.69 |
-0.15 |
0.14 |
0.002 |
| Highest education A-Levels |
-0.31 |
-0.50 |
-0.12 |
0.10 |
0.002 |
| Highest education University |
-0.57 |
-0.74 |
-0.39 |
0.09 |
1.72e-10 |
| 30959 |
0.28 |
0.28 |
2029.98 |
0.00e+00 |
6 |
PHQ prepan
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
4.09 |
3.05 |
5.12 |
0.53 |
1.05e-14 |
| pcl.sum_score_prepan |
0.43 |
0.41 |
0.45 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
1.17 |
0.45 |
1.88 |
0.36 |
0.001 |
| Only depressive disorder |
1.00 |
0.23 |
1.78 |
0.39 |
0.01 |
| Only anxiety disorder |
-1.07 |
-1.88 |
-0.27 |
0.41 |
0.009 |
| Eating disorders |
1.41 |
1.06 |
1.76 |
0.18 |
2.67e-15 |
| OCDs |
0.71 |
0.38 |
1.03 |
0.17 |
2.23e-05 |
| Psychotic and bipolar disorder |
-0.57 |
-1.52 |
0.38 |
0.48 |
0.24 |
| Only psychotic disorder |
0.38 |
-0.41 |
1.18 |
0.41 |
0.34 |
| Only bipolar disorder |
0.76 |
0.29 |
1.23 |
0.24 |
0.002 |
| PTSD |
0.18 |
-0.14 |
0.49 |
0.16 |
0.27 |
| ASD |
0.74 |
0.10 |
1.38 |
0.33 |
0.02 |
| ADHD |
0.14 |
-0.72 |
1.00 |
0.44 |
0.75 |
| Personality disorder |
1.37 |
0.93 |
1.80 |
0.22 |
5.87e-10 |
| Female |
0.12 |
-0.17 |
0.41 |
0.15 |
0.41 |
| Non-binary/Self-defined |
0.53 |
-0.28 |
1.35 |
0.42 |
0.20 |
| age_category_collapsed_reordered16-18 |
2.39 |
1.68 |
3.10 |
0.36 |
3.66e-11 |
| age_category_collapsed_reordered19-25 |
1.32 |
0.95 |
1.69 |
0.19 |
4.80e-12 |
| age_category_collapsed_reordered36-45 |
-0.44 |
-0.77 |
-0.11 |
0.17 |
0.008 |
| age_category_collapsed_reordered46-55 |
-0.60 |
-0.92 |
-0.28 |
0.16 |
2.76e-04 |
| age_category_collapsed_reordered56-65 |
-1.46 |
-1.83 |
-1.10 |
0.19 |
6.73e-15 |
| age_category_collapsed_reordered66-70 |
-2.91 |
-3.56 |
-2.26 |
0.33 |
2.14e-18 |
| age_category_collapsed_reordered71-75 |
-3.22 |
-4.10 |
-2.34 |
0.45 |
6.95e-13 |
| age_category_collapsed_reordered76+ |
-2.65 |
-4.33 |
-0.97 |
0.86 |
0.002 |
| Mixed or multiple ethnic origins |
0.37 |
-0.37 |
1.10 |
0.38 |
0.33 |
| Asian or Asian British |
-0.06 |
-1.29 |
1.16 |
0.62 |
0.92 |
| African or African British |
-0.71 |
-2.69 |
1.27 |
1.01 |
0.48 |
| Other ethnicity |
0.45 |
-0.68 |
1.59 |
0.58 |
0.44 |
| Key worker |
-0.72 |
-0.94 |
-0.49 |
0.11 |
3.85e-10 |
| Time difference: Lockdown to baseline |
0.05 |
-0.02 |
0.11 |
0.03 |
0.16 |
| Highest education NVQ |
-0.24 |
-0.78 |
0.29 |
0.27 |
0.38 |
| Highest education A-Levels |
-0.96 |
-1.39 |
-0.53 |
0.22 |
1.33e-05 |
| Highest education University |
-1.56 |
-1.96 |
-1.16 |
0.20 |
2.42e-14 |
| 12024 |
0.02 |
0.02 |
41.62 |
1.65e-50 |
6 |
OCIR baseline
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
18.75 |
16.87 |
20.63 |
0.96 |
4.94e-82 |
| Depressive and anxiety disorder |
3.14 |
2.24 |
4.04 |
0.46 |
1.13e-11 |
| Only depressive disorder |
0.36 |
-0.85 |
1.57 |
0.62 |
0.56 |
| Only anxiety disorder |
0.82 |
-0.43 |
2.06 |
0.64 |
0.20 |
| Eating disorders |
0.37 |
-0.70 |
1.44 |
0.54 |
0.50 |
| OCDs |
7.03 |
6.09 |
7.97 |
0.48 |
9.11e-48 |
| Psychotic and bipolar disorder |
7.05 |
4.47 |
9.62 |
1.32 |
8.91e-08 |
| Only psychotic disorder |
4.27 |
1.97 |
6.57 |
1.17 |
2.73e-04 |
| Only bipolar disorder |
2.81 |
1.15 |
4.47 |
0.85 |
8.89e-04 |
| PTSD |
2.07 |
1.14 |
3.01 |
0.48 |
1.41e-05 |
| ASD |
7.45 |
5.74 |
9.17 |
0.87 |
1.75e-17 |
| ADHD |
2.35 |
0.01 |
4.69 |
1.19 |
0.05 |
| Personality disorder |
2.85 |
1.57 |
4.13 |
0.65 |
1.24e-05 |
| Female |
-0.88 |
-1.81 |
0.04 |
0.47 |
0.06 |
| Non-binary/Self-defined |
-1.03 |
-3.53 |
1.47 |
1.27 |
0.42 |
| age_category_collapsed_reordered16-18 |
6.38 |
4.71 |
8.05 |
0.85 |
7.40e-14 |
| age_category_collapsed_reordered19-25 |
1.52 |
0.29 |
2.75 |
0.63 |
0.02 |
| age_category_collapsed_reordered36-45 |
-0.14 |
-1.29 |
1.02 |
0.59 |
0.82 |
| age_category_collapsed_reordered46-55 |
-0.26 |
-1.33 |
0.81 |
0.55 |
0.63 |
| age_category_collapsed_reordered56-65 |
-1.36 |
-2.44 |
-0.27 |
0.55 |
0.01 |
| age_category_collapsed_reordered66-70 |
-1.33 |
-2.94 |
0.29 |
0.82 |
0.11 |
| age_category_collapsed_reordered71-75 |
-2.33 |
-4.33 |
-0.34 |
1.02 |
0.02 |
| age_category_collapsed_reordered76+ |
-3.89 |
-7.58 |
-0.19 |
1.89 |
0.04 |
| Mixed or multiple ethnic origins |
0.66 |
-1.54 |
2.85 |
1.12 |
0.56 |
| Asian or Asian British |
5.40 |
2.54 |
8.27 |
1.46 |
2.16e-04 |
| African or African British |
1.20 |
-4.67 |
7.08 |
3.00 |
0.69 |
| Other ethnicity |
2.84 |
-0.30 |
5.98 |
1.60 |
0.08 |
| Key worker |
-0.81 |
-1.52 |
-0.10 |
0.36 |
0.02 |
| Time difference: Lockdown to baseline |
-0.44 |
-0.59 |
-0.29 |
0.08 |
2.58e-08 |
| Highest education NVQ |
-1.05 |
-2.97 |
0.88 |
0.98 |
0.29 |
| Highest education A-Levels |
-2.06 |
-3.15 |
-0.96 |
0.56 |
2.46e-04 |
| Highest education University |
-3.17 |
-4.19 |
-2.14 |
0.52 |
1.34e-09 |
| 5506 |
0.05 |
0.05 |
52.82 |
1.41e-63 |
6 |
OCIR retro
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
14.27 |
12.75 |
15.78 |
0.77 |
8.64e-73 |
| ocir.sum_score_retro |
0.74 |
0.72 |
0.77 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
-1.20 |
-1.94 |
-0.46 |
0.38 |
0.001 |
| Only depressive disorder |
-0.91 |
-1.90 |
0.08 |
0.51 |
0.07 |
| Only anxiety disorder |
-0.39 |
-1.41 |
0.62 |
0.52 |
0.45 |
| Eating disorders |
-0.11 |
-0.94 |
0.73 |
0.43 |
0.80 |
| OCDs |
2.16 |
1.42 |
2.90 |
0.38 |
1.19e-08 |
| Psychotic and bipolar disorder |
4.15 |
2.14 |
6.16 |
1.03 |
5.37e-05 |
| Only psychotic disorder |
1.49 |
-0.28 |
3.25 |
0.90 |
0.10 |
| Only bipolar disorder |
0.43 |
-0.81 |
1.68 |
0.63 |
0.50 |
| PTSD |
0.62 |
-0.10 |
1.34 |
0.37 |
0.09 |
| ASD |
2.43 |
1.06 |
3.79 |
0.70 |
5.04e-04 |
| ADHD |
1.74 |
-0.14 |
3.62 |
0.96 |
0.07 |
| Personality disorder |
0.66 |
-0.31 |
1.64 |
0.50 |
0.18 |
| Female |
0.10 |
-0.63 |
0.83 |
0.37 |
0.79 |
| Non-binary/Self-defined |
-0.58 |
-2.54 |
1.38 |
1.00 |
0.56 |
| age_category_collapsed_reordered16-18 |
4.44 |
3.03 |
5.85 |
0.72 |
6.98e-10 |
| age_category_collapsed_reordered19-25 |
0.14 |
-0.83 |
1.11 |
0.49 |
0.77 |
| age_category_collapsed_reordered36-45 |
0.21 |
-0.67 |
1.10 |
0.45 |
0.64 |
| age_category_collapsed_reordered46-55 |
0.24 |
-0.59 |
1.07 |
0.42 |
0.57 |
| age_category_collapsed_reordered56-65 |
0.98 |
0.13 |
1.84 |
0.44 |
0.02 |
| age_category_collapsed_reordered66-70 |
1.31 |
0.03 |
2.60 |
0.66 |
0.05 |
| age_category_collapsed_reordered71-75 |
1.02 |
-0.60 |
2.64 |
0.83 |
0.22 |
| age_category_collapsed_reordered76+ |
-1.84 |
-5.23 |
1.56 |
1.73 |
0.29 |
| Mixed or multiple ethnic origins |
1.20 |
-0.51 |
2.90 |
0.87 |
0.17 |
| Asian or Asian British |
3.60 |
1.15 |
6.05 |
1.25 |
0.004 |
| African or African British |
-1.12 |
-6.03 |
3.80 |
2.51 |
0.66 |
| Other ethnicity |
0.54 |
-1.83 |
2.90 |
1.21 |
0.66 |
| Key worker |
-0.36 |
-0.91 |
0.19 |
0.28 |
0.20 |
| Time difference: Lockdown to baseline |
-1.33 |
-1.46 |
-1.21 |
0.06 |
1.86e-96 |
| Highest education NVQ |
-3.74 |
-5.16 |
-2.31 |
0.73 |
3.03e-07 |
| Highest education A-Levels |
-1.92 |
-2.80 |
-1.04 |
0.45 |
2.04e-05 |
| Highest education University |
-1.38 |
-2.20 |
-0.57 |
0.42 |
8.90e-04 |
| 5455 |
0.06 |
0.05 |
53.30 |
3.86e-64 |
6 |
OCIR prepan
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
8.66 |
2.93 |
14.38 |
2.92 |
0.003 |
| pcl.sum_score_prepan |
0.61 |
0.51 |
0.70 |
0.05 |
3.45e-35 |
| Depressive and anxiety disorder |
-4.64 |
-8.98 |
-0.29 |
2.22 |
0.04 |
| Only depressive disorder |
-5.24 |
-9.97 |
-0.52 |
2.41 |
0.03 |
| Only anxiety disorder |
-6.10 |
-10.81 |
-1.39 |
2.40 |
0.01 |
| Eating disorders |
0.54 |
-0.99 |
2.06 |
0.78 |
0.49 |
| OCDs |
7.14 |
5.82 |
8.46 |
0.67 |
1.55e-25 |
| Psychotic and bipolar disorder |
6.00 |
1.88 |
10.12 |
2.10 |
0.004 |
| Only psychotic disorder |
1.32 |
-1.74 |
4.39 |
1.56 |
0.40 |
| Only bipolar disorder |
1.87 |
-0.34 |
4.07 |
1.12 |
0.10 |
| PTSD |
-0.22 |
-1.55 |
1.11 |
0.68 |
0.74 |
| ASD |
4.60 |
1.74 |
7.46 |
1.46 |
0.002 |
| ADHD |
0.32 |
-3.94 |
4.59 |
2.17 |
0.88 |
| Personality disorder |
1.55 |
-0.18 |
3.29 |
0.88 |
0.08 |
| Female |
-0.12 |
-1.66 |
1.42 |
0.79 |
0.88 |
| Non-binary/Self-defined |
1.38 |
-2.26 |
5.02 |
1.86 |
0.46 |
| age_category_collapsed_reordered16-18 |
1.13 |
-2.70 |
4.96 |
1.95 |
0.56 |
| age_category_collapsed_reordered19-25 |
0.61 |
-1.16 |
2.38 |
0.90 |
0.50 |
| age_category_collapsed_reordered36-45 |
-0.84 |
-2.43 |
0.76 |
0.81 |
0.30 |
| age_category_collapsed_reordered46-55 |
0.32 |
-1.23 |
1.88 |
0.79 |
0.68 |
| age_category_collapsed_reordered56-65 |
-1.33 |
-3.13 |
0.46 |
0.91 |
0.14 |
| age_category_collapsed_reordered66-70 |
-0.32 |
-3.84 |
3.20 |
1.79 |
0.86 |
| age_category_collapsed_reordered71-75 |
-2.00 |
-7.05 |
3.06 |
2.58 |
0.44 |
| age_category_collapsed_reordered76+ |
1.27 |
-9.51 |
12.04 |
5.49 |
0.82 |
| Mixed or multiple ethnic origins |
1.46 |
-1.85 |
4.78 |
1.69 |
0.39 |
| Asian or Asian British |
6.57 |
-1.05 |
14.19 |
3.89 |
0.09 |
| African or African British |
2.37 |
-8.32 |
13.05 |
5.45 |
0.66 |
| Other ethnicity |
3.28 |
-1.14 |
7.70 |
2.25 |
0.15 |
| Key worker |
-0.75 |
-1.85 |
0.35 |
0.56 |
0.18 |
| Time difference: Lockdown to baseline |
0.28 |
-0.04 |
0.60 |
0.16 |
0.09 |
| Highest education NVQ |
0.78 |
-1.71 |
3.27 |
1.27 |
0.54 |
| Highest education A-Levels |
-1.86 |
-3.83 |
0.10 |
1.00 |
0.06 |
| Highest education University |
-2.67 |
-4.52 |
-0.83 |
0.94 |
0.004 |
| 1873 |
0.03 |
0.03 |
9.40 |
3.43e-10 |
6 |
PCL baseline
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
10.62 |
10.29 |
10.96 |
0.17 |
0.00e+00 |
| Depressive and anxiety disorder |
5.16 |
5.01 |
5.30 |
0.07 |
0.00e+00 |
| Only depressive disorder |
2.64 |
2.46 |
2.83 |
0.09 |
1.39e-170 |
| Only anxiety disorder |
2.43 |
2.20 |
2.66 |
0.12 |
2.42e-92 |
| Eating disorders |
0.91 |
0.68 |
1.15 |
0.12 |
1.79e-14 |
| OCDs |
1.24 |
1.02 |
1.47 |
0.11 |
3.03e-27 |
| Psychotic and bipolar disorder |
1.31 |
0.67 |
1.94 |
0.32 |
5.21e-05 |
| Only psychotic disorder |
0.77 |
0.22 |
1.31 |
0.28 |
0.006 |
| Only bipolar disorder |
1.23 |
0.89 |
1.57 |
0.17 |
1.98e-12 |
| PTSD |
2.83 |
2.62 |
3.04 |
0.11 |
5.98e-154 |
| ASD |
1.08 |
0.68 |
1.49 |
0.21 |
2.00e-07 |
| ADHD |
0.55 |
0.01 |
1.09 |
0.28 |
0.05 |
| Personality disorder |
2.43 |
2.13 |
2.73 |
0.15 |
6.97e-57 |
| Female |
0.70 |
0.57 |
0.84 |
0.07 |
4.79e-24 |
| Non-binary/Self-defined |
1.24 |
0.70 |
1.78 |
0.27 |
6.53e-06 |
| age_category_collapsed_reordered16-18 |
3.36 |
2.99 |
3.73 |
0.19 |
2.75e-70 |
| age_category_collapsed_reordered19-25 |
1.70 |
1.46 |
1.95 |
0.13 |
1.26e-41 |
| age_category_collapsed_reordered36-45 |
-0.63 |
-0.84 |
-0.43 |
0.11 |
2.00e-09 |
| age_category_collapsed_reordered46-55 |
-0.98 |
-1.18 |
-0.79 |
0.10 |
3.03e-23 |
| age_category_collapsed_reordered56-65 |
-1.77 |
-1.97 |
-1.58 |
0.10 |
1.39e-70 |
| age_category_collapsed_reordered66-70 |
-2.49 |
-2.74 |
-2.24 |
0.13 |
2.42e-82 |
| age_category_collapsed_reordered71-75 |
-2.65 |
-2.94 |
-2.36 |
0.15 |
1.64e-69 |
| age_category_collapsed_reordered76+ |
-2.45 |
-2.90 |
-2.00 |
0.23 |
1.08e-26 |
| Mixed or multiple ethnic origins |
0.57 |
0.14 |
1.00 |
0.22 |
0.010 |
| Asian or Asian British |
0.69 |
0.17 |
1.20 |
0.26 |
0.009 |
| African or African British |
0.57 |
-0.37 |
1.51 |
0.48 |
0.24 |
| Other ethnicity |
0.80 |
0.03 |
1.56 |
0.39 |
0.04 |
| Key worker |
-0.50 |
-0.62 |
-0.37 |
0.06 |
4.24e-15 |
| Time difference: Lockdown to baseline |
-0.04 |
-0.06 |
-0.01 |
0.01 |
0.01 |
| Highest education NVQ |
-0.16 |
-0.44 |
0.12 |
0.14 |
0.27 |
| Highest education A-Levels |
-0.32 |
-0.53 |
-0.11 |
0.11 |
0.002 |
| Highest education University |
-0.71 |
-0.90 |
-0.53 |
0.09 |
3.79e-14 |
| 32567 |
0.27 |
0.27 |
1987.28 |
0.00e+00 |
6 |
#PCL prepan ### Model 1b: Overlapping disorders, Adjusted Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
7.36 |
6.44 |
8.27 |
0.47 |
4.36e-55 |
| pcl.sum_score_prepan |
0.50 |
0.49 |
0.52 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
0.65 |
0.01 |
1.28 |
0.32 |
0.05 |
| Only depressive disorder |
-0.18 |
-0.86 |
0.51 |
0.35 |
0.62 |
| Only anxiety disorder |
-0.66 |
-1.37 |
0.06 |
0.36 |
0.07 |
| Eating disorders |
0.50 |
0.19 |
0.81 |
0.16 |
0.001 |
| OCDs |
0.49 |
0.20 |
0.77 |
0.15 |
9.24e-04 |
| Psychotic and bipolar disorder |
-0.18 |
-1.01 |
0.66 |
0.43 |
0.68 |
| Only psychotic disorder |
0.00 |
-0.70 |
0.71 |
0.36 |
0.99 |
| Only bipolar disorder |
0.57 |
0.15 |
0.99 |
0.21 |
0.008 |
| PTSD |
0.81 |
0.54 |
1.09 |
0.14 |
8.79e-09 |
| ASD |
0.34 |
-0.22 |
0.91 |
0.29 |
0.23 |
| ADHD |
0.16 |
-0.61 |
0.93 |
0.39 |
0.68 |
| Personality disorder |
0.90 |
0.51 |
1.28 |
0.19 |
4.40e-06 |
| Female |
0.44 |
0.18 |
0.70 |
0.13 |
8.13e-04 |
| Non-binary/Self-defined |
0.45 |
-0.27 |
1.17 |
0.37 |
0.22 |
| age_category_collapsed_reordered16-18 |
1.02 |
0.40 |
1.65 |
0.32 |
0.001 |
| age_category_collapsed_reordered19-25 |
0.90 |
0.57 |
1.23 |
0.17 |
1.04e-07 |
| age_category_collapsed_reordered36-45 |
-0.54 |
-0.83 |
-0.25 |
0.15 |
2.68e-04 |
| age_category_collapsed_reordered46-55 |
-0.67 |
-0.95 |
-0.38 |
0.15 |
4.29e-06 |
| age_category_collapsed_reordered56-65 |
-0.96 |
-1.28 |
-0.63 |
0.17 |
7.86e-09 |
| age_category_collapsed_reordered66-70 |
-1.81 |
-2.39 |
-1.23 |
0.30 |
8.82e-10 |
| age_category_collapsed_reordered71-75 |
-2.32 |
-3.10 |
-1.54 |
0.40 |
5.57e-09 |
| age_category_collapsed_reordered76+ |
-2.10 |
-3.56 |
-0.64 |
0.75 |
0.005 |
| Mixed or multiple ethnic origins |
0.34 |
-0.31 |
0.99 |
0.33 |
0.31 |
| Asian or Asian British |
0.47 |
-0.62 |
1.56 |
0.56 |
0.40 |
| African or African British |
-0.20 |
-1.95 |
1.54 |
0.89 |
0.82 |
| Other ethnicity |
0.28 |
-0.72 |
1.29 |
0.51 |
0.58 |
| Key worker |
-0.53 |
-0.73 |
-0.33 |
0.10 |
1.40e-07 |
| Time difference: Lockdown to baseline |
0.09 |
0.03 |
0.15 |
0.03 |
0.003 |
| Highest education NVQ |
-0.06 |
-0.54 |
0.41 |
0.24 |
0.80 |
| Highest education A-Levels |
-0.64 |
-1.02 |
-0.26 |
0.19 |
0.001 |
| Highest education University |
-0.79 |
-1.14 |
-0.44 |
0.18 |
1.21e-05 |
| 11940 |
0.01 |
0.01 |
30.02 |
6.05e-36 |
6 |
Sensitivity anlayses based on employment prior to covid
Function change to include employment prior to covid as predictors
GAD baseline
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
5.43 |
5.14 |
5.72 |
0.15 |
2.91e-293 |
| Depressive and anxiety disorder |
4.39 |
4.25 |
4.54 |
0.07 |
0.00e+00 |
| Only depressive disorder |
1.75 |
1.57 |
1.93 |
0.09 |
2.07e-78 |
| Only anxiety disorder |
3.00 |
2.77 |
3.23 |
0.12 |
1.19e-141 |
| Eating disorders |
0.97 |
0.73 |
1.21 |
0.12 |
2.53e-15 |
| OCDs |
1.36 |
1.13 |
1.59 |
0.12 |
6.45e-31 |
| Psychotic and bipolar disorder |
0.98 |
0.31 |
1.65 |
0.34 |
0.004 |
| Only psychotic disorder |
0.22 |
-0.35 |
0.78 |
0.29 |
0.45 |
| Only bipolar disorder |
0.47 |
0.11 |
0.83 |
0.18 |
0.010 |
| PTSD |
1.44 |
1.22 |
1.66 |
0.11 |
6.78e-39 |
| ASD |
1.26 |
0.84 |
1.68 |
0.22 |
5.77e-09 |
| ADHD |
0.42 |
-0.14 |
0.97 |
0.28 |
0.14 |
| Personality disorder |
1.43 |
1.11 |
1.75 |
0.16 |
2.02e-18 |
| Female |
0.92 |
0.79 |
1.06 |
0.07 |
4.13e-41 |
| Non-binary/Self-defined |
0.70 |
0.15 |
1.25 |
0.28 |
0.01 |
| age_category_collapsed_reordered16-18 |
3.09 |
2.71 |
3.47 |
0.19 |
6.20e-57 |
| age_category_collapsed_reordered19-25 |
1.57 |
1.32 |
1.83 |
0.13 |
8.14e-34 |
| age_category_collapsed_reordered36-45 |
-0.77 |
-0.99 |
-0.56 |
0.11 |
6.49e-13 |
| age_category_collapsed_reordered46-55 |
-1.30 |
-1.50 |
-1.10 |
0.10 |
1.46e-38 |
| age_category_collapsed_reordered56-65 |
-2.00 |
-2.20 |
-1.79 |
0.11 |
4.99e-80 |
| age_category_collapsed_reordered66-70 |
-2.61 |
-2.90 |
-2.32 |
0.15 |
6.07e-70 |
| age_category_collapsed_reordered71-75 |
-2.84 |
-3.16 |
-2.51 |
0.17 |
8.40e-66 |
| age_category_collapsed_reordered76+ |
-2.70 |
-3.15 |
-2.25 |
0.23 |
5.08e-32 |
| Mixed or multiple ethnic origins |
0.15 |
-0.28 |
0.59 |
0.22 |
0.48 |
| Asian or Asian British |
0.05 |
-0.46 |
0.56 |
0.26 |
0.85 |
| African or African British |
-0.41 |
-1.38 |
0.55 |
0.49 |
0.40 |
| Other ethnicity |
0.74 |
-0.02 |
1.51 |
0.39 |
0.06 |
| Time difference: Lockdown to baseline |
-0.25 |
-0.28 |
-0.22 |
0.01 |
6.45e-67 |
| Key worker |
0.05 |
-0.09 |
0.20 |
0.07 |
0.47 |
| Retired |
-0.19 |
-0.40 |
0.02 |
0.11 |
0.08 |
| Student |
0.60 |
0.27 |
0.92 |
0.16 |
2.77e-04 |
| Unemployed |
1.80 |
1.54 |
2.07 |
0.13 |
2.33e-41 |
| 32679 |
0.21 |
0.21 |
1485.53 |
0.00e+00 |
6 |
GAD retro
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
3.64 |
3.39 |
3.88 |
0.13 |
5.83e-177 |
| gad.sum_score_retro |
0.66 |
0.65 |
0.67 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
2.41 |
2.27 |
2.54 |
0.07 |
2.00e-262 |
| Only depressive disorder |
1.02 |
0.86 |
1.18 |
0.08 |
1.50e-36 |
| Only anxiety disorder |
1.76 |
1.56 |
1.97 |
0.10 |
4.85e-66 |
| Eating disorders |
0.55 |
0.34 |
0.76 |
0.11 |
2.52e-07 |
| OCDs |
0.47 |
0.27 |
0.68 |
0.10 |
4.01e-06 |
| Psychotic and bipolar disorder |
0.72 |
0.14 |
1.30 |
0.30 |
0.02 |
| Only psychotic disorder |
0.00 |
-0.50 |
0.50 |
0.25 |
1.00 |
| Only bipolar disorder |
0.32 |
0.00 |
0.64 |
0.16 |
0.05 |
| PTSD |
0.77 |
0.58 |
0.96 |
0.10 |
1.49e-15 |
| ASD |
0.65 |
0.28 |
1.02 |
0.19 |
5.64e-04 |
| ADHD |
0.10 |
-0.39 |
0.58 |
0.25 |
0.70 |
| Personality disorder |
0.44 |
0.17 |
0.72 |
0.14 |
0.002 |
| Female |
0.78 |
0.66 |
0.89 |
0.06 |
3.12e-39 |
| Non-binary/Self-defined |
0.13 |
-0.34 |
0.60 |
0.24 |
0.59 |
| age_category_collapsed_reordered16-18 |
0.89 |
0.56 |
1.21 |
0.17 |
9.99e-08 |
| age_category_collapsed_reordered19-25 |
0.89 |
0.67 |
1.11 |
0.11 |
1.03e-15 |
| age_category_collapsed_reordered36-45 |
-0.57 |
-0.75 |
-0.39 |
0.09 |
9.59e-10 |
| age_category_collapsed_reordered46-55 |
-0.87 |
-1.04 |
-0.70 |
0.09 |
1.10e-23 |
| age_category_collapsed_reordered56-65 |
-1.19 |
-1.37 |
-1.01 |
0.09 |
3.65e-39 |
| age_category_collapsed_reordered66-70 |
-1.58 |
-1.83 |
-1.33 |
0.13 |
2.29e-35 |
| age_category_collapsed_reordered71-75 |
-1.78 |
-2.06 |
-1.50 |
0.14 |
9.33e-36 |
| age_category_collapsed_reordered76+ |
-1.82 |
-2.20 |
-1.43 |
0.20 |
2.57e-20 |
| Mixed or multiple ethnic origins |
-0.19 |
-0.56 |
0.18 |
0.19 |
0.31 |
| Asian or Asian British |
-0.19 |
-0.62 |
0.25 |
0.22 |
0.40 |
| African or African British |
-0.65 |
-1.48 |
0.18 |
0.42 |
0.12 |
| Other ethnicity |
0.40 |
-0.27 |
1.07 |
0.34 |
0.24 |
| Time difference: Lockdown to baseline |
-0.22 |
-0.24 |
-0.19 |
0.01 |
2.91e-67 |
| Key worker |
0.19 |
0.06 |
0.31 |
0.06 |
0.003 |
| Retired |
-0.12 |
-0.30 |
0.06 |
0.09 |
0.20 |
| Student |
0.34 |
0.07 |
0.61 |
0.14 |
0.02 |
| Unemployed |
0.42 |
0.19 |
0.64 |
0.12 |
3.38e-04 |
| 30973 |
0.25 |
0.25 |
1678.24 |
0.00e+00 |
6 |
GAD prepan
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
3.00 |
2.20 |
3.80 |
0.41 |
1.91e-13 |
| gad.sum_score_prepan |
0.48 |
0.46 |
0.49 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
0.85 |
0.25 |
1.45 |
0.31 |
0.006 |
| Only depressive disorder |
-0.03 |
-0.68 |
0.62 |
0.33 |
0.93 |
| Only anxiety disorder |
0.08 |
-0.60 |
0.76 |
0.35 |
0.81 |
| Eating disorders |
0.70 |
0.40 |
1.00 |
0.15 |
5.34e-06 |
| OCDs |
0.53 |
0.25 |
0.81 |
0.14 |
2.40e-04 |
| Psychotic and bipolar disorder |
-0.17 |
-1.02 |
0.68 |
0.43 |
0.70 |
| Only psychotic disorder |
0.21 |
-0.48 |
0.90 |
0.35 |
0.55 |
| Only bipolar disorder |
0.24 |
-0.17 |
0.66 |
0.21 |
0.25 |
| PTSD |
0.78 |
0.51 |
1.04 |
0.14 |
1.73e-08 |
| ASD |
0.74 |
0.18 |
1.30 |
0.29 |
0.009 |
| ADHD |
-0.24 |
-1.01 |
0.52 |
0.39 |
0.53 |
| Personality disorder |
0.58 |
0.19 |
0.97 |
0.20 |
0.003 |
| Female |
0.40 |
0.15 |
0.64 |
0.13 |
0.002 |
| Non-binary/Self-defined |
0.44 |
-0.27 |
1.14 |
0.36 |
0.23 |
| age_category_collapsed_reordered16-18 |
1.08 |
0.49 |
1.67 |
0.30 |
3.64e-04 |
| age_category_collapsed_reordered19-25 |
0.79 |
0.46 |
1.11 |
0.17 |
1.91e-06 |
| age_category_collapsed_reordered36-45 |
-0.21 |
-0.49 |
0.07 |
0.14 |
0.15 |
| age_category_collapsed_reordered46-55 |
-0.56 |
-0.84 |
-0.28 |
0.14 |
7.33e-05 |
| age_category_collapsed_reordered56-65 |
-0.90 |
-1.25 |
-0.56 |
0.18 |
2.58e-07 |
| age_category_collapsed_reordered66-70 |
-1.67 |
-2.28 |
-1.05 |
0.31 |
1.11e-07 |
| age_category_collapsed_reordered71-75 |
-1.89 |
-2.67 |
-1.12 |
0.40 |
1.76e-06 |
| age_category_collapsed_reordered76+ |
-1.35 |
-2.73 |
0.02 |
0.70 |
0.05 |
| Mixed or multiple ethnic origins |
0.22 |
-0.42 |
0.85 |
0.32 |
0.51 |
| Asian or Asian British |
-0.12 |
-1.14 |
0.90 |
0.52 |
0.82 |
| African or African British |
-0.66 |
-2.35 |
1.03 |
0.86 |
0.45 |
| Other ethnicity |
0.39 |
-0.57 |
1.35 |
0.49 |
0.42 |
| Time difference: Lockdown to baseline |
0.00 |
-0.06 |
0.05 |
0.03 |
0.92 |
| Key worker |
0.15 |
-0.08 |
0.37 |
0.11 |
0.19 |
| Retired |
0.07 |
-0.35 |
0.49 |
0.21 |
0.75 |
| Student |
0.31 |
-0.14 |
0.76 |
0.23 |
0.17 |
| Unemployed |
0.98 |
0.63 |
1.34 |
0.18 |
4.59e-08 |
| 12028 |
0.00 |
0.00 |
8.99 |
7.92e-10 |
6 |
PHQ baseline
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
6.03 |
5.71 |
6.36 |
0.16 |
3.80e-286 |
| Depressive and anxiety disorder |
5.25 |
5.09 |
5.41 |
0.08 |
0.00e+00 |
| Only depressive disorder |
3.26 |
3.06 |
3.47 |
0.10 |
1.82e-209 |
| Only anxiety disorder |
1.97 |
1.71 |
2.23 |
0.13 |
1.12e-49 |
| Eating disorders |
1.55 |
1.28 |
1.82 |
0.14 |
1.81e-29 |
| OCDs |
1.29 |
1.03 |
1.55 |
0.13 |
2.57e-22 |
| Psychotic and bipolar disorder |
0.47 |
-0.28 |
1.23 |
0.38 |
0.22 |
| Only psychotic disorder |
0.48 |
-0.16 |
1.11 |
0.32 |
0.14 |
| Only bipolar disorder |
1.19 |
0.79 |
1.59 |
0.21 |
7.85e-09 |
| PTSD |
1.80 |
1.56 |
2.04 |
0.12 |
1.65e-47 |
| ASD |
1.25 |
0.77 |
1.72 |
0.24 |
3.09e-07 |
| ADHD |
1.20 |
0.57 |
1.82 |
0.32 |
1.73e-04 |
| Personality disorder |
2.42 |
2.06 |
2.78 |
0.18 |
2.21e-39 |
| Female |
0.86 |
0.71 |
1.01 |
0.08 |
1.39e-28 |
| Non-binary/Self-defined |
1.36 |
0.74 |
1.98 |
0.31 |
1.63e-05 |
| age_category_collapsed_reordered16-18 |
5.52 |
5.09 |
5.95 |
0.22 |
1.45e-139 |
| age_category_collapsed_reordered19-25 |
2.06 |
1.77 |
2.34 |
0.15 |
3.50e-45 |
| age_category_collapsed_reordered36-45 |
-0.78 |
-1.01 |
-0.54 |
0.12 |
1.41e-10 |
| age_category_collapsed_reordered46-55 |
-1.10 |
-1.32 |
-0.88 |
0.11 |
1.57e-22 |
| age_category_collapsed_reordered56-65 |
-1.94 |
-2.17 |
-1.71 |
0.12 |
2.52e-60 |
| age_category_collapsed_reordered66-70 |
-2.76 |
-3.08 |
-2.43 |
0.17 |
8.55e-62 |
| age_category_collapsed_reordered71-75 |
-2.93 |
-3.29 |
-2.57 |
0.19 |
9.47e-56 |
| age_category_collapsed_reordered76+ |
-2.78 |
-3.29 |
-2.28 |
0.26 |
3.86e-27 |
| Mixed or multiple ethnic origins |
0.43 |
-0.06 |
0.91 |
0.25 |
0.08 |
| Asian or Asian British |
0.24 |
-0.34 |
0.81 |
0.29 |
0.42 |
| African or African British |
-0.43 |
-1.51 |
0.66 |
0.55 |
0.44 |
| Other ethnicity |
1.02 |
0.16 |
1.88 |
0.44 |
0.02 |
| Time difference: Lockdown to baseline |
-0.23 |
-0.26 |
-0.20 |
0.02 |
5.19e-44 |
| Key worker |
0.03 |
-0.13 |
0.19 |
0.08 |
0.71 |
| Retired |
-0.04 |
-0.28 |
0.19 |
0.12 |
0.72 |
| Student |
1.07 |
0.71 |
1.43 |
0.18 |
6.60e-09 |
| Unemployed |
3.27 |
2.97 |
3.56 |
0.15 |
7.25e-104 |
| 32662 |
0.25 |
0.25 |
1854.75 |
0.00e+00 |
6 |
PHQ retro
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
4.10 |
3.84 |
4.37 |
0.14 |
4.96e-193 |
| phq.sum_score_retro |
0.68 |
0.66 |
0.69 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
2.68 |
2.53 |
2.83 |
0.07 |
3.84e-277 |
| Only depressive disorder |
1.69 |
1.52 |
1.86 |
0.09 |
2.24e-81 |
| Only anxiety disorder |
1.18 |
0.96 |
1.40 |
0.11 |
9.64e-27 |
| Eating disorders |
0.79 |
0.56 |
1.01 |
0.12 |
7.75e-12 |
| OCDs |
0.46 |
0.24 |
0.67 |
0.11 |
3.82e-05 |
| Psychotic and bipolar disorder |
0.02 |
-0.61 |
0.65 |
0.32 |
0.95 |
| Only psychotic disorder |
-0.05 |
-0.59 |
0.49 |
0.28 |
0.85 |
| Only bipolar disorder |
0.64 |
0.30 |
0.99 |
0.18 |
2.59e-04 |
| PTSD |
0.93 |
0.73 |
1.13 |
0.10 |
3.86e-19 |
| ASD |
0.55 |
0.15 |
0.95 |
0.20 |
0.007 |
| ADHD |
0.34 |
-0.19 |
0.86 |
0.27 |
0.21 |
| Personality disorder |
0.80 |
0.50 |
1.10 |
0.15 |
1.97e-07 |
| Female |
0.74 |
0.61 |
0.86 |
0.06 |
1.20e-30 |
| Non-binary/Self-defined |
0.54 |
0.03 |
1.05 |
0.26 |
0.04 |
| age_category_collapsed_reordered16-18 |
2.82 |
2.46 |
3.17 |
0.18 |
5.88e-55 |
| age_category_collapsed_reordered19-25 |
1.20 |
0.96 |
1.43 |
0.12 |
1.97e-23 |
| age_category_collapsed_reordered36-45 |
-0.59 |
-0.79 |
-0.40 |
0.10 |
3.85e-09 |
| age_category_collapsed_reordered46-55 |
-0.77 |
-0.95 |
-0.59 |
0.09 |
1.94e-16 |
| age_category_collapsed_reordered56-65 |
-1.16 |
-1.35 |
-0.97 |
0.10 |
3.13e-32 |
| age_category_collapsed_reordered66-70 |
-1.59 |
-1.86 |
-1.32 |
0.14 |
6.05e-31 |
| age_category_collapsed_reordered71-75 |
-1.75 |
-2.05 |
-1.45 |
0.15 |
7.25e-30 |
| age_category_collapsed_reordered76+ |
-1.77 |
-2.19 |
-1.35 |
0.21 |
1.04e-16 |
| Mixed or multiple ethnic origins |
0.12 |
-0.28 |
0.52 |
0.20 |
0.55 |
| Asian or Asian British |
0.00 |
-0.47 |
0.47 |
0.24 |
1.00 |
| African or African British |
-0.43 |
-1.32 |
0.46 |
0.46 |
0.34 |
| Other ethnicity |
0.48 |
-0.24 |
1.20 |
0.37 |
0.19 |
| Time difference: Lockdown to baseline |
-0.22 |
-0.25 |
-0.19 |
0.01 |
4.59e-58 |
| Key worker |
0.11 |
-0.02 |
0.24 |
0.07 |
0.10 |
| Retired |
-0.19 |
-0.39 |
0.00 |
0.10 |
0.06 |
| Student |
0.44 |
0.15 |
0.74 |
0.15 |
0.003 |
| Unemployed |
0.65 |
0.40 |
0.90 |
0.13 |
2.92e-07 |
| 30959 |
0.28 |
0.28 |
2029.98 |
0.00e+00 |
6 |
PHQ prepan
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.51 |
1.66 |
3.37 |
0.44 |
7.90e-09 |
| phq.sum_score_prepan |
0.54 |
0.53 |
0.56 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
1.25 |
0.61 |
1.90 |
0.33 |
1.29e-04 |
| Only depressive disorder |
0.80 |
0.11 |
1.49 |
0.35 |
0.02 |
| Only anxiety disorder |
0.20 |
-0.53 |
0.92 |
0.37 |
0.59 |
| Eating disorders |
0.95 |
0.63 |
1.27 |
0.16 |
8.00e-09 |
| OCDs |
0.51 |
0.21 |
0.82 |
0.15 |
7.98e-04 |
| Psychotic and bipolar disorder |
-0.82 |
-1.73 |
0.09 |
0.46 |
0.08 |
| Only psychotic disorder |
0.14 |
-0.59 |
0.88 |
0.38 |
0.70 |
| Only bipolar disorder |
0.27 |
-0.17 |
0.72 |
0.23 |
0.23 |
| PTSD |
0.57 |
0.28 |
0.86 |
0.15 |
9.92e-05 |
| ASD |
0.66 |
0.06 |
1.25 |
0.30 |
0.03 |
| ADHD |
0.35 |
-0.47 |
1.16 |
0.42 |
0.41 |
| Personality disorder |
0.90 |
0.49 |
1.31 |
0.21 |
1.73e-05 |
| Female |
0.15 |
-0.12 |
0.41 |
0.13 |
0.28 |
| Non-binary/Self-defined |
0.28 |
-0.48 |
1.03 |
0.38 |
0.47 |
| age_category_collapsed_reordered16-18 |
1.92 |
1.28 |
2.55 |
0.32 |
3.07e-09 |
| age_category_collapsed_reordered19-25 |
0.88 |
0.54 |
1.23 |
0.18 |
5.57e-07 |
| age_category_collapsed_reordered36-45 |
-0.26 |
-0.56 |
0.05 |
0.15 |
0.10 |
| age_category_collapsed_reordered46-55 |
-0.54 |
-0.83 |
-0.24 |
0.15 |
3.83e-04 |
| age_category_collapsed_reordered56-65 |
-1.03 |
-1.39 |
-0.66 |
0.19 |
3.50e-08 |
| age_category_collapsed_reordered66-70 |
-1.82 |
-2.47 |
-1.17 |
0.33 |
4.80e-08 |
| age_category_collapsed_reordered71-75 |
-2.31 |
-3.14 |
-1.48 |
0.42 |
4.64e-08 |
| age_category_collapsed_reordered76+ |
-1.71 |
-3.18 |
-0.23 |
0.75 |
0.02 |
| Mixed or multiple ethnic origins |
0.25 |
-0.43 |
0.92 |
0.34 |
0.48 |
| Asian or Asian British |
-0.70 |
-1.78 |
0.38 |
0.55 |
0.20 |
| African or African British |
-0.20 |
-1.99 |
1.60 |
0.92 |
0.83 |
| Other ethnicity |
0.16 |
-0.87 |
1.19 |
0.53 |
0.76 |
| Time difference: Lockdown to baseline |
0.08 |
0.01 |
0.14 |
0.03 |
0.01 |
| Key worker |
0.06 |
-0.18 |
0.29 |
0.12 |
0.64 |
| Retired |
0.40 |
-0.05 |
0.84 |
0.23 |
0.08 |
| Student |
0.55 |
0.07 |
1.02 |
0.24 |
0.02 |
| Unemployed |
1.42 |
1.05 |
1.80 |
0.19 |
1.81e-13 |
| 12024 |
0.02 |
0.02 |
41.62 |
1.65e-50 |
6 |
OCIR baseline
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
15.55 |
13.93 |
17.18 |
0.83 |
1.41e-75 |
| Depressive and anxiety disorder |
3.06 |
2.16 |
3.96 |
0.46 |
2.95e-11 |
| Only depressive disorder |
0.39 |
-0.81 |
1.60 |
0.62 |
0.52 |
| Only anxiety disorder |
1.00 |
-0.23 |
2.22 |
0.62 |
0.11 |
| Eating disorders |
0.59 |
-0.52 |
1.69 |
0.56 |
0.30 |
| OCDs |
6.39 |
5.42 |
7.36 |
0.49 |
1.78e-37 |
| Psychotic and bipolar disorder |
6.53 |
3.92 |
9.14 |
1.33 |
9.80e-07 |
| Only psychotic disorder |
3.52 |
1.06 |
5.98 |
1.26 |
0.005 |
| Only bipolar disorder |
2.98 |
1.24 |
4.73 |
0.89 |
7.81e-04 |
| PTSD |
1.99 |
1.01 |
2.97 |
0.50 |
6.59e-05 |
| ASD |
7.23 |
5.45 |
9.00 |
0.91 |
2.01e-15 |
| ADHD |
2.14 |
-0.25 |
4.53 |
1.22 |
0.08 |
| Personality disorder |
2.70 |
1.30 |
4.11 |
0.72 |
1.65e-04 |
| Female |
-1.11 |
-2.03 |
-0.19 |
0.47 |
0.02 |
| Non-binary/Self-defined |
-0.89 |
-3.43 |
1.65 |
1.30 |
0.49 |
| age_category_collapsed_reordered16-18 |
8.54 |
6.87 |
10.21 |
0.85 |
2.00e-23 |
| age_category_collapsed_reordered19-25 |
1.93 |
0.67 |
3.18 |
0.64 |
0.003 |
| age_category_collapsed_reordered36-45 |
-0.42 |
-1.61 |
0.77 |
0.61 |
0.49 |
| age_category_collapsed_reordered46-55 |
-0.25 |
-1.35 |
0.86 |
0.56 |
0.66 |
| age_category_collapsed_reordered56-65 |
-0.62 |
-1.79 |
0.55 |
0.60 |
0.30 |
| age_category_collapsed_reordered66-70 |
0.28 |
-1.56 |
2.12 |
0.94 |
0.77 |
| age_category_collapsed_reordered71-75 |
-0.79 |
-2.93 |
1.35 |
1.09 |
0.47 |
| age_category_collapsed_reordered76+ |
-2.52 |
-6.10 |
1.06 |
1.83 |
0.17 |
| Mixed or multiple ethnic origins |
0.88 |
-1.33 |
3.09 |
1.13 |
0.43 |
| Asian or Asian British |
5.32 |
2.47 |
8.17 |
1.45 |
2.50e-04 |
| African or African British |
-0.45 |
-7.25 |
6.36 |
3.47 |
0.90 |
| Other ethnicity |
3.05 |
-0.25 |
6.34 |
1.68 |
0.07 |
| Time difference: Lockdown to baseline |
-0.44 |
-0.60 |
-0.29 |
0.08 |
2.72e-08 |
| Key worker |
0.02 |
-0.81 |
0.85 |
0.42 |
0.96 |
| Retired |
-0.45 |
-1.76 |
0.86 |
0.67 |
0.50 |
| Student |
-0.09 |
-1.60 |
1.42 |
0.77 |
0.90 |
| Unemployed |
3.73 |
2.46 |
5.00 |
0.65 |
8.65e-09 |
| 5506 |
0.05 |
0.05 |
52.82 |
1.41e-63 |
6 |
OCIR retro
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
12.95 |
11.63 |
14.27 |
0.67 |
3.15e-79 |
| ocir.sum_score_retro |
0.74 |
0.71 |
0.76 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
-1.13 |
-1.87 |
-0.39 |
0.38 |
0.003 |
| Only depressive disorder |
-0.96 |
-1.95 |
0.03 |
0.51 |
0.06 |
| Only anxiety disorder |
-0.18 |
-1.18 |
0.83 |
0.51 |
0.73 |
| Eating disorders |
0.05 |
-0.83 |
0.92 |
0.45 |
0.92 |
| OCDs |
1.93 |
1.16 |
2.70 |
0.39 |
9.08e-07 |
| Psychotic and bipolar disorder |
3.06 |
1.04 |
5.09 |
1.03 |
0.003 |
| Only psychotic disorder |
0.73 |
-1.17 |
2.63 |
0.97 |
0.45 |
| Only bipolar disorder |
0.41 |
-0.89 |
1.72 |
0.67 |
0.54 |
| PTSD |
0.49 |
-0.27 |
1.25 |
0.39 |
0.21 |
| ASD |
2.41 |
0.99 |
3.83 |
0.72 |
8.79e-04 |
| ADHD |
1.92 |
-0.04 |
3.88 |
1.00 |
0.05 |
| Personality disorder |
0.60 |
-0.48 |
1.68 |
0.55 |
0.28 |
| Female |
-0.02 |
-0.75 |
0.71 |
0.37 |
0.96 |
| Non-binary/Self-defined |
-0.31 |
-2.32 |
1.71 |
1.03 |
0.77 |
| age_category_collapsed_reordered16-18 |
5.16 |
3.75 |
6.58 |
0.72 |
1.09e-12 |
| age_category_collapsed_reordered19-25 |
0.15 |
-0.84 |
1.14 |
0.50 |
0.77 |
| age_category_collapsed_reordered36-45 |
-0.26 |
-1.17 |
0.66 |
0.47 |
0.58 |
| age_category_collapsed_reordered46-55 |
-0.01 |
-0.86 |
0.85 |
0.44 |
0.99 |
| age_category_collapsed_reordered56-65 |
1.20 |
0.28 |
2.12 |
0.47 |
0.01 |
| age_category_collapsed_reordered66-70 |
1.91 |
0.45 |
3.38 |
0.75 |
0.01 |
| age_category_collapsed_reordered71-75 |
1.57 |
-0.16 |
3.30 |
0.88 |
0.08 |
| age_category_collapsed_reordered76+ |
-0.49 |
-3.72 |
2.74 |
1.65 |
0.76 |
| Mixed or multiple ethnic origins |
1.09 |
-0.64 |
2.81 |
0.88 |
0.22 |
| Asian or Asian British |
3.72 |
1.25 |
6.19 |
1.26 |
0.003 |
| African or African British |
-0.78 |
-6.52 |
4.95 |
2.93 |
0.79 |
| Other ethnicity |
1.56 |
-0.95 |
4.07 |
1.28 |
0.22 |
| Time difference: Lockdown to baseline |
-1.36 |
-1.48 |
-1.23 |
0.06 |
1.07e-95 |
| Key worker |
-0.09 |
-0.74 |
0.56 |
0.33 |
0.78 |
| Retired |
-0.33 |
-1.37 |
0.71 |
0.53 |
0.54 |
| Student |
-0.26 |
-1.50 |
0.99 |
0.63 |
0.69 |
| Unemployed |
1.38 |
0.38 |
2.38 |
0.51 |
0.007 |
| 5455 |
0.06 |
0.05 |
53.30 |
3.86e-64 |
6 |
OCIR prepan
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
3.39 |
-6.55 |
13.33 |
5.05 |
0.50 |
| ocir.sum_score_prepan |
0.65 |
0.57 |
0.73 |
0.04 |
2.08e-45 |
| Depressive and anxiety disorder |
-4.41 |
-12.18 |
3.36 |
3.95 |
0.27 |
| Only depressive disorder |
-5.27 |
-13.66 |
3.12 |
4.27 |
0.22 |
| Only anxiety disorder |
-7.72 |
-16.17 |
0.72 |
4.29 |
0.07 |
| Eating disorders |
0.96 |
-1.62 |
3.54 |
1.31 |
0.47 |
| OCDs |
1.44 |
-0.82 |
3.70 |
1.15 |
0.21 |
| Psychotic and bipolar disorder |
10.01 |
2.01 |
18.01 |
4.07 |
0.01 |
| Only psychotic disorder |
-0.38 |
-6.01 |
5.24 |
2.86 |
0.89 |
| Only bipolar disorder |
-0.93 |
-4.56 |
2.70 |
1.85 |
0.61 |
| PTSD |
-2.55 |
-5.07 |
-0.03 |
1.28 |
0.05 |
| ASD |
1.02 |
-3.21 |
5.24 |
2.15 |
0.64 |
| ADHD |
0.68 |
-6.22 |
7.58 |
3.51 |
0.85 |
| Personality disorder |
0.61 |
-2.59 |
3.81 |
1.63 |
0.71 |
| Female |
-1.97 |
-4.98 |
1.05 |
1.53 |
0.20 |
| Non-binary/Self-defined |
-1.14 |
-7.03 |
4.75 |
3.00 |
0.70 |
| age_category_collapsed_reordered16-18 |
-4.50 |
-10.66 |
1.66 |
3.13 |
0.15 |
| age_category_collapsed_reordered19-25 |
-0.92 |
-3.76 |
1.93 |
1.45 |
0.53 |
| age_category_collapsed_reordered36-45 |
-0.64 |
-3.51 |
2.24 |
1.46 |
0.66 |
| age_category_collapsed_reordered46-55 |
2.11 |
-0.86 |
5.08 |
1.51 |
0.16 |
| age_category_collapsed_reordered56-65 |
-4.28 |
-8.53 |
-0.03 |
2.16 |
0.05 |
| age_category_collapsed_reordered66-70 |
-3.86 |
-10.56 |
2.85 |
3.41 |
0.26 |
| age_category_collapsed_reordered71-75 |
-2.79 |
-12.84 |
7.25 |
5.11 |
0.58 |
| Mixed or multiple ethnic origins |
-0.24 |
-6.52 |
6.04 |
3.19 |
0.94 |
| Asian or Asian British |
-13.18 |
-26.48 |
0.12 |
6.76 |
0.05 |
| Other ethnicity |
2.26 |
-5.39 |
9.92 |
3.89 |
0.56 |
| Time difference: Lockdown to baseline |
0.62 |
-0.10 |
1.33 |
0.36 |
0.09 |
| Key worker |
0.22 |
-2.12 |
2.55 |
1.19 |
0.85 |
| Retired |
3.55 |
-1.14 |
8.24 |
2.39 |
0.14 |
| Student |
-1.57 |
-5.36 |
2.23 |
1.93 |
0.42 |
| Unemployed |
0.70 |
-2.46 |
3.86 |
1.61 |
0.66 |
| 1873 |
0.03 |
0.03 |
9.40 |
3.43e-10 |
6 |
PCL baseline
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
9.77 |
9.49 |
10.05 |
0.14 |
0.00e+00 |
| Depressive and anxiety disorder |
5.00 |
4.86 |
5.15 |
0.07 |
0.00e+00 |
| Only depressive disorder |
2.58 |
2.40 |
2.76 |
0.09 |
4.64e-171 |
| Only anxiety disorder |
2.40 |
2.17 |
2.62 |
0.12 |
9.15e-94 |
| Eating disorders |
0.82 |
0.58 |
1.06 |
0.12 |
9.75e-12 |
| OCDs |
1.19 |
0.97 |
1.42 |
0.12 |
9.47e-25 |
| Psychotic and bipolar disorder |
1.50 |
0.84 |
2.15 |
0.34 |
8.22e-06 |
| Only psychotic disorder |
0.43 |
-0.13 |
0.98 |
0.28 |
0.13 |
| Only bipolar disorder |
0.98 |
0.62 |
1.33 |
0.18 |
6.63e-08 |
| PTSD |
2.69 |
2.48 |
2.91 |
0.11 |
4.58e-134 |
| ASD |
1.05 |
0.63 |
1.47 |
0.21 |
8.16e-07 |
| ADHD |
0.68 |
0.13 |
1.24 |
0.28 |
0.02 |
| Personality disorder |
2.14 |
1.82 |
2.45 |
0.16 |
4.91e-40 |
| Female |
0.71 |
0.58 |
0.84 |
0.07 |
1.25e-25 |
| Non-binary/Self-defined |
1.22 |
0.68 |
1.76 |
0.28 |
9.71e-06 |
| age_category_collapsed_reordered16-18 |
3.44 |
3.07 |
3.82 |
0.19 |
4.21e-72 |
| age_category_collapsed_reordered19-25 |
1.65 |
1.40 |
1.90 |
0.13 |
6.06e-38 |
| age_category_collapsed_reordered36-45 |
-0.70 |
-0.91 |
-0.50 |
0.11 |
3.53e-11 |
| age_category_collapsed_reordered46-55 |
-1.04 |
-1.23 |
-0.85 |
0.10 |
4.69e-26 |
| age_category_collapsed_reordered56-65 |
-1.63 |
-1.83 |
-1.42 |
0.10 |
3.02e-55 |
| age_category_collapsed_reordered66-70 |
-2.03 |
-2.31 |
-1.74 |
0.15 |
3.74e-44 |
| age_category_collapsed_reordered71-75 |
-2.20 |
-2.52 |
-1.88 |
0.16 |
1.50e-41 |
| age_category_collapsed_reordered76+ |
-2.02 |
-2.46 |
-1.57 |
0.23 |
4.54e-19 |
| Mixed or multiple ethnic origins |
0.53 |
0.10 |
0.95 |
0.22 |
0.02 |
| Asian or Asian British |
0.69 |
0.18 |
1.19 |
0.26 |
0.007 |
| African or African British |
0.56 |
-0.39 |
1.51 |
0.48 |
0.25 |
| Other ethnicity |
0.79 |
0.04 |
1.54 |
0.38 |
0.04 |
| Time difference: Lockdown to baseline |
-0.03 |
-0.06 |
-0.01 |
0.01 |
0.02 |
| Key worker |
-0.08 |
-0.22 |
0.06 |
0.07 |
0.26 |
| Retired |
-0.13 |
-0.34 |
0.08 |
0.11 |
0.22 |
| Student |
0.72 |
0.40 |
1.03 |
0.16 |
9.01e-06 |
| Unemployed |
2.37 |
2.11 |
2.63 |
0.13 |
5.98e-72 |
| 32567 |
0.27 |
0.27 |
1987.28 |
0.00e+00 |
6 |
#PCL prepan ### Model 1b: Overlapping disorders, Adjusted Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
6.29 |
5.43 |
7.15 |
0.44 |
3.13e-46 |
| pcl.sum_score_prepan |
0.50 |
0.48 |
0.52 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
0.64 |
0.01 |
1.27 |
0.32 |
0.05 |
| Only depressive disorder |
-0.13 |
-0.82 |
0.55 |
0.35 |
0.70 |
| Only anxiety disorder |
-0.65 |
-1.36 |
0.07 |
0.36 |
0.08 |
| Eating disorders |
0.43 |
0.11 |
0.75 |
0.16 |
0.008 |
| OCDs |
0.46 |
0.16 |
0.76 |
0.15 |
0.002 |
| Psychotic and bipolar disorder |
-0.23 |
-1.12 |
0.65 |
0.45 |
0.61 |
| Only psychotic disorder |
-0.13 |
-0.86 |
0.60 |
0.37 |
0.73 |
| Only bipolar disorder |
0.44 |
0.00 |
0.88 |
0.23 |
0.05 |
| PTSD |
0.80 |
0.51 |
1.09 |
0.15 |
5.26e-08 |
| ASD |
0.45 |
-0.14 |
1.04 |
0.30 |
0.14 |
| ADHD |
0.34 |
-0.48 |
1.16 |
0.42 |
0.41 |
| Personality disorder |
0.65 |
0.25 |
1.06 |
0.21 |
0.002 |
| Female |
0.52 |
0.25 |
0.78 |
0.13 |
1.05e-04 |
| Non-binary/Self-defined |
0.52 |
-0.22 |
1.27 |
0.38 |
0.17 |
| age_category_collapsed_reordered16-18 |
1.15 |
0.52 |
1.77 |
0.32 |
3.18e-04 |
| age_category_collapsed_reordered19-25 |
0.87 |
0.53 |
1.21 |
0.17 |
6.28e-07 |
| age_category_collapsed_reordered36-45 |
-0.59 |
-0.89 |
-0.29 |
0.15 |
1.07e-04 |
| age_category_collapsed_reordered46-55 |
-0.71 |
-1.00 |
-0.41 |
0.15 |
2.25e-06 |
| age_category_collapsed_reordered56-65 |
-0.83 |
-1.19 |
-0.47 |
0.18 |
6.52e-06 |
| age_category_collapsed_reordered66-70 |
-1.59 |
-2.24 |
-0.95 |
0.33 |
1.33e-06 |
| age_category_collapsed_reordered71-75 |
-1.94 |
-2.76 |
-1.12 |
0.42 |
3.66e-06 |
| age_category_collapsed_reordered76+ |
-1.53 |
-2.98 |
-0.07 |
0.74 |
0.04 |
| Mixed or multiple ethnic origins |
0.35 |
-0.31 |
1.02 |
0.34 |
0.30 |
| Asian or Asian British |
0.53 |
-0.55 |
1.62 |
0.55 |
0.33 |
| African or African British |
0.37 |
-1.39 |
2.14 |
0.90 |
0.68 |
| Other ethnicity |
0.19 |
-0.82 |
1.21 |
0.52 |
0.71 |
| Time difference: Lockdown to baseline |
0.10 |
0.04 |
0.16 |
0.03 |
7.03e-04 |
| Key worker |
-0.25 |
-0.48 |
-0.01 |
0.12 |
0.04 |
| Retired |
-0.03 |
-0.47 |
0.41 |
0.22 |
0.88 |
| Student |
0.27 |
-0.20 |
0.74 |
0.24 |
0.26 |
| Unemployed |
1.21 |
0.83 |
1.58 |
0.19 |
2.20e-10 |
| 11940 |
0.01 |
0.01 |
30.02 |
6.05e-36 |
6 |
Sensitivity anlayses based on employment change
Function change to include employment change as predictors
GAD baseline
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
9.24 |
8.63 |
9.85 |
0.31 |
1.13e-188 |
| Depressive and anxiety disorder |
4.77 |
4.59 |
4.96 |
0.09 |
0.00e+00 |
| Only depressive disorder |
1.98 |
1.74 |
2.22 |
0.12 |
3.94e-57 |
| Only anxiety disorder |
3.28 |
2.98 |
3.58 |
0.15 |
1.87e-100 |
| Eating disorders |
0.69 |
0.40 |
0.97 |
0.14 |
1.94e-06 |
| OCDs |
1.36 |
1.09 |
1.62 |
0.14 |
3.65e-23 |
| Psychotic and bipolar disorder |
0.59 |
-0.17 |
1.35 |
0.39 |
0.13 |
| Only psychotic disorder |
0.24 |
-0.42 |
0.91 |
0.34 |
0.47 |
| Only bipolar disorder |
0.71 |
0.30 |
1.12 |
0.21 |
6.25e-04 |
| PTSD |
1.47 |
1.22 |
1.72 |
0.13 |
1.10e-30 |
| ASD |
1.05 |
0.55 |
1.55 |
0.25 |
3.70e-05 |
| ADHD |
0.41 |
-0.23 |
1.05 |
0.33 |
0.21 |
| Personality disorder |
1.96 |
1.61 |
2.31 |
0.18 |
3.92e-28 |
| Female |
0.98 |
0.80 |
1.15 |
0.09 |
6.41e-27 |
| Non-binary/Self-defined |
0.78 |
0.10 |
1.46 |
0.35 |
0.02 |
| 19-25 years |
-2.04 |
-2.61 |
-1.47 |
0.29 |
2.25e-12 |
| 26-35 years |
-3.53 |
-4.07 |
-2.99 |
0.27 |
8.94e-38 |
| 36-45 years |
-4.19 |
-4.73 |
-3.65 |
0.28 |
8.73e-52 |
| 46-55 years |
-4.65 |
-5.19 |
-4.12 |
0.27 |
9.12e-65 |
| 56-65 years |
-5.22 |
-5.77 |
-4.68 |
0.28 |
2.70e-79 |
| 66-70 years |
-6.53 |
-7.22 |
-5.84 |
0.35 |
8.47e-76 |
| 71-75 years |
-6.03 |
-6.88 |
-5.18 |
0.43 |
9.89e-44 |
| 76+ years |
-5.29 |
-6.68 |
-3.90 |
0.71 |
8.82e-14 |
| Mixed or multiple ethnic origins |
0.00 |
-0.52 |
0.52 |
0.26 |
0.99 |
| Asian or Asian British |
0.24 |
-0.42 |
0.89 |
0.34 |
0.48 |
| African or African British |
-0.34 |
-1.45 |
0.77 |
0.57 |
0.54 |
| Other ethnicity |
0.53 |
-0.41 |
1.48 |
0.48 |
0.27 |
| Key worker |
-0.50 |
-0.64 |
-0.35 |
0.08 |
3.95e-11 |
| Time difference: Lockdown to baseline |
-0.24 |
-0.28 |
-0.21 |
0.02 |
1.10e-41 |
| Increased employment |
0.31 |
-0.06 |
0.68 |
0.19 |
0.10 |
| Furloughed |
-0.32 |
-0.59 |
-0.05 |
0.14 |
0.02 |
| employment_changeEmployment not changed |
-0.33 |
-0.53 |
-0.12 |
0.11 |
0.002 |
GAD retro
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
3.64 |
3.39 |
3.88 |
0.13 |
5.83e-177 |
| gad.sum_score_retro |
0.66 |
0.65 |
0.67 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
2.41 |
2.27 |
2.54 |
0.07 |
2.00e-262 |
| Only depressive disorder |
1.02 |
0.86 |
1.18 |
0.08 |
1.50e-36 |
| Only anxiety disorder |
1.76 |
1.56 |
1.97 |
0.10 |
4.85e-66 |
| Eating disorders |
0.55 |
0.34 |
0.76 |
0.11 |
2.52e-07 |
| OCDs |
0.47 |
0.27 |
0.68 |
0.10 |
4.01e-06 |
| Psychotic and bipolar disorder |
0.72 |
0.14 |
1.30 |
0.30 |
0.02 |
| Only psychotic disorder |
0.00 |
-0.50 |
0.50 |
0.25 |
1.00 |
| Only bipolar disorder |
0.32 |
0.00 |
0.64 |
0.16 |
0.05 |
| PTSD |
0.77 |
0.58 |
0.96 |
0.10 |
1.49e-15 |
| ASD |
0.65 |
0.28 |
1.02 |
0.19 |
5.64e-04 |
| ADHD |
0.10 |
-0.39 |
0.58 |
0.25 |
0.70 |
| Personality disorder |
0.44 |
0.17 |
0.72 |
0.14 |
0.002 |
| Female |
0.78 |
0.66 |
0.89 |
0.06 |
3.12e-39 |
| Non-binary/Self-defined |
0.13 |
-0.34 |
0.60 |
0.24 |
0.59 |
| age_category_collapsed_reordered16-18 |
0.89 |
0.56 |
1.21 |
0.17 |
9.99e-08 |
| age_category_collapsed_reordered19-25 |
0.89 |
0.67 |
1.11 |
0.11 |
1.03e-15 |
| age_category_collapsed_reordered36-45 |
-0.57 |
-0.75 |
-0.39 |
0.09 |
9.59e-10 |
| age_category_collapsed_reordered46-55 |
-0.87 |
-1.04 |
-0.70 |
0.09 |
1.10e-23 |
| age_category_collapsed_reordered56-65 |
-1.19 |
-1.37 |
-1.01 |
0.09 |
3.65e-39 |
| age_category_collapsed_reordered66-70 |
-1.58 |
-1.83 |
-1.33 |
0.13 |
2.29e-35 |
| age_category_collapsed_reordered71-75 |
-1.78 |
-2.06 |
-1.50 |
0.14 |
9.33e-36 |
| age_category_collapsed_reordered76+ |
-1.82 |
-2.20 |
-1.43 |
0.20 |
2.57e-20 |
| Mixed or multiple ethnic origins |
-0.19 |
-0.56 |
0.18 |
0.19 |
0.31 |
| Asian or Asian British |
-0.19 |
-0.62 |
0.25 |
0.22 |
0.40 |
| African or African British |
-0.65 |
-1.48 |
0.18 |
0.42 |
0.12 |
| Other ethnicity |
0.40 |
-0.27 |
1.07 |
0.34 |
0.24 |
| Key worker |
0.19 |
0.06 |
0.31 |
0.06 |
0.003 |
| Retired |
-0.12 |
-0.30 |
0.06 |
0.09 |
0.20 |
| Student |
0.34 |
0.07 |
0.61 |
0.14 |
0.02 |
| Unemployed |
0.42 |
0.19 |
0.64 |
0.12 |
3.38e-04 |
| Time difference: Lockdown to baseline |
-0.22 |
-0.24 |
-0.19 |
0.01 |
2.91e-67 |
GAD prepan
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
3.00 |
2.20 |
3.80 |
0.41 |
1.91e-13 |
| gad.sum_score_prepan |
0.48 |
0.46 |
0.49 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
0.85 |
0.25 |
1.45 |
0.31 |
0.006 |
| Only depressive disorder |
-0.03 |
-0.68 |
0.62 |
0.33 |
0.93 |
| Only anxiety disorder |
0.08 |
-0.60 |
0.76 |
0.35 |
0.81 |
| Eating disorders |
0.70 |
0.40 |
1.00 |
0.15 |
5.34e-06 |
| OCDs |
0.53 |
0.25 |
0.81 |
0.14 |
2.40e-04 |
| Psychotic and bipolar disorder |
-0.17 |
-1.02 |
0.68 |
0.43 |
0.70 |
| Only psychotic disorder |
0.21 |
-0.48 |
0.90 |
0.35 |
0.55 |
| Only bipolar disorder |
0.24 |
-0.17 |
0.66 |
0.21 |
0.25 |
| PTSD |
0.78 |
0.51 |
1.04 |
0.14 |
1.73e-08 |
| ASD |
0.74 |
0.18 |
1.30 |
0.29 |
0.009 |
| ADHD |
-0.24 |
-1.01 |
0.52 |
0.39 |
0.53 |
| Personality disorder |
0.58 |
0.19 |
0.97 |
0.20 |
0.003 |
| Female |
0.40 |
0.15 |
0.64 |
0.13 |
0.002 |
| Non-binary/Self-defined |
0.44 |
-0.27 |
1.14 |
0.36 |
0.23 |
| age_category_collapsed_reordered16-18 |
1.08 |
0.49 |
1.67 |
0.30 |
3.64e-04 |
| age_category_collapsed_reordered19-25 |
0.79 |
0.46 |
1.11 |
0.17 |
1.91e-06 |
| age_category_collapsed_reordered36-45 |
-0.21 |
-0.49 |
0.07 |
0.14 |
0.15 |
| age_category_collapsed_reordered46-55 |
-0.56 |
-0.84 |
-0.28 |
0.14 |
7.33e-05 |
| age_category_collapsed_reordered56-65 |
-0.90 |
-1.25 |
-0.56 |
0.18 |
2.58e-07 |
| age_category_collapsed_reordered66-70 |
-1.67 |
-2.28 |
-1.05 |
0.31 |
1.11e-07 |
| age_category_collapsed_reordered71-75 |
-1.89 |
-2.67 |
-1.12 |
0.40 |
1.76e-06 |
| age_category_collapsed_reordered76+ |
-1.35 |
-2.73 |
0.02 |
0.70 |
0.05 |
| Mixed or multiple ethnic origins |
0.22 |
-0.42 |
0.85 |
0.32 |
0.51 |
| Asian or Asian British |
-0.12 |
-1.14 |
0.90 |
0.52 |
0.82 |
| African or African British |
-0.66 |
-2.35 |
1.03 |
0.86 |
0.45 |
| Other ethnicity |
0.39 |
-0.57 |
1.35 |
0.49 |
0.42 |
| Key worker |
0.15 |
-0.08 |
0.37 |
0.11 |
0.19 |
| Retired |
0.07 |
-0.35 |
0.49 |
0.21 |
0.75 |
| Student |
0.31 |
-0.14 |
0.76 |
0.23 |
0.17 |
| Unemployed |
0.98 |
0.63 |
1.34 |
0.18 |
4.59e-08 |
| Time difference: Lockdown to baseline |
0.00 |
-0.06 |
0.05 |
0.03 |
0.92 |
GAD retro GLAD and EDGI sensitivity
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
3.72 |
2.96 |
4.48 |
0.39 |
1.26e-21 |
| gad.sum_score_retro |
0.63 |
0.61 |
0.65 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
0.88 |
0.30 |
1.46 |
0.29 |
0.003 |
| Only depressive disorder |
-0.14 |
-0.76 |
0.48 |
0.32 |
0.66 |
| Only anxiety disorder |
0.58 |
-0.07 |
1.23 |
0.33 |
0.08 |
| Eating disorders |
0.66 |
0.37 |
0.95 |
0.15 |
8.31e-06 |
| OCDs |
0.41 |
0.14 |
0.69 |
0.14 |
0.003 |
| Psychotic and bipolar disorder |
0.31 |
-0.50 |
1.13 |
0.42 |
0.45 |
| Only psychotic disorder |
-0.17 |
-0.84 |
0.50 |
0.34 |
0.62 |
| Only bipolar disorder |
0.08 |
-0.32 |
0.49 |
0.21 |
0.69 |
| PTSD |
0.81 |
0.55 |
1.07 |
0.13 |
9.02e-10 |
| ASD |
0.59 |
0.06 |
1.13 |
0.28 |
0.03 |
| ADHD |
0.12 |
-0.62 |
0.86 |
0.38 |
0.74 |
| Personality disorder |
0.52 |
0.15 |
0.89 |
0.19 |
0.006 |
| Female |
0.50 |
0.26 |
0.73 |
0.12 |
4.23e-05 |
| Non-binary/Self-defined |
-0.13 |
-0.81 |
0.56 |
0.35 |
0.71 |
| age_category_collapsed_reordered16-18 |
0.71 |
0.14 |
1.28 |
0.29 |
0.02 |
| age_category_collapsed_reordered19-25 |
0.91 |
0.59 |
1.22 |
0.16 |
1.34e-08 |
| age_category_collapsed_reordered36-45 |
-0.48 |
-0.75 |
-0.21 |
0.14 |
5.18e-04 |
| age_category_collapsed_reordered46-55 |
-0.80 |
-1.07 |
-0.54 |
0.14 |
4.04e-09 |
| age_category_collapsed_reordered56-65 |
-1.28 |
-1.61 |
-0.95 |
0.17 |
3.18e-14 |
| age_category_collapsed_reordered66-70 |
-1.80 |
-2.39 |
-1.21 |
0.30 |
2.39e-09 |
| age_category_collapsed_reordered71-75 |
-2.11 |
-2.86 |
-1.37 |
0.38 |
2.91e-08 |
| age_category_collapsed_reordered76+ |
-2.36 |
-3.69 |
-1.02 |
0.68 |
5.40e-04 |
| Mixed or multiple ethnic origins |
-0.28 |
-0.88 |
0.33 |
0.31 |
0.37 |
| Asian or Asian British |
0.10 |
-0.88 |
1.08 |
0.50 |
0.84 |
| African or African British |
-0.61 |
-2.24 |
1.02 |
0.83 |
0.46 |
| Other ethnicity |
0.25 |
-0.68 |
1.18 |
0.48 |
0.60 |
| Key worker |
0.25 |
0.03 |
0.46 |
0.11 |
0.02 |
| Retired |
-0.03 |
-0.43 |
0.37 |
0.21 |
0.89 |
| Student |
0.52 |
0.09 |
0.95 |
0.22 |
0.02 |
| Unemployed |
0.67 |
0.33 |
1.01 |
0.17 |
1.18e-04 |
| Time difference: Lockdown to baseline |
-0.04 |
-0.09 |
0.02 |
0.03 |
0.17 |
PHQ baseline
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
12.44 |
11.76 |
13.13 |
0.35 |
6.35e-269 |
| Depressive and anxiety disorder |
5.67 |
5.46 |
5.88 |
0.11 |
0.00e+00 |
| Only depressive disorder |
3.56 |
3.29 |
3.84 |
0.14 |
5.09e-143 |
| Only anxiety disorder |
2.13 |
1.79 |
2.46 |
0.17 |
3.98e-35 |
| Eating disorders |
1.37 |
1.06 |
1.69 |
0.16 |
1.65e-17 |
| OCDs |
1.35 |
1.05 |
1.65 |
0.15 |
1.57e-18 |
| Psychotic and bipolar disorder |
0.22 |
-0.64 |
1.07 |
0.43 |
0.62 |
| Only psychotic disorder |
0.59 |
-0.16 |
1.33 |
0.38 |
0.12 |
| Only bipolar disorder |
1.49 |
1.04 |
1.95 |
0.23 |
1.54e-10 |
| PTSD |
1.90 |
1.62 |
2.18 |
0.14 |
2.74e-40 |
| ASD |
1.38 |
0.82 |
1.94 |
0.29 |
1.35e-06 |
| ADHD |
1.06 |
0.34 |
1.78 |
0.37 |
0.004 |
| Personality disorder |
3.21 |
2.81 |
3.60 |
0.20 |
1.20e-57 |
| Female |
0.82 |
0.62 |
1.02 |
0.10 |
8.40e-16 |
| Non-binary/Self-defined |
1.31 |
0.55 |
2.08 |
0.39 |
7.22e-04 |
| 19-25 years |
-3.88 |
-4.52 |
-3.24 |
0.33 |
9.39e-33 |
| 26-35 years |
-5.94 |
-6.54 |
-5.33 |
0.31 |
1.92e-82 |
| 36-45 years |
-6.53 |
-7.14 |
-5.93 |
0.31 |
4.27e-98 |
| 46-55 years |
-6.74 |
-7.34 |
-6.14 |
0.31 |
2.45e-106 |
| 56-65 years |
-7.49 |
-8.10 |
-6.88 |
0.31 |
8.88e-128 |
| 66-70 years |
-8.84 |
-9.62 |
-8.07 |
0.40 |
1.62e-109 |
| 71-75 years |
-8.41 |
-9.36 |
-7.45 |
0.49 |
2.75e-66 |
| 76+ years |
-8.64 |
-10.19 |
-7.08 |
0.79 |
1.93e-27 |
| Mixed or multiple ethnic origins |
0.43 |
-0.15 |
1.01 |
0.30 |
0.15 |
| Asian or Asian British |
0.41 |
-0.32 |
1.15 |
0.38 |
0.27 |
| African or African British |
-0.13 |
-1.38 |
1.11 |
0.63 |
0.83 |
| Other ethnicity |
0.63 |
-0.43 |
1.69 |
0.54 |
0.24 |
| Key worker |
-0.88 |
-1.04 |
-0.71 |
0.08 |
2.09e-25 |
| Time difference: Lockdown to baseline |
-0.20 |
-0.24 |
-0.16 |
0.02 |
4.62e-24 |
| Increased employment |
0.00 |
-0.41 |
0.41 |
0.21 |
1.00 |
| Furloughed |
-0.34 |
-0.64 |
-0.04 |
0.15 |
0.03 |
| employment_changeEmployment not changed |
-0.31 |
-0.55 |
-0.08 |
0.12 |
0.009 |
PHQ retro
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
4.10 |
3.84 |
4.37 |
0.14 |
4.96e-193 |
| phq.sum_score_retro |
0.68 |
0.66 |
0.69 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
2.68 |
2.53 |
2.83 |
0.07 |
3.84e-277 |
| Only depressive disorder |
1.69 |
1.52 |
1.86 |
0.09 |
2.24e-81 |
| Only anxiety disorder |
1.18 |
0.96 |
1.40 |
0.11 |
9.64e-27 |
| Eating disorders |
0.79 |
0.56 |
1.01 |
0.12 |
7.75e-12 |
| OCDs |
0.46 |
0.24 |
0.67 |
0.11 |
3.82e-05 |
| Psychotic and bipolar disorder |
0.02 |
-0.61 |
0.65 |
0.32 |
0.95 |
| Only psychotic disorder |
-0.05 |
-0.59 |
0.49 |
0.28 |
0.85 |
| Only bipolar disorder |
0.64 |
0.30 |
0.99 |
0.18 |
2.59e-04 |
| PTSD |
0.93 |
0.73 |
1.13 |
0.10 |
3.86e-19 |
| ASD |
0.55 |
0.15 |
0.95 |
0.20 |
0.007 |
| ADHD |
0.34 |
-0.19 |
0.86 |
0.27 |
0.21 |
| Personality disorder |
0.80 |
0.50 |
1.10 |
0.15 |
1.97e-07 |
| Female |
0.74 |
0.61 |
0.86 |
0.06 |
1.20e-30 |
| Non-binary/Self-defined |
0.54 |
0.03 |
1.05 |
0.26 |
0.04 |
| age_category_collapsed_reordered16-18 |
2.82 |
2.46 |
3.17 |
0.18 |
5.88e-55 |
| age_category_collapsed_reordered19-25 |
1.20 |
0.96 |
1.43 |
0.12 |
1.97e-23 |
| age_category_collapsed_reordered36-45 |
-0.59 |
-0.79 |
-0.40 |
0.10 |
3.85e-09 |
| age_category_collapsed_reordered46-55 |
-0.77 |
-0.95 |
-0.59 |
0.09 |
1.94e-16 |
| age_category_collapsed_reordered56-65 |
-1.16 |
-1.35 |
-0.97 |
0.10 |
3.13e-32 |
| age_category_collapsed_reordered66-70 |
-1.59 |
-1.86 |
-1.32 |
0.14 |
6.05e-31 |
| age_category_collapsed_reordered71-75 |
-1.75 |
-2.05 |
-1.45 |
0.15 |
7.25e-30 |
| age_category_collapsed_reordered76+ |
-1.77 |
-2.19 |
-1.35 |
0.21 |
1.04e-16 |
| Mixed or multiple ethnic origins |
0.12 |
-0.28 |
0.52 |
0.20 |
0.55 |
| Asian or Asian British |
0.00 |
-0.47 |
0.47 |
0.24 |
1.00 |
| African or African British |
-0.43 |
-1.32 |
0.46 |
0.46 |
0.34 |
| Other ethnicity |
0.48 |
-0.24 |
1.20 |
0.37 |
0.19 |
| Key worker |
0.11 |
-0.02 |
0.24 |
0.07 |
0.10 |
| Retired |
-0.19 |
-0.39 |
0.00 |
0.10 |
0.06 |
| Student |
0.44 |
0.15 |
0.74 |
0.15 |
0.003 |
| Unemployed |
0.65 |
0.40 |
0.90 |
0.13 |
2.92e-07 |
| Time difference: Lockdown to baseline |
-0.22 |
-0.25 |
-0.19 |
0.01 |
4.59e-58 |
PHQ prepan
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.51 |
1.66 |
3.37 |
0.44 |
7.90e-09 |
| phq.sum_score_prepan |
0.54 |
0.53 |
0.56 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
1.25 |
0.61 |
1.90 |
0.33 |
1.29e-04 |
| Only depressive disorder |
0.80 |
0.11 |
1.49 |
0.35 |
0.02 |
| Only anxiety disorder |
0.20 |
-0.53 |
0.92 |
0.37 |
0.59 |
| Eating disorders |
0.95 |
0.63 |
1.27 |
0.16 |
8.00e-09 |
| OCDs |
0.51 |
0.21 |
0.82 |
0.15 |
7.98e-04 |
| Psychotic and bipolar disorder |
-0.82 |
-1.73 |
0.09 |
0.46 |
0.08 |
| Only psychotic disorder |
0.14 |
-0.59 |
0.88 |
0.38 |
0.70 |
| Only bipolar disorder |
0.27 |
-0.17 |
0.72 |
0.23 |
0.23 |
| PTSD |
0.57 |
0.28 |
0.86 |
0.15 |
9.92e-05 |
| ASD |
0.66 |
0.06 |
1.25 |
0.30 |
0.03 |
| ADHD |
0.35 |
-0.47 |
1.16 |
0.42 |
0.41 |
| Personality disorder |
0.90 |
0.49 |
1.31 |
0.21 |
1.73e-05 |
| Female |
0.15 |
-0.12 |
0.41 |
0.13 |
0.28 |
| Non-binary/Self-defined |
0.28 |
-0.48 |
1.03 |
0.38 |
0.47 |
| age_category_collapsed_reordered16-18 |
1.92 |
1.28 |
2.55 |
0.32 |
3.07e-09 |
| age_category_collapsed_reordered19-25 |
0.88 |
0.54 |
1.23 |
0.18 |
5.57e-07 |
| age_category_collapsed_reordered36-45 |
-0.26 |
-0.56 |
0.05 |
0.15 |
0.10 |
| age_category_collapsed_reordered46-55 |
-0.54 |
-0.83 |
-0.24 |
0.15 |
3.83e-04 |
| age_category_collapsed_reordered56-65 |
-1.03 |
-1.39 |
-0.66 |
0.19 |
3.50e-08 |
| age_category_collapsed_reordered66-70 |
-1.82 |
-2.47 |
-1.17 |
0.33 |
4.80e-08 |
| age_category_collapsed_reordered71-75 |
-2.31 |
-3.14 |
-1.48 |
0.42 |
4.64e-08 |
| age_category_collapsed_reordered76+ |
-1.71 |
-3.18 |
-0.23 |
0.75 |
0.02 |
| Mixed or multiple ethnic origins |
0.25 |
-0.43 |
0.92 |
0.34 |
0.48 |
| Asian or Asian British |
-0.70 |
-1.78 |
0.38 |
0.55 |
0.20 |
| African or African British |
-0.20 |
-1.99 |
1.60 |
0.92 |
0.83 |
| Other ethnicity |
0.16 |
-0.87 |
1.19 |
0.53 |
0.76 |
| Key worker |
0.06 |
-0.18 |
0.29 |
0.12 |
0.64 |
| Retired |
0.40 |
-0.05 |
0.84 |
0.23 |
0.08 |
| Student |
0.55 |
0.07 |
1.02 |
0.24 |
0.02 |
| Unemployed |
1.42 |
1.05 |
1.80 |
0.19 |
1.81e-13 |
| Time difference: Lockdown to baseline |
0.08 |
0.01 |
0.14 |
0.03 |
0.01 |
PHQ retro GLAD and EDGI sensitivity
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
4.23 |
3.43 |
5.04 |
0.41 |
7.51e-25 |
| phq.sum_score_retro |
0.66 |
0.65 |
0.68 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
0.92 |
0.32 |
1.53 |
0.31 |
0.003 |
| Only depressive disorder |
0.66 |
0.00 |
1.31 |
0.34 |
0.05 |
| Only anxiety disorder |
-0.35 |
-1.04 |
0.33 |
0.35 |
0.31 |
| Eating disorders |
0.83 |
0.52 |
1.14 |
0.16 |
1.11e-07 |
| OCDs |
0.40 |
0.11 |
0.69 |
0.15 |
0.006 |
| Psychotic and bipolar disorder |
-0.43 |
-1.30 |
0.44 |
0.44 |
0.33 |
| Only psychotic disorder |
-0.13 |
-0.84 |
0.57 |
0.36 |
0.71 |
| Only bipolar disorder |
0.28 |
-0.15 |
0.70 |
0.22 |
0.20 |
| PTSD |
0.80 |
0.52 |
1.07 |
0.14 |
1.11e-08 |
| ASD |
0.36 |
-0.20 |
0.93 |
0.29 |
0.21 |
| ADHD |
0.36 |
-0.42 |
1.14 |
0.40 |
0.37 |
| Personality disorder |
0.78 |
0.39 |
1.18 |
0.20 |
9.15e-05 |
| Female |
0.30 |
0.05 |
0.55 |
0.13 |
0.02 |
| Non-binary/Self-defined |
0.04 |
-0.68 |
0.76 |
0.37 |
0.90 |
| age_category_collapsed_reordered16-18 |
1.94 |
1.34 |
2.54 |
0.31 |
3.00e-10 |
| age_category_collapsed_reordered19-25 |
1.09 |
0.76 |
1.42 |
0.17 |
8.79e-11 |
| age_category_collapsed_reordered36-45 |
-0.50 |
-0.78 |
-0.21 |
0.15 |
7.27e-04 |
| age_category_collapsed_reordered46-55 |
-0.66 |
-0.94 |
-0.38 |
0.14 |
4.35e-06 |
| age_category_collapsed_reordered56-65 |
-1.39 |
-1.74 |
-1.04 |
0.18 |
5.54e-15 |
| age_category_collapsed_reordered66-70 |
-2.03 |
-2.65 |
-1.40 |
0.32 |
2.01e-10 |
| age_category_collapsed_reordered71-75 |
-2.63 |
-3.42 |
-1.84 |
0.40 |
7.33e-11 |
| age_category_collapsed_reordered76+ |
-2.55 |
-3.97 |
-1.13 |
0.72 |
4.29e-04 |
| Mixed or multiple ethnic origins |
-0.07 |
-0.71 |
0.58 |
0.33 |
0.84 |
| Asian or Asian British |
-0.29 |
-1.32 |
0.74 |
0.53 |
0.58 |
| African or African British |
0.10 |
-1.62 |
1.81 |
0.87 |
0.91 |
| Other ethnicity |
0.27 |
-0.71 |
1.25 |
0.50 |
0.59 |
| Key worker |
0.08 |
-0.14 |
0.31 |
0.12 |
0.46 |
| Retired |
0.11 |
-0.31 |
0.54 |
0.22 |
0.60 |
| Student |
0.49 |
0.04 |
0.94 |
0.23 |
0.03 |
| Unemployed |
0.81 |
0.45 |
1.17 |
0.19 |
1.20e-05 |
| Time difference: Lockdown to baseline |
0.00 |
-0.05 |
0.06 |
0.03 |
0.91 |
OCIR baseline
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
24.47 |
21.76 |
27.18 |
1.38 |
3.69e-67 |
| Depressive and anxiety disorder |
2.81 |
1.69 |
3.93 |
0.57 |
9.40e-07 |
| Only depressive disorder |
0.24 |
-1.30 |
1.78 |
0.79 |
0.76 |
| Only anxiety disorder |
0.59 |
-0.97 |
2.15 |
0.80 |
0.46 |
| Eating disorders |
0.12 |
-1.14 |
1.38 |
0.64 |
0.86 |
| OCDs |
6.83 |
5.72 |
7.94 |
0.56 |
4.43e-33 |
| Psychotic and bipolar disorder |
6.66 |
3.70 |
9.61 |
1.51 |
1.03e-05 |
| Only psychotic disorder |
4.43 |
1.67 |
7.18 |
1.41 |
0.002 |
| Only bipolar disorder |
3.18 |
1.26 |
5.09 |
0.98 |
0.001 |
| PTSD |
2.60 |
1.50 |
3.70 |
0.56 |
3.96e-06 |
| ASD |
7.81 |
5.72 |
9.90 |
1.07 |
2.78e-13 |
| ADHD |
2.39 |
-0.38 |
5.15 |
1.41 |
0.09 |
| Personality disorder |
3.45 |
2.01 |
4.90 |
0.74 |
3.03e-06 |
| Female |
-0.77 |
-1.90 |
0.36 |
0.57 |
0.18 |
| Non-binary/Self-defined |
-1.47 |
-4.53 |
1.58 |
1.56 |
0.35 |
| 19-25 years |
-6.55 |
-8.87 |
-4.24 |
1.18 |
3.00e-08 |
| 26-35 years |
-8.19 |
-10.39 |
-5.98 |
1.12 |
4.12e-13 |
| 36-45 years |
-8.18 |
-10.43 |
-5.93 |
1.15 |
1.21e-12 |
| 46-55 years |
-8.04 |
-10.24 |
-5.83 |
1.13 |
1.11e-12 |
| 56-65 years |
-8.48 |
-10.73 |
-6.24 |
1.14 |
1.52e-13 |
| 66-70 years |
-9.11 |
-12.88 |
-5.34 |
1.92 |
2.24e-06 |
| 71-75 years |
-10.18 |
-15.42 |
-4.93 |
2.68 |
1.45e-04 |
| 76+ years |
-9.08 |
-18.09 |
-0.06 |
4.60 |
0.05 |
| Mixed or multiple ethnic origins |
0.21 |
-2.38 |
2.80 |
1.32 |
0.87 |
| Asian or Asian British |
2.61 |
-1.52 |
6.73 |
2.10 |
0.22 |
| African or African British |
-0.12 |
-6.84 |
6.59 |
3.43 |
0.97 |
| Other ethnicity |
2.36 |
-1.58 |
6.30 |
2.01 |
0.24 |
| Key worker |
-1.72 |
-2.53 |
-0.91 |
0.41 |
3.26e-05 |
| Time difference: Lockdown to baseline |
-0.41 |
-0.59 |
-0.23 |
0.09 |
1.04e-05 |
| Increased employment |
1.67 |
-0.31 |
3.66 |
1.01 |
0.10 |
| Furloughed |
-0.02 |
-1.40 |
1.36 |
0.70 |
0.98 |
| employment_changeEmployment not changed |
0.18 |
-0.92 |
1.27 |
0.56 |
0.75 |
OCIR retro
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
12.95 |
11.63 |
14.27 |
0.67 |
3.15e-79 |
| ocir.sum_score_retro |
0.74 |
0.71 |
0.76 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
-1.13 |
-1.87 |
-0.39 |
0.38 |
0.003 |
| Only depressive disorder |
-0.96 |
-1.95 |
0.03 |
0.51 |
0.06 |
| Only anxiety disorder |
-0.18 |
-1.18 |
0.83 |
0.51 |
0.73 |
| Eating disorders |
0.05 |
-0.83 |
0.92 |
0.45 |
0.92 |
| OCDs |
1.93 |
1.16 |
2.70 |
0.39 |
9.08e-07 |
| Psychotic and bipolar disorder |
3.06 |
1.04 |
5.09 |
1.03 |
0.003 |
| Only psychotic disorder |
0.73 |
-1.17 |
2.63 |
0.97 |
0.45 |
| Only bipolar disorder |
0.41 |
-0.89 |
1.72 |
0.67 |
0.54 |
| PTSD |
0.49 |
-0.27 |
1.25 |
0.39 |
0.21 |
| ASD |
2.41 |
0.99 |
3.83 |
0.72 |
8.79e-04 |
| ADHD |
1.92 |
-0.04 |
3.88 |
1.00 |
0.05 |
| Personality disorder |
0.60 |
-0.48 |
1.68 |
0.55 |
0.28 |
| Female |
-0.02 |
-0.75 |
0.71 |
0.37 |
0.96 |
| Non-binary/Self-defined |
-0.31 |
-2.32 |
1.71 |
1.03 |
0.77 |
| age_category_collapsed_reordered16-18 |
5.16 |
3.75 |
6.58 |
0.72 |
1.09e-12 |
| age_category_collapsed_reordered19-25 |
0.15 |
-0.84 |
1.14 |
0.50 |
0.77 |
| age_category_collapsed_reordered36-45 |
-0.26 |
-1.17 |
0.66 |
0.47 |
0.58 |
| age_category_collapsed_reordered46-55 |
-0.01 |
-0.86 |
0.85 |
0.44 |
0.99 |
| age_category_collapsed_reordered56-65 |
1.20 |
0.28 |
2.12 |
0.47 |
0.01 |
| age_category_collapsed_reordered66-70 |
1.91 |
0.45 |
3.38 |
0.75 |
0.01 |
| age_category_collapsed_reordered71-75 |
1.57 |
-0.16 |
3.30 |
0.88 |
0.08 |
| age_category_collapsed_reordered76+ |
-0.49 |
-3.72 |
2.74 |
1.65 |
0.76 |
| Mixed or multiple ethnic origins |
1.09 |
-0.64 |
2.81 |
0.88 |
0.22 |
| Asian or Asian British |
3.72 |
1.25 |
6.19 |
1.26 |
0.003 |
| African or African British |
-0.78 |
-6.52 |
4.95 |
2.93 |
0.79 |
| Other ethnicity |
1.56 |
-0.95 |
4.07 |
1.28 |
0.22 |
| Key worker |
-0.09 |
-0.74 |
0.56 |
0.33 |
0.78 |
| Retired |
-0.33 |
-1.37 |
0.71 |
0.53 |
0.54 |
| Student |
-0.26 |
-1.50 |
0.99 |
0.63 |
0.69 |
| Unemployed |
1.38 |
0.38 |
2.38 |
0.51 |
0.007 |
| Time difference: Lockdown to baseline |
-1.36 |
-1.48 |
-1.23 |
0.06 |
1.07e-95 |
OCIR prepan
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
5.32 |
-0.24 |
10.88 |
2.83 |
0.06 |
| pcl.sum_score_prepan |
0.59 |
0.50 |
0.69 |
0.05 |
1.38e-31 |
| Depressive and anxiety disorder |
-4.84 |
-9.28 |
-0.40 |
2.26 |
0.03 |
| Only depressive disorder |
-5.59 |
-10.41 |
-0.77 |
2.46 |
0.02 |
| Only anxiety disorder |
-6.09 |
-10.88 |
-1.29 |
2.45 |
0.01 |
| Eating disorders |
1.14 |
-0.47 |
2.75 |
0.82 |
0.17 |
| OCDs |
6.27 |
4.89 |
7.64 |
0.70 |
1.14e-18 |
| Psychotic and bipolar disorder |
3.38 |
-0.69 |
7.44 |
2.07 |
0.10 |
| Only psychotic disorder |
0.48 |
-2.85 |
3.81 |
1.70 |
0.78 |
| Only bipolar disorder |
2.57 |
0.27 |
4.86 |
1.17 |
0.03 |
| PTSD |
-0.12 |
-1.54 |
1.31 |
0.72 |
0.87 |
| ASD |
5.30 |
2.29 |
8.31 |
1.54 |
5.72e-04 |
| ADHD |
0.33 |
-4.25 |
4.90 |
2.33 |
0.89 |
| Personality disorder |
1.91 |
-0.02 |
3.85 |
0.99 |
0.05 |
| Female |
-0.08 |
-1.67 |
1.51 |
0.81 |
0.92 |
| Non-binary/Self-defined |
1.12 |
-2.76 |
5.00 |
1.98 |
0.57 |
| age_category_collapsed_reordered16-18 |
2.56 |
-1.23 |
6.36 |
1.94 |
0.19 |
| age_category_collapsed_reordered19-25 |
0.72 |
-1.10 |
2.55 |
0.93 |
0.44 |
| age_category_collapsed_reordered36-45 |
-0.53 |
-2.20 |
1.14 |
0.85 |
0.53 |
| age_category_collapsed_reordered46-55 |
0.77 |
-0.87 |
2.41 |
0.84 |
0.36 |
| age_category_collapsed_reordered56-65 |
-1.11 |
-3.12 |
0.90 |
1.03 |
0.28 |
| age_category_collapsed_reordered66-70 |
-1.82 |
-5.71 |
2.06 |
1.98 |
0.36 |
| age_category_collapsed_reordered71-75 |
-3.28 |
-8.47 |
1.91 |
2.65 |
0.22 |
| age_category_collapsed_reordered76+ |
0.44 |
-10.44 |
11.33 |
5.55 |
0.94 |
| Mixed or multiple ethnic origins |
2.03 |
-1.41 |
5.47 |
1.75 |
0.25 |
| Asian or Asian British |
6.17 |
-1.43 |
13.77 |
3.88 |
0.11 |
| African or African British |
7.29 |
-7.76 |
22.35 |
7.68 |
0.34 |
| Other ethnicity |
4.41 |
-0.67 |
9.48 |
2.59 |
0.09 |
| Key worker |
0.65 |
-0.69 |
1.98 |
0.68 |
0.34 |
| Retired |
2.90 |
0.49 |
5.31 |
1.23 |
0.02 |
| Student |
1.25 |
-1.29 |
3.78 |
1.29 |
0.34 |
| Unemployed |
3.78 |
1.93 |
5.64 |
0.95 |
6.51e-05 |
| Time difference: Lockdown to baseline |
0.29 |
-0.04 |
0.63 |
0.17 |
0.09 |
PCL baseline
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
13.97 |
13.37 |
14.57 |
0.31 |
0.00e+00 |
| Depressive and anxiety disorder |
5.35 |
5.17 |
5.54 |
0.09 |
0.00e+00 |
| Only depressive disorder |
2.83 |
2.59 |
3.07 |
0.12 |
9.66e-118 |
| Only anxiety disorder |
2.61 |
2.32 |
2.91 |
0.15 |
1.19e-66 |
| Eating disorders |
0.68 |
0.41 |
0.96 |
0.14 |
1.36e-06 |
| OCDs |
1.18 |
0.92 |
1.44 |
0.13 |
1.95e-18 |
| Psychotic and bipolar disorder |
1.05 |
0.30 |
1.80 |
0.38 |
0.006 |
| Only psychotic disorder |
0.73 |
0.08 |
1.38 |
0.33 |
0.03 |
| Only bipolar disorder |
1.23 |
0.83 |
1.64 |
0.21 |
1.87e-09 |
| PTSD |
2.71 |
2.46 |
2.95 |
0.13 |
1.68e-101 |
| ASD |
0.88 |
0.39 |
1.37 |
0.25 |
4.52e-04 |
| ADHD |
0.76 |
0.12 |
1.39 |
0.32 |
0.02 |
| Personality disorder |
2.69 |
2.35 |
3.03 |
0.18 |
1.15e-52 |
| Female |
0.70 |
0.52 |
0.87 |
0.09 |
6.52e-15 |
| Non-binary/Self-defined |
1.12 |
0.46 |
1.79 |
0.34 |
9.70e-04 |
| 19-25 years |
-2.09 |
-2.65 |
-1.53 |
0.29 |
2.37e-13 |
| 26-35 years |
-3.83 |
-4.35 |
-3.30 |
0.27 |
1.54e-45 |
| 36-45 years |
-4.42 |
-4.95 |
-3.89 |
0.27 |
2.09e-59 |
| 46-55 years |
-4.67 |
-5.20 |
-4.14 |
0.27 |
1.92e-67 |
| 56-65 years |
-5.17 |
-5.70 |
-4.64 |
0.27 |
1.97e-80 |
| 66-70 years |
-6.01 |
-6.69 |
-5.33 |
0.35 |
1.01e-66 |
| 71-75 years |
-5.71 |
-6.55 |
-4.87 |
0.43 |
1.02e-40 |
| 76+ years |
-5.01 |
-6.39 |
-3.63 |
0.70 |
9.99e-13 |
| Mixed or multiple ethnic origins |
0.56 |
0.05 |
1.07 |
0.26 |
0.03 |
| Asian or Asian British |
0.90 |
0.26 |
1.55 |
0.33 |
0.006 |
| African or African British |
0.60 |
-0.49 |
1.69 |
0.56 |
0.28 |
| Other ethnicity |
0.63 |
-0.30 |
1.56 |
0.47 |
0.18 |
| Key worker |
-0.68 |
-0.83 |
-0.54 |
0.07 |
3.11e-20 |
| Time difference: Lockdown to baseline |
0.00 |
-0.03 |
0.03 |
0.02 |
0.99 |
| Increased employment |
-0.19 |
-0.55 |
0.17 |
0.18 |
0.31 |
| Furloughed |
-0.48 |
-0.75 |
-0.22 |
0.13 |
3.47e-04 |
| employment_changeEmployment not changed |
-0.51 |
-0.72 |
-0.31 |
0.10 |
1.00e-06 |
#PCL prepan ### Model 1b: Overlapping disorders, Adjusted Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
6.29 |
5.43 |
7.15 |
0.44 |
3.13e-46 |
| pcl.sum_score_prepan |
0.50 |
0.48 |
0.52 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
0.64 |
0.01 |
1.27 |
0.32 |
0.05 |
| Only depressive disorder |
-0.13 |
-0.82 |
0.55 |
0.35 |
0.70 |
| Only anxiety disorder |
-0.65 |
-1.36 |
0.07 |
0.36 |
0.08 |
| Eating disorders |
0.43 |
0.11 |
0.75 |
0.16 |
0.008 |
| OCDs |
0.46 |
0.16 |
0.76 |
0.15 |
0.002 |
| Psychotic and bipolar disorder |
-0.23 |
-1.12 |
0.65 |
0.45 |
0.61 |
| Only psychotic disorder |
-0.13 |
-0.86 |
0.60 |
0.37 |
0.73 |
| Only bipolar disorder |
0.44 |
0.00 |
0.88 |
0.23 |
0.05 |
| PTSD |
0.80 |
0.51 |
1.09 |
0.15 |
5.26e-08 |
| ASD |
0.45 |
-0.14 |
1.04 |
0.30 |
0.14 |
| ADHD |
0.34 |
-0.48 |
1.16 |
0.42 |
0.41 |
| Personality disorder |
0.65 |
0.25 |
1.06 |
0.21 |
0.002 |
| Female |
0.52 |
0.25 |
0.78 |
0.13 |
1.05e-04 |
| Non-binary/Self-defined |
0.52 |
-0.22 |
1.27 |
0.38 |
0.17 |
| age_category_collapsed_reordered16-18 |
1.15 |
0.52 |
1.77 |
0.32 |
3.18e-04 |
| age_category_collapsed_reordered19-25 |
0.87 |
0.53 |
1.21 |
0.17 |
6.28e-07 |
| age_category_collapsed_reordered36-45 |
-0.59 |
-0.89 |
-0.29 |
0.15 |
1.07e-04 |
| age_category_collapsed_reordered46-55 |
-0.71 |
-1.00 |
-0.41 |
0.15 |
2.25e-06 |
| age_category_collapsed_reordered56-65 |
-0.83 |
-1.19 |
-0.47 |
0.18 |
6.52e-06 |
| age_category_collapsed_reordered66-70 |
-1.59 |
-2.24 |
-0.95 |
0.33 |
1.33e-06 |
| age_category_collapsed_reordered71-75 |
-1.94 |
-2.76 |
-1.12 |
0.42 |
3.66e-06 |
| age_category_collapsed_reordered76+ |
-1.53 |
-2.98 |
-0.07 |
0.74 |
0.04 |
| Mixed or multiple ethnic origins |
0.35 |
-0.31 |
1.02 |
0.34 |
0.30 |
| Asian or Asian British |
0.53 |
-0.55 |
1.62 |
0.55 |
0.33 |
| African or African British |
0.37 |
-1.39 |
2.14 |
0.90 |
0.68 |
| Other ethnicity |
0.19 |
-0.82 |
1.21 |
0.52 |
0.71 |
| Key worker |
-0.25 |
-0.48 |
-0.01 |
0.12 |
0.04 |
| Retired |
-0.03 |
-0.47 |
0.41 |
0.22 |
0.88 |
| Student |
0.27 |
-0.20 |
0.74 |
0.24 |
0.26 |
| Unemployed |
1.21 |
0.83 |
1.58 |
0.19 |
2.20e-10 |
| Time difference: Lockdown to baseline |
0.10 |
0.04 |
0.16 |
0.03 |
7.03e-04 |
Forest Plots
functions that assign global variables and need to be in the markdown
run regression models to get normal output
###Standardise linear variables
Run models
no explan var
###Subset retrospective data by samples
add a single “other ethnicity individual” as a jitter for NBR so this category remains included wihout adding explanation.
Create data frames and plots using functions and models generated above.
no explanatory variables
With no control for retro or prepan (no explanatory variables)
Forest plots
palette
disorder
title: Predictors of pandemic symptoms controlling for prepandemic symptoms 
Predictors of pandemic symptoms controlling for retrospective symptoms
Warning: Removed 1 rows containing missing values (geom_point).
Warning: Removed 2 rows containing missing values (geom_point).
